Hypofractionated particle beam therapy for hepatocellular carcinoma-a brief review of clinical effectiveness.

abstract：:Most patients treated with curative intent for colorectal cancer (CRC) are included in a follow-up program involving periodic evaluations. The survival benefits of a follow-up program are well delineated, and previous meta-analyses have suggested an overall survival improvement of 5%-10% by intensive follow-up. Howeve...

journal_title：World journal of gastrointestinal oncology

authors： Augestad KM,Rose J,Crawshaw B,Cooper G,Delaney C

更新日期：2014-05-15 00:00:00

abstract：:Digestive endoscopy is currently the main diagnostic procedure for investigation of the digestive tract when a digestive disease is suspected. The use of computers and electronic medical records for the management of endoscopic data are an important key to improving endoscopy unit efficiency and productivity. This tec...

journal_title：World journal of gastrointestinal oncology

authors： Maserat E,Safdari R,Maserat E,Zali MR

更新日期：2012-04-15 00:00:00

abstract：:Over the past ten years, sorafenib, a multikinase inhibitor, has been the standard of care for patients with unresectable hepatocellular carcinoma (HCC) and well-preserved liver function. Recently, lenvatinib, a different multikinase inhibitor, was shown to be non-inferior to sorafenib, in terms of survival, while all...

journal_title：World journal of gastrointestinal oncology

authors： Personeni N,Pressiani T,Bozzarelli S,Rimassa L

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Epstein-Barr virus (EBV)-associated carcinoma is a gastric cancer subtype with a morphology characterized by gastric carcinoma with lymphoid stroma (GCLS). Clinicopathological studies have indicated a better prognosis for GCLS than for common gastric carcinomas. Some previous cases of early gastric cancer as...

journal_title：World journal of gastrointestinal oncology

authors： Kobayashi Y,Kunogi T,Tanabe H,Murakami Y,Iwama T,Sasaki T,Takahashi K,Ando K,Nomura Y,Ueno N,Kashima S,Moriichi K,Takei H,Fujiya M,Okumura T

更新日期：2019-10-15 00:00:00

abstract：:Low rectal cancer is traditionally treated by abdominoperineal resection. In recent years, several new techniques for the treatment of very low rectal cancer patients aiming to preserve the gastrointestinal continuity and to improve both the oncological as well as the functional outcomes, have been emerged. Literature...

journal_title：World journal of gastrointestinal oncology

authors： Dimitriou N,Michail O,Moris D,Griniatsos J

更新日期：2015-07-15 00:00:00

abstract：:Pancreatic surgery for malignancy is recognized as challenging for the surgeons and risky for the patients due to consistent perioperative morbidity and mortality. Furthermore, the oncological long-term results are largely disappointing, even for those patients who experience an uneventfully hospital stay. Nevertheles...

journal_title：World journal of gastrointestinal oncology

authors： Bencini L,Annecchiarico M,Farsi M,Bartolini I,Mirasolo V,Guerra F,Coratti A

更新日期：2015-12-15 00:00:00

abstract：:Primary non-Hodgkin lymphomas in the esophagus are rare. Tracheoesophageal fistulas mainly arise from solid esophageal carcinoma or mediastinal malignancies. Our patient presented with cough, dysphagia and weight loss, and upon initial computed tomography imaging and esophagogastroduodenoscopy, a malignant mass in the...

journal_title：World journal of gastrointestinal oncology

authors： Teerakanok J,DeWitt JP,Juarez E,Thein KZ,Warraich I

更新日期：2017-10-15 00:00:00

abstract：:Non-neoplastic tumor-like lesions in the pancreas are uncommon. Here, we present a case of multiple solid pancreatic hamartomas in a 78-year-old Japanese woman. Her computed tomography revealed a pancreatic mass, measuring 1.8 cm in maximum diameter. However, no symptoms were found. She was not an alcoholic and had no...

journal_title：World journal of gastrointestinal oncology

authors： Kawakami F,Shimizu M,Yamaguchi H,Hara S,Matsumoto I,Ku Y,Itoh T

更新日期：2012-09-15 00:00:00

abstract：:It is well established that colorectal cancer develops from a series of precursor epithelial polyps, including tubular adenomas, villous/tubulovillous adenomas (VA/TVA), sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA). Of these, TSAs are least common and account for only 5% of all serrated poly...

journal_title：World journal of gastrointestinal oncology

authors： Kalimuthu SN,Chelliah A,Chetty R

更新日期：2016-12-15 00:00:00

abstract：BACKGROUND:Due to the special clinical features and biologic characteristics of adolescent and young adult (AYA) cancers, AYA cancers are different from cancers in children and elderly individuals. However, there are few reports on AYA hepatocellular carcinoma (HCC). AIM:To investigate the overall survival (OS) of AYA...

journal_title：World journal of gastrointestinal oncology

authors： Ren J,Tong YM,Cui RX,Wang Z,Li QL,Liu W,Qu K,Zhang JY,Liu C,Wan Y

更新日期：2020-12-15 00:00:00

abstract：AIM:To identify genetic polymorphisms in the promoter region of the human base excision repair gene NEIL1 in gastric cancer patients. METHODS:The NEIL1 promoter region in DNA from 80 Japanese patients with gastric cancer was searched for genetic polymorphisms by polymerase chain reaction-single-strand conformation pol...

journal_title：World journal of gastrointestinal oncology

authors： Goto M,Shinmura K,Tao H,Tsugane S,Sugimura H

更新日期：2010-02-15 00:00:00

abstract：:Surgical therapy for ulcerative colitis (UC) depends on the medical therapy administered for the patient's condition. UC is a benign disease. However, it has been reported that the rare cases of cancer in UC patients are increasing, and such cases have a worse prognosis. Recently, surgical therapy has greatly changed,...

journal_title：World journal of gastrointestinal oncology

authors： Kinugasa T,Akagi Y

更新日期：2016-04-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a highly malignant tumor and extrahepatic metastasis is not rare. The most common organ of HCC metastasis is lung, followed by bone and adrenal gland. To the best of our knowledge, isolated pancreatic metastasis of HCC that developed after curative resection has not been described pre...

journal_title：World journal of gastrointestinal oncology

authors： Woo SM,Park JW,Han SS,Choi JI,Lee WJ,Park SJ,Hong EK,Kim CM

更新日期：2010-04-15 00:00:00

abstract：BACKGROUND:Toll-like receptors (TLRs) are the first line of host defense, and are involved in Helicobacter pylori (H. pylori) recognition and activation of both inflammatory and carcinogenic processes. The presence of single nucleotide polymorphisms (SNPs) in genes that activate the immune response may modulate the ris...

journal_title：World journal of gastrointestinal oncology

authors： Susi MD,Lourenço Caroline M,Rasmussen LT,Payão SLM,Rossi AFT,Silva AE,de Oliveira-Cucolo JG

更新日期：2019-11-15 00:00:00

abstract：:Deficiencies in DNA repair due to inherited germ-line mutations in DNA repair genes cause increased risk of gastrointestinal (GI) cancer. In sporadic GI cancers, mutations in DNA repair genes are relatively rare. However, epigenetic alterations that reduce expression of DNA repair genes are frequent in sporadic GI can...

journal_title：World journal of gastrointestinal oncology

authors： Bernstein C,Bernstein H

更新日期：2015-05-15 00:00:00

abstract：AIM:To study tumor response, and tolerability of arterially directed embolic therapy (ADET) with polyethylene glycol embolics loaded with irinotecan for the treatment of colorectal cancer liver metastases (CRC-LM). Secondary objectives were to monitor quality of life, time to progression and survival of patients. METH...

journal_title：World journal of gastrointestinal oncology

authors： Fiorentini G,Carandina R,Sarti D,Nardella M,Zoras O,Guadagni S,Inchingolo R,Nestola M,Felicioli A,Barnes Navarro D,Munoz Gomez F,Aliberti C

更新日期：2017-09-15 00:00:00

abstract：:5-flurouracil (5-FU)-based chemotherapy is the main pharmacological therapy for advanced colorectal cancer (CRC). Despite significant progress in the treatment of CRC during the last decades, 5-FU drug resistance remains the most important cause of failure in CRC therapy. Resistance to 5-FU is a complex and multistep ...

journal_title：World journal of gastrointestinal oncology

authors： Sabeti Aghabozorgi A,Moradi Sarabi M,Jafarzadeh-Esfehani R,Koochakkhani S,Hassanzadeh M,Kavousipour S,Eftekhar E

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Radical D2 lymphadenectomy for advanced gastric cancer as a standard procedure has gained global consensus. Mounting studies have shown that the number of lymph nodes dissection directly affects the prognosis and recurrence of gastric cancer. Our previous study showed that there was no obvious lymph node aro...

journal_title：World journal of gastrointestinal oncology

authors： Mu GC,Huang Y,Liu ZM,Chen ZB,Wu XH,Qin XG,Zeng YJ

更新日期：2019-06-15 00:00:00

abstract：BACKGROUND:Kinesin super family 23 (KIF23) is a member of the KIF family, and it plays an important role in mitosis and cytokinesis. Loss of expression can cause mitotic arrest. The Oncomine database is one of the largest oncogene chip databases in the world, and is an integrated data mining platform for cancer gene in...

journal_title：World journal of gastrointestinal oncology

authors： Liang WT,Liu XF,Huang HB,Gao ZM,Li K

更新日期：2020-10-15 00:00:00

abstract：:Laparoscopic and endoscopic cooperative surgery (LECS) is a surgical technique that combines laparoscopic partial gastrectomy and endoscopic submucosal dissection. LECS requires close collaboration between skilled laparoscopic surgeons and experienced endoscopists. For successful LECS, experience alone is not sufficie...

journal_title：World journal of gastrointestinal oncology

authors： Aisu Y,Yasukawa D,Kimura Y,Hori T

更新日期：2018-11-15 00:00:00

abstract：:Peritoneal carcinomatosis (PC) from gastric cancer has traditionally been considered a terminal progression of the disease and is associated with poor survival outcomes. Positive peritoneal cytology similarly worsens the survival of patients with gastric cancer and treatment options for these patients have been limite...

journal_title：World journal of gastrointestinal oncology

authors： Leiting JL,Grotz TE

更新日期：2018-10-15 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy has been applied worldwide to improve the survival of patients with gastric adenocarcinoma (GAC). The evaluation of histological regression in primary tumors is valuable for predicting prognosis. However, the prognostic effect of regression change in lymph nodes (LNs) remains unclear...

journal_title：World journal of gastrointestinal oncology

authors： Zhu YL,Sun YK,Xue XM,Yue JY,Yang L,Xue LY

更新日期：2019-01-15 00:00:00

abstract：AIM:To investigate p16 gene methylation and its expression in 30 patients with sporadic colorectal adenocarcinoma in a North Indian population. METHODS:Methylation specific polymerase chain reaction was used to detect p16 gene methylation and immunohistochemistry was used to study the p16 expression in 30 sporadic col...

journal_title：World journal of gastrointestinal oncology

authors： Malhotra P,Kochhar R,Vaiphei K,Wig JD,Mahmood S

更新日期：2010-07-15 00:00:00

abstract：:Progress in the molecular oncology of gastrointestinal carcinomas depends on high quality cancer tissues for research. Recent acceleration on new technological platforms as well as the "omics" revolution increases the demands on tissues and peripheral blood for research at the DNA, mRNA and protein levels. Tissue bank...

journal_title：World journal of gastrointestinal oncology

authors： Yu YY,Zhu ZG

更新日期：2010-01-15 00:00:00

abstract：:Cholangiocarcinoma (CCA) is a rare cancer arising from the biliary tree with a poor prognosis and limited therapeutic options. Recent large scale molecular characterisation studies have identified recurrent genetic alterations in CCA which may be amenable to therapeutic targeting. In this review we explore the genomic...

journal_title：World journal of gastrointestinal oncology

authors： Kayhanian H,Smyth EC,Braconi C

更新日期：2017-07-15 00:00:00

abstract：:Diarrhea is a common side effect of chemotherapy. Pseudomembranous colitis is a well known complication of antibiotic treatment that can also be observed, albeit rarely, with certain chemotherapeutic agents. We present four cases of severe colitis in patients undergoing treatment with taxane-based chemotherapy for pan...

journal_title：World journal of gastrointestinal oncology

authors： Carrion AF,Hosein PJ,Cooper EM,Lopes G,Pelaez L,Rocha-Lima CM

更新日期：2010-10-15 00:00:00

abstract：BACKGROUND:Long non-coding RNAs (lncRNAs) are a kind of single-stranded RNA of more than 200 nucleotides in length and have no protein-coding function. Amounting studies have indicated that lncRNAs could play a vital role in the initiation and development of cancers, including gastric cancer (GC). Considering the cruci...

journal_title：World journal of gastrointestinal oncology

authors： Komaç Ö,Bengi G,Sağol Ö,Akarsu M

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:Esophagectomy is a pivotal curative modality for localized esophageal or esophagogastric junction cancer (EC or EJC). Postoperative anastomotic leakage (AL) remains problematic. The use of fibrin sealant (FS) may improve the strength of esophageal anastomosis and reduce the incidence of AL. AIM:To assess th...

journal_title：World journal of gastrointestinal oncology

authors： Lin YB,Fu JH,Huang Y,Hu YH,Luo KJ,Wang KX,Bella AÉ,Situ DR,Chen JY,Lin T,D'Journo XB,Novoa NM,Brunelli A,Fernando HC,Cerfolio RJ,Ismail M,Yang H,AME Thoracic Surgery Collaborative Group.

更新日期：2020-06-15 00:00:00

abstract：:Gastric cancer is the third leading cause of cancer death worldwide. Even though during these last decades gastric cancer incidence decreased in Western countries, it remains endemic and with a high incidence in Eastern countries. The survival in advanced and metastatic stage of gastric cancer is still very poor. Rece...

journal_title：World journal of gastrointestinal oncology

authors： Satolli MA,Buffoni L,Spadi R,Roato I

更新日期：2015-11-15 00:00:00

abstract：:Standard pancreatic resections, such as pancreaticoduodenectomy, distal pancreatectomy, or total pancreatectomy, result in an important loss of normal pancreatic parenchyma and may cause impairment of exocrine and endocrine function. Whilst these procedures are mandatory for malignant tumors, they seem to be too exten...

journal_title：World journal of gastrointestinal oncology

authors： Sperti C,Beltrame V,Milanetto AC,Moro M,Pedrazzoli S

更新日期：2010-06-15 00:00:00