Successful management of metastatic urothelial carcinoma with gemcitabine and Paclitaxel chemotherapy in a hemodialysis patient.

Abstract:

:This is the first report of urothelial carcinoma (UC) in a hemodialysis (HD) patient treated with almost the same doses of gemcitabine and paclitaxel (GP) as those administered to patients with normal renal function. There have been some reports of UC treated with cisplatin-based chemotherapy in HD patients. However, there have only been a few reports of UC treated with GP in HD patients. Furthermore, to our knowledge, there has not been any report of UC in a HD patient treated with almost the same doses of GP as those in patients with normal renal function. Following cystectomy for bladder cancer, a 73-year-old woman undergoing HD developed lung metastasis and received combination chemotherapy with almost the same doses of GP as those in patients with normal renal function. After three cycles were completed, metastatic tumors disappeared and there has not been any recurrence or metastasis for 1 year to date. Furthermore, there were no grade 3 or 4 adverse effects during this treatment.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Ide H,Satou A,Hoshino K,Yasumizu Y,Uchida Y,Tasaka Y,Masuda T

doi

10.1159/000327511

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

245-7

issue

2

eissn

0042-1138

issn

1423-0399

pii

000327511

journal_volume

87

pub_type

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