Abstract:
BACKGROUND:Multi-parametric magnetic resonance imaging (mpMRI)-directed biopsy for prostate cancer (PC) diagnosis improves the detection of clinically significant prostate cancer (CSPC) and decreases the rate of over-diagnosis of insignificant disease. The aim of this study was to investigate the value of mpMRI combined with prostate specific antigen density (PSAD) in the decision making related to the biopsy. METHODS:mpMRI and mpMRI/transrectal ultrasound fusion targeted biopsies with subsequent systematic biopsies were performed in 397 patients (223 biopsy-naïve and 174 with a previous biopsy). Detection rates of (CSPC) and insignificant PC were stratified using the PIRADS score, and the number of avoidable biopsies and missed (CSPC) were plotted against PSAD values of 0.1-0.5 ng/mL2. RESULTS:PIRADS <3 and PSAD <0.2 ng/mL2 were the safest criteria for not performing a biopsy. When applied to the biopsy-naïve group, 21.5% (48/223) of the biopsies could have been avoided and 3.7% (3/82) of CSPC would have been missed. In the repeat biopsy group, 12.6% (22/174) of biopsies could have been avoided and 6.9% (4/58) of (CSPC) would have been missed. CONCLUSIONS:A combination of mpMRI and PSAD might reduce the number of biopsies performed with the cost of missing <4% of CSPC.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Záleský M,Stejskal J,Adamcova V,Hrbáček J,Minarik I,Pavlicko A,Votrubova J,Babjuk M,Zachoval Rdoi
10.1159/000500350subject
Has Abstractpub_date
2019-01-01 00:00:00pages
33-40issue
1eissn
0042-1138issn
1423-0399pii
000500350journal_volume
103pub_type
杂志文章abstract::At the Institute of Urology, University of Padova, 125 patients with multifocal superficial bladder cancer underwent treatment with intravesical Mitomycin C (MMC; 1 weekly instillation of 40 mg for 8 consecutive weeks) between January 1982 and December 1988. Eighty-four patients had multifocal papillary tumors (stages...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282320
更新日期:1992-01-01 00:00:00
abstract::24 h urinary pyrophosphate excretion was studied in 20 normal healthy subjects and 75 idiopathic stone formers from north-western regions of India. The mean 24-hour urinary excretion of pyrophosphate was significantly low in stone formers (50.67 +/- 2.16 mumol/24 h) as compared to that of normal subjects (71.46 +/- 5....
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000282364
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and feasibility of percutaneous tract dilation by the one-stage method in preschool children. METHODS:Between April 2009 and February 2013, all preschool (<6 years) children who were candidates for percutaneous nephrolithotomy were enrolled in this prospective study. Patients were rand...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000356327
更新日期:2014-01-01 00:00:00
abstract::The first case of carcinosarcoma in the spermatic cord is reported in a 40-year-old man. The tumor was a 2.5 X 2 cm pseudoencapsulated formation located in the connective tissue of the spermatic cord among the blood vessels. Light microscopy examination of the neoplasm revealed two different histological patterns: epi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281727
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Cystic renal tumors are a diagnostic and therapeutic challenge. Cystic nephroma (CN), cystic partially differentiated nephroblastoma (CPDN) and cystic Wilms' tumor (CWT) are a spectrum with CN at the benign end, CWT at the malignant end and CPDN in the intermediate position. CN and stage 1 CPDN are often tre...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000176028
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The internet is an emerging source of information for prostate cancer (PCa) patients. Since little is known about the quality of information on PCa provided online, we investigated its accordance to the latest European Association of Urology (EAU) guidelines. METHODS:A total of 89 German web pages were incl...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000487146
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:To assess the association of prostate volume index (PVI), defined as the ratio of the central transition zone volume to the peripheral zone volume, and prostatic chronic inflammation (PCI) as predictors of prostate cancer (PCA) risk in patients presenting with normal digital rectal exam and prostate-specif...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000502659
更新日期:2019-01-01 00:00:00
abstract::Considerable progress has been made regarding pathogenesis, diagnosis and conservative management of urolithiasis. The cause of the disease can now be determined in nearly 80% of the patients. New stone formation may be prevented in the majority of patients by selective medical treatment. The metabolic, physicochemica...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000281240
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Radical cystectomy (RC) still poses a significant risk for mortality and morbidity. OBJECTIVES:We compared in-hospital outcomes after RC in the United States and -Germany using population-based data. METHODS:We compared data from the US Nationwide Inpatient Sample to the German hospital billing database. M...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000496347
更新日期:2019-01-01 00:00:00
abstract::Both under physiologic conditions and after short-term ischemia (1-3 min) kallikrein and locally synthesized prostaglandins contribute to control renal blood flow. In the present experiment the antiproteases aprotinin and gabexate-mesilate were administered to rabbits in an attempt to show whether the hemodynamic chan...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280880
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVES:To assess the effect of neoadjuvant hormone treatment before radical prostatectomy on: tumor/prostate volume, prostate-specific antigen (PSA) and testosterone levels, surgical margin status and tumor stage, and the ease of surgery following treatment. METHODS:Patients with clinically localized prostatic car...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000077113
更新日期:2004-01-01 00:00:00
abstract::Testicular sperm extraction and intracytoplasmic sperm injection (TESE-ICSI) is a frequently used therapeutic option in azoospermic males. Genetic imprinting is a mechanism of gene regulation - mediated by the methylation of deoxyribonucleic acids (DNA) - by which only one of the parental copies of a gene is expressed...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000050972
更新日期:2001-01-01 00:00:00
abstract:INTRODUCTION:We aimed to assess the outcome of free tube graft urethroplasty for single-stage repair of hypospadias with chordee in children. MATERIALS AND METHODS:We retrospectively evaluated a series of 56 patients (16 months to 9 years old, median 24 months) who underwent free graft urethroplasty for repair of hypo...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000504146
更新日期:2020-01-01 00:00:00
abstract::Twenty-five patients with transitional cell carcinoma of the bladder have been treated with combined therapy consisting of microwave regional coagulation and intracavitary irradiation. A remote-controlled after-loading system was utilized for the radiation therapy. The follow-up period ranged from 6 to 19 months with ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281330
更新日期:1988-01-01 00:00:00
abstract::Dependent drainage of a lower pole pyelocaliceal diverticulum was achieved by uretero-diverticulostomy in eight patients who already had compromised renal function due to bilateral megaureters or posterior urethral valves. This procedure preserves all functional renal parenchyma and the ureteropelvic junction is left ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280071
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVES:There is a considerable lack of consensus regarding indications and long-term efficacy of the many techniques for treating urinary stress incontinence. We report the long-term results of a modified pubovaginal sling procedure. METHODS:From 1989 to 1998, 129 consecutive patients underwent a pubovaginal sling...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000077685
更新日期:2004-01-01 00:00:00
abstract::Amputation of the penis is by no means the quickest and least invasive of the surgical methods of treating penis carcinoma. Radiation therapy has the advantage of preserving the integrity of the penis and does not render a later operation of the penis impossible. Regional lymph node metastases should be removed surgic...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280899
更新日期:1983-01-01 00:00:00
abstract::Varicocele is one of the causes of male infertility. Treatment aims to improve the chance of conception despite lasting controversies about benefits of varicocele repair on fertility. Many techniques have been described for varicocele management including the antegrade scrotal sclerotherapy (ASS). Interestingly, ASS i...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000481831
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Mini percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) are well-established techniques with little morbidity. The combined use of standard PCNL and the mini-PCNL or the RIRS technique was evaluated and compared to investigate their own role in the management of staghorn calc...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000360708
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:To compare the semen quality score and the seminal oxidative stress reactive oxygen species (ROS) and total antioxidant capacity (ROS-TAC score) in men with idiopathic infertility with normal donors and to a known group of fertile and infertile men. MATERIAL AND METHODS:Principal component analysis was ap...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000151401
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To assess clinical outcomes and reimbursement costs of open and robotic-assisted radical prostatectomies in Germany. METHODS:Perioperative data of 499 open (2003-2006) and 932 (2008-2010) robotic-assisted radical prostatectomies as well as longitudinal reimbursement costs of an anonymized health insurance rese...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000431104
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Our aim was to determine the safety and feasibility of catheter removal on the first morning after transurethral prostatectomy. METHODS:Fifty-four patients who underwent transurethral prostatectomy were included in a prospective study. The decision to remove the catheters on the first morning after surgery w...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000048428
更新日期:2002-01-01 00:00:00
abstract:INTRODUCTION:There is a lack of data regarding the appropriateness of transperitoneal and retroperitoneal approaches for right-sided laparoscopic adrenalectomy. The aim of this study was to determine whether there is any difference between right-sided transperitoneal laparoscopic adrenalectomy (TLA) and retroperitoneal...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000357627
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To investigate patients' opinions on the degree of pain during shock wave lithotripsy, and the need for analgesics in patients with urinary stone. METHODS:A prospective questionnaire study involving subjective pain assessment during and just after shock wave lithotripsy was performed in consecutive patients ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000082710
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:The urinary bladder is commonly involved in pelvic malignancy. The incidence of apparent extension into adjacent organs in locally advanced colorectal malignancy is 5-12%. It is not known with other pelvic malignancy. No guidelines are available for its management. Often a dilemma exists between cystectomy...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000092929
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:Urethral valves can be of enormous clinical importance. Both the prognosis for an affected fetus and the indication for a prenatal therapeutic intervention depend to a high degree on the accuracy of the prenatal diagnosis. PATIENTS AND METHODS:The sonographic findings and the results of the postnatal diag...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000081586
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:To assess the association between the development of a urethral stricture (US) and disease-free survival for patients with localized prostate cancer treated with high-intensity focused ultrasound (HIFU). PATIENTS AND METHODS:Patients with clinical stage T1-T2N0M0 prostate cancer were eligible for treatment wit...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000330909
更新日期:2011-01-01 00:00:00
abstract::Clinical and experimental investigations seem to underline the important role of fatty acids in the pathogenesis of hypercalciuria, a well-known risk factor for lithogenesis. To evaluate the relationships between the previously reported increase in plasma phospholipid arachidonic acid level and the factors responsible...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000087161
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study is to clarify the relationship of erectile dysfunction (ED) and diabetes mellitus (DM) parameters (referred to with '1'), including peripheral neuropathy (referred to with '2'). METHODS:(1) The DM parameters including age, serum levels of blood sugar, hemoglobin A1c, duration of DM a...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000327991
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:To investigate whether congenital renal vein anomalies are involved in the etiology of hematuria by analyzing abdominal multidetector computed tomography (MDCT) results. METHODS:Six hundred and eighty patients undergoing MDCT for various abdominal pathologies in whom possible causes of hematuria were exclud...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000365664
更新日期:2015-01-01 00:00:00