Effect of experimental microvascular orchidopexy on testosterone secretion in the dog.

Abstract:

:This study was undertaken to investigate the endocrine function of the testis that was autotransplanted by microvascular techniques in 10 healthy dogs. After a control period of 4 weeks, hemicastration was carried out, and 4 weeks later the experimental orchidopexy was done. Finally, the transplanted testis was removed after another 4 weeks. Peripheral blood testosterone levels were measured at weekly intervals during the control period, after hemicastration, after autotransplantation and after removal of the transplanted testis. 1 week before each operation, 500 IU human chorionic gonadotrophin (HCG) was given intravenously and the peripheral testosterone levels were determined after 2 and 24 h. During each operation a testicular venous blood sample was taken for testosterone measurements. No differences were found between the basal and HCG-stimulated peripheral plasma levels of testosterone after the hemicastration and the orchidopexy in comparison with the values during the control period. There was a statistically significant positive correlation between the testosterone levels in the testicular venous and peripheral plasma samples. It was concluded that microvascular anastomosis was successful in every case.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Garibyan H,de Jong FH,Klopper PJ,van der Molen HJ

doi

10.1159/000280918

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

337-9

issue

6

eissn

0042-1138

issn

1423-0399

journal_volume

38

pub_type

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