The efficacy of prazosin HCl in the treatment of urinary flow obstruction due to prostatic hypertrophy.

Abstract:

:Prazosin HCl was administered to 20 patients with urinary obstructions associated with prostatic hypertrophy. Significant reductions were recorded in the nighttime and the mean 24-hour urination frequencies. Patient-assessed symptoms diminished significantly, and uroflowmetry revealed significant increases in average and maximum urine flow rates. Residual urine volume decreased, the residual urine ratio declined, and bladder compliance tended to increase. The prazosin HCl therapy produced no significant effects on blood pressure or pulse rate, and no side effects appeared. The therapy was judged to be 'extremely beneficial' in 10%, 'beneficial' or better in 50%, and 'marginally beneficial' or better in 85% of all the patients.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Kondo A,Gotoh M,Saito M,Takita T,Kobayashi M,Otani T,Ito K

doi

10.1159/000282023

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

4-17

eissn

0042-1138

issn

1423-0399

journal_volume

45 Suppl 1

pub_type

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