Abstract:
:Background/Aims/Objectives: We have investigated the clinical and physiological effects of Transfer Capacitive Resistive Energy (TCARE) therapy on men with Peyronie's disease (PD). METHODS:Ninety-six men with PD have been randomized in a 2:1 ratio to receive 3 sessions of TCARE therapy or sham therapy. Pain, penile curvature and erectile function have been assessed before the first treatment and up to 9 months after the end of treatment, using the Visual Analogue Scale for the pain, a goniometer to measure the degree of curvature using at-home photography and an International Index of Erectile Function (IIEF-5) questionnaire. RESULTS:A significant pain reduction at the end of the treatment in 51 (79.6%) patients (p < 0.01) of the treated group was observed. No significant improvements in the sham group (p = 0.23) have been observed. No statistical differences in the degree of curvature have been observed in both groups. No statistical improvements have been observed in the IIEF-5 questionnaire. Adverse events have not been reported. CONCLUSION:This is, to our knowledge, the first randomized, single-blind, sham-controlled study that shows that TCARE has a positive short-term clinical effect on pain in patients with PD. The feasibility and tolerability of this treatment produce an attractive new therapeutic option for men with PD.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Pavone C,Romeo S,D'Amato F,Usala M,Letizia Mauro G,Caruana Gdoi
10.1159/000467396subject
Has Abstractpub_date
2017-01-01 00:00:00pages
77-83issue
1eissn
0042-1138issn
1423-0399pii
000467396journal_volume
99pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:To assess the role of primary open surgery versus the recommended combination approach (percutaneous and lithotripsy) to treat staghorn calculi in a developing country. PATIENTS AND METHODS:Available records (n = 91) of patients with staghorn managed during the last 4 years were retrieved. Patients were plac...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030456
更新日期:1999-01-01 00:00:00
abstract::The prevalence, pathogenesis and clinical aspects of bacterial infections of the female urinary tract are described and the efficacy of therapies used at present is discussed. Based on a retrospective compilation of data on 142 female patients with urinary tract infections, the pathogen spectrum is defined and the the...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281989
更新日期:1987-01-01 00:00:00
abstract:INTRODUCTION:Immunotherapy effectively treats advanced renal cell carcinoma in only a limited number of patients. However, the predicted prognosis for each patient in relation to immune status and response to immunotherapy remains problematic. We analyzed tumor-infiltrating lymphocyte (TIL) subsets to determine whether...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000064361
更新日期:2002-01-01 00:00:00
abstract::A 33-year-old male presented to the Chiba University Hospital with the main complaint of right flank pain. Bilateral vas deferens were not palpable. Hormonal examination revealed hypergonadotropic hypogonadism and cytogenetic studies a 47,XXY karyotype. The significance of the association of this karyotype with the ab...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281703
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:We investigated the status of erectile function and urinary continence after radical prostatectomy to investigate a possible relation between them and then determined whether the status of postoperative urinary continence affected erectile function. PATIENTS AND METHODS:Seventy-six patients who had no sym...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000078801
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:The German Research Activities on Natural Urologicals (GRANU) study was a randomized, partially blinded, placebo-controlled, parallel-group trial that investigated the efficacy of pumpkin seed in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH/LUTS). SUBJECTS AND METH...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000362903
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To assess the effect of neoadjuvant hormone treatment before radical prostatectomy on: tumor/prostate volume, prostate-specific antigen (PSA) and testosterone levels, surgical margin status and tumor stage, and the ease of surgery following treatment. METHODS:Patients with clinically localized prostatic car...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000077113
更新日期:2004-01-01 00:00:00
abstract::The purpose of this study is to report the safety and efficiency of laparoscopic varicocelectomy in 100 consecutive patients operated at a single teaching institution. There were three indications: (1) infertility associated with oligo-astheno-teratospermia (n = 52); (2) chronic dragging sensation of the left testicle...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282986
更新日期:1997-01-01 00:00:00
abstract:INTRODUCTION:There is increasing interest in evaluating the quality of life of patients with cortisol-producing adrenocortical adenoma (CPA). Our objective was to assess patient-reported health-related quality of life (HRQOL) in patients with CPA compared to non-CPA. METHODS:Between January 2012 and September 2015, a ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000508765
更新日期:2020-01-01 00:00:00
abstract::Adenosine triphosphate (ATP) and adenosine diphosphate (ADP) have been correlated with traditional semen parameters such as forward motility and sperm count. ATP and ADP were determined by a bioluminescence assay using the luciferin-luciferase reaction. Short boiling of the ejaculate was performed to inactivate phosph...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282361
更新日期:1992-01-01 00:00:00
abstract:INTRODUCTION:Urethral valves can be of enormous clinical importance. Both the prognosis for an affected fetus and the indication for a prenatal therapeutic intervention depend to a high degree on the accuracy of the prenatal diagnosis. PATIENTS AND METHODS:The sonographic findings and the results of the postnatal diag...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000081586
更新日期:2004-01-01 00:00:00
abstract::Ischemia, induced by atherosclerosis, is a common cause of disorders in the elderly. Bladder dysfunction in older people may be caused by detrusor ischemia. We compared blood flow to the bladder and detrusor function in vivo and in vitro in young (6-month-old) and aged (24-month-old) male Sprague-Dawley rats. In both ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030365
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to investigate the relationship among serum mean platelet volume (MPV) levels, benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS) and metabolic syndrome (MetS), and study the potential role of serum MPV levels in BPH/LUTS progression in an indirect manner. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000443313
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To assess our short-term experience with transurethral microwave thermotherapy (TUMT) for symptomatic benign prostatic hyperplasia (BPH). PATIENTS AND METHODS:From August 1993 through July 1994, in total 65 patients with symptomatic BPH were enrolled into this study. The patients' ages ranged from 56 to 95 yea...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章
doi:10.1159/000064846
更新日期:2000-01-01 00:00:00
abstract::Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000321908
更新日期:2011-01-01 00:00:00
abstract::Varicocele is one of the causes of male infertility. Treatment aims to improve the chance of conception despite lasting controversies about benefits of varicocele repair on fertility. Many techniques have been described for varicocele management including the antegrade scrotal sclerotherapy (ASS). Interestingly, ASS i...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000481831
更新日期:2018-01-01 00:00:00
abstract::Bladder tumors were staged preoperatively before and/or after M-VEC poly-chemotherapy using transrectal ultrasonography and magnetic resonance imaging in 46 patients. The resultant findings were each compared with histomorphologic results. The sensitivity of both methods compared with pathohistology was 88%. Using thi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282472
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:To report conservative and surgical strategies for treatment of mesh erosion after pelvic organ prolapse (POP) repair. METHODS:Between 1998 and 2008, 179 patients underwent integral pelvic floor reconstruction for advanced POP in our tertiary urogynecological unit. Patients' charts and follow-up data were en...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000324243
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:This open label, phase I clinical trial (NCT02945462) using 2 consecutive intracavernous autologous bone marrow-derived mesenchymal stem cells (BM-MSCs) for the first time in the treatment of diabetic patients with erectile dysfunction (ED). The primary outcome is to assess the safety and tolerability of int...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000492120
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Many epidemiological and experimental studies report a strong role of chemical carcinogens in the etiology of bladder cancer. However, involvement of trace elements in the tumorigenesis of transitional cell carcinoma of the bladder has been poorly investigated. The aim of this study was to examine the rela...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000341976
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:Renal cell carcinoma (RCC) forming tumor thrombus (TT) of vena cava (VC) is characterized by poor prognosis. Nevertheless, the outcome of patients after radical surgery varies. To date only limited data concerning prognostic biomarkers in this RCC subgroup are available. METHODS:Out of 159 patients with pT3b/c...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000497279
更新日期:2019-01-01 00:00:00
abstract::Urethral diverticula are pouches opening into the urethral canal that may be either acquired or congenital. Diverticula of the female urethra are fairly common. However, diverticula of the male urethra are relatively uncommon abnormalities. Clinical manifestation is frequently described with irritative and/or obstruct...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000346321
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:This present study was undertaken to determine the levels of malondialdehyde (MDA), nitric oxide (NO) and total antioxidant status (TAS) in testes of adolescent rats with experimental bilateral varicocele and to determine the effects of oxidative stress on testis produced by varicocele. METHODS:6-week-old, m...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000081596
更新日期:2004-01-01 00:00:00
abstract::We examined Southern blot analysis of genomic DNAs from 70 patients with sporadic renal cell carcinoma, using the human L-myc oncogene fragment as a hybridization probe. Our purpose was to study the relationship between the restriction fragment length polymorphism (RFLP) of the L-myc and the frequencies of metastasis....
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282261
更新日期:1991-01-01 00:00:00
abstract:INTRODUCTION:There are relatively few studies that compare the use of transrectal ultrasound (TRUS) to magnetic resonance imaging (MRI) to estimate the prostate volume. In this study, we compared the prostate volumes measured with MRI and TRUS with a surgical specimen volume. PATIENTS AND METHODS:Seventy-three patient...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000100836
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Prostate biopsy (PBx) techniques have changed significantly since the original Hodge's scheme, with an increase in the number and location of cores. These improvements have been realized in part because of the introduction of different local anaesthesia techniques. We critically analysed the literature discu...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000327827
更新日期:2011-01-01 00:00:00
abstract::We report the first case of aspergillus mycotic aneurysm as a sequel to concomitant prostatic and renal aspergillosis. The patient had undergone left nephrectomy and transurethral resection of prostate for aspergillus infection one year ago. He again presented with LUTS and backache and clinical examination showed vis...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000056561
更新日期:2001-01-01 00:00:00
abstract::During the past 10 years, buccal mucosa grafting for urethroplasty has gained widespread acceptance. In general the reported success rates are 80% and higher. Typical complications are recurrent strictures, fistula, and, especially when the technique of ventral onlay urethroplasty has been used, sacculations that are ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000096344
更新日期:2006-01-01 00:00:00
abstract::Clear cell adenocarcinoma arising in the lower urinary tract is unusual. We report a case of clear cell adenocarcinoma of the bladder in a 54-year-old male. Cystoscopic examination revealed a tumour arising from the dome of the urinary bladder. Histologically, the tumour was chiefly composed of tubulocystic and papill...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000071856
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:The study aimed to present our experience of surgical treatment for urorectal fistulas (URF) that develop after cancer surgery. MATERIALS AND METHODS:Fourteen patients with URF who were treated at our institution from 2005 through 2015 were retrospectively analyzed. Among these, 7 patients had previous su...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000457835
更新日期:2017-01-01 00:00:00