Abstract：
BACKGROUND:Nonnegative matrix factorization (NMF) has been successfully used for electroencephalography (EEG) spectral analysis. Since NMF was proposed in the 1990s, many adaptive algorithms have been developed. However, the performance of their use in EEG data analysis has not been fully compared. Here, we provide a comparison of four NMF algorithms in terms of accuracy of estimation, stability (repeatability of the results) and time complexity of algorithms with simulated data. In the practical application of NMF algorithms, stability plays an important role, which was an emphasis in the comparison. A Hierarchical clustering algorithm was implemented to evaluate the stability of NMF algorithms. RESULTS:In simulation-based comprehensive analysis of fit, stability, accuracy of estimation and time complexity, hierarchical alternating least squares (HALS) low-rank NMF algorithm (lraNMF_HALS) outperformed the other three NMF algorithms. In the application of lraNMF_HALS for real resting-state EEG data analysis, stable and interpretable features were extracted. CONCLUSION:Based on the results of assessment, our recommendation is to use lraNMF_HALS, providing the most accurate and robust estimation.
journal_name
Biomed Eng Onlinejournal_title
Biomedical engineering onlineauthors
Hu G,Zhou T,Luo S,Mahini R,Xu J,Chang Y,Cong Fdoi
10.1186/s12938-020-00796-xsubject
Has Abstractpub_date
2020-07-31 00:00:00pages
61issue
1issn
1475-925Xpii
10.1186/s12938-020-00796-xjournal_volume
19pub_type
杂志文章abstract：BACKGROUND:Segmentation is the most crucial part in the computer-aided bone age assessment. A well-known type of segmentation performed in the system is adaptive segmentation. While providing better result than global thresholding method, the adaptive segmentation produces a lot of unwanted noise that could affect the ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-87
更新日期：2011-09-28 00:00:00
abstract：BACKGROUND:Mechanobiological studies allow the characterization of cell response to mechanical stresses. Cells need to be supported by a material with properties similar to the physiological environment. Silicone elastomers have been used to produce various in vitro scaffolds of different geometries for endothelial cel...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-017-0380-5
更新日期：2017-07-14 00:00:00
abstract：BACKGROUND:Good anatomical compatibility is an important aspect in the development of cardiovascular implants. This work analyzes the interaction of the pump unit of an electrically driven pulsatile Total Artificial Heart (TAH) and the mediastinum. For an adequate compliance, both overall dimensions and alignment of in...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-81
更新日期：2013-08-14 00:00:00
abstract：BACKGROUND:With the aging population and rising healthcare costs, wearable monitoring is gaining importance. The motion artifact affecting dry electrodes is one of the main challenges preventing the widespread use of wearable monitoring systems. In this paper we investigate the motion artifact and ways of making a text...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-26
更新日期：2013-04-08 00:00:00
abstract：PURPOSE:Coronary artery bypass graft (CABG) surgery represents the standard treatment of advanced coronary artery disease. Two major types of anastomosis exist to connect the graft to the coronary artery, i.e., by using an end-to-side or a side-to-side anastomosis. There is still controversy because of the differences ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-6-35
更新日期：2007-09-26 00:00:00
abstract：BACKGROUND:Many studies have demonstrated that the geometry of the carotid bifurcation enables prediction of blood flow variation associated with atherosclerotic plaque formation. The phase angle between the arterial wall circumferential strain and its instantaneous wall shear stress is known as stress phase angle (SPA...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0458-8
更新日期：2018-03-02 00:00:00
abstract：BACKGROUND:Dendritic cells are potent and specialized antigen presenting cells, which play a crucial role in initiating and amplifying both the innate and adaptive immune responses. The dendritic cell-based vaccination against cancer has been clinically achieved promising successes. But there are still many challenges ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-2
更新日期：2014-01-10 00:00:00
abstract：BACKGROUND:Blood pressure (BP) is associated with early atherosclerosis and plaque rupture because the BP variability can significantly affect the blood flow velocity and shear stress over the plaque. However, the mechanical response of BP variability to the plaque remains unclear. Therefore, we investigated the correl...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-152
更新日期：2014-11-20 00:00:00
abstract：BACKGROUND:Computational modeling of cardiovascular flow is a growing and useful field, but such simulations usually require the researcher to guess the flow's inlet and outlet conditions since they are difficult and expensive to measure. It is critical to determine the amount of uncertainty introduced by these assumpt...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0497-1
更新日期：2018-05-30 00:00:00
abstract：BACKGROUND:Xenogeneic bone has been widely used in a variety of clinical bone-related disease to promote bone healing and restore bone defects. However, the adverse effects of immune system limit its application in the clinic. The aim of this study was to evaluate xenogeneic bone safety of immunotoxicity and explore th...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-019-0729-z
更新日期：2019-11-14 00:00:00
abstract：BACKGROUND:The biomechanical simulation of the human respiratory system is expected to be a useful tool for the diagnosis and treatment of respiratory diseases. Because the deformation of the thorax significantly influences airflow in the lungs, we focused on simulating the thorax deformation by introducing contraction...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0132-y
更新日期：2016-02-06 00:00:00
abstract：BACKGROUND:Gait analysis and research have been developed to obtain characteristics of movement patterns of people while walking. However, traditional measuring systems present different drawbacks that reduce their use and application. Among those drawbacks one can find: high price, low sampling frequency and limiting ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-34
更新日期：2014-03-31 00:00:00
abstract：BACKGROUND:Surface electromyographic (S-EMG) signal processing has been emerging in the past few years due to its non-invasive assessment of muscle function and structure and because of the fast growing rate of digital technology which brings about new solutions and applications. Factors such as sampling rate, quantiza...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-22
更新日期：2014-02-27 00:00:00
abstract：BACKGROUND:Approximately one-third of the human lifespan is spent sleeping. To diagnose sleep problems, all-night polysomnographic (PSG) recordings including electroencephalograms (EEGs), electrooculograms (EOGs) and electromyograms (EMGs), are usually acquired from the patient and scored by a well-trained expert accor...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-11-52
更新日期：2012-08-21 00:00:00
abstract：BACKGROUND:Tumor hypoxia is involved in every stage of solid tumor development: formation, progression, metastasis, and apoptosis. Two types of hypoxia exist in tumors-chronic hypoxia and acute hypoxia. Recent studies indicate that the regional hypoxia kinetics is closely linked to metastasis and therapeutic responses,...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0235-5
更新日期：2016-10-12 00:00:00
abstract：BACKGROUND:This paper proposes a methodology for helping bridge the gap between the complex waveform information frequently available in an intensive care unit and the simple, lumped values favoured for rapid clinical diagnosis and management. This methodology employs a simple waveform contour analysis approach to comp...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0603-4
更新日期：2018-11-20 00:00:00
abstract：BACKGROUND:Kinematics measures from inertial sensors have a value in the clinical assessment of pathological gait, to track quantitatively the outcome of interventions and rehabilitation programs. To become a standard tool for clinicians, it is necessary to evaluate their capability to provide reliable and comprehensib...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-146
更新日期：2014-10-21 00:00:00
abstract：:A comment on G. Litscher: Infrared thermography fails to visualize stimulation-induced meridian-like structures. Biomed. Eng. OnLine 2005, 4:38 (15 June 2005), with a response by the author. ...
journal_title：Biomedical engineering online
pub_type： 评论,信件
doi：10.1186/1475-925X-10-80
更新日期：2011-09-11 00:00:00
abstract：BACKGROUND:Human embryonic stem cell derived cardiomyocytes (hESC-CMs) hold high potential for basic and applied cardiovascular research. The development of a reliable simulation platform able to mimic the functional properties of hESC-CMs would be of considerable value to perform preliminary test complementing in vitr...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-11-61
更新日期：2012-08-28 00:00:00
abstract：BACKGROUND:The emergence of skin substitutes provides a new approach for the treatment of wound repair and healing. The consistent and steady release of angiogenic factors is an important factor in the promotion of angiogenesis in skin substitutes, which usually lack, yet need, a vascular network. METHODS:In this stud...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-134
更新日期：2013-12-31 00:00:00
abstract：BACKGROUND:This work deals with copyright protection of digital images, an issue that needs protection of intellectual property rights. It is an important issue with a large number of medical images interchanged on the Internet every day. So, it is a challenging task to ensure the integrity of received images as well a...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-015-0101-x
更新日期：2015-11-25 00:00:00
abstract：BACKGROUND:Frequency selectivity (FS) of the auditory system is established at the level of the cochlea and it is important for the perception of complex sounds. Although direct measurements of cochlear FS require surgical preparation, it can also be estimated with the measurements of otoacoustic emissions or behaviora...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0167-0
更新日期：2016-05-10 00:00:00
abstract：PURPOSE:We propose a collaborative and secure transmission scheme in order to safely and efficiently transmit medical data and provide telemedicine services, lighten the load on wireless access networks, and improve the quality of medical treatment such as surgery. METHODS:First, the transmission technology based on o...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-019-0674-x
更新日期：2019-05-20 00:00:00
abstract：BACKGROUND:Studies found that treatment symptoms of concern to oncology/hematology patients were greatly under-identified in medical records. On average, 11.0 symptoms were reported of concern to patients compared to 1.5 symptoms identified in their medical records. A solution to this problem is use of an electronic sy...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-14-S2-S1
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:The lumbar range of motion has traditionally been used to assess disability in patients with low back disorders. Controversy exists about how movement ranges in static positions or in a single straight plane is related to the functional status of the patients. The trunk circumduction, as the result of neurom...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-4
更新日期：2013-01-11 00:00:00
abstract：BACKGROUND:The pupillary light reflex characterizes the direct and consensual response of the eye to the perceived brightness of a stimulus. It has been used as indicator of both neurological and optic nerve pathologies. As with other eye reflexes, this reflex constitutes an almost instantaneous movement and is linked ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-015-0016-6
更新日期：2015-03-13 00:00:00
abstract：:It was highlighted that the original article [1] contained an error in the Acknowledgments section. ...
journal_title：Biomedical engineering online
pub_type： 杂志文章,已发布勘误
doi：10.1186/s12938-019-0707-5
更新日期：2019-08-08 00:00:00
abstract：BACKGROUND:This study investigates CAD/CAM ceramic cusp-replacing restoration resistance with and without buccal cusp replacement under static and dynamic cyclic loads, monitored using the acoustic emission (AE) technique. METHOD:The cavity was designed in a typical MODP (mesial-occlusal-distal-palatal) restoration fa...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-165
更新日期：2014-12-13 00:00:00
abstract：BACKGROUND:Exercise has been found to either reduce or increase arterial stiffness. Land-based exercise modalities have been documented as effective physical therapies to decrease arterial stiffness. However, these land-based exercise modalities may not be suitable for overweight individuals, in terms of risks of joint...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0274-y
更新日期：2016-12-28 00:00:00
abstract：BACKGROUND:Optical imaging is one of the most common, low-cost imaging tools used for investigating the tumor biological behavior in vivo. This study explores the feasibility and sensitivity of a near infrared fluorescent protein mKate2 for a long-term non-invasive tumor imaging in BALB/c nude mice, by using a low-powe...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0615-0
更新日期：2018-12-29 00:00:00
