解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:In recent years, intraoperative radiotherapy (IORT) has been increasingly used for the treatment of rectal cancer. However, the efficacy and safety of IORT for the treatment of rectal cancer are still controversial. AIM:To evaluate the value of IORT for patients with rectal cancer. METHODS:We searched PubM...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v13.i1.69
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:Due to the special clinical features and biologic characteristics of adolescent and young adult (AYA) cancers, AYA cancers are different from cancers in children and elderly individuals. However, there are few reports on AYA hepatocellular carcinoma (HCC). AIM:To investigate the overall survival (OS) of AYA...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v12.i12.1394
更新日期:2020-12-15 00:00:00
abstract:BACKGROUND:Recent studies have proved the important role of many oncogenic long non-coding RNAs (lncRNAs) in the progression of pancreatic cancer, but little is known about the mechanisms of tumor suppression in pancreatic cancer. AIM:To evaluate the function of tumor suppressor lncRNA C9orf139 in pancreatic cancer pr...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v12.i11.1272
更新日期:2020-11-15 00:00:00
abstract:BACKGROUND:Kinesin super family 23 (KIF23) is a member of the KIF family, and it plays an important role in mitosis and cytokinesis. Loss of expression can cause mitotic arrest. The Oncomine database is one of the largest oncogene chip databases in the world, and is an integrated data mining platform for cancer gene in...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v12.i10.1104
更新日期:2020-10-15 00:00:00
abstract::5-flurouracil (5-FU)-based chemotherapy is the main pharmacological therapy for advanced colorectal cancer (CRC). Despite significant progress in the treatment of CRC during the last decades, 5-FU drug resistance remains the most important cause of failure in CRC therapy. Resistance to 5-FU is a complex and multistep ...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v12.i9.942
更新日期:2020-09-15 00:00:00
abstract:BACKGROUND:Breast metastases from colorectal cancer (CRC) are very uncommon. There is no unanimous consensus regarding the best treatment for this rare condition, and management is, especially in elderly patients, limited to diagnosis and palliative care. Capecitabine, an oral fluoropyrimidine derivative, might be help...
journal_title:World journal of gastrointestinal oncology
pub_type:
doi:10.4251/wjgo.v12.i9.1073
更新日期:2020-09-15 00:00:00
abstract::Gastrointestinal neuroendocrine tumors are rare slow-growing tumors with distinct histological, biological, and clinical characteristics that have increased in incidence and prevalence within the last few decades. They contain chromogranin A, synaptophysin and neuron-specific enolase which are necessary for making a d...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v12.i8.791
更新日期:2020-08-15 00:00:00
abstract:BACKGROUND:Overexpression of SQSTM1 (sequestosome 1, P62) and nuclear factor-κB (NF-κB) plays an important role in the invasion and metastasis of a variety of malignant tumors. AIM:To explore the expression of P62 and NF-κB in pancreatic cancer and their relationship with clinicopathological features. METHODS:The exp...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v12.i7.719
更新日期:2020-07-15 00:00:00
abstract:BACKGROUND:Esophagectomy is a pivotal curative modality for localized esophageal or esophagogastric junction cancer (EC or EJC). Postoperative anastomotic leakage (AL) remains problematic. The use of fibrin sealant (FS) may improve the strength of esophageal anastomosis and reduce the incidence of AL. AIM:To assess th...
journal_title:World journal of gastrointestinal oncology
pub_type: 临床试验
doi:10.4251/wjgo.v12.i6.651
更新日期:2020-06-15 00:00:00
abstract:BACKGROUND:Rectal cancer (RC) is one of the most common diagnosed cancers, and one of the major causes of cancer-related death nowadays. Majority of the current guidelines rely on TNM classification regarding therapy regiments, however recent studies suggest that additional histopathological findings could affect the d...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v12.i5.592
更新日期:2020-05-15 00:00:00
abstract:BACKGROUND:Reports in the field of robotic surgery for rectal cancer are increasing year by year. However, most of these studies enroll patients at a relatively early stage and have small sample sizes. In fact, studies only on patients with locally advanced rectal cancer (LARC) and with relatively large sample sizes ar...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v12.i4.424
更新日期:2020-04-15 00:00:00
abstract:BACKGROUND:Regorafenib is an oral small-molecule multikinase inhibitor approved in third or later line of treatment for patients with metastatic colorectal cancer (mCRC). Regorafenib has shown significant benefits in overall survival and progression free survival in two phase III trials compared to placebo in patients ...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v12.i3.301
更新日期:2020-03-15 00:00:00
abstract:BACKGROUND:Brain metastasis (BM) from colorectal cancer (CRC) is rarely encountered clinically, and its prognosis has not been fully evaluated. AIM:To construct a scoring system and accurately predict the survival of patients with synchronous BM at diagnosis of CRC. METHODS:A retrospective study of 371 patients with ...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v12.i2.195
更新日期:2020-02-15 00:00:00
abstract::Gastrointestinal (GI) cancer has a high tumor incidence and mortality rate worldwide. Despite significant improvements in radiotherapy, chemotherapy, and targeted therapy for GI cancer over the last decade, GI cancer is characterized by high recurrence rates and a dismal prognosis. There is an urgent need for new diag...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v12.i1.1
更新日期:2020-01-15 00:00:00
abstract:BACKGROUND:It has been recognized for a long time that gastric cancer behavior and outcomes might be different between patients living in Asian countries vs patients living in Western countries. It is not clear if these differences would persist between patients of Asian ancestry and patients of other racial subgroups ...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v11.i12.1151
更新日期:2019-12-15 00:00:00
abstract:BACKGROUND:Toll-like receptors (TLRs) are the first line of host defense, and are involved in Helicobacter pylori (H. pylori) recognition and activation of both inflammatory and carcinogenic processes. The presence of single nucleotide polymorphisms (SNPs) in genes that activate the immune response may modulate the ris...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v11.i11.998
更新日期:2019-11-15 00:00:00
abstract::Over the past ten years, sorafenib, a multikinase inhibitor, has been the standard of care for patients with unresectable hepatocellular carcinoma (HCC) and well-preserved liver function. Recently, lenvatinib, a different multikinase inhibitor, was shown to be non-inferior to sorafenib, in terms of survival, while all...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v11.i10.788
更新日期:2019-10-15 00:00:00
abstract:BACKGROUND:Epstein-Barr virus (EBV)-associated carcinoma is a gastric cancer subtype with a morphology characterized by gastric carcinoma with lymphoid stroma (GCLS). Clinicopathological studies have indicated a better prognosis for GCLS than for common gastric carcinomas. Some previous cases of early gastric cancer as...
journal_title:World journal of gastrointestinal oncology
pub_type:
doi:10.4251/wjgo.v11.i10.925
更新日期:2019-10-15 00:00:00
abstract:BACKGROUND:Bile duct cancer constitutes gallbladder cancer (GBC), intrahepatic cholangiocarcinoma (ICA), and extrahepatic cholangiocarcinoma (ECA). These three entities show morphological and immunohistochemical resemblance so that it is difficult to differentiate between primary ICA and liver metastasis of GBC, which ...
journal_title:World journal of gastrointestinal oncology
pub_type:
doi:10.4251/wjgo.v11.i9.761
更新日期:2019-09-15 00:00:00
abstract::Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the second leading cause of cancer mortality worldwide. The cornerstone to improving the prognosis of HCC patients has been the control of loco-regional disease progression and the lesser toxicities of local treatment. Although radiotherapy has not...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v11.i8.579
更新日期:2019-08-15 00:00:00
abstract::While the incidence and mortality of gastric cancer (GC) have declined due to public health programs, it remains the third deadliest cancer worldwide. For patients with early disease, innovative endoscopic and complex surgical techniques have improved survival. However, for patients with advanced disease, there are li...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v11.i7.509
更新日期:2019-07-15 00:00:00
abstract:BACKGROUND:Radical D2 lymphadenectomy for advanced gastric cancer as a standard procedure has gained global consensus. Mounting studies have shown that the number of lymph nodes dissection directly affects the prognosis and recurrence of gastric cancer. Our previous study showed that there was no obvious lymph node aro...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v11.i6.499
更新日期:2019-06-15 00:00:00
abstract:BACKGROUND:Pathological manifestations of hepatic tumours are often associated with prognosis. Although surgical specimens (SS) can provide more information, currently, pre-treatment needle core biopsy (NCB) is increasingly showing important value in understanding the nature of liver tumors and even in diagnosis and tr...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v11.i5.404
更新日期:2019-05-15 00:00:00
abstract:BACKGROUND:Long non-coding RNAs (lncRNAs) are a kind of single-stranded RNA of more than 200 nucleotides in length and have no protein-coding function. Amounting studies have indicated that lncRNAs could play a vital role in the initiation and development of cancers, including gastric cancer (GC). Considering the cruci...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v11.i2.139
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:Neoadjuvant chemotherapy has been applied worldwide to improve the survival of patients with gastric adenocarcinoma (GAC). The evaluation of histological regression in primary tumors is valuable for predicting prognosis. However, the prognostic effect of regression change in lymph nodes (LNs) remains unclear...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v11.i1.48
更新日期:2019-01-15 00:00:00
abstract::Despite significant advances in imaging techniques, the incidence of colorectal cancer has been increasing in recent years, with many cases still being diagnosed in advanced stages. Early detection and accurate staging remain the main factors that lead to a decrease in the cost and invasiveness of the curative techniq...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v10.i12.465
更新日期:2018-12-15 00:00:00
abstract::Laparoscopic and endoscopic cooperative surgery (LECS) is a surgical technique that combines laparoscopic partial gastrectomy and endoscopic submucosal dissection. LECS requires close collaboration between skilled laparoscopic surgeons and experienced endoscopists. For successful LECS, experience alone is not sufficie...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v10.i11.381
更新日期:2018-11-15 00:00:00
abstract::Peritoneal carcinomatosis (PC) from gastric cancer has traditionally been considered a terminal progression of the disease and is associated with poor survival outcomes. Positive peritoneal cytology similarly worsens the survival of patients with gastric cancer and treatment options for these patients have been limite...
journal_title:World journal of gastrointestinal oncology
pub_type: 社论
doi:10.4251/wjgo.v10.i10.282
更新日期:2018-10-15 00:00:00
abstract::Colorectal carcinogenesis (CRC) imposes a major health burden in developing countries. It is the third major cause of cancer deaths. Despite several treatment strategies, novel drugs are warranted to reduce the severity of this disease. Adenomatous polyps in the colon are the major culprits in CRC and found in 45% of ...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v10.i9.244
更新日期:2018-09-15 00:00:00
abstract::Hepatocellular carcinoma (HCC) is the fifth leading cause of cancer mortality in the United States and the second leading cause of cancer mortality worldwide. Sorafenib is the only food and drug administration (FDA) approved as first line systemic treatment in HCC. Regorafenib and nivolumab are the only FDA approved s...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v10.i5.108
更新日期:2018-05-15 00:00:00
abstract::Solid pseudopapillary neoplasm (SPN), also known as Gruber-Frantz tumor, is a rare form of neoplasm that almost exclusively occurs in the pancreas and in young females. While the potential of malignancy is low for SPN, these tumors can mimic other diseases and require a meticulous investigation and a standard treatmen...
journal_title:World journal of gastrointestinal oncology
pub_type:
doi:10.4251/wjgo.v9.i12.497
更新日期:2017-12-15 00:00:00
abstract::Primary non-Hodgkin lymphomas in the esophagus are rare. Tracheoesophageal fistulas mainly arise from solid esophageal carcinoma or mediastinal malignancies. Our patient presented with cough, dysphagia and weight loss, and upon initial computed tomography imaging and esophagogastroduodenoscopy, a malignant mass in the...
journal_title:World journal of gastrointestinal oncology
pub_type:
doi:10.4251/wjgo.v9.i10.431
更新日期:2017-10-15 00:00:00
abstract:AIM:To study tumor response, and tolerability of arterially directed embolic therapy (ADET) with polyethylene glycol embolics loaded with irinotecan for the treatment of colorectal cancer liver metastases (CRC-LM). Secondary objectives were to monitor quality of life, time to progression and survival of patients. METH...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v9.i9.379
更新日期:2017-09-15 00:00:00
abstract::Cholangiocarcinoma (CCA) is a rare cancer arising from the biliary tree with a poor prognosis and limited therapeutic options. Recent large scale molecular characterisation studies have identified recurrent genetic alterations in CCA which may be amenable to therapeutic targeting. In this review we explore the genomic...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v9.i7.268
更新日期:2017-07-15 00:00:00
abstract:AIM:To correct the misclassification in registered gastric cancer incidence across Iranian provinces in cancer registry data. METHODS:Gastric cancer data is extracted from Iranian annual of national cancer registration report 2008. A Bayesian method with beta prior is implemented to estimate the rate of misclassificat...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v9.i2.87
更新日期:2017-02-15 00:00:00
abstract::It is well established that colorectal cancer develops from a series of precursor epithelial polyps, including tubular adenomas, villous/tubulovillous adenomas (VA/TVA), sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA). Of these, TSAs are least common and account for only 5% of all serrated poly...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v8.i12.805
更新日期:2016-12-15 00:00:00
abstract::Colorectal cancer is the second leading cause of death from cancer among adults. The disease begins as a benign adenomatous polyp, which develops into an advanced adenoma with high-grade dysplasia and then progresses to an invasive cancer. Appropriate apoptotic signaling is fundamentally important to preserve a health...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v8.i8.583
更新日期:2016-08-15 00:00:00
abstract::Adenocarcinoma of small intestines (SBA) is a relatively rare malignancy with poor outcomes due to delayed diagnosis. Fifty percent of patients have metastases on presentation and therefore early detection and treatment offers the best long term outcomes. Certain genetic polyposis syndromes and familial diseases are a...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v8.i6.509
更新日期:2016-06-15 00:00:00
abstract::Surgical therapy for ulcerative colitis (UC) depends on the medical therapy administered for the patient's condition. UC is a benign disease. However, it has been reported that the rare cases of cancer in UC patients are increasing, and such cases have a worse prognosis. Recently, surgical therapy has greatly changed,...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v8.i4.351
更新日期:2016-04-15 00:00:00
abstract::Surgery remains the only chance of cure for pancreatic cancer, but only 15%-25% of patients present with resectable disease at the time of primary diagnosis. Important goals in clinical research must therefore be to allow early detection with suitable diagnostic procedures, to further broaden operation techniques and ...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
doi:10.4251/wjgo.v8.i3.248
更新日期:2016-03-15 00:00:00