Current strategies for malignant pedunculated colorectal polyps.

abstract：:Surgery remains the only chance of cure for pancreatic cancer, but only 15%-25% of patients present with resectable disease at the time of primary diagnosis. Important goals in clinical research must therefore be to allow early detection with suitable diagnostic procedures, to further broaden operation techniques and ...

journal_title：World journal of gastrointestinal oncology

authors： Sinn M,Bahra M,Denecke T,Travis S,Pelzer U,Riess H

更新日期：2016-03-15 00:00:00

abstract：:Non-neoplastic tumor-like lesions in the pancreas are uncommon. Here, we present a case of multiple solid pancreatic hamartomas in a 78-year-old Japanese woman. Her computed tomography revealed a pancreatic mass, measuring 1.8 cm in maximum diameter. However, no symptoms were found. She was not an alcoholic and had no...

journal_title：World journal of gastrointestinal oncology

authors： Kawakami F,Shimizu M,Yamaguchi H,Hara S,Matsumoto I,Ku Y,Itoh T

更新日期：2012-09-15 00:00:00

abstract：:Progress in the molecular oncology of gastrointestinal carcinomas depends on high quality cancer tissues for research. Recent acceleration on new technological platforms as well as the "omics" revolution increases the demands on tissues and peripheral blood for research at the DNA, mRNA and protein levels. Tissue bank...

journal_title：World journal of gastrointestinal oncology

authors： Yu YY,Zhu ZG

更新日期：2010-01-15 00:00:00

abstract：:In an effort to minimize the limitations of laparoscopy, a robotic surgery system was introduced, but its role for gastric cancer is still unclear. The objective of this article is to assess the current status of robotic surgery for gastric cancer and to predict future prospects. Although the current study was limited...

journal_title：World journal of gastrointestinal oncology

authors： Baek SJ,Lee DW,Park SS,Kim SH

更新日期：2011-10-15 00:00:00

abstract：:Over the past ten years, sorafenib, a multikinase inhibitor, has been the standard of care for patients with unresectable hepatocellular carcinoma (HCC) and well-preserved liver function. Recently, lenvatinib, a different multikinase inhibitor, was shown to be non-inferior to sorafenib, in terms of survival, while all...

journal_title：World journal of gastrointestinal oncology

authors： Personeni N,Pressiani T,Bozzarelli S,Rimassa L

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Overexpression of SQSTM1 (sequestosome 1, P62) and nuclear factor-κB (NF-κB) plays an important role in the invasion and metastasis of a variety of malignant tumors. AIM:To explore the expression of P62 and NF-κB in pancreatic cancer and their relationship with clinicopathological features. METHODS:The exp...

journal_title：World journal of gastrointestinal oncology

authors： Zhang ZY,Guo S,Zhao R,Ji ZP,Zhuang ZN

更新日期：2020-07-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fifth leading cause of cancer mortality in the United States and the second leading cause of cancer mortality worldwide. Sorafenib is the only food and drug administration (FDA) approved as first line systemic treatment in HCC. Regorafenib and nivolumab are the only FDA approved s...

journal_title：World journal of gastrointestinal oncology

authors： Contratto M,Wu J

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:It has been recognized for a long time that gastric cancer behavior and outcomes might be different between patients living in Asian countries vs patients living in Western countries. It is not clear if these differences would persist between patients of Asian ancestry and patients of other racial subgroups ...

journal_title：World journal of gastrointestinal oncology

authors： Abdel-Rahman O

更新日期：2019-12-15 00:00:00

abstract：:Pancreaticobiliary maljunction (PBM) is a high risk factor for biliary tract cancer. In PBM, since the pancreatic duct and bile duct converge outside the duodenal wall beyond the influence of the sphincter of Oddi, pancreatic juice and bile are constantly mixed, producing a variety of harmful substances. Because of th...

journal_title：World journal of gastrointestinal oncology

authors： Tsuchida A,Itoi T

更新日期：2010-03-15 00:00:00

abstract：:Pancreatic surgery for malignancy is recognized as challenging for the surgeons and risky for the patients due to consistent perioperative morbidity and mortality. Furthermore, the oncological long-term results are largely disappointing, even for those patients who experience an uneventfully hospital stay. Nevertheles...

journal_title：World journal of gastrointestinal oncology

authors： Bencini L,Annecchiarico M,Farsi M,Bartolini I,Mirasolo V,Guerra F,Coratti A

更新日期：2015-12-15 00:00:00

abstract：AIM:To assess the practice of Egyptian physicians in screening patients for hepatocellular carcinoma (HCC). METHODS:The study included 154 physicians from all over Egypt caring for patients at risk for HCC. The study was based on a questionnaire with 20 items. Each questionnaire consisted of two parts: (1) personal in...

journal_title：World journal of gastrointestinal oncology

authors： Hassany SM,Moustafa EF,Taher ME,Abdeltwab AA,Blum HE

更新日期：2015-09-15 00:00:00

abstract：:Paraneoplastic leukemoid reaction is a rare syndrome defined by a leukocyte count exceeding 50 Giga/Liter (G/L), mostly described with progressive lung or renal carcinoma. We report a case of a 68-year-old man with recurrent pancreatic carcinoma presenting a leukemoid reaction with a white blood cell count of 63.87 G/...

journal_title：World journal of gastrointestinal oncology

authors： Dos Santos M,Bouhier K,Dao MT

更新日期：2015-10-15 00:00:00

abstract：:While the incidence and mortality of gastric cancer (GC) have declined due to public health programs, it remains the third deadliest cancer worldwide. For patients with early disease, innovative endoscopic and complex surgical techniques have improved survival. However, for patients with advanced disease, there are li...

journal_title：World journal of gastrointestinal oncology

authors： Lin M,Gao M,Cavnar MJ,Kim J

更新日期：2019-07-15 00:00:00

abstract：AIM:To identify genetic polymorphisms in the promoter region of the human base excision repair gene NEIL1 in gastric cancer patients. METHODS:The NEIL1 promoter region in DNA from 80 Japanese patients with gastric cancer was searched for genetic polymorphisms by polymerase chain reaction-single-strand conformation pol...

journal_title：World journal of gastrointestinal oncology

authors： Goto M,Shinmura K,Tao H,Tsugane S,Sugimura H

更新日期：2010-02-15 00:00:00

abstract：BACKGROUND:Bile duct cancer constitutes gallbladder cancer (GBC), intrahepatic cholangiocarcinoma (ICA), and extrahepatic cholangiocarcinoma (ECA). These three entities show morphological and immunohistochemical resemblance so that it is difficult to differentiate between primary ICA and liver metastasis of GBC, which ...

journal_title：World journal of gastrointestinal oncology

authors： Inagaki C,Maeda D,Kimura A,Otsuru T,Iwagami Y,Nishida N,Sakai D,Shitotsuki R,Yachida S,Doki Y,Satoh T

更新日期：2019-09-15 00:00:00

abstract：:Pneumo-computed tomography (PnCT) is a technique primarily developed and used to study stenotic lesions of the esophagus, gastroesophageal junction and stomach for pre-surgical planning. It helps to define both upper and lower borders of neoplasms located in the aforementioned areas. It achieves maximum lumen distensi...

journal_title：World journal of gastrointestinal oncology

authors： Ulla M,Gentile E,Yeyati EL,Diez ML,Cavadas D,Garcia-Monaco RD,Ros PR

更新日期：2013-12-15 00:00:00

abstract：BACKGROUND:Reports in the field of robotic surgery for rectal cancer are increasing year by year. However, most of these studies enroll patients at a relatively early stage and have small sample sizes. In fact, studies only on patients with locally advanced rectal cancer (LARC) and with relatively large sample sizes ar...

journal_title：World journal of gastrointestinal oncology

authors： Ye SP,Zhu WQ,Liu DN,Lei X,Jiang QG,Hu HM,Tang B,He PH,Gao GM,Tang HC,Shi J,Li TY

更新日期：2020-04-15 00:00:00

abstract：:Laparoscopic and endoscopic cooperative surgery (LECS) is a surgical technique that combines laparoscopic partial gastrectomy and endoscopic submucosal dissection. LECS requires close collaboration between skilled laparoscopic surgeons and experienced endoscopists. For successful LECS, experience alone is not sufficie...

journal_title：World journal of gastrointestinal oncology

authors： Aisu Y,Yasukawa D,Kimura Y,Hori T

更新日期：2018-11-15 00:00:00

abstract：:Gastric cancer is the third leading cause of cancer death worldwide. Even though during these last decades gastric cancer incidence decreased in Western countries, it remains endemic and with a high incidence in Eastern countries. The survival in advanced and metastatic stage of gastric cancer is still very poor. Rece...

journal_title：World journal of gastrointestinal oncology

authors： Satolli MA,Buffoni L,Spadi R,Roato I

更新日期：2015-11-15 00:00:00

abstract：:Gastrointestinal neuroendocrine tumors are rare slow-growing tumors with distinct histological, biological, and clinical characteristics that have increased in incidence and prevalence within the last few decades. They contain chromogranin A, synaptophysin and neuron-specific enolase which are necessary for making a d...

journal_title：World journal of gastrointestinal oncology

authors： Ahmed M

更新日期：2020-08-15 00:00:00

abstract：BACKGROUND:Brain metastasis (BM) from colorectal cancer (CRC) is rarely encountered clinically, and its prognosis has not been fully evaluated. AIM:To construct a scoring system and accurately predict the survival of patients with synchronous BM at diagnosis of CRC. METHODS:A retrospective study of 371 patients with ...

journal_title：World journal of gastrointestinal oncology

authors： Quan JC,Guan X,Ma CX,Liu Z,Yang M,Zhao ZX,Sun P,Zhuang M,Wang S,Jiang Z,Wang XS

更新日期：2020-02-15 00:00:00

abstract：:5-flurouracil (5-FU)-based chemotherapy is the main pharmacological therapy for advanced colorectal cancer (CRC). Despite significant progress in the treatment of CRC during the last decades, 5-FU drug resistance remains the most important cause of failure in CRC therapy. Resistance to 5-FU is a complex and multistep ...

journal_title：World journal of gastrointestinal oncology

authors： Sabeti Aghabozorgi A,Moradi Sarabi M,Jafarzadeh-Esfehani R,Koochakkhani S,Hassanzadeh M,Kavousipour S,Eftekhar E

更新日期：2020-09-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the second leading cause of cancer mortality worldwide. The cornerstone to improving the prognosis of HCC patients has been the control of loco-regional disease progression and the lesser toxicities of local treatment. Although radiotherapy has not...

journal_title：World journal of gastrointestinal oncology

authors： Hsu CY,Wang CW,Cheng AL,Kuo SH

更新日期：2019-08-15 00:00:00

abstract：:Deficiencies in DNA repair due to inherited germ-line mutations in DNA repair genes cause increased risk of gastrointestinal (GI) cancer. In sporadic GI cancers, mutations in DNA repair genes are relatively rare. However, epigenetic alterations that reduce expression of DNA repair genes are frequent in sporadic GI can...

journal_title：World journal of gastrointestinal oncology

authors： Bernstein C,Bernstein H

更新日期：2015-05-15 00:00:00

abstract：AIM:To study tumor response, and tolerability of arterially directed embolic therapy (ADET) with polyethylene glycol embolics loaded with irinotecan for the treatment of colorectal cancer liver metastases (CRC-LM). Secondary objectives were to monitor quality of life, time to progression and survival of patients. METH...

journal_title：World journal of gastrointestinal oncology

authors： Fiorentini G,Carandina R,Sarti D,Nardella M,Zoras O,Guadagni S,Inchingolo R,Nestola M,Felicioli A,Barnes Navarro D,Munoz Gomez F,Aliberti C

更新日期：2017-09-15 00:00:00

abstract：:Standard pancreatic resections, such as pancreaticoduodenectomy, distal pancreatectomy, or total pancreatectomy, result in an important loss of normal pancreatic parenchyma and may cause impairment of exocrine and endocrine function. Whilst these procedures are mandatory for malignant tumors, they seem to be too exten...

journal_title：World journal of gastrointestinal oncology

authors： Sperti C,Beltrame V,Milanetto AC,Moro M,Pedrazzoli S

更新日期：2010-06-15 00:00:00

abstract：:Digestive endoscopy is currently the main diagnostic procedure for investigation of the digestive tract when a digestive disease is suspected. The use of computers and electronic medical records for the management of endoscopic data are an important key to improving endoscopy unit efficiency and productivity. This tec...

journal_title：World journal of gastrointestinal oncology

authors： Maserat E,Safdari R,Maserat E,Zali MR

更新日期：2012-04-15 00:00:00

abstract：:Because of the aging of the population, prevalence of medical checkups, and advances in imaging studies, the number of pancreatic cystic lesions detected has increased. Once these lesions are detected, neoplastic cysts should be differentiated from non-neoplastic cysts. Furthermore, because of the malignant potential ...

journal_title：World journal of gastrointestinal oncology

authors： Kawaguchi Y,Mine T

更新日期：2016-02-15 00:00:00

abstract：:Cancer research over the past decades has focused on neoplastic cells, or a fraction of them, i.e. tumor stem cells, as the ultimate causes of tumorigenesis. However, during recent years, scientists have come to realize that tumorigenesis is not a solo act of neoplastic cells, but rather a cooperative process in which...

journal_title：World journal of gastrointestinal oncology

authors： Zhu J,Ding J,Ding F

更新日期：2010-05-15 00:00:00

abstract：BACKGROUND:Regorafenib is an oral small-molecule multikinase inhibitor approved in third or later line of treatment for patients with metastatic colorectal cancer (mCRC). Regorafenib has shown significant benefits in overall survival and progression free survival in two phase III trials compared to placebo in patients ...

journal_title：World journal of gastrointestinal oncology

authors： Ricci V,Granetto C,Falletta A,Paccagnella M,Abbona A,Fea E,Fabozzi T,Lo Nigro C,Merlano MC

更新日期：2020-03-15 00:00:00