Abstract:
BACKGROUND:Colonoscopy plays an important role in the clinical screening and management of colorectal cancer. The traditional 'see one, do one, teach one' training style for such invasive procedure is resource intensive and ineffective. Given that colonoscopy is difficult, and time-consuming to master, the use of virtual reality simulators to train gastroenterologists in colonoscopy operations offers a promising alternative. METHODS:In this paper, a realistic and real-time interactive simulator for training colonoscopy procedure is presented, which can even include polypectomy simulation. Our approach models the colonoscopy as thick flexible elastic rods with different resolutions which are dynamically adaptive to the curvature of the colon. More material characteristics of this deformable material are integrated into our discrete model to realistically simulate the behavior of the colonoscope. CONCLUSION:We present a simulator for training colonoscopy procedure. In addition, we propose a set of key aspects of our simulator that give fast, high fidelity feedback to trainees. We also conducted an initial validation of this colonoscopic simulator to determine its clinical utility and efficacy.
journal_name
Biomed Eng Onlinejournal_title
Biomedical engineering onlineauthors
Wen T,Medveczky D,Wu J,Wu Jdoi
10.1186/s12938-018-0433-4subject
Has Abstractpub_date
2018-01-25 00:00:00pages
9issue
1issn
1475-925Xpii
10.1186/s12938-018-0433-4journal_volume
17pub_type
杂志文章abstract:BACKGROUND:The replacement of hard tissues demands biocompatible and sometimes bioactive materials with properties similar to those of bone. Nano-composites made of biocompatible polymers and bioactive inorganic nano particles such as HDPE/HA have attracted attention as permanent bone substitutes due to their excellent...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-12-95
更新日期:2013-09-24 00:00:00
abstract:BACKGROUND:The lumbar range of motion has traditionally been used to assess disability in patients with low back disorders. Controversy exists about how movement ranges in static positions or in a single straight plane is related to the functional status of the patients. The trunk circumduction, as the result of neurom...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-12-4
更新日期:2013-01-11 00:00:00
abstract:BACKGROUND:Mitral valve failure can require repair or replacement. Replacement bioprosthetic valves are treated with glutaraldehyde prior to implantation. The aim of this study was to determine the changes in mechanical properties following glutaraldehyde fixation of mitral valve chordae. METHODS:To investigate the im...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0524-2
更新日期:2018-07-13 00:00:00
abstract:BACKGROUND:Tumor hypoxia is involved in every stage of solid tumor development: formation, progression, metastasis, and apoptosis. Two types of hypoxia exist in tumors-chronic hypoxia and acute hypoxia. Recent studies indicate that the regional hypoxia kinetics is closely linked to metastasis and therapeutic responses,...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0235-5
更新日期:2016-10-12 00:00:00
abstract:BACKGROUND:The emergence and development of robot assistant interventional vascular surgery technologies have benefited many patients with cardiovascular or cerebrovascular diseases. Due to the absence of effective training measures, these new advanced technologies have not been fully utilized and only few experienced ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-016-0148-3
更新日期:2016-04-06 00:00:00
abstract:BACKGROUND:Understanding aneurysm growth rate allows us to predict not only the current rupture risk, but also accumulated rupture risk in the future. However, determining growth rate of unruptured intracranial aneurysms often requires follow-up of patients for a long period of time so that significant growth can be ob...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-8-11
更新日期:2009-06-18 00:00:00
abstract:BACKGROUND:The gait movement is an essential process of the human activity and the result of collaborative interactions between the neurological, articular and musculoskeletal systems, working efficiently together. This explains why gait analysis is important and increasingly used nowadays for the diagnosis of many dif...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0097-2
更新日期:2015-10-29 00:00:00
abstract:BACKGROUND:Many studies have demonstrated that the geometry of the carotid bifurcation enables prediction of blood flow variation associated with atherosclerotic plaque formation. The phase angle between the arterial wall circumferential strain and its instantaneous wall shear stress is known as stress phase angle (SPA...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0458-8
更新日期:2018-03-02 00:00:00
abstract:BACKGROUND:Falls can cause trauma, disability and death among older people. Ambulatory accelerometer devices are currently capable of detecting falls in a controlled environment. However, research suggests that most current approaches can tend to have insufficient sensitivity and specificity in non-laboratory environme...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-11-9
更新日期:2012-02-16 00:00:00
abstract:BACKGROUND:The electroencephalography (EEG) signals are known to involve the firings of neurons in the brain. The P300 wave is a high potential caused by an event-related stimulus. The detection of P300s included in the measured EEG signals is widely investigated. The difficulties in detecting them are that they are mi...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-10-83
更新日期:2011-09-23 00:00:00
abstract:OBJECTIVE:To evaluate the in vivo and in vitro performance of a China-made dialysis machine (SWS-4000). METHODS:This was a multi-center prospective controlled study consisting of both long-term in vitro evaluations and cross-over in vivo tests in 132 patients. The China-made SWS-4000 dialysis machine was compared with...
journal_title:Biomedical engineering online
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1186/s12938-017-0387-y
更新日期:2017-08-02 00:00:00
abstract:BACKGROUND:This study investigates CAD/CAM ceramic cusp-replacing restoration resistance with and without buccal cusp replacement under static and dynamic cyclic loads, monitored using the acoustic emission (AE) technique. METHOD:The cavity was designed in a typical MODP (mesial-occlusal-distal-palatal) restoration fa...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-13-165
更新日期:2014-12-13 00:00:00
abstract::The Editors-in-Chief have retracted this article [1] because, after publication, concerns were raised regarding the study design and statistical analysis. Post-publication review has confirmed firstly that within-group changes were highlighted rather than between-group differences as appropriate for a randomized trial...
journal_title:Biomedical engineering online
pub_type: 杂志文章,撤回出版物
doi:10.1186/s12938-020-0749-8
更新日期:2020-01-24 00:00:00
abstract:BACKGROUND:Wound healing of retinal pigment epithelium (RPE) is a complex process that may take place in common age-related macular degeneration eye disease. The purpose of this study was to evaluate whether wounding and wound healing has an effect on Ca2+ dynamics in human embryonic stem cell (hESC)-RPEs cultured diff...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0535-z
更新日期:2018-07-31 00:00:00
abstract:BACKGROUND:Pre-operative imaging devices generate high-resolution images but intra-operative imaging devices generate low-resolution images. To use high-resolution pre-operative images during surgery, they must be deformed to reflect intra-operative geometry of brain. METHODS:We employ biomechanical models, guided by ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-9-51
更新日期:2010-09-15 00:00:00
abstract:BACKGROUND:Surface electromyographic (S-EMG) signal processing has been emerging in the past few years due to its non-invasive assessment of muscle function and structure and because of the fast growing rate of digital technology which brings about new solutions and applications. Factors such as sampling rate, quantiza...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-13-22
更新日期:2014-02-27 00:00:00
abstract:BACKGROUND:Segmentation is the most crucial part in the computer-aided bone age assessment. A well-known type of segmentation performed in the system is adaptive segmentation. While providing better result than global thresholding method, the adaptive segmentation produces a lot of unwanted noise that could affect the ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-10-87
更新日期:2011-09-28 00:00:00
abstract:BACKGROUND:For electroporation-based therapies, accurate modeling of the electric field distribution within the target tissue is important for predicting the treatment volume. In response to conventional, unipolar pulses, the electrical impedance of a tissue varies as a function of the local electric field, leading to ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-14-S3-S3
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Computer-assisted arrhythmia recognition is critical for the management of cardiac disorders. Various techniques have been utilized to classify arrhythmias. Generally, these techniques classify two or three arrhythmias or have significantly large processing times. A simpler autoregressive modeling (AR) techn...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925x-1-5
更新日期:2002-11-13 00:00:00
abstract:BACKGROUND:In the last years, several methods and devices have been proposed to record the human mandibular movements, since they provide quantitative parameters that support the diagnosis and treatment of temporomandibular disorders. The techniques currently employed suffer from a number of drawbacks including high pr...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-12-17
更新日期:2013-02-22 00:00:00
abstract:BACKGROUND:Current devices for measuring muscle contraction in vivo have limited accuracy in establishing and re-establishing the optimum muscle length. They are variable in the reproducibility to determine the muscle contraction at this length, and often do not maintain precise conditions during the examination. Conse...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-6-1
更新日期:2007-01-02 00:00:00
abstract:BACKGROUND:Fiber-based optical spectroscopy has been widely used for biomedical applications. However, the effect of probe-sample distance on the collection efficiency has not been well investigated. METHOD:In this paper, we presented a theoretical model to maximize the illumination and collection efficiency in design...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-10-95
更新日期:2011-11-02 00:00:00
abstract::A large number of incommensurable metrics are currently used to report the performance of brain-computer interfaces (BCI) used for augmentative and alterative communication (AAC). The lack of standard metrics precludes the comparison of different BCI-based AAC systems, hindering rapid growth and development of this te...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-12-43
更新日期:2013-05-16 00:00:00
abstract:BACKGROUND:Computational modeling of cardiovascular flow is a growing and useful field, but such simulations usually require the researcher to guess the flow's inlet and outlet conditions since they are difficult and expensive to measure. It is critical to determine the amount of uncertainty introduced by these assumpt...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0497-1
更新日期:2018-05-30 00:00:00
abstract:PURPOSE:Coronary artery bypass graft (CABG) surgery represents the standard treatment of advanced coronary artery disease. Two major types of anastomosis exist to connect the graft to the coronary artery, i.e., by using an end-to-side or a side-to-side anastomosis. There is still controversy because of the differences ...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-6-35
更新日期:2007-09-26 00:00:00
abstract:BACKGROUND:Perfluorocarbon (PFC) vapour in the expired gases during partial liquid ventilation should be prevented from entering the atmosphere and recovered for potential reuse. This study aimed to determine how much PFC liquid could be recovered using a conventional humidified neonatal ventilator with chilled condens...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925X-6-19
更新日期:2007-05-31 00:00:00
abstract:BACKGROUND:It is generally accepted that cartilage adaptation and degeneration are mechanically mediated. Investigating the swelling behaviour of cartilage is important because the stress and strain state of cartilage is associated with the swelling and deformation behaviour. It is well accepted that the swelling of so...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/1475-925x-1-8
更新日期:2002-12-19 00:00:00
abstract:PURPOSE:We propose a collaborative and secure transmission scheme in order to safely and efficiently transmit medical data and provide telemedicine services, lighten the load on wireless access networks, and improve the quality of medical treatment such as surgery. METHODS:First, the transmission technology based on o...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-019-0674-x
更新日期:2019-05-20 00:00:00
abstract:BACKGROUND:Heart rate can be used to prescribe exercise intensity for development and maintenance of cardiorespiratory fitness. The aim of this study was to identify the dynamics of heart rate response during moderate-to-vigorous treadmill exercise and to explore parameter dependencies with respect to time, intensity l...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-015-0112-7
更新日期:2015-12-21 00:00:00
abstract:BACKGROUND:Image segmentation is an essential and non trivial task in computer vision and medical image analysis. Computed tomography (CT) is one of the most accessible medical examination techniques to visualize the interior of a patient's body. Among different computer-aided diagnostic systems, the applications dedic...
journal_title:Biomedical engineering online
pub_type: 杂志文章
doi:10.1186/s12938-018-0456-x
更新日期:2018-02-27 00:00:00