Do the benefits outweigh the side effects of colorectal cancer surveillance? A systematic review.

Abstract:

:Most patients treated with curative intent for colorectal cancer (CRC) are included in a follow-up program involving periodic evaluations. The survival benefits of a follow-up program are well delineated, and previous meta-analyses have suggested an overall survival improvement of 5%-10% by intensive follow-up. However, in a recent randomized trial, there was no survival benefit when a minimal vs an intensive follow-up program was compared. Less is known about the potential side effects of follow-up. Well-known side effects of preventive programs are those of somatic complications caused by testing, negative psychological consequences of follow-up itself, and the downstream impact of false positive or false negative tests. Accordingly, the potential survival benefits of CRC follow-up must be weighed against these potential negatives. The present review compares the benefits and side effects of CRC follow-up, and we propose future areas for research.

authors

Augestad KM,Rose J,Crawshaw B,Cooper G,Delaney C

doi

10.4251/wjgo.v6.i5.104

subject

Has Abstract

pub_date

2014-05-15 00:00:00

pages

104-11

issue

5

issn

1948-5204

journal_volume

6

pub_type

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