Paraneoplastic leukemoid reaction in pancreatic cancer: A case report.

abstract：:Adenocarcinoma of small intestines (SBA) is a relatively rare malignancy with poor outcomes due to delayed diagnosis. Fifty percent of patients have metastases on presentation and therefore early detection and treatment offers the best long term outcomes. Certain genetic polyposis syndromes and familial diseases are a...

journal_title：World journal of gastrointestinal oncology

authors： Shenoy S

更新日期：2016-06-15 00:00:00

abstract：:Deficiencies in DNA repair due to inherited germ-line mutations in DNA repair genes cause increased risk of gastrointestinal (GI) cancer. In sporadic GI cancers, mutations in DNA repair genes are relatively rare. However, epigenetic alterations that reduce expression of DNA repair genes are frequent in sporadic GI can...

journal_title：World journal of gastrointestinal oncology

authors： Bernstein C,Bernstein H

更新日期：2015-05-15 00:00:00

abstract：:Peritoneal carcinomatosis (PC) from gastric cancer has traditionally been considered a terminal progression of the disease and is associated with poor survival outcomes. Positive peritoneal cytology similarly worsens the survival of patients with gastric cancer and treatment options for these patients have been limite...

journal_title：World journal of gastrointestinal oncology

authors： Leiting JL,Grotz TE

更新日期：2018-10-15 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy has been applied worldwide to improve the survival of patients with gastric adenocarcinoma (GAC). The evaluation of histological regression in primary tumors is valuable for predicting prognosis. However, the prognostic effect of regression change in lymph nodes (LNs) remains unclear...

journal_title：World journal of gastrointestinal oncology

authors： Zhu YL,Sun YK,Xue XM,Yue JY,Yang L,Xue LY

更新日期：2019-01-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a highly malignant tumor and extrahepatic metastasis is not rare. The most common organ of HCC metastasis is lung, followed by bone and adrenal gland. To the best of our knowledge, isolated pancreatic metastasis of HCC that developed after curative resection has not been described pre...

journal_title：World journal of gastrointestinal oncology

authors： Woo SM,Park JW,Han SS,Choi JI,Lee WJ,Park SJ,Hong EK,Kim CM

更新日期：2010-04-15 00:00:00

abstract：:5-flurouracil (5-FU)-based chemotherapy is the main pharmacological therapy for advanced colorectal cancer (CRC). Despite significant progress in the treatment of CRC during the last decades, 5-FU drug resistance remains the most important cause of failure in CRC therapy. Resistance to 5-FU is a complex and multistep ...

journal_title：World journal of gastrointestinal oncology

authors： Sabeti Aghabozorgi A,Moradi Sarabi M,Jafarzadeh-Esfehani R,Koochakkhani S,Hassanzadeh M,Kavousipour S,Eftekhar E

更新日期：2020-09-15 00:00:00

abstract：:Digestive endoscopy is currently the main diagnostic procedure for investigation of the digestive tract when a digestive disease is suspected. The use of computers and electronic medical records for the management of endoscopic data are an important key to improving endoscopy unit efficiency and productivity. This tec...

journal_title：World journal of gastrointestinal oncology

authors： Maserat E,Safdari R,Maserat E,Zali MR

更新日期：2012-04-15 00:00:00

abstract：:Intussusception is a rare condition in the adult population. However, in contrast to its presentation in children, an identifiable etiology is found in the majority of cases. Clinical manifestations of adult intussusception are non-specific and patients may present with acute, intermittent or chronic symptoms, predomi...

journal_title：World journal of gastrointestinal oncology

authors： Nuño-Guzmán CM,Arróniz-Jáuregui J,Espejo I,Solís-Ugalde J,Gómez-Ontiveros JI,Vargas-Gerónimo A,Valle-González J

更新日期：2011-06-15 00:00:00

abstract：:A field defect is a field of pre-malignant tissue in which a new cancer is likely to arise. Field defects often appear to be histologically normal under the microscope. Recent research indicates that cells within a field defect characteristically have an increased frequency of epigenetic alterations and these may be f...

journal_title：World journal of gastrointestinal oncology

authors： Bernstein C,Nfonsam V,Prasad AR,Bernstein H

更新日期：2013-03-15 00:00:00

abstract：:Standard pancreatic resections, such as pancreaticoduodenectomy, distal pancreatectomy, or total pancreatectomy, result in an important loss of normal pancreatic parenchyma and may cause impairment of exocrine and endocrine function. Whilst these procedures are mandatory for malignant tumors, they seem to be too exten...

journal_title：World journal of gastrointestinal oncology

authors： Sperti C,Beltrame V,Milanetto AC,Moro M,Pedrazzoli S

更新日期：2010-06-15 00:00:00

abstract：BACKGROUND:Long non-coding RNAs (lncRNAs) are a kind of single-stranded RNA of more than 200 nucleotides in length and have no protein-coding function. Amounting studies have indicated that lncRNAs could play a vital role in the initiation and development of cancers, including gastric cancer (GC). Considering the cruci...

journal_title：World journal of gastrointestinal oncology

authors： Komaç Ö,Bengi G,Sağol Ö,Akarsu M

更新日期：2019-02-15 00:00:00

abstract：:Pancreatic adenocarcinoma is the fourth cause of cancer-related death in the United States. Surgery is the only potentially curative treatment, but most patients present at diagnosis with unresectable or metastatic disease. Moreover, even with an R0 resection, the majority of patients will die of disease recurrence. M...

journal_title：World journal of gastrointestinal oncology

authors： Sperti C,Moletta L,Merigliano S

更新日期：2015-12-15 00:00:00

abstract：AIM:To investigate p16 gene methylation and its expression in 30 patients with sporadic colorectal adenocarcinoma in a North Indian population. METHODS:Methylation specific polymerase chain reaction was used to detect p16 gene methylation and immunohistochemistry was used to study the p16 expression in 30 sporadic col...

journal_title：World journal of gastrointestinal oncology

authors： Malhotra P,Kochhar R,Vaiphei K,Wig JD,Mahmood S

更新日期：2010-07-15 00:00:00

abstract：BACKGROUND:Radical D2 lymphadenectomy for advanced gastric cancer as a standard procedure has gained global consensus. Mounting studies have shown that the number of lymph nodes dissection directly affects the prognosis and recurrence of gastric cancer. Our previous study showed that there was no obvious lymph node aro...

journal_title：World journal of gastrointestinal oncology

authors： Mu GC,Huang Y,Liu ZM,Chen ZB,Wu XH,Qin XG,Zeng YJ

更新日期：2019-06-15 00:00:00

abstract：:Pancreatic surgery for malignancy is recognized as challenging for the surgeons and risky for the patients due to consistent perioperative morbidity and mortality. Furthermore, the oncological long-term results are largely disappointing, even for those patients who experience an uneventfully hospital stay. Nevertheles...

journal_title：World journal of gastrointestinal oncology

authors： Bencini L,Annecchiarico M,Farsi M,Bartolini I,Mirasolo V,Guerra F,Coratti A

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Epstein-Barr virus (EBV)-associated carcinoma is a gastric cancer subtype with a morphology characterized by gastric carcinoma with lymphoid stroma (GCLS). Clinicopathological studies have indicated a better prognosis for GCLS than for common gastric carcinomas. Some previous cases of early gastric cancer as...

journal_title：World journal of gastrointestinal oncology

authors： Kobayashi Y,Kunogi T,Tanabe H,Murakami Y,Iwama T,Sasaki T,Takahashi K,Ando K,Nomura Y,Ueno N,Kashima S,Moriichi K,Takei H,Fujiya M,Okumura T

更新日期：2019-10-15 00:00:00

abstract：:While the incidence and mortality of gastric cancer (GC) have declined due to public health programs, it remains the third deadliest cancer worldwide. For patients with early disease, innovative endoscopic and complex surgical techniques have improved survival. However, for patients with advanced disease, there are li...

journal_title：World journal of gastrointestinal oncology

authors： Lin M,Gao M,Cavnar MJ,Kim J

更新日期：2019-07-15 00:00:00

abstract：:It is well established that colorectal cancer develops from a series of precursor epithelial polyps, including tubular adenomas, villous/tubulovillous adenomas (VA/TVA), sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA). Of these, TSAs are least common and account for only 5% of all serrated poly...

journal_title：World journal of gastrointestinal oncology

authors： Kalimuthu SN,Chelliah A,Chetty R

更新日期：2016-12-15 00:00:00

abstract：:Most patients treated with curative intent for colorectal cancer (CRC) are included in a follow-up program involving periodic evaluations. The survival benefits of a follow-up program are well delineated, and previous meta-analyses have suggested an overall survival improvement of 5%-10% by intensive follow-up. Howeve...

journal_title：World journal of gastrointestinal oncology

authors： Augestad KM,Rose J,Crawshaw B,Cooper G,Delaney C

更新日期：2014-05-15 00:00:00

abstract：:Low rectal cancer is traditionally treated by abdominoperineal resection. In recent years, several new techniques for the treatment of very low rectal cancer patients aiming to preserve the gastrointestinal continuity and to improve both the oncological as well as the functional outcomes, have been emerged. Literature...

journal_title：World journal of gastrointestinal oncology

authors： Dimitriou N,Michail O,Moris D,Griniatsos J

更新日期：2015-07-15 00:00:00

abstract：BACKGROUND:Regorafenib is an oral small-molecule multikinase inhibitor approved in third or later line of treatment for patients with metastatic colorectal cancer (mCRC). Regorafenib has shown significant benefits in overall survival and progression free survival in two phase III trials compared to placebo in patients ...

journal_title：World journal of gastrointestinal oncology

authors： Ricci V,Granetto C,Falletta A,Paccagnella M,Abbona A,Fea E,Fabozzi T,Lo Nigro C,Merlano MC

更新日期：2020-03-15 00:00:00

abstract：:Pancreaticobiliary maljunction (PBM) is a high risk factor for biliary tract cancer. In PBM, since the pancreatic duct and bile duct converge outside the duodenal wall beyond the influence of the sphincter of Oddi, pancreatic juice and bile are constantly mixed, producing a variety of harmful substances. Because of th...

journal_title：World journal of gastrointestinal oncology

authors： Tsuchida A,Itoi T

更新日期：2010-03-15 00:00:00

abstract：:A 40-year-old male, diagnosed with mild Crohn's disease (CD) 11 years ago but with no prior abdominal surgeries, was diagnosed with a small bowel stricture, due to ongoing abdominal pain and intolerance of enteral diet, and referred for surgical treatment. Exploratory laparoscopy revealed a white solid mass causing a ...

journal_title：World journal of gastrointestinal oncology

authors： Drukker L,Edden Y,Reissman P

更新日期：2012-07-15 00:00:00

abstract：BACKGROUND:Recent studies have proved the important role of many oncogenic long non-coding RNAs (lncRNAs) in the progression of pancreatic cancer, but little is known about the mechanisms of tumor suppression in pancreatic cancer. AIM:To evaluate the function of tumor suppressor lncRNA C9orf139 in pancreatic cancer pr...

journal_title：World journal of gastrointestinal oncology

authors： Ge JN,Yan D,Ge CL,Wei MJ

更新日期：2020-11-15 00:00:00

abstract：BACKGROUND:Kinesin super family 23 (KIF23) is a member of the KIF family, and it plays an important role in mitosis and cytokinesis. Loss of expression can cause mitotic arrest. The Oncomine database is one of the largest oncogene chip databases in the world, and is an integrated data mining platform for cancer gene in...

journal_title：World journal of gastrointestinal oncology

authors： Liang WT,Liu XF,Huang HB,Gao ZM,Li K

更新日期：2020-10-15 00:00:00

abstract：AIM:To examine survival outcomes of perihilar cholangiocarcinoma (PCCA) resection including mortality, morbidity and prognostic factors. METHODS:Multivariate analyses were carried out based on the survival data of all patients with histologically confirmed PCCA who underwent curative resection at Srinagarind Hospital ...

journal_title：World journal of gastrointestinal oncology

authors： Titapun A,Pugkhem A,Luvira V,Srisuk T,Somintara O,Saeseow OT,Sripanuskul A,Nimboriboonporn A,Thinkhamrop B,Khuntikeo N

更新日期：2015-12-15 00:00:00

abstract：:Because of the aging of the population, prevalence of medical checkups, and advances in imaging studies, the number of pancreatic cystic lesions detected has increased. Once these lesions are detected, neoplastic cysts should be differentiated from non-neoplastic cysts. Furthermore, because of the malignant potential ...

journal_title：World journal of gastrointestinal oncology

authors： Kawaguchi Y,Mine T

更新日期：2016-02-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fifth leading cause of cancer mortality in the United States and the second leading cause of cancer mortality worldwide. Sorafenib is the only food and drug administration (FDA) approved as first line systemic treatment in HCC. Regorafenib and nivolumab are the only FDA approved s...

journal_title：World journal of gastrointestinal oncology

authors： Contratto M,Wu J

更新日期：2018-05-15 00:00:00

abstract：:Casein kinase I is a group of ubiquitous Serine/Threonine kinases that have been implicated in both normal cellular functions and several pathological conditions including Alzheimer's disease and cancer. Recent findings in colon and pancreatic cancer have brought tremendous attention to these molecules as potential th...

journal_title：World journal of gastrointestinal oncology

authors： Modak C,Chai J

更新日期：2009-10-15 00:00:00

abstract：:Cancer research over the past decades has focused on neoplastic cells, or a fraction of them, i.e. tumor stem cells, as the ultimate causes of tumorigenesis. However, during recent years, scientists have come to realize that tumorigenesis is not a solo act of neoplastic cells, but rather a cooperative process in which...

journal_title：World journal of gastrointestinal oncology

authors： Zhu J,Ding J,Ding F

更新日期：2010-05-15 00:00:00