Apoptotic pathways as a therapeutic target for colorectal cancer treatment.

abstract：:Hepatocellular carcinoma (HCC) is a highly malignant tumor and extrahepatic metastasis is not rare. The most common organ of HCC metastasis is lung, followed by bone and adrenal gland. To the best of our knowledge, isolated pancreatic metastasis of HCC that developed after curative resection has not been described pre...

journal_title：World journal of gastrointestinal oncology

authors： Woo SM,Park JW,Han SS,Choi JI,Lee WJ,Park SJ,Hong EK,Kim CM

更新日期：2010-04-15 00:00:00

abstract：:Cancer research over the past decades has focused on neoplastic cells, or a fraction of them, i.e. tumor stem cells, as the ultimate causes of tumorigenesis. However, during recent years, scientists have come to realize that tumorigenesis is not a solo act of neoplastic cells, but rather a cooperative process in which...

journal_title：World journal of gastrointestinal oncology

authors： Zhu J,Ding J,Ding F

更新日期：2010-05-15 00:00:00

abstract：:While the incidence and mortality of gastric cancer (GC) have declined due to public health programs, it remains the third deadliest cancer worldwide. For patients with early disease, innovative endoscopic and complex surgical techniques have improved survival. However, for patients with advanced disease, there are li...

journal_title：World journal of gastrointestinal oncology

authors： Lin M,Gao M,Cavnar MJ,Kim J

更新日期：2019-07-15 00:00:00

abstract：:Standard pancreatic resections, such as pancreaticoduodenectomy, distal pancreatectomy, or total pancreatectomy, result in an important loss of normal pancreatic parenchyma and may cause impairment of exocrine and endocrine function. Whilst these procedures are mandatory for malignant tumors, they seem to be too exten...

journal_title：World journal of gastrointestinal oncology

authors： Sperti C,Beltrame V,Milanetto AC,Moro M,Pedrazzoli S

更新日期：2010-06-15 00:00:00

abstract：:Surgical therapy for ulcerative colitis (UC) depends on the medical therapy administered for the patient's condition. UC is a benign disease. However, it has been reported that the rare cases of cancer in UC patients are increasing, and such cases have a worse prognosis. Recently, surgical therapy has greatly changed,...

journal_title：World journal of gastrointestinal oncology

authors： Kinugasa T,Akagi Y

更新日期：2016-04-15 00:00:00

abstract：:In an effort to minimize the limitations of laparoscopy, a robotic surgery system was introduced, but its role for gastric cancer is still unclear. The objective of this article is to assess the current status of robotic surgery for gastric cancer and to predict future prospects. Although the current study was limited...

journal_title：World journal of gastrointestinal oncology

authors： Baek SJ,Lee DW,Park SS,Kim SH

更新日期：2011-10-15 00:00:00

abstract：:Gastric metastases from lung adenocarcinoma are rare. Because gastric metastasis grossly resembles advanced gastric cancer, it is difficult to diagnose gastric metastasis especially when the histology of the primary lung cancer is adenocarcinoma. We describe a case of gastric metastasis from primary lung adenocarcinom...

journal_title：World journal of gastrointestinal oncology

authors： Kim MJ,Hong JH,Park ES,Byun JH

更新日期：2015-03-15 00:00:00

abstract：:Pancreaticobiliary maljunction (PBM) is a high risk factor for biliary tract cancer. In PBM, since the pancreatic duct and bile duct converge outside the duodenal wall beyond the influence of the sphincter of Oddi, pancreatic juice and bile are constantly mixed, producing a variety of harmful substances. Because of th...

journal_title：World journal of gastrointestinal oncology

authors： Tsuchida A,Itoi T

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy has been applied worldwide to improve the survival of patients with gastric adenocarcinoma (GAC). The evaluation of histological regression in primary tumors is valuable for predicting prognosis. However, the prognostic effect of regression change in lymph nodes (LNs) remains unclear...

journal_title：World journal of gastrointestinal oncology

authors： Zhu YL,Sun YK,Xue XM,Yue JY,Yang L,Xue LY

更新日期：2019-01-15 00:00:00

abstract：AIM:To investigate p16 gene methylation and its expression in 30 patients with sporadic colorectal adenocarcinoma in a North Indian population. METHODS:Methylation specific polymerase chain reaction was used to detect p16 gene methylation and immunohistochemistry was used to study the p16 expression in 30 sporadic col...

journal_title：World journal of gastrointestinal oncology

authors： Malhotra P,Kochhar R,Vaiphei K,Wig JD,Mahmood S

更新日期：2010-07-15 00:00:00

abstract：:Gastrointestinal neuroendocrine tumors are rare slow-growing tumors with distinct histological, biological, and clinical characteristics that have increased in incidence and prevalence within the last few decades. They contain chromogranin A, synaptophysin and neuron-specific enolase which are necessary for making a d...

journal_title：World journal of gastrointestinal oncology

authors： Ahmed M

更新日期：2020-08-15 00:00:00

abstract：:Intussusception is a rare condition in the adult population. However, in contrast to its presentation in children, an identifiable etiology is found in the majority of cases. Clinical manifestations of adult intussusception are non-specific and patients may present with acute, intermittent or chronic symptoms, predomi...

journal_title：World journal of gastrointestinal oncology

authors： Nuño-Guzmán CM,Arróniz-Jáuregui J,Espejo I,Solís-Ugalde J,Gómez-Ontiveros JI,Vargas-Gerónimo A,Valle-González J

更新日期：2011-06-15 00:00:00

abstract：BACKGROUND:Radical D2 lymphadenectomy for advanced gastric cancer as a standard procedure has gained global consensus. Mounting studies have shown that the number of lymph nodes dissection directly affects the prognosis and recurrence of gastric cancer. Our previous study showed that there was no obvious lymph node aro...

journal_title：World journal of gastrointestinal oncology

authors： Mu GC,Huang Y,Liu ZM,Chen ZB,Wu XH,Qin XG,Zeng YJ

更新日期：2019-06-15 00:00:00

abstract：BACKGROUND:Regorafenib is an oral small-molecule multikinase inhibitor approved in third or later line of treatment for patients with metastatic colorectal cancer (mCRC). Regorafenib has shown significant benefits in overall survival and progression free survival in two phase III trials compared to placebo in patients ...

journal_title：World journal of gastrointestinal oncology

authors： Ricci V,Granetto C,Falletta A,Paccagnella M,Abbona A,Fea E,Fabozzi T,Lo Nigro C,Merlano MC

更新日期：2020-03-15 00:00:00

abstract：AIM:To identify genetic polymorphisms in the promoter region of the human base excision repair gene NEIL1 in gastric cancer patients. METHODS:The NEIL1 promoter region in DNA from 80 Japanese patients with gastric cancer was searched for genetic polymorphisms by polymerase chain reaction-single-strand conformation pol...

journal_title：World journal of gastrointestinal oncology

authors： Goto M,Shinmura K,Tao H,Tsugane S,Sugimura H

更新日期：2010-02-15 00:00:00

abstract：:Cholangiocarcinoma (CC) arising from the large intrahepatic bile ducts and extrahepatic hilar bile ducts share clinicopathological features and have been called hilar and perihilar CC as a group. However, "hilar and perihilar CC" are also used to refer exclusively to the intrahepatic hilar type CC or, more commonly, t...

journal_title：World journal of gastrointestinal oncology

authors： Castellano-Megías VM,Ibarrola-de Andrés C,Colina-Ruizdelgado F

更新日期：2013-07-15 00:00:00

abstract：:Over the past couple of decades considerable progress has been made in the management of metastatic colorectal cancers (mCRC) leading to a significant improvement in five-year survival. Although part of this success has been rightly attributed to aggressive surgical management and advances in other adjunct treatments,...

journal_title：World journal of gastrointestinal oncology

authors： Pai SG,Fuloria J

更新日期：2016-01-15 00:00:00

abstract：:Because of the aging of the population, prevalence of medical checkups, and advances in imaging studies, the number of pancreatic cystic lesions detected has increased. Once these lesions are detected, neoplastic cysts should be differentiated from non-neoplastic cysts. Furthermore, because of the malignant potential ...

journal_title：World journal of gastrointestinal oncology

authors： Kawaguchi Y,Mine T

更新日期：2016-02-15 00:00:00

abstract：:Gastric cancer is the third leading cause of cancer death worldwide. Even though during these last decades gastric cancer incidence decreased in Western countries, it remains endemic and with a high incidence in Eastern countries. The survival in advanced and metastatic stage of gastric cancer is still very poor. Rece...

journal_title：World journal of gastrointestinal oncology

authors： Satolli MA,Buffoni L,Spadi R,Roato I

更新日期：2015-11-15 00:00:00

abstract：:Pancreatic adenocarcinoma is the fourth cause of cancer-related death in the United States. Surgery is the only potentially curative treatment, but most patients present at diagnosis with unresectable or metastatic disease. Moreover, even with an R0 resection, the majority of patients will die of disease recurrence. M...

journal_title：World journal of gastrointestinal oncology

authors： Sperti C,Moletta L,Merigliano S

更新日期：2015-12-15 00:00:00

abstract：:Despite significant advances in imaging techniques, the incidence of colorectal cancer has been increasing in recent years, with many cases still being diagnosed in advanced stages. Early detection and accurate staging remain the main factors that lead to a decrease in the cost and invasiveness of the curative techniq...

journal_title：World journal of gastrointestinal oncology

authors： Ciocalteu A,Gheonea DI,Saftoiu A,Streba L,Dragoescu NA,Tenea-Cojan TS

更新日期：2018-12-15 00:00:00

abstract：BACKGROUND:Pathological manifestations of hepatic tumours are often associated with prognosis. Although surgical specimens (SS) can provide more information, currently, pre-treatment needle core biopsy (NCB) is increasingly showing important value in understanding the nature of liver tumors and even in diagnosis and tr...

journal_title：World journal of gastrointestinal oncology

authors： Wu JS,Feng JL,Zhu RD,Liu SG,Zhao DW,Li N

更新日期：2019-05-15 00:00:00

abstract：:Pneumo-computed tomography (PnCT) is a technique primarily developed and used to study stenotic lesions of the esophagus, gastroesophageal junction and stomach for pre-surgical planning. It helps to define both upper and lower borders of neoplasms located in the aforementioned areas. It achieves maximum lumen distensi...

journal_title：World journal of gastrointestinal oncology

authors： Ulla M,Gentile E,Yeyati EL,Diez ML,Cavadas D,Garcia-Monaco RD,Ros PR

更新日期：2013-12-15 00:00:00

abstract：BACKGROUND:Due to the special clinical features and biologic characteristics of adolescent and young adult (AYA) cancers, AYA cancers are different from cancers in children and elderly individuals. However, there are few reports on AYA hepatocellular carcinoma (HCC). AIM:To investigate the overall survival (OS) of AYA...

journal_title：World journal of gastrointestinal oncology

authors： Ren J,Tong YM,Cui RX,Wang Z,Li QL,Liu W,Qu K,Zhang JY,Liu C,Wan Y

更新日期：2020-12-15 00:00:00

abstract：:Inflammatory fibroid polyp (IFP) is a rare, idiopathic pseudotumorous lesion of the gastrointestinal tract. While mostly reported as solitary gastric lesions, multiple cases of small bowel IFPs are also reported. It is a documented cause of intussusception in adults. In the case reports of ileal inflammatory fibroid p...

journal_title：World journal of gastrointestinal oncology

authors： Gara N,Falzarano JS,Limm WM,Namiki TS,Tom LK

更新日期：2009-10-15 00:00:00

abstract：AIM:To assess the practice of Egyptian physicians in screening patients for hepatocellular carcinoma (HCC). METHODS:The study included 154 physicians from all over Egypt caring for patients at risk for HCC. The study was based on a questionnaire with 20 items. Each questionnaire consisted of two parts: (1) personal in...

journal_title：World journal of gastrointestinal oncology

authors： Hassany SM,Moustafa EF,Taher ME,Abdeltwab AA,Blum HE

更新日期：2015-09-15 00:00:00

abstract：BACKGROUND:Bile duct cancer constitutes gallbladder cancer (GBC), intrahepatic cholangiocarcinoma (ICA), and extrahepatic cholangiocarcinoma (ECA). These three entities show morphological and immunohistochemical resemblance so that it is difficult to differentiate between primary ICA and liver metastasis of GBC, which ...

journal_title：World journal of gastrointestinal oncology

authors： Inagaki C,Maeda D,Kimura A,Otsuru T,Iwagami Y,Nishida N,Sakai D,Shitotsuki R,Yachida S,Doki Y,Satoh T

更新日期：2019-09-15 00:00:00

abstract：:Colorectal carcinogenesis (CRC) imposes a major health burden in developing countries. It is the third major cause of cancer deaths. Despite several treatment strategies, novel drugs are warranted to reduce the severity of this disease. Adenomatous polyps in the colon are the major culprits in CRC and found in 45% of ...

journal_title：World journal of gastrointestinal oncology

authors： Pandurangan AK,Divya T,Kumar K,Dineshbabu V,Velavan B,Sudhandiran G

更新日期：2018-09-15 00:00:00

abstract：:Peritoneal carcinomatosis (PC) from gastric cancer has traditionally been considered a terminal progression of the disease and is associated with poor survival outcomes. Positive peritoneal cytology similarly worsens the survival of patients with gastric cancer and treatment options for these patients have been limite...

journal_title：World journal of gastrointestinal oncology

authors： Leiting JL,Grotz TE

更新日期：2018-10-15 00:00:00

abstract：:Low rectal cancer is traditionally treated by abdominoperineal resection. In recent years, several new techniques for the treatment of very low rectal cancer patients aiming to preserve the gastrointestinal continuity and to improve both the oncological as well as the functional outcomes, have been emerged. Literature...

journal_title：World journal of gastrointestinal oncology

authors： Dimitriou N,Michail O,Moris D,Griniatsos J

更新日期：2015-07-15 00:00:00