解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Torsional abnormalities of the femur represent a significant risk factor for patellar instability or patellofemoral complaints. Although their clinical implication has been demonstrated, there is still a debate going on about different aspects. These include, especially, the various methods of measurements with a wide...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030474
更新日期:2021-01-27 00:00:00
abstract::Objective: To determine blood transfusion practices, risk factors, and outcomes associated with the use of blood products in the setting of the acute management of burn patients at the Victorian Adult Burn Service. Background: Patients with burn injuries have variable transfusion requirements, based on a multitude of ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030476
更新日期:2021-01-27 00:00:00
abstract::Coronary artery calcification (CAC) is a feature of coronary atherosclerosis and a well-known risk factor for cardiovascular disease (CVD). As the absence of CAC is associated with a lower incidence rate of CVD, measurement of a CAC score is helpful for risk stratification when the risk decision is uncertain. This was...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030457
更新日期:2021-01-25 00:00:00
abstract::Permanent hypoparathyroidism, a feared thyroidectomy complication, leads to significant patient morbidity, medical treatment, and monitoring. This study explores whether preoperative high-dose vitamin D loading decreases the incidence of permanent hypoparathyroidism. In a subgroup analysis, the study examines the pred...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030442
更新日期:2021-01-24 00:00:00
abstract::The relationship between serum uric acid (SUA) and hypertension has been a subject of increasing interest since the 1870 discovery by Frederick Akbar Mahomed. Several epidemiological studies have shown a strong association between high SUA levels and the presence or the development of hypertension. Genetic analyses ha...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10030448
更新日期:2021-01-24 00:00:00
abstract::(1) Introduction: Several surgical therapy options for the treatment of pathologies of the long biceps tendon (LHB) have been established. However, tenotomy, as well as established tenodesis techniques, has disadvantages, such as cosmetic deformities, functional impairments and residual shoulder pain. This study prese...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030432
更新日期:2021-01-23 00:00:00
abstract::Ovarian endometrioma are found in up to 40% of women with endometriosis and 50% of infertile women. The best surgical approach for endometrioma and its impact on pregnancy rates is still controversial. Therefore, we conducted a literature review on surgical management of ovarian endometrioma and its impact on pregnanc...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10030414
更新日期:2021-01-22 00:00:00
abstract:BACKGROUND:Thyroid hormone modulation of cardiovascular function has been associated with cardiovascular disease. Recent evidence suggests that free thyroxine (FT4) levels are associated with an increase in systemic arterial stiffness, but little is known about the effects of FT4 at the local level of the common caroti...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030420
更新日期:2021-01-22 00:00:00
abstract::Anemia is a common feature of liver and bowel diseases. Although the main causes of anemia in these conditions are represented by gastrointestinal bleeding and iron deficiency, autoimmune hemolytic anemia should be considered in the differential diagnosis. Due to the epidemiological association, autoimmune hemolytic a...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10030423
更新日期:2021-01-22 00:00:00
abstract::The aim of this study was to compare surgical and refractive outcomes between phacotrabeculectomy (P-Trab) and phaco with Ex-PRESS (P-Ex-PRESS) for glaucoma at a 6-month follow-up. This prospective randomized controlled trial included 81 eyes; 43 eyes (53%) and 38 eyes (47%) were assigned to the P-Ex-PRESS and P-Trab ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030424
更新日期:2021-01-22 00:00:00
abstract::Intervertebral disc pathology is a common disorder that can be caused by genetic, mechanical, and behavioral factors; however, it is possible to slow its progression. Although environmental and behavioral factors were previously considered to be the sole causes of intervertebral disc pathologies such as disc herniatio...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10030409
更新日期:2021-01-21 00:00:00
abstract::Focal Segmental Glomerulosclerosis (FSGS) recurrence after kidney transplantation (KTx) is relatively frequent and is associated with poor graft survival. The aim of this study was to investigate which management strategies were associated with better outcomes in our cohort of KTx recipients with primary FSGS. We retr...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030373
更新日期:2021-01-20 00:00:00
abstract::Exercise has health benefits and prevents a range of chronic diseases caused by physiological and biological changes in the whole body. Generally, the metabolic regulation of skeletal muscle through exercise is known to have a protective effect on the pathogenesis of metabolic syndrome, non-alcoholic fatty liver disea...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10030385
更新日期:2021-01-20 00:00:00
abstract::Limited information on the effect of antiretroviral treatment (ART) on vascular function in South Africans of African descent living with human immunodeficiency virus (HIV) is available. The relationship between ART, vascular function and cardiovascular risk factors in South Africans of African ancestry with HIV was t...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030392
更新日期:2021-01-20 00:00:00
abstract::Inflammatory bowel diseases (IBDs) may be associated with extra-intestinal manifestations. Among these, mucocutaneous manifestations are relatively frequent, often difficult to diagnose and treat, and may complicate the course of the underlying disease. In the present review, a summary of the most relevant literature ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10020364
更新日期:2021-01-19 00:00:00
abstract:BACKGROUND:Prevalence estimates for sarcopenia vary depending on the ascertainment criteria and thresholds applied. We aimed to estimate the prevalence of sarcopenia using two international definitions but employing Australian population-specific cut-points. METHODS:Participants (n = 665; 323 women) aged 60-96 years o...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020343
更新日期:2021-01-18 00:00:00
abstract::This study aimed to investigate the cross-sectional association between arthritis and migraine in a large representative sample of the US adult population. The study used data from adults who participated in the RAND American Life Panel (ALP). Arthritis (excluding rheumatoid arthritis) and migraine were self-reported....
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020342
更新日期:2021-01-18 00:00:00
abstract::(1) Background: Focal chondral defects of the knee can significantly impair patient quality of life. Although different options are available, they are still not conclusive and have several limitations. The aim of this study was to evaluate the role of autologous cartilage micrografts in the treatment of knee chondrop...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020322
更新日期:2021-01-17 00:00:00
abstract::The reliable prediction of cochlear implant (CI) speech perception outcomes is highly relevant and can facilitate the monitoring of postoperative hearing performance. To date, multiple audiometric, demographic, and surgical variables have shown some degree of correlation with CI speech perception outcomes. In the pres...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020324
更新日期:2021-01-17 00:00:00
abstract::The incidence of acute and chronic pancreatitis is increasing in the United States. Rates of acute pancreatitis (AP) are similar in both sexes, but chronic pancreatitis (CP) is more common in males. When stratified by etiology, women have higher rates of gallstone AP, while men have higher rates of alcohol- and tobacc...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10020300
更新日期:2021-01-15 00:00:00
abstract::Two doses of propiverine ER (30 and 45 mg/d) are available for the treatment of overactive bladder (OAB) syndrome. We have explored factors associated with the initial dosing choice (allocation bias), the decision to adapt dosing (escalation bias) and how dosing relative to other factors affects treatment outcomes. Da...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020311
更新日期:2021-01-15 00:00:00
abstract::The aim of the study was to examine the usefulness of targeted musculoskeletal ultrasonography (MSUS) in assessing the disease activity of patients with early inflammatory arthritis (EIA). Twenty-eight patients with EIA were enrolled. The MSUS examination of joints with arthritic signs (tenderness or swelling), measur...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020283
更新日期:2021-01-14 00:00:00
abstract::The identification of biomarkers predicting disease severity and outcomes is the focus of intense research in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 infection). Ideally, such biomarkers should be easily derivable from routine tests. We conducted a systematic review and meta-analysis ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020286
更新日期:2021-01-14 00:00:00
abstract::Arterial stiffness has been shown to be a subclinical marker associated with cardiovascular disease. Meanwhile, long-term exercise has been demonstrated to reduce arterial stiffness, providing a decrease in cardiovascular risk. However, the acute effect of exercise on arterial stiffness is unclear. This systematic rev...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10020291
更新日期:2021-01-14 00:00:00
abstract::Improving transgender people's quality of life (QoL) is the most important goal of gender-affirming care. Prospective changes in affect can influence QoL. We aim to assess the impact of initiating gender-affirming hormonal treatment (HT) on affect. In the European Network for the Investigation of Gender Incongruence (...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020296
更新日期:2021-01-14 00:00:00
abstract:PURPOSE:The risk of epiphora after medial maxillectomy with lacrimal duct transection is difficult to assess. The data available in the literature are inconclusive due to various operating techniques used by the authors of medical publications, different additional procedures aimed at improving tear drainage after maxi...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020245
更新日期:2021-01-12 00:00:00
abstract:OBJECTIVE:Clinical presentation of patients with mitral paravalvular leakage (PVL) varies from asymptomatic to heart failure related with hemolytic anemia or pulmonary hypertension. We aimed to investigate the structural and functional characteristics of mitral PVL by multimodal imaging and their association with the s...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020222
更新日期:2021-01-10 00:00:00
abstract::Background: We decided to investigate whether aneurysm wall enhancement (AWE) on high-resolution vessel wall magnetic resonance imaging (HR VW-MRI) coexists with the conventional risk factors for aneurysm rupture. Methods: We performed HR VW-MRI in 46 patients with 64 unruptured small intracranial aneurysms. Patient d...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020225
更新日期:2021-01-10 00:00:00
abstract::There are no reliable, non-invasive methods to accurately measure cardiac output (CO) in septic patients. MostCare (Vytech Health™, Vygon, Padova, Italy), is a beat-to-beat, self calibrated method for CO measurement based on continuous analysis of reflected arterial pressure waveforms. We enrolled 40 patients that wer...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020213
更新日期:2021-01-09 00:00:00
abstract:BACKGROUND:Congenital factor (F) VII deficiency is a rare coagulation factor deficiency with an estimated incidence of 1 per 500,000 individuals. Patients with severe FVII deficiency present a broad range of clinical presentations. Alloimmunization against exogenous FVII, as the main challenge of replacement therapy, i...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10020211
更新日期:2021-01-08 00:00:00
abstract::(1) Background: Endoscopic management of hilar biliary obstruction is still challenging. Compared with unilateral drainage, bilateral drainage could preserve larger functional liver volume and potentially improve clinical outcomes. To evaluate the effectiveness of bilateral drainage, we conducted this multicenter rand...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020206
更新日期:2021-01-08 00:00:00
abstract::Electrical enabling motor control (eEmc) through transcutaneous spinal cord stimulation is a non-invasive method that can modify the functional state of the sensory-motor system. We hypothesize that eEmc delivery, together with hand training, improves hand function in healthy subjects more than either intervention alo...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020195
更新日期:2021-01-07 00:00:00
abstract::The number of healthy and frail older adults is increasing worldwide, especially in industrialized countries, as a result of the increase in life expectancy [...]. ...
journal_title:Journal of clinical medicine
pub_type: 社论
doi:10.3390/jcm10020166
更新日期:2021-01-06 00:00:00
abstract::With the improvement in survival rate, cardiotoxicity has emerged as a significant adverse effect of cancer therapy. Early diagnosis of subclinical cardiac injury may allow the initiation of cardioprotective therapy and preventing the interruption of optimal cancer therapy and the development of irreversible cardiac d...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10010154
更新日期:2021-01-05 00:00:00
abstract::Tuberculosis (TB) remains a major health issue worldwide. In order to contain TB infections, improved vaccines as well as accurate and reliable diagnostic tools are desirable. Exosomes are employed for the diagnosis of various diseases. At present, research on exosomes in TB is still at the preliminary stage. Recent s...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10010145
更新日期:2021-01-04 00:00:00
abstract::Substantial progress in recent years has dramatically increased our knowledge of the molecular basis of cancer, revealing new potential therapeutic targets and paving the way for effective personalised medicine for the treatment of many tumour types. However, pancreatic cancer has been lagging behind in this success a...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10010149
更新日期:2021-01-04 00:00:00
abstract::The prognosis of multiple myeloma (MM) has improved with the introduction of novel agents. These data are largely derived from clinical trials and might not reflect real-world patient outcomes accurately. We surveyed real-world data from 284 patients newly diagnosed with MM between 2010 and 2018 in Miyazaki Prefecture...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10010105
更新日期:2020-12-30 00:00:00
abstract:AIM:Our aim was to investigate the characteristics, treatment and prognosis of patients with myocardial infarction (MI) treated outside a cardiology department (CD), compared with MI patients treated at a CD. METHODS:A cohort of 1310 patients diagnosed with MI at eight Swedish hospitals in 2011 were included in this o...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10010106
更新日期:2020-12-30 00:00:00
abstract::We aimed to explore the differences in the whole transcriptome of peripheral blood mononuclear cells between elderly individuals with and without type 2 diabetes (T2D). We conducted a microarray-based transcriptome analysis of 19 individuals with T2D and 15 without. Differentially expressed genes according to linear m...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10010085
更新日期:2020-12-29 00:00:00
abstract::Surgery, including minimally invasive surgery, and radiotherapy are key modalities in the treatment of gynecological malignancies. The aim of this review is to offer the multidisciplinary care team a comprehensive summary of the intersections of surgery and radiotherapy in the local treatment of gynecological malignan...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm10010093
更新日期:2020-12-29 00:00:00