Carcinogenesis and chemoprevention of biliary tract cancer in pancreaticobiliary maljunction.

abstract：BACKGROUND:Reports in the field of robotic surgery for rectal cancer are increasing year by year. However, most of these studies enroll patients at a relatively early stage and have small sample sizes. In fact, studies only on patients with locally advanced rectal cancer (LARC) and with relatively large sample sizes ar...

journal_title：World journal of gastrointestinal oncology

authors： Ye SP,Zhu WQ,Liu DN,Lei X,Jiang QG,Hu HM,Tang B,He PH,Gao GM,Tang HC,Shi J,Li TY

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Long non-coding RNAs (lncRNAs) are a kind of single-stranded RNA of more than 200 nucleotides in length and have no protein-coding function. Amounting studies have indicated that lncRNAs could play a vital role in the initiation and development of cancers, including gastric cancer (GC). Considering the cruci...

journal_title：World journal of gastrointestinal oncology

authors： Komaç Ö,Bengi G,Sağol Ö,Akarsu M

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:Radical D2 lymphadenectomy for advanced gastric cancer as a standard procedure has gained global consensus. Mounting studies have shown that the number of lymph nodes dissection directly affects the prognosis and recurrence of gastric cancer. Our previous study showed that there was no obvious lymph node aro...

journal_title：World journal of gastrointestinal oncology

authors： Mu GC,Huang Y,Liu ZM,Chen ZB,Wu XH,Qin XG,Zeng YJ

更新日期：2019-06-15 00:00:00

abstract：:Over the past ten years, sorafenib, a multikinase inhibitor, has been the standard of care for patients with unresectable hepatocellular carcinoma (HCC) and well-preserved liver function. Recently, lenvatinib, a different multikinase inhibitor, was shown to be non-inferior to sorafenib, in terms of survival, while all...

journal_title：World journal of gastrointestinal oncology

authors： Personeni N,Pressiani T,Bozzarelli S,Rimassa L

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Epstein-Barr virus (EBV)-associated carcinoma is a gastric cancer subtype with a morphology characterized by gastric carcinoma with lymphoid stroma (GCLS). Clinicopathological studies have indicated a better prognosis for GCLS than for common gastric carcinomas. Some previous cases of early gastric cancer as...

journal_title：World journal of gastrointestinal oncology

authors： Kobayashi Y,Kunogi T,Tanabe H,Murakami Y,Iwama T,Sasaki T,Takahashi K,Ando K,Nomura Y,Ueno N,Kashima S,Moriichi K,Takei H,Fujiya M,Okumura T

更新日期：2019-10-15 00:00:00

abstract：:Colorectal carcinogenesis (CRC) imposes a major health burden in developing countries. It is the third major cause of cancer deaths. Despite several treatment strategies, novel drugs are warranted to reduce the severity of this disease. Adenomatous polyps in the colon are the major culprits in CRC and found in 45% of ...

journal_title：World journal of gastrointestinal oncology

authors： Pandurangan AK,Divya T,Kumar K,Dineshbabu V,Velavan B,Sudhandiran G

更新日期：2018-09-15 00:00:00

abstract：BACKGROUND:Overexpression of SQSTM1 (sequestosome 1, P62) and nuclear factor-κB (NF-κB) plays an important role in the invasion and metastasis of a variety of malignant tumors. AIM:To explore the expression of P62 and NF-κB in pancreatic cancer and their relationship with clinicopathological features. METHODS:The exp...

journal_title：World journal of gastrointestinal oncology

authors： Zhang ZY,Guo S,Zhao R,Ji ZP,Zhuang ZN

更新日期：2020-07-15 00:00:00

abstract：:A field defect is a field of pre-malignant tissue in which a new cancer is likely to arise. Field defects often appear to be histologically normal under the microscope. Recent research indicates that cells within a field defect characteristically have an increased frequency of epigenetic alterations and these may be f...

journal_title：World journal of gastrointestinal oncology

authors： Bernstein C,Nfonsam V,Prasad AR,Bernstein H

更新日期：2013-03-15 00:00:00

abstract：:Pancreatic cancer, with a 5% 5-year survival rate, is the fourth leading cause of cancer death in Western countries. Unfortunately, only 20% of all patients benefit from surgical treatment. The need to prolong survival has prompted pathologists to develop improved protocols to evaluate pancreatic specimens and their s...

journal_title：World journal of gastrointestinal oncology

authors： Gómez-Mateo Mdel C,Sabater-Ortí L,Ferrández-Izquierdo A

更新日期：2014-09-15 00:00:00

abstract：:Low rectal cancer is traditionally treated by abdominoperineal resection. In recent years, several new techniques for the treatment of very low rectal cancer patients aiming to preserve the gastrointestinal continuity and to improve both the oncological as well as the functional outcomes, have been emerged. Literature...

journal_title：World journal of gastrointestinal oncology

authors： Dimitriou N,Michail O,Moris D,Griniatsos J

更新日期：2015-07-15 00:00:00

abstract：BACKGROUND:Toll-like receptors (TLRs) are the first line of host defense, and are involved in Helicobacter pylori (H. pylori) recognition and activation of both inflammatory and carcinogenic processes. The presence of single nucleotide polymorphisms (SNPs) in genes that activate the immune response may modulate the ris...

journal_title：World journal of gastrointestinal oncology

authors： Susi MD,Lourenço Caroline M,Rasmussen LT,Payão SLM,Rossi AFT,Silva AE,de Oliveira-Cucolo JG

更新日期：2019-11-15 00:00:00

abstract：:In an effort to minimize the limitations of laparoscopy, a robotic surgery system was introduced, but its role for gastric cancer is still unclear. The objective of this article is to assess the current status of robotic surgery for gastric cancer and to predict future prospects. Although the current study was limited...

journal_title：World journal of gastrointestinal oncology

authors： Baek SJ,Lee DW,Park SS,Kim SH

更新日期：2011-10-15 00:00:00

abstract：:Colorectal cancer is the second leading cause of death from cancer among adults. The disease begins as a benign adenomatous polyp, which develops into an advanced adenoma with high-grade dysplasia and then progresses to an invasive cancer. Appropriate apoptotic signaling is fundamentally important to preserve a health...

journal_title：World journal of gastrointestinal oncology

authors： Abraha AM,Ketema EB

更新日期：2016-08-15 00:00:00

abstract：:It is well established that colorectal cancer develops from a series of precursor epithelial polyps, including tubular adenomas, villous/tubulovillous adenomas (VA/TVA), sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA). Of these, TSAs are least common and account for only 5% of all serrated poly...

journal_title：World journal of gastrointestinal oncology

authors： Kalimuthu SN,Chelliah A,Chetty R

更新日期：2016-12-15 00:00:00

abstract：:5-flurouracil (5-FU)-based chemotherapy is the main pharmacological therapy for advanced colorectal cancer (CRC). Despite significant progress in the treatment of CRC during the last decades, 5-FU drug resistance remains the most important cause of failure in CRC therapy. Resistance to 5-FU is a complex and multistep ...

journal_title：World journal of gastrointestinal oncology

authors： Sabeti Aghabozorgi A,Moradi Sarabi M,Jafarzadeh-Esfehani R,Koochakkhani S,Hassanzadeh M,Kavousipour S,Eftekhar E

更新日期：2020-09-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fifth leading cause of cancer mortality in the United States and the second leading cause of cancer mortality worldwide. Sorafenib is the only food and drug administration (FDA) approved as first line systemic treatment in HCC. Regorafenib and nivolumab are the only FDA approved s...

journal_title：World journal of gastrointestinal oncology

authors： Contratto M,Wu J

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:Due to the special clinical features and biologic characteristics of adolescent and young adult (AYA) cancers, AYA cancers are different from cancers in children and elderly individuals. However, there are few reports on AYA hepatocellular carcinoma (HCC). AIM:To investigate the overall survival (OS) of AYA...

journal_title：World journal of gastrointestinal oncology

authors： Ren J,Tong YM,Cui RX,Wang Z,Li QL,Liu W,Qu K,Zhang JY,Liu C,Wan Y

更新日期：2020-12-15 00:00:00

abstract：:Gastric metastases from lung adenocarcinoma are rare. Because gastric metastasis grossly resembles advanced gastric cancer, it is difficult to diagnose gastric metastasis especially when the histology of the primary lung cancer is adenocarcinoma. We describe a case of gastric metastasis from primary lung adenocarcinom...

journal_title：World journal of gastrointestinal oncology

authors： Kim MJ,Hong JH,Park ES,Byun JH

更新日期：2015-03-15 00:00:00

abstract：:Digestive endoscopy is currently the main diagnostic procedure for investigation of the digestive tract when a digestive disease is suspected. The use of computers and electronic medical records for the management of endoscopic data are an important key to improving endoscopy unit efficiency and productivity. This tec...

journal_title：World journal of gastrointestinal oncology

authors： Maserat E,Safdari R,Maserat E,Zali MR

更新日期：2012-04-15 00:00:00

abstract：:Surgery remains the only chance of cure for pancreatic cancer, but only 15%-25% of patients present with resectable disease at the time of primary diagnosis. Important goals in clinical research must therefore be to allow early detection with suitable diagnostic procedures, to further broaden operation techniques and ...

journal_title：World journal of gastrointestinal oncology

authors： Sinn M,Bahra M,Denecke T,Travis S,Pelzer U,Riess H

更新日期：2016-03-15 00:00:00

abstract：:Gastrointestinal (GI) cancer has a high tumor incidence and mortality rate worldwide. Despite significant improvements in radiotherapy, chemotherapy, and targeted therapy for GI cancer over the last decade, GI cancer is characterized by high recurrence rates and a dismal prognosis. There is an urgent need for new diag...

journal_title：World journal of gastrointestinal oncology

authors： Matsuoka T,Yashiro M

更新日期：2020-01-15 00:00:00

abstract：AIM:To examine survival outcomes of perihilar cholangiocarcinoma (PCCA) resection including mortality, morbidity and prognostic factors. METHODS:Multivariate analyses were carried out based on the survival data of all patients with histologically confirmed PCCA who underwent curative resection at Srinagarind Hospital ...

journal_title：World journal of gastrointestinal oncology

authors： Titapun A,Pugkhem A,Luvira V,Srisuk T,Somintara O,Saeseow OT,Sripanuskul A,Nimboriboonporn A,Thinkhamrop B,Khuntikeo N

更新日期：2015-12-15 00:00:00

abstract：:Solid pseudopapillary neoplasm (SPN), also known as Gruber-Frantz tumor, is a rare form of neoplasm that almost exclusively occurs in the pancreas and in young females. While the potential of malignancy is low for SPN, these tumors can mimic other diseases and require a meticulous investigation and a standard treatmen...

journal_title：World journal of gastrointestinal oncology

authors： Wu H,Huang YF,Liu XH,Xu MH

更新日期：2017-12-15 00:00:00

abstract：:Cholangiocarcinoma (CCA) is a rare cancer arising from the biliary tree with a poor prognosis and limited therapeutic options. Recent large scale molecular characterisation studies have identified recurrent genetic alterations in CCA which may be amenable to therapeutic targeting. In this review we explore the genomic...

journal_title：World journal of gastrointestinal oncology

authors： Kayhanian H,Smyth EC,Braconi C

更新日期：2017-07-15 00:00:00

abstract：:Over the past couple of decades considerable progress has been made in the management of metastatic colorectal cancers (mCRC) leading to a significant improvement in five-year survival. Although part of this success has been rightly attributed to aggressive surgical management and advances in other adjunct treatments,...

journal_title：World journal of gastrointestinal oncology

authors： Pai SG,Fuloria J

更新日期：2016-01-15 00:00:00

abstract：AIM:To correct the misclassification in registered gastric cancer incidence across Iranian provinces in cancer registry data. METHODS:Gastric cancer data is extracted from Iranian annual of national cancer registration report 2008. A Bayesian method with beta prior is implemented to estimate the rate of misclassificat...

journal_title：World journal of gastrointestinal oncology

authors： Hajizadeh N,Pourhoseingholi MA,Baghestani AR,Abadi A,Zali MR

更新日期：2017-02-15 00:00:00

abstract：:Most patients treated with curative intent for colorectal cancer (CRC) are included in a follow-up program involving periodic evaluations. The survival benefits of a follow-up program are well delineated, and previous meta-analyses have suggested an overall survival improvement of 5%-10% by intensive follow-up. Howeve...

journal_title：World journal of gastrointestinal oncology

authors： Augestad KM,Rose J,Crawshaw B,Cooper G,Delaney C

更新日期：2014-05-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a highly malignant tumor and extrahepatic metastasis is not rare. The most common organ of HCC metastasis is lung, followed by bone and adrenal gland. To the best of our knowledge, isolated pancreatic metastasis of HCC that developed after curative resection has not been described pre...

journal_title：World journal of gastrointestinal oncology

authors： Woo SM,Park JW,Han SS,Choi JI,Lee WJ,Park SJ,Hong EK,Kim CM

更新日期：2010-04-15 00:00:00

abstract：BACKGROUND:Breast metastases from colorectal cancer (CRC) are very uncommon. There is no unanimous consensus regarding the best treatment for this rare condition, and management is, especially in elderly patients, limited to diagnosis and palliative care. Capecitabine, an oral fluoropyrimidine derivative, might be help...

journal_title：World journal of gastrointestinal oncology

authors： Taccogna S,Gozzi E,Rossi L,Caruso D,Conte D,Trenta P,Leoni V,Tomao S,Raimondi L,Angelini F

更新日期：2020-09-15 00:00:00

abstract：:Biliary tract carcinomas are relatively rare, representing less than 1% of cancers. However, their incidence has increased in Japan and in industrialized countries like the USA. Biliary tract tumors have a poor prognosis and a high mortality rate because they are usually detected late in the course of the disease; the...

journal_title：World journal of gastrointestinal oncology

authors： Malaguarnera G,Giordano M,Paladina I,Rando A,Uccello M,Basile F,Biondi A,Carnazzo S,Alessandria I,Mazzarino C

更新日期：2011-04-15 00:00:00