Abstract:
AIM:To examine survival outcomes of perihilar cholangiocarcinoma (PCCA) resection including mortality, morbidity and prognostic factors. METHODS:Multivariate analyses were carried out based on the survival data of all patients with histologically confirmed PCCA who underwent curative resection at Srinagarind Hospital from January 2006 to December 2011. RESULTS:There were 29 (19%) cases of intrahepatic CCA that involved hilar and 124 (81%) with hilar bile-duct cancer. R0 resection was carried out on 66 (43.1%) patients of whom 50 (32.7%) also had lymph node metastasis. The other patients underwent R1 resection. The overall 5-year survival rate was 20.6% (95%CI: 13.8-28.4) and median survival time was 19.9 mo. Postoperative mortality was 2%, and 30% of patients had complications. Patients without lymph node metastasis were 60% less likely to die than those with metastasis. Achieving R0 led to a 58% reduction in the chance of mortality as compared to R1. CONCLUSION:To achieve a better survival outcome, focus should center on performing radical surgery and detection of patients with early stage cancer.
journal_name
World J Gastrointest Oncoljournal_title
World journal of gastrointestinal oncologyauthors
Titapun A,Pugkhem A,Luvira V,Srisuk T,Somintara O,Saeseow OT,Sripanuskul A,Nimboriboonporn A,Thinkhamrop B,Khuntikeo Ndoi
10.4251/wjgo.v7.i12.503subject
Has Abstractpub_date
2015-12-15 00:00:00pages
503-12issue
12issn
1948-5204journal_volume
7pub_type
杂志文章abstract:BACKGROUND:Radical D2 lymphadenectomy for advanced gastric cancer as a standard procedure has gained global consensus. Mounting studies have shown that the number of lymph nodes dissection directly affects the prognosis and recurrence of gastric cancer. Our previous study showed that there was no obvious lymph node aro...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v11.i6.499
更新日期:2019-06-15 00:00:00
abstract::Hepatocellular carcinoma (HCC) is a highly malignant tumor and extrahepatic metastasis is not rare. The most common organ of HCC metastasis is lung, followed by bone and adrenal gland. To the best of our knowledge, isolated pancreatic metastasis of HCC that developed after curative resection has not been described pre...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v2.i4.209
更新日期:2010-04-15 00:00:00
abstract::Inflammatory fibroid polyp (IFP) is a rare, idiopathic pseudotumorous lesion of the gastrointestinal tract. While mostly reported as solitary gastric lesions, multiple cases of small bowel IFPs are also reported. It is a documented cause of intussusception in adults. In the case reports of ileal inflammatory fibroid p...
journal_title:World journal of gastrointestinal oncology
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doi:10.4251/wjgo.v1.i1.89
更新日期:2009-10-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
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abstract::Paraneoplastic leukemoid reaction is a rare syndrome defined by a leukocyte count exceeding 50 Giga/Liter (G/L), mostly described with progressive lung or renal carcinoma. We report a case of a 68-year-old man with recurrent pancreatic carcinoma presenting a leukemoid reaction with a white blood cell count of 63.87 G/...
journal_title:World journal of gastrointestinal oncology
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journal_title:World journal of gastrointestinal oncology
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
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journal_title:World journal of gastrointestinal oncology
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更新日期:2019-02-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
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更新日期:2010-06-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
pub_type: 社论
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更新日期:2018-10-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
pub_type: 临床试验
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更新日期:2020-06-15 00:00:00
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pub_type: 杂志文章
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更新日期:2013-07-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
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journal_title:World journal of gastrointestinal oncology
pub_type:
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更新日期:2019-10-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
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更新日期:2016-12-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
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更新日期:2019-07-15 00:00:00
abstract::Colorectal cancer is the second leading cause of death from cancer among adults. The disease begins as a benign adenomatous polyp, which develops into an advanced adenoma with high-grade dysplasia and then progresses to an invasive cancer. Appropriate apoptotic signaling is fundamentally important to preserve a health...
journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
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更新日期:2016-08-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
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journal_title:World journal of gastrointestinal oncology
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journal_title:World journal of gastrointestinal oncology
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更新日期:2015-12-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
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更新日期:2020-11-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
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更新日期:2014-05-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v1.i1.26
更新日期:2009-10-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
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更新日期:2011-06-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章,评审
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更新日期:2019-08-15 00:00:00
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journal_title:World journal of gastrointestinal oncology
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journal_title:World journal of gastrointestinal oncology
pub_type: 杂志文章
doi:10.4251/wjgo.v4.i4.76
更新日期:2012-04-15 00:00:00
abstract::Over the past ten years, sorafenib, a multikinase inhibitor, has been the standard of care for patients with unresectable hepatocellular carcinoma (HCC) and well-preserved liver function. Recently, lenvatinib, a different multikinase inhibitor, was shown to be non-inferior to sorafenib, in terms of survival, while all...
journal_title:World journal of gastrointestinal oncology
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更新日期:2019-10-15 00:00:00