Abstract:
AIM:To compare the efficacy and safety of silodosin versus tamsulosin as medical expulsive therapy for stones of lower-third ureter in children. PATIENTS AND METHODS:This prospective single-blind placebo-controlled randomized study included 167 pediatric patients who presented with distal ureteric stone (DUS) less than 1 cm. Patients were randomized into 3 groups; group I received silodosin 4 mg once daily, and group II received tamsulosin 0.4 mg while those in group III had placebo. The side effects of the used drugs, both rate and time of stone expulsion, and number of pain episodes were compared among the study groups for a maximum of 4 weeks. RESULTS:Follow-up data of our patients after treatment revealed that the stone expulsion rate was significantly higher and the time to stone expulsion was significantly shorter in group I (89.3%, 12.4 ± 2.3 days) and group II (74.5%, 16.2 ± 4.2 days) compared to group III (51.8%, 21.2 ± 5.6). However, a statistically significant difference between silodosin and tamsulosin groups in favor of the former one was reported regarding the 2 studied items. Meanwhile, pain episodes requiring analgesia were statistically fewer in group I and II in contrast to placebo group. Adverse events were comparable among all groups. CONCLUSION:Silodosin provides significantly better stone expulsion rate and shorter expulsion time than tamsulosin for treatment of DUS. Both medications showed good safety profiles in children. However, further studies are required on a larger scale to confirm our results. Assessment of drug safety on younger age-group is still needed.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Soliman MG,El-Gamal O,El-Gamal S,Abdel Raheem A,Abou-Ramadan A,El-Abd Adoi
10.1159/000513074subject
Has Abstractpub_date
2021-02-01 00:00:00pages
1-6eissn
0042-1138issn
1423-0399pii
000513074pub_type
杂志文章abstract::A case of spontaneous, partial, unilateral thrombosis of the corpus cavernosum is described. A 35-year-old white male presented with a painful mass in the perineum without priapism. Diagnostic evaluation with sonography and magnetic resonance imaging revealed a thrombosis in the left posterior corporal body. Treatment...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030246
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:We report our experience with the use of povidone iodine instillation into the renal pelvis for the treatment of chyluria. MATERIALS AND METHODS:From August 2006 to November 2008, 26 patients with chyluria were treated. There were 18 males and 8 females ranging from 24-55 years of age. Cystoscopic localization...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000288233
更新日期:2010-01-01 00:00:00
abstract::The measurement of sodium and water loss after relieve of the obstruction shows that the obstructive nephropathy originates in three pathogenetic mechanisms. (1) Acute complete bilateral ureteric obstruction causes tubular atrophy, prevents both resorption and glomerular filtration, reduces the renal blood flow and in...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280270
更新日期:1979-01-01 00:00:00
abstract::The results of clam ileocystoplasty in 32 patients were evaluated. Nineteen patients had a neuropathic (group N) and 13 a nonneuropathic disease (group NN). Mean follow-up was 75 months; 62 months for group N and 95 months for group NN. Mean age was 38 years. Postoperative complications and some quality-of-life parame...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282577
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to evaluate prognostic factors for patients with upper urinary tract urothelial carcinoma (UUT-UC) after nephroureterectomy and to seek a better way of finding more favorable clinical results for these patients. PATIENTS AND METHODS:We retrospectively reviewed the medical rec...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000335274
更新日期:2012-01-01 00:00:00
abstract::Sacrocolpopexy, a surgical technique with a low morbidity rate, is a valid procedure for repairing vaginal vault prolapse. To our knowledge, only 1 case of rectum erosion after open sacrocolpopexy has been reported in the literature, and there is no record of any such incident after laparoscopic sacrocolpopexy. We rep...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000353421
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Endorectal coil MRI (endoMRI) of the prostate is useful to evaluate tumor localization. There is little evidence on patient characteristics affecting its diagnostic performance. We evaluate the influence of clinical and histological parameters on the accuracy of endoMRI. METHODS:Sixty-nine patients with pro...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000324098
更新日期:2011-01-01 00:00:00
abstract::In an acute rat model (in vivo) spontaneous rhythmic bladder contractions were induced by ligation of the urethra. In addition single bladder contractions were recorded during neurostimulation of the pelvic nerve. Spontaneous and electrically induced bladder contractions were sensitive to papaverine and isoprenaline i...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282425
更新日期:1992-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1984-01-01 00:00:00
abstract:INTRODUCTION:The aims of this study were to establish the prevalence of enuresis, to determine accompanying factors, and to identify common methods in the management of enuresis in Turkish children aged between 6 and 11 years living in eastern Anatolia. METHODS:The parents of 3,527 schoolchildren aged between 6 and 11...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000079696
更新日期:2004-01-01 00:00:00
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journal_title:Urologia internationalis
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journal_title:Urologia internationalis
pub_type: 杂志文章
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000345630
更新日期:2013-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280034
更新日期:1976-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000056561
更新日期:2001-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280303
更新日期:1980-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1996-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
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journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
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更新日期:2014-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000111736
更新日期:2008-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000443799
更新日期:2016-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280073
更新日期:1976-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000335432
更新日期:2012-01-01 00:00:00
abstract::Amputation of the penis is by no means the quickest and least invasive of the surgical methods of treating penis carcinoma. Radiation therapy has the advantage of preserving the integrity of the penis and does not render a later operation of the penis impossible. Regional lymph node metastases should be removed surgic...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280899
更新日期:1983-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
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journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000350508
更新日期:2013-01-01 00:00:00
abstract::Sperm-specific glyceraldehyde 3-phosphate dehydrogenase (GAPDS) originates from spermatogenic cells of the human testis. A strong staining of GAPDS was detected in epididymal epithelium, especially in principal cells and basal cells of the epithelium. GAPDS also bound to the fibrous sheet of the sperm tail and inhibit...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000345629
更新日期:2013-01-01 00:00:00