解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Use of standardized and scientifically sound outcome measures is encouraged in clinical practice and research. With the development of newer rehabilitation therapies, we need technology-supported upper extremity outcome measures that are easily accessible, reliable and valid. 3-Dimensional printing (3D-print...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-020-00839-3
更新日期:2021-01-05 00:00:00
abstract:BACKGROUND:Instrumented pendulum test is an objective and repeatable biomechanical method of assessment for spasticity. However, multitude of sensor technologies and plenty of suggested outcome measures, confuse those interested in implementing this method in practice. Lack of a standard agreement on the definition of ...
journal_title:Biomedical engineering online
pub_type: 杂志文章,评审
doi:10.1186/s12938-020-00826-8
更新日期:2020-11-09 00:00:00
abstract::Delivering short trains of electric pulses to the muscles and nerves can elicit action potentials resulting in muscle contractions. When the stimulations are sequenced to generate functional movements, such as grasping or walking, the application is referred to as functional electrical stimulation (FES). Implications ...
journal_title:Biomedical engineering online
pub_type: 杂志文章,评审
doi:10.1186/s12938-020-00824-w
更新日期:2020-11-04 00:00:00
abstract::Advances in biomaterials and the need for patient-specific bone scaffolds require modern manufacturing approaches in addition to a design strategy. Hybrid materials such as those with functionally graded properties are highly needed in tissue replacement and repair. However, their constituents, proportions, sizes, con...
journal_title:Biomedical engineering online
pub_type: 杂志文章,评审
doi:10.1186/s12938-020-00810-2
更新日期:2020-09-03 00:00:00
abstract:BACKGROUND:Nonnegative matrix factorization (NMF) has been successfully used for electroencephalography (EEG) spectral analysis. Since NMF was proposed in the 1990s, many adaptive algorithms have been developed. However, the performance of their use in EEG data analysis has not been fully compared. Here, we provide a c...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-020-00796-x
更新日期:2020-07-31 00:00:00
abstract:BACKGROUND:Advances in transcranial electrical stimulation (tES) are hampered by the conventional rubber electrodes manually attached to the head with rubber bands. This procedure limits montages to a few electrodes, is error prone with respect to electrode configurations and is burdensome for participants and operator...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-020-00792-1
更新日期:2020-06-17 00:00:00
abstract:BACKGROUND:STAR is a model-based, personalised, risk-based dosing approach for glycaemic control (GC) in critically ill patients. STAR provides safe, effective control to nearly all patients, using 1-3 hourly measurement and intervention intervals. However, the average 11-12 measurements per day required can be a clini...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-020-00771-6
更新日期:2020-04-29 00:00:00
abstract:BACKGROUND:Reach-grasp movements are motor components commonly affected after stroke and directly related to the independence of these individuals. Evaluations of these activities can be performed using clinical instruments and assessed by detailed and costly kinematic analyses. The aim of this study was to develop an ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-020-0758-7
更新日期:2020-03-04 00:00:00
abstract::The Editors-in-Chief have retracted this article [1] because, after publication, concerns were raised regarding the study design and statistical analysis. Post-publication review has confirmed firstly that within-group changes were highlighted rather than between-group differences as appropriate for a randomized trial...
journal_title:Biomedical engineering online
pub_type: 杂志文章,撤回出版物
doi:10.1186/s12938-020-0749-8
更新日期:2020-01-24 00:00:00
abstract:BACKGROUND:Bone is a hierarchically structured composite material, and different hierarchical levels exhibit diverse material properties and functions. The stress and strain distribution and fluid flow in bone play an important role in the realization of mechanotransduction and bone remodeling. METHODS:To investigate ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0741-3
更新日期:2019-12-23 00:00:00
abstract:BACKGROUND:Xenogeneic bone has been widely used in a variety of clinical bone-related disease to promote bone healing and restore bone defects. However, the adverse effects of immune system limit its application in the clinic. The aim of this study was to evaluate xenogeneic bone safety of immunotoxicity and explore th...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0729-z
更新日期:2019-11-14 00:00:00
abstract:BACKGROUND:The challenges of glycaemic control in critically ill patients have been debated for 20 years. While glycaemic control shows benefits inter- and intra-patient metabolic variability results in increased hypoglycaemia and glycaemic variability, both increasing morbidity and mortality. Hence, current recommenda...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0720-8
更新日期:2019-10-22 00:00:00
abstract::It was highlighted that the original article [1] contained an error in the Acknowledgments section. ...
journal_title:Biomedical engineering online
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12938-019-0707-5
更新日期:2019-08-08 00:00:00
abstract:BACKGROUND:Electrical impedance tomography (EIT) has been used for functional lung imaging of regional air distributions during mechanical ventilation in intensive care units (ICU). From numerous clinical and animal studies focusing on specific lung functions, a consensus about how to use the EIT technique has been for...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0701-y
更新日期:2019-07-25 00:00:00
abstract:BACKGROUND:The use of flow-diverters for non-saccular cerebral posterior circulation aneurysms requires complex deployment techniques and is associated with high mortality and morbidity. Therefore, further studies are required to clarify the effect of stenting on post-treatment hemodynamics in such aneurysms. In this s...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0699-1
更新日期:2019-07-24 00:00:00
abstract::It was highlighted that the original article [1] had an omission in the Abstract. This Correction article shows the omitted sentence: "This article [1] was awarded the SIAMOC Best Methodological Paper 2018". ...
journal_title:Biomedical engineering online
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12938-019-0698-2
更新日期:2019-07-23 00:00:00
abstract:PURPOSE:We propose a collaborative and secure transmission scheme in order to safely and efficiently transmit medical data and provide telemedicine services, lighten the load on wireless access networks, and improve the quality of medical treatment such as surgery. METHODS:First, the transmission technology based on o...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0674-x
更新日期:2019-05-20 00:00:00
abstract:BACKGROUND:Biomechanical and clinical parameters contribute very closely to functional evaluations of the knee joint. To better understand knee osteoarthritis joint function, the association between a set of knee biomechanical data and a set of clinical parameters of an osteoarthritis population (OA) is investigated in...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0676-8
更新日期:2019-05-15 00:00:00
abstract:BACKGROUND:Irrigation is considered to be a critical part of root canal treatment. However, little is known about the effect of needle movement on the irrigation process. Therefore, this study aimed to investigate the influence of the syringe and needle movement on root canal irrigation using a three-dimensional comput...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0679-5
更新日期:2019-05-06 00:00:00
abstract:BACKGROUND:Although use of a dynamic hip screw (DHS) for stable intertrochanteric hip fracture fixation has been successfully applied in fracture healing for more than 20 years, DHS fixation on unstable intertrochanteric fractures still has a high failure rate, especially in patients with osteoporosis. Although the wir...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0663-0
更新日期:2019-04-24 00:00:00
abstract:BACKGROUND:The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the processing of descending efferent neural signals recorded using peripheral neural interfaces could be a solution to such limitation. Unfortunately, this choic...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0659-9
更新日期:2019-04-08 00:00:00
abstract:BACKGROUND:Entropy analysis has been attracting increasing attentions in the recent two or three decades. It assesses complexity, or irregularity, of time-series which is extraordinarily relevant to physiology and diseases as demonstrated by tremendous studies. However, the complexity can hardly be appreciated by tradi...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0650-5
更新日期:2019-03-20 00:00:00
abstract:BACKGROUND:Non-contact tonometers based on the method using air puff and Scheimpflug's fast camera are one of the latest devices allowing the measurement of intraocular pressure and additional biomechanical parameters of the cornea. Biomechanical features significantly affect changes in intraocular pressure values, as ...
journal_title:Biomedical engineering online
pub_type: 杂志文章,评审
doi:10.1186/s12938-019-0636-3
更新日期:2019-02-13 00:00:00
abstract:BACKGROUND:Quantizing the Breast Imaging Reporting and Data System (BI-RADS) criteria into different categories with the single ultrasound modality has always been a challenge. To achieve this, we proposed a two-stage grading system to automatically evaluate breast tumors from ultrasound images into five categories bas...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0626-5
更新日期:2019-01-24 00:00:00
abstract:BACKGROUND:Optical imaging is one of the most common, low-cost imaging tools used for investigating the tumor biological behavior in vivo. This study explores the feasibility and sensitivity of a near infrared fluorescent protein mKate2 for a long-term non-invasive tumor imaging in BALB/c nude mice, by using a low-powe...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0615-0
更新日期:2018-12-29 00:00:00
abstract:BACKGROUND:Mobile health apps (mHealth apps) are increasing in popularity and utility for the management of many chronic diseases. Although the current reimbursement structure for mHealth apps is lagging behind the rapidly improving functionality, more clinicians will begin to recommend these apps as they prove their c...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0611-4
更新日期:2018-12-17 00:00:00
abstract:BACKGROUND:This paper proposes a methodology for helping bridge the gap between the complex waveform information frequently available in an intensive care unit and the simple, lumped values favoured for rapid clinical diagnosis and management. This methodology employs a simple waveform contour analysis approach to comp...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0603-4
更新日期:2018-11-20 00:00:00
abstract:BACKGROUND:Biomedical named entity recognition (Bio-NER) is a fundamental task in handling biomedical text terms, such as RNA, protein, cell type, cell line, and DNA. Bio-NER is one of the most elementary and core tasks in biomedical knowledge discovery from texts. The system described here is developed by using the Bi...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0573-6
更新日期:2018-11-06 00:00:00
abstract:BACKGROUND:The anterior cruciate ligament (ACL) plays an important role in stabilizing translation and rotation of the tibia relative to the femur. ACL injury alters knee kinematics and usually links to the alternation of gait patterns. The aim of this study is to develop a new method to distinguish between gait patter...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0594-1
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:In cochlear implants (CI) measuring the electrically evoked compound action potential (ECAP) has become an important tool for verifying the electrode-nerve interface as well as establishing a basis for a map to program the speech processor. In a standard clinical setup recordings are averaged over 25-100 rep...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0588-z
更新日期:2018-10-19 00:00:00
abstract:BACKGROUND:Wound healing of retinal pigment epithelium (RPE) is a complex process that may take place in common age-related macular degeneration eye disease. The purpose of this study was to evaluate whether wounding and wound healing has an effect on Ca2+ dynamics in human embryonic stem cell (hESC)-RPEs cultured diff...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0535-z
更新日期:2018-07-31 00:00:00
abstract:BACKGROUND:Mitral valve failure can require repair or replacement. Replacement bioprosthetic valves are treated with glutaraldehyde prior to implantation. The aim of this study was to determine the changes in mechanical properties following glutaraldehyde fixation of mitral valve chordae. METHODS:To investigate the im...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0524-2
更新日期:2018-07-13 00:00:00
abstract:BACKGROUND:The paper presents an approach and computer-aided method of numerical evaluation of the quality of porous membranes used as scaffolds for cultivation of chondrocytes in regeneration of biological tissues. MATERIALS:The scanning electron microscope (SEM) images of 300× and 1000× magnification presenting the ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0481-9
更新日期:2018-05-30 00:00:00
abstract:BACKGROUND:Computational modeling of cardiovascular flow is a growing and useful field, but such simulations usually require the researcher to guess the flow's inlet and outlet conditions since they are difficult and expensive to measure. It is critical to determine the amount of uncertainty introduced by these assumpt...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0497-1
更新日期:2018-05-30 00:00:00
abstract:BACKGROUND:Peripheral ECMO is an effective cardiopulmonary support in clinical. The perfusion level could directly influence the performances and complications. However, there are few studies on the effects of the perfusion level on hemodynamics of peripheral ECMO. METHODS:The geometric model of cardiovascular system ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0493-5
更新日期:2018-05-09 00:00:00
abstract:BACKGROUND:Many studies have demonstrated that the geometry of the carotid bifurcation enables prediction of blood flow variation associated with atherosclerotic plaque formation. The phase angle between the arterial wall circumferential strain and its instantaneous wall shear stress is known as stress phase angle (SPA...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0458-8
更新日期:2018-03-02 00:00:00
abstract:BACKGROUND:Image segmentation is an essential and non trivial task in computer vision and medical image analysis. Computed tomography (CT) is one of the most accessible medical examination techniques to visualize the interior of a patient's body. Among different computer-aided diagnostic systems, the applications dedic...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0456-x
更新日期:2018-02-27 00:00:00
abstract:BACKGROUND:The QRS complex is the most noticeable feature in the electrocardiogram (ECG) signal, therefore, its detection is critical for ECG signal analysis. The existing detection methods largely depend on hand-crafted manual features and parameters, which may introduce significant computational complexity, especiall...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0441-4
更新日期:2018-01-29 00:00:00
abstract:BACKGROUND:Colonoscopy plays an important role in the clinical screening and management of colorectal cancer. The traditional 'see one, do one, teach one' training style for such invasive procedure is resource intensive and ineffective. Given that colonoscopy is difficult, and time-consuming to master, the use of virtu...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0433-4
更新日期:2018-01-25 00:00:00
abstract:BACKGROUND:Red blood cells (RBCs) deform significantly and repeatedly when passing through narrow capillaries and delivering dioxygen throughout the body. Deformability of RBCs is a key characteristic, largely governed by the mechanical properties of the cell membrane. This study investigated RBC mechanical properties ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-017-0429-5
更新日期:2017-12-19 00:00:00