Abstract：
:Diabetic nephropathy patients traditionally show significant macroalbuminuria prior to the development of renal impairment. However, this clinical paradigm has recently been questioned. Epidemiological surveys confirm that chronic kidney disease (CKD) diagnosed by a low glomerular filtration rate (GFR) is more common in diabetic patients than in the non-diabetic population but a low number of patients had levels of proteinuria above that which traditionally defines overt diabetic nephropathy (>500 mg/g). The large number of patients with low levels of proteinuria suggests that the traditional clinical paradigm of overt diabetic nephropathy is changing since it does not seem to be the underlying renal lesion in most of diabetic subjects with CKD.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Robles NR,Villa J,Gallego RHdoi
10.3390/jcm4091761subject
Has Abstractpub_date
2015-09-07 00:00:00pages
1761-73issue
9issn
2077-0383pii
jcm4091761journal_volume
4pub_type
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