Abstract：
:Advances in biomaterials and the need for patient-specific bone scaffolds require modern manufacturing approaches in addition to a design strategy. Hybrid materials such as those with functionally graded properties are highly needed in tissue replacement and repair. However, their constituents, proportions, sizes, configurations and their connection to each other are a challenge to manufacturing. On the other hand, various bone defect sizes and sites require a cost-effective readily adaptive manufacturing technique to provide components (scaffolds) matching with the anatomical shape of the bone defect. Additive manufacturing or three-dimensional (3D) printing is capable of fabricating functional physical components with or without porosity by depositing the materials layer-by-layer using 3D computer models. Therefore, it facilitates the production of advanced bone scaffolds with the feasibility of making changes to the model. This review paper first discusses the development of a computer-aided-design (CAD) approach for the manufacture of bone scaffolds, from the anatomical data acquisition to the final model. It also provides information on the optimization of scaffold's internal architecture, advanced materials, and process parameters to achieve the best biomimetic performance. Furthermore, the review paper describes the advantages and limitations of 3D printing technologies applied to the production of bone tissue scaffolds.
journal_name
Biomed Eng Onlinejournal_title
Biomedical engineering onlineauthors
Bahraminasab Mdoi
10.1186/s12938-020-00810-2subject
Has Abstractpub_date
2020-09-03 00:00:00pages
69issue
1issn
1475-925Xpii
10.1186/s12938-020-00810-2journal_volume
19pub_type
杂志文章,评审abstract：BACKGROUND:The subjects in EEG-Brain computer interface (BCI) system experience difficulties when attempting to obtain the consistent performance of the actual movement by motor imagery alone. It is necessary to find the optimal conditions and stimuli combinations that affect the performance factors of the EEG-BCI syst...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-91
更新日期：2011-10-12 00:00:00
abstract：BACKGROUND:Peripheral ECMO is an effective cardiopulmonary support in clinical. The perfusion level could directly influence the performances and complications. However, there are few studies on the effects of the perfusion level on hemodynamics of peripheral ECMO. METHODS:The geometric model of cardiovascular system ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0493-5
更新日期：2018-05-09 00:00:00
abstract：BACKGROUND:Mitral valve failure can require repair or replacement. Replacement bioprosthetic valves are treated with glutaraldehyde prior to implantation. The aim of this study was to determine the changes in mechanical properties following glutaraldehyde fixation of mitral valve chordae. METHODS:To investigate the im...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0524-2
更新日期：2018-07-13 00:00:00
abstract：BACKGROUND:Heart rate can be used to prescribe exercise intensity for development and maintenance of cardiorespiratory fitness. The aim of this study was to identify the dynamics of heart rate response during moderate-to-vigorous treadmill exercise and to explore parameter dependencies with respect to time, intensity l...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-015-0112-7
更新日期：2015-12-21 00:00:00
abstract：BACKGROUND:Biomedical named entity recognition (Bio-NER) is a fundamental task in handling biomedical text terms, such as RNA, protein, cell type, cell line, and DNA. Bio-NER is one of the most elementary and core tasks in biomedical knowledge discovery from texts. The system described here is developed by using the Bi...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0573-6
更新日期：2018-11-06 00:00:00
abstract：BACKGROUND:The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the processing of descending efferent neural signals recorded using peripheral neural interfaces could be a solution to such limitation. Unfortunately, this choic...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-019-0659-9
更新日期：2019-04-08 00:00:00
abstract：:It was highlighted that the original article [1] contained an error in the Acknowledgments section. ...
journal_title：Biomedical engineering online
pub_type： 杂志文章,已发布勘误
doi：10.1186/s12938-019-0707-5
更新日期：2019-08-08 00:00:00
abstract：BACKGROUND:A common but debated technique in the management of swallowing difficulties is the chin tuck swallow, where the neck is flexed forward prior to swallowing. Natural variations in chin tuck angles across individuals may contribute to the differential effectiveness of the technique. METHODOLOGY:To facilitate t...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-8-25
更新日期：2009-10-07 00:00:00
abstract：BACKGROUND:Falls can cause trauma, disability and death among older people. Ambulatory accelerometer devices are currently capable of detecting falls in a controlled environment. However, research suggests that most current approaches can tend to have insufficient sensitivity and specificity in non-laboratory environme...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-11-9
更新日期：2012-02-16 00:00:00
abstract：BACKGROUND:Recent studies indicate that the blue-yellow colour discrimination is impaired in ADHD individuals. However, the relationship between colour and performance has not been investigated. This paper describes the development and the testing of a virtual environment that is capable to quantify the influence of re...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-74
更新日期：2011-08-19 00:00:00
abstract：BACKGROUND:In cochlear implants (CI) measuring the electrically evoked compound action potential (ECAP) has become an important tool for verifying the electrode-nerve interface as well as establishing a basis for a map to program the speech processor. In a standard clinical setup recordings are averaged over 25-100 rep...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0588-z
更新日期：2018-10-19 00:00:00
abstract：BACKGROUND:Atherosclerosis causes millions of deaths, annually yielding billions in expenses round the world. Intravascular Optical Coherence Tomography (IVOCT) is a medical imaging modality, which displays high resolution images of coronary cross-section. Nonetheless, quantitative information can only be obtained with...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-78
更新日期：2013-08-09 00:00:00
abstract：BACKGROUND:To determine how the mechanical property and micro structure affect tissue regeneration and angiogenesis, three types of scaffolds were studied. Acellular dermal matrices (ADM), produced from human skin by removing the epidermis and cells, has been widely used in wound healing because of its high mechanical ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-125
更新日期：2013-12-04 00:00:00
abstract：BACKGROUND AND AIMS:People with internet addiction (IA) suffer from mental, physical, social, and occupational problems. IA includes psychological and physiological syndromes, and among the syndromes, emotion was suggested important mental and physiological expressions of IA. However, few physiologically emotional char...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0201-2
更新日期：2016-07-04 00:00:00
abstract：BACKGROUND:Neural stimulation is an important method used to activate or inhibit action potentials of the neuronal anatomical targets found in the brain, central nerve and peripheral nerve. The neural stimulator system produces biphasic pulses that deliver balanced charge into tissue from single or multichannel electro...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-017-0385-0
更新日期：2017-08-14 00:00:00
abstract：BACKGROUND:Speech production and speech phonetic features gradually improve in children by obtaining audio feedback after cochlear implantation or using hearing aids. The aim of this study was to develop and evaluate automated classification of voice disorder in children with cochlear implantation and hearing aids. ME...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-3
更新日期：2011-01-14 00:00:00
abstract：BACKGROUND:In order to characterize the intracranial pressure-volume reserve capacity, the correlation coefficient (R) between the ICP wave amplitude (A) and the mean ICP level (P), the RAP index, has been used to improve the diagnostic value of ICP monitoring. Baseline pressure errors (BPEs), caused by spontaneous shi...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-99
更新日期：2014-07-23 00:00:00
abstract：BACKGROUND:The paper presents an approach and computer-aided method of numerical evaluation of the quality of porous membranes used as scaffolds for cultivation of chondrocytes in regeneration of biological tissues. MATERIALS:The scanning electron microscope (SEM) images of 300× and 1000× magnification presenting the ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0481-9
更新日期：2018-05-30 00:00:00
abstract：:A comment on G. Litscher: Infrared thermography fails to visualize stimulation-induced meridian-like structures. Biomed. Eng. OnLine 2005, 4:38 (15 June 2005), with a response by the author. ...
journal_title：Biomedical engineering online
pub_type： 评论,信件
doi：10.1186/1475-925X-10-80
更新日期：2011-09-11 00:00:00
abstract：OBJECTIVE:The purpose of this study was to show the effects of the tracheal gas insufflation (TGI) technique on gas exchange using helium-oxygen mixtures during high-frequency oscillatory ventilation (HFOV). We hypothesized that a helium-oxygen mixture delivered into the trachea using the TGI technique (0.3 L/min) woul...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-29
更新日期：2013-04-08 00:00:00
abstract：OBJECTIVE:Heart rate variability (HRV) analysis, which is an important tool for activity assessment of the cardiac autonomic nervous system, very often includes the estimation of power spectra for series of interbeat intervals (IBI). Ectopic beats and artifacts have a destructive effect on the standard methods (Fourier...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-138
更新日期：2014-09-23 00:00:00
abstract：BACKGROUND:Routine vascular surgery operations involve stitching of disconnected human arteries with themselves or with artificial grafts (arterial anastomosis). This study aims to extend current knowledge and provide better-substantiated understanding of the mechanics of end-to-end anastomosis through the development ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-14-1
更新日期：2015-01-06 00:00:00
abstract：BACKGROUND:Quantizing the Breast Imaging Reporting and Data System (BI-RADS) criteria into different categories with the single ultrasound modality has always been a challenge. To achieve this, we proposed a two-stage grading system to automatically evaluate breast tumors from ultrasound images into five categories bas...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-019-0626-5
更新日期：2019-01-24 00:00:00
abstract：BACKGROUND:Gait analysis and research have been developed to obtain characteristics of movement patterns of people while walking. However, traditional measuring systems present different drawbacks that reduce their use and application. Among those drawbacks one can find: high price, low sampling frequency and limiting ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-34
更新日期：2014-03-31 00:00:00
abstract：BACKGROUND:Studies found that treatment symptoms of concern to oncology/hematology patients were greatly under-identified in medical records. On average, 11.0 symptoms were reported of concern to patients compared to 1.5 symptoms identified in their medical records. A solution to this problem is use of an electronic sy...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-14-S2-S1
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:In ultrasound imaging systems, the digital transmit beamformer is a critical module that generates accurate control over several transmission parameters. However, such transmit front-end module is not typically accessible to ultrasound researchers. To overcome this difficulty, we have been developing a compa...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-24
更新日期：2013-03-20 00:00:00
abstract：:The Editors-in-Chief have retracted this article [1] because, after publication, concerns were raised regarding the study design and statistical analysis. Post-publication review has confirmed firstly that within-group changes were highlighted rather than between-group differences as appropriate for a randomized trial...
journal_title：Biomedical engineering online
pub_type： 杂志文章,撤回出版物
doi：10.1186/s12938-020-0749-8
更新日期：2020-01-24 00:00:00
abstract：BACKGROUND:Mobile health apps (mHealth apps) are increasing in popularity and utility for the management of many chronic diseases. Although the current reimbursement structure for mHealth apps is lagging behind the rapidly improving functionality, more clinicians will begin to recommend these apps as they prove their c...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0611-4
更新日期：2018-12-17 00:00:00
abstract：BACKGROUND:The QRS complex is the most noticeable feature in the electrocardiogram (ECG) signal, therefore, its detection is critical for ECG signal analysis. The existing detection methods largely depend on hand-crafted manual features and parameters, which may introduce significant computational complexity, especiall...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0441-4
更新日期：2018-01-29 00:00:00
abstract：BACKGROUND:Irrigation is considered to be a critical part of root canal treatment. However, little is known about the effect of needle movement on the irrigation process. Therefore, this study aimed to investigate the influence of the syringe and needle movement on root canal irrigation using a three-dimensional comput...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-019-0679-5
更新日期：2019-05-06 00:00:00
