Abstract:
:Biopsies of 9 testicular tumors were examined for the presence of cytoplasmic receptor proteins for estrogens, progestins, androgens, and glucocorticoids. Using an arbitrary threshold value of 10 fmol/mg cytosol protein for a postive assay, only 1 of 9 tumors was estrogen-receptor positive. However, no receptor-specific 8S binding could be detected by low salt sucrose gradient centrifugation. 1 tumor was progesterone-receptor positive. No androgen receptors could be demonstrated. In contrast, 8 of 9 neoplasms contained significant quantities of glucocorticoid receptors exclusively sedimenting at 8S. Our findings suggest that androgens, estrogens, and progestins are unlikely to play a major role in the natural history of testicular tumors. The presence of glucocorticoid receptors might offer a chance for endocrine manipulation of the development and growth of these neoplasms by glucocorticoids.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Bojar H,Weissbach L,Petzinna D,Maar K,Staib Wdoi
10.1159/000281072subject
Has Abstractpub_date
1985-01-01 00:00:00pages
160-3issue
3eissn
0042-1138issn
1423-0399journal_volume
40pub_type
杂志文章abstract:OBJECTIVE:This randomized controlled study compared a novel transparent urinary tract simulator with the traditional opaque urinary tract simulator as an aid for efficiently teaching urological surgical procedures. METHODS:Senior medical students were tested on their understanding of urological theory before and after...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000375129
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:We aimed to evaluate the predictive factors in a holistic manner for ureterorenoscopy (URS) outcomes in proximal ureteral stones by a multicenter study. MATERIALS AND METHODS:The data of patients who underwent URS for proximal ureteral stones between the years 2015 and 2018 in eight centers were recorded ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000504790
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To assess MRI/Transrectal Ultrasound (TRUS) fusion three-dimensional model-guided targeted biopsy (3D-Tb) versus TRUS-guided systematic biopsy (Sb) in detecting overall and high-Gleason-score (≥7) prostate cancer (PCa). METHODS:Pubmed and Web of science were searched. Studies with men having a suspicious lesio...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000484144
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Cyclooxygenase-2 (COX-2) is a key enzyme involved in the production of prostaglandins and its inhibitors have been shown to induce apoptosis in a variety of cancer cells. We reasoned that combination treatment of renal cell carcinoma (RCC) cells with COX-2 inhibitors and anticancer agents may result in syner...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000288243
更新日期:2010-01-01 00:00:00
abstract::During 1986 and 1987, 47 patients with renal cell carcinoma were evaluated preoperatively with CT, angiography and MRI. The preoperative tumor stage (T), lymph node metastases and venous involvement determined with the three methods were compared to the operative and histopathological findings. For T stage, angiograph...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282219
更新日期:1991-01-01 00:00:00
abstract::Here we describe the clinical, radiologic, histopathological and immunohistochemical features of a rare spontaneous rupture of renal angiosarcoma detected in the left kidney of a 55-year-old male. Due to the rarity of this neoplasm (less than 15 cases have been reported), there is no unanimous consensus for therapy fo...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000048419
更新日期:2002-01-01 00:00:00
abstract:AIMS:This study was to identify factors that influence the early increase in the dose of intracavernous vasoactive agents to maintain erection for satisfactory intercourse and to elucidate when the dose increase would begin. METHODS:Seventy-nine patients using intracavernous pharmacotherapy with tri-mix (PGE(1), papav...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章
doi:10.1159/000064877
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To conduct a meta-analysis examining p53 expression as a potential risk factor in upper urinary tract urothelial carcinoma (UUT-UC) and to systematically review the available data. METHODS:A comprehensive literature review was performed from January 1991 to August 2012, using search engines such as PubMed, E...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000360227
更新日期:2015-01-01 00:00:00
abstract::15 patients with urinary infection were selected and analyzed in relation to infection in the vaginal and perianal areas. After treatment, 12 patients with urinary infection were cured, but bacterial organisms persisted in their vaginal and perianal areas. In spite of the persistence of the vaginal and perianal infect...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280207
更新日期:1978-01-01 00:00:00
abstract::Ninety-five patients with erectile dysfunction underwent standardized cavernosometry and cavernosography. In a first stage, the investigation was performed in each patient without and in a second stage with 60 mg papaverine injected intracavernously. A pathological maintenance flow rate between 20 and 120 ml/min decre...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282389
更新日期:1992-01-01 00:00:00
abstract::Testicular microlithiasis associated with seminoma was found in a 32-year-old infertile man. Gray-scale and color Doppler ultrasound findings are discussed and a brief review of the literature is presented. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282928
更新日期:1996-01-01 00:00:00
abstract::We examined Southern blot analysis of genomic DNAs from 70 patients with sporadic renal cell carcinoma, using the human L-myc oncogene fragment as a hybridization probe. Our purpose was to study the relationship between the restriction fragment length polymorphism (RFLP) of the L-myc and the frequencies of metastasis....
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282261
更新日期:1991-01-01 00:00:00
abstract::In 40 patients with urinary bladder tumours we compared the results of the immune profile, obtained by means of cutaneous tests with dinitrochlorobenzene (DNCB), and the infiltration of immunocompetent cells in the histological pattern after transurethral tumour resection. It was noted that the more the tumour had inf...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280798
更新日期:1982-01-01 00:00:00
abstract:INTRODUCTION:Silicone has been the standard prosthesis material for the last three decades but new materials are being searched because of the known disadvantages of silicone such as migration and high cost. We wanted to test in rats whether or not polymethylmethacrylate could be an alternative to silicone. MATERIALS ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000075277
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:Immunotherapy effectively treats advanced renal cell carcinoma in only a limited number of patients. However, the predicted prognosis for each patient in relation to immune status and response to immunotherapy remains problematic. We analyzed tumor-infiltrating lymphocyte (TIL) subsets to determine whether...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000064361
更新日期:2002-01-01 00:00:00
abstract::In unilateral kidney disease, it has been suggested that the ipsilateral state could be estimated by measuring contralateral kidney size; thus, a contralateral increase should reflect an ipsilateral impairment and vice versa. This could easily be performed using ultrasound. In our experiments with partial obstruction ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282898
更新日期:1996-01-01 00:00:00
abstract::We report the case of a woman who presented with obstruction and urosepsis of her left kidney secondary to small cystine calculi. The calculi could not be seen on initial plain abdominal X-ray. However, following percutaneous nephrostogram the calculi became more radio-dense and visible on later X-rays. Experimental e...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030375
更新日期:1999-01-01 00:00:00
abstract::Ectopia of the vas deferens (EVD) combined with agenesis of the seminal vesicle, is a rare congenital abnormality. We describe a case of EVD with agenesis of the ipsilateral seminal vesicle, presenting with pneumaturia and frequent urinary tract infection. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000070144
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:Splenectomy had been previously performed in ABO-incompatible kidney transplantation to reduce the B cell pool. However, studies have shown that patients undergoing splenectomy may have a lifelong susceptibility to infection and mortality. Splenectomy may affect the incidence of cytomegalovirus (CMV) disea...
journal_title:Urologia internationalis
pub_type:
doi:10.1159/000504862
更新日期:2020-01-01 00:00:00
abstract::A 63-year-old man with primary malignant lymphoma of the prostate is presented. The patient underwent total cystoprostatectomy and ileal conduit construction. The specimen revealed malignant lymphoma, diffuse small cleaved cell of the gland. Three months after the operation, local recurrence and enlarged lymph node de...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282216
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:There is a considerable lack of consensus regarding indications and long-term efficacy of the many techniques for treating urinary stress incontinence. We report the long-term results of a modified pubovaginal sling procedure. METHODS:From 1989 to 1998, 129 consecutive patients underwent a pubovaginal sling...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000077685
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:International guidelines are ambivalent regarding the recommendations for the management of clinical stage 1 (CS1) seminoma. PATIENTS AND METHODS:During 2008-2013, 1,050 patients with seminoma CS1 were prospectively registered with regard to assessing management modality (radiotherapy, carboplatin, survei...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000443214
更新日期:2016-01-01 00:00:00
abstract:AIM:To compare the efficacy and safety of silodosin versus tamsulosin as medical expulsive therapy for stones of lower-third ureter in children. PATIENTS AND METHODS:This prospective single-blind placebo-controlled randomized study included 167 pediatric patients who presented with distal ureteric stone (DUS) less tha...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000513074
更新日期:2021-02-01 00:00:00
abstract:PURPOSE:To compare the safety and efficacy of standard-tract combined with mini-tract to single standard-tract in percutaneous nephrolithotomy (PCNL) for renal staghorn calculi. METHODS:The records of 216 patients with staghorn calculi (110 (50.9%) had complete and 106 (49.1%) had partial) who received PCNL were revie...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000354427
更新日期:2014-01-01 00:00:00
abstract::In 153 patients with verified neoplasias of the genitourinary tract, urinary neopterin excretion was monitored under different conditions. As control, urinary neopterin values were taken from 208 male and 209 female volunteers. Neopterin excretion was measured by high performance liquid chromatography. Patients with e...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281071
更新日期:1985-01-01 00:00:00
abstract:INTRODUCTION:Urachal cancer (UrC) is a rare but aggressive cancer. Due to its low incidence, structured epidemiological data have only rarely been reported. To date, no valid data on UrC are available for the German population. METHODS:Data on incidence and relative 5-year survival of urachal lesions (ICD-10: C67.7) w...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000509481
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:Basic science studies of ureteral physiology and pathophysiology are commonly performed on animal ureters due to several limitations associated with human ureteral sampling. In this work we question whether animal ureters are good replicas of human ureteral behavior for pharmacological studies. MATERIALS AN...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000358601
更新日期:2015-01-01 00:00:00
abstract::During infancy, the renal parenchyma and pelvicalyceal system are relatively fragile. Therefore, percutaneous nephrolithotomy for the management of renal stones in this age group is a challenging procedure for urologists. Herein, we present the uneventful management of bilateral renal stones using micropercutaneous ne...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000360645
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:No established technique for locating solitary carcinoma in situ (CIS) of the urinary bladder or CIS accompanying bladder cancer has been determined. Here we investigated whether the location of CIS of the urinary bladder can be macroscopically ascertained by instilling pirarubicin hydrochloride (THP) into...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000083555
更新日期:2005-01-01 00:00:00
abstract::We present a 17-year-old patient with a right testicular dislocation. In this case, dislocated testis had been considered as hematoma and therefore remained untreated for 4 months. The patient underwent right orchiopexy 4 months after the injury. Intraoperative testicular biopsy revealed impaired spermatogenesis and e...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282830
更新日期:1996-01-01 00:00:00