Abstract：
OBJECTIVE:The purpose of this study was to show the effects of the tracheal gas insufflation (TGI) technique on gas exchange using helium-oxygen mixtures during high-frequency oscillatory ventilation (HFOV). We hypothesized that a helium-oxygen mixture delivered into the trachea using the TGI technique (0.3 L/min) would enhance gas exchange during HFOV. METHODS:Three rabbits were prepared and ventilated by HFOV with carrier 70% helium/oxygen or 70% nitrogen/oxygen gas mixture with TGI in a crossover study. Changing the gas mixture from nitrogen70% to helium70% and back was performed three times per animal with constant ventilation parameters. RESULTS:Compared with the nitrogen-oxygen mixture, the helium-oxygen mixture of TGI reduced PaCO2 by 7.6 mmHg (p < 0.01) and improved PaO2 by 14 mmHg (p < 0.01). Amplitude during TGI was significantly lower with the helium-oxygen mixture than with the nitrogen-oxygen mixture (p < 0.01) and did not significantly affect mean airway pressure. CONCLUSIONS:This study demonstrated that a helium-oxygen mixture delivered into the trachea using the TGI technique would enhance CO2 elimination and improve oxygenation during HFOV.
journal_name
Biomed Eng Onlinejournal_title
Biomedical engineering onlineauthors
Baba A,Nakamura T,Aikawa T,Koike Kdoi
10.1186/1475-925X-12-29subject
Has Abstractpub_date
2013-04-08 00:00:00pages
29issn
1475-925Xpii
1475-925X-12-29journal_volume
12pub_type
杂志文章abstract：BACKGROUND:Since the first well-known electrocardiogram (ECG) delineator based on Wavelet Transform (WT) presented by Li et al. in 1995, a significant research effort has been devoted to the exploitation of this promising method. Its ability to reliably delineate the major waveform components (mono- or bi-phasic P wave...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-23
更新日期：2011-04-03 00:00:00
abstract：BACKGROUND:Falls can cause trauma, disability and death among older people. Ambulatory accelerometer devices are currently capable of detecting falls in a controlled environment. However, research suggests that most current approaches can tend to have insufficient sensitivity and specificity in non-laboratory environme...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-11-9
更新日期：2012-02-16 00:00:00
abstract：BACKGROUND:For electroporation-based therapies, accurate modeling of the electric field distribution within the target tissue is important for predicting the treatment volume. In response to conventional, unipolar pulses, the electrical impedance of a tissue varies as a function of the local electric field, leading to ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-14-S3-S3
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:In order to reduce the radiation dose of CT (computed tomography), compressed sensing theory has been a hot topic since it provides the possibility of a high quality recovery from the sparse sampling data. Recently, the algorithm based on DL (dictionary learning) was developed to deal with the sparse CT reco...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0193-y
更新日期：2016-06-18 00:00:00
abstract：BACKGROUND:It is generally accepted that cartilage adaptation and degeneration are mechanically mediated. Investigating the swelling behaviour of cartilage is important because the stress and strain state of cartilage is associated with the swelling and deformation behaviour. It is well accepted that the swelling of so...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925x-1-8
更新日期：2002-12-19 00:00:00
abstract：BACKGROUND:The extracellular matrix (ECM) provides a supportive microenvironment for cells, which is suitable as a tissue engineering scaffold. Mechanical stimulus plays a significant role in the fate of osteoblast, suggesting that it regulates ECM formation. Therefore, we investigated the influence of mechanical stimu...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-11-80
更新日期：2012-10-25 00:00:00
abstract：BACKGROUND:Phase contrast magnetic resonance imaging (PC-MRI) is used clinically for quantitative assessment of cardiovascular flow and function, as it is capable of providing directly-measured 3D velocity maps. Alternatively, vascular flow can be estimated from model-based computation fluid dynamics (CFD) calculations...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-015-0104-7
更新日期：2015-11-26 00:00:00
abstract：BACKGROUND:Sleep apnea (OSA) is a common sleep disorder characterized by recurring breathing pauses during sleep caused by a blockage of the upper airway (UA). The altered UA structure or function in OSA speakers has led to hypothesize the automatic analysis of speech for OSA assessment. In this paper we critically rev...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0138-5
更新日期：2016-02-20 00:00:00
abstract：BACKGROUND:The emergence of skin substitutes provides a new approach for the treatment of wound repair and healing. The consistent and steady release of angiogenic factors is an important factor in the promotion of angiogenesis in skin substitutes, which usually lack, yet need, a vascular network. METHODS:In this stud...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-134
更新日期：2013-12-31 00:00:00
abstract：BACKGROUND:Xenogeneic bone has been widely used in a variety of clinical bone-related disease to promote bone healing and restore bone defects. However, the adverse effects of immune system limit its application in the clinic. The aim of this study was to evaluate xenogeneic bone safety of immunotoxicity and explore th...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-019-0729-z
更新日期：2019-11-14 00:00:00
abstract：BACKGROUND:Endovascular intervention using a stent is a mainstream treatment for cerebral aneurysms. To assess the effect of intervention strategies on aneurysm hemodynamics, we have developed a fast virtual stenting (FVS) technique to simulate stent deployment in patient-specific aneurysms. However, quantitative valid...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0250-6
更新日期：2016-12-28 00:00:00
abstract：BACKGROUND:The subjects in EEG-Brain computer interface (BCI) system experience difficulties when attempting to obtain the consistent performance of the actual movement by motor imagery alone. It is necessary to find the optimal conditions and stimuli combinations that affect the performance factors of the EEG-BCI syst...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-91
更新日期：2011-10-12 00:00:00
abstract：BACKGROUND:Effective fixation of fracture requires careful selection of a suitable implant to provide stability and durability. Implant with a feature of locking plate (LP) has been used widely for treating distal fractures in femur because of its favourable clinical outcome, but its potential in fixing proximal fractu...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-11-23
更新日期：2012-04-30 00:00:00
abstract：:Since falls are a major public health problem among older people, the number of systems aimed at detecting them has increased dramatically over recent years. This work presents an extensive literature review of fall detection systems, including comparisons among various kinds of studies. It aims to serve as a referenc...
journal_title：Biomedical engineering online
pub_type： 杂志文章,评审
doi：10.1186/1475-925X-12-66
更新日期：2013-07-06 00:00:00
abstract：BACKGROUND:In order to characterize the intracranial pressure-volume reserve capacity, the correlation coefficient (R) between the ICP wave amplitude (A) and the mean ICP level (P), the RAP index, has been used to improve the diagnostic value of ICP monitoring. Baseline pressure errors (BPEs), caused by spontaneous shi...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-99
更新日期：2014-07-23 00:00:00
abstract：BACKGROUND:In cochlear implants (CI) measuring the electrically evoked compound action potential (ECAP) has become an important tool for verifying the electrode-nerve interface as well as establishing a basis for a map to program the speech processor. In a standard clinical setup recordings are averaged over 25-100 rep...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0588-z
更新日期：2018-10-19 00:00:00
abstract：BACKGROUND:Reach-grasp movements are motor components commonly affected after stroke and directly related to the independence of these individuals. Evaluations of these activities can be performed using clinical instruments and assessed by detailed and costly kinematic analyses. The aim of this study was to develop an ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-020-0758-7
更新日期：2020-03-04 00:00:00
abstract：BACKGROUND:Recent studies indicate that the blue-yellow colour discrimination is impaired in ADHD individuals. However, the relationship between colour and performance has not been investigated. This paper describes the development and the testing of a virtual environment that is capable to quantify the influence of re...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-74
更新日期：2011-08-19 00:00:00
abstract：BACKGROUND:With the aging population and rising healthcare costs, wearable monitoring is gaining importance. The motion artifact affecting dry electrodes is one of the main challenges preventing the widespread use of wearable monitoring systems. In this paper we investigate the motion artifact and ways of making a text...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-26
更新日期：2013-04-08 00:00:00
abstract：BACKGROUND:Intracranial pressure changes during head impact cause brain injuries such as vasogenic edema and cerebral contusion. However, the influence of impulsive pressure on endothelial function has not yet been fully studied in vitro. In this study, we developed a pressure loading device that produced positive and ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-44
更新日期：2014-04-16 00:00:00
abstract：BACKGROUND:Understanding aneurysm growth rate allows us to predict not only the current rupture risk, but also accumulated rupture risk in the future. However, determining growth rate of unruptured intracranial aneurysms often requires follow-up of patients for a long period of time so that significant growth can be ob...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-8-11
更新日期：2009-06-18 00:00:00
abstract：:The control of robotic prostheses based on pattern recognition algorithms is a widely studied subject that has shown promising results in acute experiments. The long-term implementation of this technology, however, has not yet been achieved due to practical issues that can be mainly attributed to the use of surface el...
journal_title：Biomedical engineering online
pub_type： 杂志文章,评审
doi：10.1186/1475-925X-11-33
更新日期：2012-06-20 00:00:00
abstract：BACKGROUND:STAR is a model-based, personalised, risk-based dosing approach for glycaemic control (GC) in critically ill patients. STAR provides safe, effective control to nearly all patients, using 1-3 hourly measurement and intervention intervals. However, the average 11-12 measurements per day required can be a clini...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-020-00771-6
更新日期：2020-04-29 00:00:00
abstract：BACKGROUND:Non-contact tonometers based on the method using air puff and Scheimpflug's fast camera are one of the latest devices allowing the measurement of intraocular pressure and additional biomechanical parameters of the cornea. Biomechanical features significantly affect changes in intraocular pressure values, as ...
journal_title：Biomedical engineering online
pub_type： 杂志文章,评审
doi：10.1186/s12938-019-0636-3
更新日期：2019-02-13 00:00:00
abstract：INTRODUCTION:This paper concerns the analysis of the features obtained from thyroid ultrasound images in left and right transverse and longitudinal sections. In the image analysis, the thyroid lobe is treated as a texture for healthy subjects and patients with Hashimoto's disease. The applied methods of analysis and im...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-11-48
更新日期：2012-08-16 00:00:00
abstract：BACKGROUND:Current devices for measuring muscle contraction in vivo have limited accuracy in establishing and re-establishing the optimum muscle length. They are variable in the reproducibility to determine the muscle contraction at this length, and often do not maintain precise conditions during the examination. Conse...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-6-1
更新日期：2007-01-02 00:00:00
abstract：BACKGROUND:Newborn mammals suffering from moderate hypoxia during or after birth are able to compensate a transitory lack of oxygen by adapting their vital functions. Exposure to hypoxia leads to an increase in the sympathetic tone causing cardio-respiratory response, peripheral vasoconstriction and vasodilatation in p...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-88
更新日期：2011-10-03 00:00:00
abstract：BACKGROUND:The challenges of glycaemic control in critically ill patients have been debated for 20 years. While glycaemic control shows benefits inter- and intra-patient metabolic variability results in increased hypoglycaemia and glycaemic variability, both increasing morbidity and mortality. Hence, current recommenda...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-019-0720-8
更新日期：2019-10-22 00:00:00
abstract：BACKGROUND:Red blood cells (RBCs) deform significantly and repeatedly when passing through narrow capillaries and delivering dioxygen throughout the body. Deformability of RBCs is a key characteristic, largely governed by the mechanical properties of the cell membrane. This study investigated RBC mechanical properties ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-017-0429-5
更新日期：2017-12-19 00:00:00
abstract：:A comment on G. Litscher: Infrared thermography fails to visualize stimulation-induced meridian-like structures. Biomed. Eng. OnLine 2005, 4:38 (15 June 2005), with a response by the author. ...
journal_title：Biomedical engineering online
pub_type： 评论,信件
doi：10.1186/1475-925X-10-80
更新日期：2011-09-11 00:00:00
