Colorectal carcinogenesis: Insights into the cell death and signal transduction pathways: A review.

abstract：:Laparoscopic and endoscopic cooperative surgery (LECS) is a surgical technique that combines laparoscopic partial gastrectomy and endoscopic submucosal dissection. LECS requires close collaboration between skilled laparoscopic surgeons and experienced endoscopists. For successful LECS, experience alone is not sufficie...

journal_title：World journal of gastrointestinal oncology

authors： Aisu Y,Yasukawa D,Kimura Y,Hori T

更新日期：2018-11-15 00:00:00

abstract：:Most patients treated with curative intent for colorectal cancer (CRC) are included in a follow-up program involving periodic evaluations. The survival benefits of a follow-up program are well delineated, and previous meta-analyses have suggested an overall survival improvement of 5%-10% by intensive follow-up. Howeve...

journal_title：World journal of gastrointestinal oncology

authors： Augestad KM,Rose J,Crawshaw B,Cooper G,Delaney C

更新日期：2014-05-15 00:00:00

abstract：:Pancreaticobiliary maljunction (PBM) is a high risk factor for biliary tract cancer. In PBM, since the pancreatic duct and bile duct converge outside the duodenal wall beyond the influence of the sphincter of Oddi, pancreatic juice and bile are constantly mixed, producing a variety of harmful substances. Because of th...

journal_title：World journal of gastrointestinal oncology

authors： Tsuchida A,Itoi T

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:Breast metastases from colorectal cancer (CRC) are very uncommon. There is no unanimous consensus regarding the best treatment for this rare condition, and management is, especially in elderly patients, limited to diagnosis and palliative care. Capecitabine, an oral fluoropyrimidine derivative, might be help...

journal_title：World journal of gastrointestinal oncology

authors： Taccogna S,Gozzi E,Rossi L,Caruso D,Conte D,Trenta P,Leoni V,Tomao S,Raimondi L,Angelini F

更新日期：2020-09-15 00:00:00

abstract：:While the incidence and mortality of gastric cancer (GC) have declined due to public health programs, it remains the third deadliest cancer worldwide. For patients with early disease, innovative endoscopic and complex surgical techniques have improved survival. However, for patients with advanced disease, there are li...

journal_title：World journal of gastrointestinal oncology

authors： Lin M,Gao M,Cavnar MJ,Kim J

更新日期：2019-07-15 00:00:00

abstract：BACKGROUND:Rectal cancer (RC) is one of the most common diagnosed cancers, and one of the major causes of cancer-related death nowadays. Majority of the current guidelines rely on TNM classification regarding therapy regiments, however recent studies suggest that additional histopathological findings could affect the d...

journal_title：World journal of gastrointestinal oncology

authors： Stojkovic Lalosevic M,Milovanovic T,Micev M,Stojkovic M,Dragasevic S,Stulic M,Rankovic I,Dugalic V,Krivokapic Z,Pavlovic Markovic A

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND:Overexpression of SQSTM1 (sequestosome 1, P62) and nuclear factor-κB (NF-κB) plays an important role in the invasion and metastasis of a variety of malignant tumors. AIM:To explore the expression of P62 and NF-κB in pancreatic cancer and their relationship with clinicopathological features. METHODS:The exp...

journal_title：World journal of gastrointestinal oncology

authors： Zhang ZY,Guo S,Zhao R,Ji ZP,Zhuang ZN

更新日期：2020-07-15 00:00:00

abstract：BACKGROUND:Pathological manifestations of hepatic tumours are often associated with prognosis. Although surgical specimens (SS) can provide more information, currently, pre-treatment needle core biopsy (NCB) is increasingly showing important value in understanding the nature of liver tumors and even in diagnosis and tr...

journal_title：World journal of gastrointestinal oncology

authors： Wu JS,Feng JL,Zhu RD,Liu SG,Zhao DW,Li N

更新日期：2019-05-15 00:00:00

abstract：:Low rectal cancer is traditionally treated by abdominoperineal resection. In recent years, several new techniques for the treatment of very low rectal cancer patients aiming to preserve the gastrointestinal continuity and to improve both the oncological as well as the functional outcomes, have been emerged. Literature...

journal_title：World journal of gastrointestinal oncology

authors： Dimitriou N,Michail O,Moris D,Griniatsos J

更新日期：2015-07-15 00:00:00

abstract：:Pneumo-computed tomography (PnCT) is a technique primarily developed and used to study stenotic lesions of the esophagus, gastroesophageal junction and stomach for pre-surgical planning. It helps to define both upper and lower borders of neoplasms located in the aforementioned areas. It achieves maximum lumen distensi...

journal_title：World journal of gastrointestinal oncology

authors： Ulla M,Gentile E,Yeyati EL,Diez ML,Cavadas D,Garcia-Monaco RD,Ros PR

更新日期：2013-12-15 00:00:00

abstract：:Gastric cancer is the third leading cause of cancer death worldwide. Even though during these last decades gastric cancer incidence decreased in Western countries, it remains endemic and with a high incidence in Eastern countries. The survival in advanced and metastatic stage of gastric cancer is still very poor. Rece...

journal_title：World journal of gastrointestinal oncology

authors： Satolli MA,Buffoni L,Spadi R,Roato I

更新日期：2015-11-15 00:00:00

abstract：:Cholangiocarcinoma (CCA) is a rare cancer arising from the biliary tree with a poor prognosis and limited therapeutic options. Recent large scale molecular characterisation studies have identified recurrent genetic alterations in CCA which may be amenable to therapeutic targeting. In this review we explore the genomic...

journal_title：World journal of gastrointestinal oncology

authors： Kayhanian H,Smyth EC,Braconi C

更新日期：2017-07-15 00:00:00

abstract：:It is well established that colorectal cancer develops from a series of precursor epithelial polyps, including tubular adenomas, villous/tubulovillous adenomas (VA/TVA), sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA). Of these, TSAs are least common and account for only 5% of all serrated poly...

journal_title：World journal of gastrointestinal oncology

authors： Kalimuthu SN,Chelliah A,Chetty R

更新日期：2016-12-15 00:00:00

abstract：BACKGROUND:Kinesin super family 23 (KIF23) is a member of the KIF family, and it plays an important role in mitosis and cytokinesis. Loss of expression can cause mitotic arrest. The Oncomine database is one of the largest oncogene chip databases in the world, and is an integrated data mining platform for cancer gene in...

journal_title：World journal of gastrointestinal oncology

authors： Liang WT,Liu XF,Huang HB,Gao ZM,Li K

更新日期：2020-10-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the second leading cause of cancer mortality worldwide. The cornerstone to improving the prognosis of HCC patients has been the control of loco-regional disease progression and the lesser toxicities of local treatment. Although radiotherapy has not...

journal_title：World journal of gastrointestinal oncology

authors： Hsu CY,Wang CW,Cheng AL,Kuo SH

更新日期：2019-08-15 00:00:00

abstract：:Progress in the molecular oncology of gastrointestinal carcinomas depends on high quality cancer tissues for research. Recent acceleration on new technological platforms as well as the "omics" revolution increases the demands on tissues and peripheral blood for research at the DNA, mRNA and protein levels. Tissue bank...

journal_title：World journal of gastrointestinal oncology

authors： Yu YY,Zhu ZG

更新日期：2010-01-15 00:00:00

abstract：:Pancreatic adenocarcinoma is the fourth cause of cancer-related death in the United States. Surgery is the only potentially curative treatment, but most patients present at diagnosis with unresectable or metastatic disease. Moreover, even with an R0 resection, the majority of patients will die of disease recurrence. M...

journal_title：World journal of gastrointestinal oncology

authors： Sperti C,Moletta L,Merigliano S

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Esophagectomy is a pivotal curative modality for localized esophageal or esophagogastric junction cancer (EC or EJC). Postoperative anastomotic leakage (AL) remains problematic. The use of fibrin sealant (FS) may improve the strength of esophageal anastomosis and reduce the incidence of AL. AIM:To assess th...

journal_title：World journal of gastrointestinal oncology

authors： Lin YB,Fu JH,Huang Y,Hu YH,Luo KJ,Wang KX,Bella AÉ,Situ DR,Chen JY,Lin T,D'Journo XB,Novoa NM,Brunelli A,Fernando HC,Cerfolio RJ,Ismail M,Yang H,AME Thoracic Surgery Collaborative Group.

更新日期：2020-06-15 00:00:00

abstract：AIM:To identify genetic polymorphisms in the promoter region of the human base excision repair gene NEIL1 in gastric cancer patients. METHODS:The NEIL1 promoter region in DNA from 80 Japanese patients with gastric cancer was searched for genetic polymorphisms by polymerase chain reaction-single-strand conformation pol...

journal_title：World journal of gastrointestinal oncology

authors： Goto M,Shinmura K,Tao H,Tsugane S,Sugimura H

更新日期：2010-02-15 00:00:00

abstract：:In an effort to minimize the limitations of laparoscopy, a robotic surgery system was introduced, but its role for gastric cancer is still unclear. The objective of this article is to assess the current status of robotic surgery for gastric cancer and to predict future prospects. Although the current study was limited...

journal_title：World journal of gastrointestinal oncology

authors： Baek SJ,Lee DW,Park SS,Kim SH

更新日期：2011-10-15 00:00:00

abstract：:Over the past ten years, sorafenib, a multikinase inhibitor, has been the standard of care for patients with unresectable hepatocellular carcinoma (HCC) and well-preserved liver function. Recently, lenvatinib, a different multikinase inhibitor, was shown to be non-inferior to sorafenib, in terms of survival, while all...

journal_title：World journal of gastrointestinal oncology

authors： Personeni N,Pressiani T,Bozzarelli S,Rimassa L

更新日期：2019-10-15 00:00:00

abstract：:Digestive endoscopy is currently the main diagnostic procedure for investigation of the digestive tract when a digestive disease is suspected. The use of computers and electronic medical records for the management of endoscopic data are an important key to improving endoscopy unit efficiency and productivity. This tec...

journal_title：World journal of gastrointestinal oncology

authors： Maserat E,Safdari R,Maserat E,Zali MR

更新日期：2012-04-15 00:00:00

abstract：BACKGROUND:Due to the special clinical features and biologic characteristics of adolescent and young adult (AYA) cancers, AYA cancers are different from cancers in children and elderly individuals. However, there are few reports on AYA hepatocellular carcinoma (HCC). AIM:To investigate the overall survival (OS) of AYA...

journal_title：World journal of gastrointestinal oncology

authors： Ren J,Tong YM,Cui RX,Wang Z,Li QL,Liu W,Qu K,Zhang JY,Liu C,Wan Y

更新日期：2020-12-15 00:00:00

abstract：AIM:To examine survival outcomes of perihilar cholangiocarcinoma (PCCA) resection including mortality, morbidity and prognostic factors. METHODS:Multivariate analyses were carried out based on the survival data of all patients with histologically confirmed PCCA who underwent curative resection at Srinagarind Hospital ...

journal_title：World journal of gastrointestinal oncology

authors： Titapun A,Pugkhem A,Luvira V,Srisuk T,Somintara O,Saeseow OT,Sripanuskul A,Nimboriboonporn A,Thinkhamrop B,Khuntikeo N

更新日期：2015-12-15 00:00:00

abstract：AIM:To investigate p16 gene methylation and its expression in 30 patients with sporadic colorectal adenocarcinoma in a North Indian population. METHODS:Methylation specific polymerase chain reaction was used to detect p16 gene methylation and immunohistochemistry was used to study the p16 expression in 30 sporadic col...

journal_title：World journal of gastrointestinal oncology

authors： Malhotra P,Kochhar R,Vaiphei K,Wig JD,Mahmood S

更新日期：2010-07-15 00:00:00

abstract：BACKGROUND:Epstein-Barr virus (EBV)-associated carcinoma is a gastric cancer subtype with a morphology characterized by gastric carcinoma with lymphoid stroma (GCLS). Clinicopathological studies have indicated a better prognosis for GCLS than for common gastric carcinomas. Some previous cases of early gastric cancer as...

journal_title：World journal of gastrointestinal oncology

authors： Kobayashi Y,Kunogi T,Tanabe H,Murakami Y,Iwama T,Sasaki T,Takahashi K,Ando K,Nomura Y,Ueno N,Kashima S,Moriichi K,Takei H,Fujiya M,Okumura T

更新日期：2019-10-15 00:00:00

abstract：:Intussusception is a rare condition in the adult population. However, in contrast to its presentation in children, an identifiable etiology is found in the majority of cases. Clinical manifestations of adult intussusception are non-specific and patients may present with acute, intermittent or chronic symptoms, predomi...

journal_title：World journal of gastrointestinal oncology

authors： Nuño-Guzmán CM,Arróniz-Jáuregui J,Espejo I,Solís-Ugalde J,Gómez-Ontiveros JI,Vargas-Gerónimo A,Valle-González J

更新日期：2011-06-15 00:00:00

abstract：BACKGROUND:In recent years, intraoperative radiotherapy (IORT) has been increasingly used for the treatment of rectal cancer. However, the efficacy and safety of IORT for the treatment of rectal cancer are still controversial. AIM:To evaluate the value of IORT for patients with rectal cancer. METHODS:We searched PubM...

journal_title：World journal of gastrointestinal oncology

authors： Liu B,Ge L,Wang J,Chen YQ,Ma SX,Ma PL,Zhang YQ,Yang KH,Cai H

更新日期：2021-01-15 00:00:00

abstract：:Inflammatory fibroid polyp (IFP) is a rare, idiopathic pseudotumorous lesion of the gastrointestinal tract. While mostly reported as solitary gastric lesions, multiple cases of small bowel IFPs are also reported. It is a documented cause of intussusception in adults. In the case reports of ileal inflammatory fibroid p...

journal_title：World journal of gastrointestinal oncology

authors： Gara N,Falzarano JS,Limm WM,Namiki TS,Tom LK

更新日期：2009-10-15 00:00:00

abstract：:Because of the aging of the population, prevalence of medical checkups, and advances in imaging studies, the number of pancreatic cystic lesions detected has increased. Once these lesions are detected, neoplastic cysts should be differentiated from non-neoplastic cysts. Furthermore, because of the malignant potential ...

journal_title：World journal of gastrointestinal oncology

authors： Kawaguchi Y,Mine T

更新日期：2016-02-15 00:00:00