Clinicopathological study on end-stage reflux nephropathy in renal-transplanted children.

Abstract:

:Five children with end-stage reflux nephropathy underwent kidney transplantation at our clinic. Reflux nephropathy was studied clinically and histologically. All children had proteinuria before starting hemodialysis, and hypertension was present in 2 cases. Three children underwent antireflux operations prior to transplantation. The original kidneys exhibiting reflux were removed during renal transplantation. All original kidneys exhibited atrophy and scarring. Focal and segmental glomerulosclerosis was found in 4 cases. PAS deposition in the interstitium, suggestive of Tamm-Horsfall glycoprotein, was found in all cases. No recurrent signs of focal and segmental glomerulosclerosis have been found in the children who have been followed up from 1 to 6 years after transplantation.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Kunikata S,Ishii T,Nishioka T,Uemura T,Wakabayashi A,Kanda H,Matsuura T,Kohri K,Akiyama T,Kurita T

doi

10.1159/000281672

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

70-4

issue

2

eissn

0042-1138

issn

1423-0399

journal_volume

45

pub_type

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