Flow and wall shear stress in end-to-side and side-to-side anastomosis of venous coronary artery bypass grafts.

Abstract:

PURPOSE:Coronary artery bypass graft (CABG) surgery represents the standard treatment of advanced coronary artery disease. Two major types of anastomosis exist to connect the graft to the coronary artery, i.e., by using an end-to-side or a side-to-side anastomosis. There is still controversy because of the differences in the patency rates of the two types of anastomosis. The purpose of this paper is to non-invasively quantify hemodynamic parameters, such as mass flow and wall shear stress (WSS), in end-to-side and side-to-side anastomoses of patients with CABG using computational fluid dynamics (CFD). METHODS:One patient with saphenous CABG and end-to-side anastomosis and one patient with saphenous CABG and side-to-side anastomosis underwent 16-detector row computed tomography (CT). Geometric models of coronary arteries and bypasses were reconstructed for CFD analysis. Blood flow was considered pulsatile, laminar, incompressible and Newtonian. Peri-anastomotic mass flow and WSS were quantified and flow patterns visualized. RESULTS:CFD analysis based on in-vivo CT coronary angiography data was feasible in both patients. For both types of CABG, flow patterns were characterized by a retrograde flow into the native coronary artery. WSS variations were found in both anastomoses types, with highest WSS values at the heel and lowest WSS values at the floor of the end-to-side anastomosis. In contrast, the highest WSS values of the side-to-side anastomosis configuration were found in stenotic vessel segments and not in the close vicinity of the anastomosis. Flow stagnation zones were found in end-to-side but not in side-to-side anastomosis, the latter also demonstrating a smoother stream division throughout the cardiac cycle. CONCLUSION:CFD analysis of venous CABG based on in-vivo CT datasets in patients was feasible producing qualitative and quantitative information on mass flow and WSS. Differences were found between the two types of anastomosis warranting further systematic application of the presented methodology on multiple patient datasets.

journal_name

Biomed Eng Online

authors

Frauenfelder T,Boutsianis E,Schertler T,Husmann L,Leschka S,Poulikakos D,Marincek B,Alkadhi H

doi

10.1186/1475-925X-6-35

subject

Has Abstract

pub_date

2007-09-26 00:00:00

pages

35

issn

1475-925X

pii

1475-925X-6-35

journal_volume

6

pub_type

杂志文章
  • Blood pressure waveform contour analysis for assessing peripheral resistance changes in sepsis.

    abstract:BACKGROUND:This paper proposes a methodology for helping bridge the gap between the complex waveform information frequently available in an intensive care unit and the simple, lumped values favoured for rapid clinical diagnosis and management. This methodology employs a simple waveform contour analysis approach to comp...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0603-4

    authors: Davidson S,Pretty C,Balmer J,Desaive T,Chase JG

    更新日期:2018-11-20 00:00:00

  • Atomic force microscopy in vitro study of surface roughness and fractal character of a dental restoration composite after air-polishing.

    abstract:BACKGROUND:Surface roughness is the main factor determining bacterial adhesion, biofilm growth and plaque formation on the dental surfaces in vivo. Air-polishing of dental surfaces removes biofilm but can also damage the surface by increasing its roughness. The purpose of this study was to investigate the surface damag...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-9-59

    authors: Salerno M,Giacomelli L,Derchi G,Patra N,Diaspro A

    更新日期:2010-10-12 00:00:00

  • Collaborative and secure transmission of medical data applied to mobile healthcare.

    abstract:PURPOSE:We propose a collaborative and secure transmission scheme in order to safely and efficiently transmit medical data and provide telemedicine services, lighten the load on wireless access networks, and improve the quality of medical treatment such as surgery. METHODS:First, the transmission technology based on o...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-019-0674-x

    authors: Chen W,Chen Z,Cui F

    更新日期:2019-05-20 00:00:00

  • A development of assistant surgical robot system based on surgical-operation-by-wire and hands-on-throttle-and-stick.

    abstract:BACKGROUND:Robot-assisted laparoscopic surgery offers several advantages compared with open surgery and conventional minimally invasive surgery. However, one issue that needs to be resolved is a collision between the robot arm and the assistant instrument. This is mostly caused by miscommunication between the surgeon a...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0189-7

    authors: Kim M,Lee C,Park WJ,Suh YS,Yang HK,Kim HJ,Kim S

    更新日期:2016-05-20 00:00:00

  • Automated identification of reference genes based on RNA-seq data.

    abstract:BACKGROUND:Gene expression analyses demand appropriate reference genes (RGs) for normalization, in order to obtain reliable assessments. Ideally, RG expression levels should remain constant in all cells, tissues or experimental conditions under study. Housekeeping genes traditionally fulfilled this requirement, but the...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-017-0356-5

    authors: Carmona R,Arroyo M,Jiménez-Quesada MJ,Seoane P,Zafra A,Larrosa R,Alché JD,Claros MG

    更新日期:2017-08-18 00:00:00

  • Fine-grain recordings of the electrically evoked compound action potential amplitude growth function in cochlear implant recipients.

    abstract:BACKGROUND:In cochlear implants (CI) measuring the electrically evoked compound action potential (ECAP) has become an important tool for verifying the electrode-nerve interface as well as establishing a basis for a map to program the speech processor. In a standard clinical setup recordings are averaged over 25-100 rep...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0588-z

    authors: Gärtner L,Lenarz T,Büchner A

    更新日期:2018-10-19 00:00:00

  • The use of chilled condensers for the recovery of perfluorocarbon liquid in an experimental model of perfluorocarbon vapour loss during neonatal partial liquid ventilation.

    abstract:BACKGROUND:Perfluorocarbon (PFC) vapour in the expired gases during partial liquid ventilation should be prevented from entering the atmosphere and recovered for potential reuse. This study aimed to determine how much PFC liquid could be recovered using a conventional humidified neonatal ventilator with chilled condens...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-6-19

    authors: Dunster KR,Davies MW,Fraser JF

    更新日期:2007-05-31 00:00:00

  • Quantification of functional hand grip using electromyography and inertial sensor-derived accelerations: clinical implications.

    abstract:BACKGROUND:Assessing hand injury is of great interest given the level of involvement of the hand with the environment. Knowing different assessment systems and their limitations generates new perspectives. The integration of digital systems (accelerometry and electromyography) as a tool to supplement functional assessm...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-13-161

    authors: Martin-Martin J,Cuesta-Vargas AI

    更新日期:2014-12-11 00:00:00

  • Extraction of average neck flexion angle during swallowing in neutral and chin-tuck positions.

    abstract:BACKGROUND:A common but debated technique in the management of swallowing difficulties is the chin tuck swallow, where the neck is flexed forward prior to swallowing. Natural variations in chin tuck angles across individuals may contribute to the differential effectiveness of the technique. METHODOLOGY:To facilitate t...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-8-25

    authors: Hung D,Sejdić E,Steele CM,Chau T

    更新日期:2009-10-07 00:00:00

  • In-vivo coronary flow profiling based on biplane angiograms: influence of geometric simplifications on the three-dimensional reconstruction and wall shear stress calculation.

    abstract:BACKGROUND:Clinical studies suggest that local wall shear stress (WSS) patterns modulate the site and the progression of atherosclerotic lesions. Computational fluid dynamics (CFD) methods based on in-vivo three-dimensional vessel reconstructions have recently been shown to provide prognostically relevant WSS data. Thi...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-5-39

    authors: Wellnhofer E,Goubergrits L,Kertzscher U,Affeld K

    更新日期:2006-06-14 00:00:00

  • Safety assessment of near infrared light emitting diodes for diffuse optical measurements.

    abstract:BACKGROUND:Near infrared (NIR) light has been used widely to monitor important hemodynamic parameters in tissue non-invasively. Pulse oximetry, near infrared spectroscopy, and diffuse optical tomography are examples of such NIR light-based applications. These and other similar applications employ either lasers or light...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-3-9

    authors: Bozkurt A,Onaral B

    更新日期:2004-03-22 00:00:00

  • Identification of heart rate dynamics during moderate-to-vigorous treadmill exercise.

    abstract:BACKGROUND:Heart rate can be used to prescribe exercise intensity for development and maintenance of cardiorespiratory fitness. The aim of this study was to identify the dynamics of heart rate response during moderate-to-vigorous treadmill exercise and to explore parameter dependencies with respect to time, intensity l...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-015-0112-7

    authors: Hunt KJ,Fankhauser SE,Saengsuwan J

    更新日期:2015-12-21 00:00:00

  • Study on the biomechanical responses of the loaded bone in macroscale and mesoscale by multiscale poroelastic FE analysis.

    abstract:BACKGROUND:Bone is a hierarchically structured composite material, and different hierarchical levels exhibit diverse material properties and functions. The stress and strain distribution and fluid flow in bone play an important role in the realization of mechanotransduction and bone remodeling. METHODS:To investigate ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-019-0741-3

    authors: Yu W,Wu X,Cen H,Guo Y,Li C,Wang Y,Qin Y,Chen W

    更新日期:2019-12-23 00:00:00

  • An efficient framework for estimation of muscle fiber orientation using ultrasonography.

    abstract:BACKGROUND:Muscle fiber orientation (MFO) is an important parameter related to musculoskeletal functions. The traditional manual method for MFO estimation in sonograms was labor-intensive. The automatic methods proposed in recent years also involved voting procedures which were computationally expensive. METHODS:In th...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-12-98

    authors: Ling S,Chen B,Zhou Y,Yang WZ,Zhao YQ,Wang L,Zheng YP

    更新日期:2013-09-30 00:00:00

  • Heart rate analysis in normal subjects of various age groups.

    abstract:BACKGROUND:Analysis of heart rate variation (HRV) has become a popular noninvasive tool for assessing the activities of the autonomic nervous system (ANS). HRV analysis is based on the concept that fast fluctuations may specifically reflect changes of sympathetic and vagal activity. It shows that the structure generati...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-3-24

    authors: Acharya U R,Kannathal N,Sing OW,Ping LY,Chua T

    更新日期:2004-07-20 00:00:00

  • Short-term mechanical stretch fails to differentiate human adipose-derived stem cells into cardiovascular cell phenotypes.

    abstract:BACKGROUND:We and others have previously demonstrated that adipose-derived stem cells (ASCs) transplantation improve cardiac dysfunction post-myocardium infarction (MI) under hemodynamic stress in rats. The beneficial effects appear to be associated with pleiotropic factors due to a complex interplay between the transp...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-13-54

    authors: Girão-Silva T,Bassaneze V,Campos LC,Barauna VG,Dallan LA,Krieger JE,Miyakawa AA

    更新日期:2014-05-01 00:00:00

  • Automatic method of analysis and measurement of additional parameters of corneal deformation in the Corvis tonometer.

    abstract:INTRODUCTION:The method for measuring intraocular pressure using the Corvis tonometer provides a sequence of images of corneal deformation. Deformations of the cornea are recorded using the ultra-high-speed Scheimpflug camera. This paper presents a new and reproducible method of analysis of corneal deformation images t...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-13-150

    authors: Koprowski R

    更新日期:2014-11-19 00:00:00

  • Wound healing of human embryonic stem cell-derived retinal pigment epithelial cells is affected by maturation stage.

    abstract:BACKGROUND:Wound healing of retinal pigment epithelium (RPE) is a complex process that may take place in common age-related macular degeneration eye disease. The purpose of this study was to evaluate whether wounding and wound healing has an effect on Ca2+ dynamics in human embryonic stem cell (hESC)-RPEs cultured diff...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0535-z

    authors: Abu Khamidakh AE,Rodriguez-Martinez A,Kaarniranta K,Kallioniemi A,Skottman H,Hyttinen J,Juuti-Uusitalo K

    更新日期:2018-07-31 00:00:00

  • Comparison of named entity recognition methodologies in biomedical documents.

    abstract:BACKGROUND:Biomedical named entity recognition (Bio-NER) is a fundamental task in handling biomedical text terms, such as RNA, protein, cell type, cell line, and DNA. Bio-NER is one of the most elementary and core tasks in biomedical knowledge discovery from texts. The system described here is developed by using the Bi...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0573-6

    authors: Song HJ,Jo BC,Park CY,Kim JD,Kim YS

    更新日期:2018-11-06 00:00:00

  • The influence of probe level on the tuning of stimulus frequency otoacoustic emissions and behavioral test in human.

    abstract:BACKGROUND:Frequency selectivity (FS) of the auditory system is established at the level of the cochlea and it is important for the perception of complex sounds. Although direct measurements of cochlear FS require surgical preparation, it can also be estimated with the measurements of otoacoustic emissions or behaviora...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0167-0

    authors: Wang Y,Gong Q,Zhang T

    更新日期:2016-05-10 00:00:00

  • Computer-aided analysis of micro-morphological structure of porous membranes.

    abstract:BACKGROUND:The paper presents an approach and computer-aided method of numerical evaluation of the quality of porous membranes used as scaffolds for cultivation of chondrocytes in regeneration of biological tissues. MATERIALS:The scanning electron microscope (SEM) images of 300× and 1000× magnification presenting the ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0481-9

    authors: Kulikowski JL,Przytulska M,Chwojnowski A

    更新日期:2018-05-30 00:00:00

  • Temporal fluctuations of tremor signals from inertial sensor: a preliminary study in differentiating Parkinson's disease from essential tremor.

    abstract:BACKGROUND:Parkinson's disease (PD) and essential tremor (ET) are the two most common movement disorders but the rate of misdiagnosis rate in these disorders is high due to similar characteristics of tremor. The purpose of the study is to present: (a) a solution to identify PD and ET patients by using the novel measure...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-015-0098-1

    authors: Thanawattano C,Pongthornseri R,Anan C,Dumnin S,Bhidayasiri R

    更新日期:2015-11-04 00:00:00

  • Open source model for generating RR intervals in atrial fibrillation and beyond.

    abstract:BACKGROUND:Realistic modeling of cardiac inter-beat (RR) intervals is highly desirable for basic research in cardiac electrophysiology, clinical management of heart diseases, and developing signal processing tools for ECG analysis. METHODS:We present an open source computer model that is capable to generate realistic ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-6-9

    authors: Lian J,Clifford GD,Müssig D,Lang V

    更新日期:2007-03-02 00:00:00

  • Developing functional workspace for the movement of trunk circumduction in healthy young subjects: a reliability study.

    abstract:BACKGROUND:The lumbar range of motion has traditionally been used to assess disability in patients with low back disorders. Controversy exists about how movement ranges in static positions or in a single straight plane is related to the functional status of the patients. The trunk circumduction, as the result of neurom...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-12-4

    authors: Cheng SC,Hsu CH,Ting YT,Kuo LC,Lin RM,Su FC

    更新日期:2013-01-11 00:00:00

  • Public access defibrillation: suppression of 16.7 Hz interference generated by the power supply of the railway systems.

    abstract:BACKGROUND:A specific problem using the public access defibrillators (PADs) arises at the railway stations. Some countries as Germany, Austria, Switzerland, Norway and Sweden are using AC railroad net power-supply system with rated 16.7 Hz frequency modulated from 15.69 Hz to 17.36 Hz. The power supply frequency contam...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-4-16

    authors: Christov II,Iliev GL

    更新日期:2005-03-15 00:00:00

  • Real-time feature extraction of P300 component using adaptive nonlinear principal component analysis.

    abstract:BACKGROUND:The electroencephalography (EEG) signals are known to involve the firings of neurons in the brain. The P300 wave is a high potential caused by an event-related stimulus. The detection of P300s included in the measured EEG signals is widely investigated. The difficulties in detecting them are that they are mi...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-10-83

    authors: Turnip A,Hong KS,Jeong MY

    更新日期:2011-09-23 00:00:00

  • Using stochastic modelling to identify unusual continuous glucose monitor measurements and behaviour, in newborn infants.

    abstract:BACKGROUND:Abnormal blood glucose (BG) concentrations have been associated with increased morbidity and mortality in both critically ill adults and infants. Furthermore, hypoglycaemia and glycaemic variability have both been independently linked to mortality in these patients. Continuous Glucose Monitoring (CGM) device...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-11-45

    authors: Signal M,Le Compte A,Harris DL,Weston PJ,Harding JE,Chase JG,CHYLD Study Group.

    更新日期:2012-08-06 00:00:00

  • Reviewing the connection between speech and obstructive sleep apnea.

    abstract:BACKGROUND:Sleep apnea (OSA) is a common sleep disorder characterized by recurring breathing pauses during sleep caused by a blockage of the upper airway (UA). The altered UA structure or function in OSA speakers has led to hypothesize the automatic analysis of speech for OSA assessment. In this paper we critically rev...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0138-5

    authors: Espinoza-Cuadros F,Fernández-Pozo R,Toledano DT,Alcázar-Ramírez JD,López-Gonzalo E,Hernández-Gómez LA

    更新日期:2016-02-20 00:00:00

  • Effect of gamma radiation and accelerated aging on the mechanical and thermal behavior of HDPE/HA nano-composites for bone tissue regeneration.

    abstract:BACKGROUND:The replacement of hard tissues demands biocompatible and sometimes bioactive materials with properties similar to those of bone. Nano-composites made of biocompatible polymers and bioactive inorganic nano particles such as HDPE/HA have attracted attention as permanent bone substitutes due to their excellent...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-12-95

    authors: Alothman OY,Almajhdi FN,Fouad H

    更新日期:2013-09-24 00:00:00

  • Designing and testing scene enhancement algorithms for patients with retina degenerative disorders.

    abstract:BACKGROUND:Retina degenerative disorders represent the primary cause of blindness in UK and in the developed world. In particular, Age Related Macular Degeneration (AMD) and Retina Pigmentosa (RP) diseases are of interest to this study. We have therefore created new image processing algorithms for enhancing the visual ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-9-27

    authors: Al-Atabany WI,Memon MA,Downes SM,Degenaar PA

    更新日期:2010-06-18 00:00:00