Abstract：
AIM:Our aim was to investigate the characteristics, treatment and prognosis of patients with myocardial infarction (MI) treated outside a cardiology department (CD), compared with MI patients treated at a CD. METHODS:A cohort of 1310 patients diagnosed with MI at eight Swedish hospitals in 2011 were included in this observational study. Patients were followed regarding all-cause mortality until 2018. RESULTS:A total of 235 patients, exclusively treated outside CDs, were identified. These patients had more non-cardiac comorbidities, were older (mean age 83.7 vs. 73.1 years) and had less often type 1 MIs (33.2% vs. 74.2%), in comparison with the CD patients. Advanced age and an absence of chest pain were the strongest predictors of non-CD care. Only 3.8% of non-CD patients were investigated with coronary angiography and they were also prescribed secondary preventive pharmacological treatments to a lesser degree, with only 32.3% having statin therapy at discharge. The all-cause mortality was higher in non-CD patients, also after adjustment for baseline parameters, both at 30 days (hazard ratio (HR) 2.28; 95% confidence interval (CI) 1.62-3.22), one year (HR 1.82; 95% CI 1.39-2.36) and five years (HR 1.62; 95% CI 1.32-1.98). CONCLUSIONS:MI treatment outside CDs is associated with an adverse short- and long-term prognosis. An improved use of percutaneous coronary intervention (PCI) and secondary preventive pharmacological treatment might improve the long-term prognosis in these patients.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Gard A,Lindahl B,Hadziosmanovic N,Baron Tdoi
10.3390/jcm10010106subject
Has Abstractpub_date
2020-12-30 00:00:00issue
1issn
2077-0383pii
jcm10010106journal_volume
10pub_type
杂志文章abstract：BACKGROUND:The management of Helicobacter pylori (H. pylori) infection raises important challenges, still being the most common chronic infection worldwide in all age groups. In high-prevalence regions, paediatric patients need a specific focus, as the acquisition of the infection takes place in childhood. The objectiv...
journal_title：Journal of clinical medicine
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更新日期：2020-03-13 00:00:00
abstract：:Acute kidney injury and renal failure are common after heart transplantation. We retrospectively reviewed a national cohort and identified 1129 heart transplant patients. Patients receiving renal replacement therapy after heart transplantation were grouped into the dialysis cohort. The long-term survival and risk fact...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
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更新日期：2020-07-31 00:00:00
abstract：:Ocular surgery is one of the most performed medical procedures in the world. Its limitation or suspension, recursively extended over time, could be associated with a significant increase in the number of blind people worldwide. Indeed, cataract causes more than half of all cases of visual impairment in those countries...
journal_title：Journal of clinical medicine
pub_type： 社论
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更新日期：2020-05-09 00:00:00
abstract：:Pain in Sickle Cell Disease (SCD) is a major comorbidity and unique with acute pain due to recurrent and episodic vaso-occlusive crises as well as chronic pain, which can span an individual's entire life. Opioids are the mainstay treatment for pain in SCD. Due to recent health crises raised by adverse effects includin...
journal_title：Journal of clinical medicine
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更新日期：2020-12-01 00:00:00
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更新日期：2019-11-02 00:00:00
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更新日期：2020-01-07 00:00:00
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更新日期：2020-03-16 00:00:00
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pub_type： 杂志文章
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更新日期：2020-07-31 00:00:00
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更新日期：2018-11-21 00:00:00
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更新日期：2021-01-20 00:00:00
abstract：:The endogenous PP2A inhibitor SET Nuclear Proto-Oncogene (SET) has been reported to play oncogenic roles and determines poor outcomes in colorectal cancer (CRC). Our group previously showed that miR-199b is deregulated in metastatic CRC, and reduced the cell viability and enhanced the sensitivity of CRC cells to stand...
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pub_type： 杂志文章
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更新日期：2020-07-28 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章
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更新日期：2018-08-28 00:00:00
abstract：BACKGROUND AND AIMS:Endoscopic resection (ER) for submucosal invasive colorectal cancer (T1 CRC) can be grouped as curative ER (C-ER) and non-curative ER (NC-ER). Little is known about the long-term outcomes of patients in these two groups. Therefore, we have evaluated the long-term outcomes in endoscopically resected ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
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更新日期：2020-07-31 00:00:00
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pub_type： 杂志文章
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更新日期：2020-06-10 00:00:00
abstract：OBJECTIVE:To investigate the risk and risk factors for suicide attempt by patients with regular migraines (RM) and status migrainosus (SM) in Taiwan. METHODS:We analyzed a subset of the National Health Insurance Research Database of Taiwan and enrolled patients (≥20 years old) who had ever received a diagnosis of RM o...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm7090269
更新日期：2018-09-11 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
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更新日期：2020-10-21 00:00:00
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pub_type： 杂志文章
doi：10.3390/jcm9082448
更新日期：2020-07-31 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章
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更新日期：2019-03-21 00:00:00
abstract：:Despite extensive research and development of new treatments, acute myeloid leukemia (AML)-backbone therapy has remained essentially unchanged over the last decades and is frequently associated with poor outcomes. Eradicating the leukemic stem cells (LSCs) is the ultimate challenge in the treatment of AML. Emerging ev...
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pub_type： 杂志文章,评审
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更新日期：2020-05-18 00:00:00
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pub_type： 杂志文章,评审
doi：10.3390/jcm7060153
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pub_type： 杂志文章
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更新日期：2019-06-11 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2020-03-11 00:00:00
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journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm10010072
更新日期：2020-12-28 00:00:00
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更新日期：2017-01-06 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2020-04-28 00:00:00
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更新日期：2019-05-14 00:00:00
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更新日期：2020-02-02 00:00:00
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更新日期：2015-09-07 00:00:00
abstract：:Androgen/androgen receptor (AR) signaling is a significant driver of prostate cancer progression, therefore androgen-deprivation therapy (ADT) is often used as a standard form of treatment for advanced and metastatic prostate cancer patients. However, after several years of ADT, prostate cancer progresses to castratio...
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更新日期：2019-03-13 00:00:00
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更新日期：2018-04-10 00:00:00
