Abstract：
:Torsional abnormalities of the femur represent a significant risk factor for patellar instability or patellofemoral complaints. Although their clinical implication has been demonstrated, there is still a debate going on about different aspects. These include, especially, the various methods of measurements with a wide range of physiologic values, the indication or clear recommendation for surgical correction, and the site of the rotational osteotomy. Nevertheless, good subjective and objective functional results were reported after femoral rotational osteotomies. This is mostly not a review of the literature, but a collection of personal thoughts and observations.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Biedert RMdoi
10.3390/jcm10030474subject
Has Abstractpub_date
2021-01-27 00:00:00issue
3issn
2077-0383pii
jcm10030474journal_volume
10pub_type
杂志文章abstract：:Periprosthetic joint infection in total knee arthroplasty is a significant complication that is a common reason for revision surgery. The current standard of care is two-stage revision surgery. There is however increasing evidence to support the use of single-stage revision surgery. We conducted a PRISMA systematic re...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm8020174
更新日期：2019-02-02 00:00:00
abstract：BACKGROUND:Patients with diabetic kidney disease (DKD) are at higher risk of hypoglycemia than diabetic patients without DKD. We aimed to investigate the temporal trends of severe hypoglycemia in advanced DKD patients transitioning to dialysis and examine risk factors associated with severe hypoglycemia. We also invest...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8040420
更新日期：2019-03-27 00:00:00
abstract：:Background: We performed this prospective double-blind randomized controlled trial to identify the effect of a preoperative prophylactic transdermal scopolamine (TDS) patch on postoperative nausea and vomiting (PONV) after retromastoid craniectomy with microvascular decompression (RMC-MVD). Methods: We recruited 38 pa...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9010156
更新日期：2020-01-07 00:00:00
abstract：:The incidence of acute and chronic pancreatitis is increasing in the United States. Rates of acute pancreatitis (AP) are similar in both sexes, but chronic pancreatitis (CP) is more common in males. When stratified by etiology, women have higher rates of gallstone AP, while men have higher rates of alcohol- and tobacc...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm10020300
更新日期：2021-01-15 00:00:00
abstract：:Thyroid hormones (THs) exert pleiotropic effects in different mammalian organs, including gonads. Genetic and non-genetic factors, such as ageing and environmental stressors (e.g., low-iodine intake, exposure to endocrine disruptors, etc.), can alter T4/T3 synthesis by the thyroid. In any case, peripheral T3, controll...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9061679
更新日期：2020-06-01 00:00:00
abstract：:Considering the progress made in the management of sickle cell disease during the past 30 years, along with the excellent results obtained with hematopoietic stem cell transplantation (SCT), it is important to reexamine why, who, when and how to recommend allogeneic SCT in children with sickle cell disease. While sick...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm8101523
更新日期：2019-09-22 00:00:00
abstract：:Substantial progress in recent years has dramatically increased our knowledge of the molecular basis of cancer, revealing new potential therapeutic targets and paving the way for effective personalised medicine for the treatment of many tumour types. However, pancreatic cancer has been lagging behind in this success a...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm10010149
更新日期：2021-01-04 00:00:00
abstract：:The ongoing coronavirus disease 2019 (COVID-19) pandemic has resulted in efforts to identify therapies to ameliorate adverse clinical outcomes. The recognition of the key role for increased inflammation in COVID-19 has led to a proliferation of clinical trials targeting inflammation. The purpose of this review is to c...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9092935
更新日期：2020-09-11 00:00:00
abstract：:Hereditary hemorrhagic telangiectasia (HHT) is characterized by mucocutaneous telangiectases and visceral vascular malformations. Individuals suffering from HHT have a significantly increased risk of bacterial infections, but the mechanisms involved in this are not clear. White blood cell subpopulations were estimated...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9030767
更新日期：2020-03-12 00:00:00
abstract：:Metabolic Syndrome (MetS) contributes to the development of cardiovascular disease (CVD) and type II diabetes mellitus (T2DM). Few studies have investigated the MetS risk of young adults (18⁻24 years old). This study aims to determine the prevalence of MetS in Appalachian and non-Appalachian students attending West Vi...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm7120487
更新日期：2018-11-27 00:00:00
abstract：BACKGROUND:Prostate cancer (PCa) is characterized by significant heterogeneity in its molecular, genomic, and immunologic characteristics. METHODS:Whole transcriptome RNAseq data from The Cancer Genome Atlas of prostate adenocarcinomas (n = 492) was utilized. The immune microenvironment was characterized using the CIB...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9061973
更新日期：2020-06-24 00:00:00
abstract：:We prospectively evaluated the relationship between meibomian gland dysfunction (MGD) and Graves' ophthalmopathy (GO) in 19 patients (38 eyes) with subjective dry eye symptoms, compared to 14 age-matched normal participants (14 eyes). Extraocular muscle and lacrimal gland enlargement were evaluated by magnetic resonan...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9092814
更新日期：2020-08-31 00:00:00
abstract：:Mitochondrial respiratory chain (MRC) disorders have a multifaceted clinical presentation and genetic origin[...]. ...
journal_title：Journal of clinical medicine
pub_type： 社论
doi：10.3390/jcm7040066
更新日期：2018-03-29 00:00:00
abstract：:Sodium glucose co-transporter 2 (SGLT2) inhibitors reduce the risk of heart and kidney failure in patients with type 2 diabetes, possibly due to diuretic effects. Previous non-placebo-controlled studies with SGLT2 inhibitors observed changes in volume markers in healthy individuals and in patients with type 2 diabetes...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8060779
更新日期：2019-05-31 00:00:00
abstract：:Clinical trials in attention-deficit/hyperactivity disorder (ADHD) have typically measured outcome using clinician ratings on the Attention-Deficit/Hyperactivity Disorder Rating Scale, Fourth Edition (ADHD-RS-IV) and the Clinical Global Impression-Improvement (CGI-I) scale. Remission has been defined as an endpoint sc...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8040461
更新日期：2019-04-05 00:00:00
abstract：:α-Klotho is a known anti-aging protein that exerts diverse physiological effects, including phosphate homeostasis. Klotho expression occurs predominantly in the kidney and is significantly decreased in patients with chronic kidney disease. However, changes in serum klotho levels and impacts of klotho on outcomes among...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9061834
更新日期：2020-06-12 00:00:00
abstract：:Topical application of vascular endothelial growth factor A (VEGFA) inhibitors including Bevacizumab is used for antiangiogenic therapy at the ocular surface. While clinical studies have suggested that this approach is well-tolerated, the effect of the drug on limbal epithelial stem cells has not been studied. In this...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8111925
更新日期：2019-11-09 00:00:00
abstract：:Joint bleeding represents the most commonly reported type of hemorrhage in patients affected by hemophilia. Although the widespread use of prophylaxis has been able to significantly reduce the onset of arthropathy, it has been shown that a non-negligible percentage of patients develop degenerative changes in their joi...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm6080077
更新日期：2017-07-31 00:00:00
abstract：:Adipokines are powerful agents involved in the development of obesity-dependent cancers. This prospective study aimed to investigate the association between pre-treatment body mass index (BMI) and serum YKL-40, leptin, and adiponectin concentrations as well as the plasma activity of tissue factor (TF) and the future p...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9061742
更新日期：2020-06-04 00:00:00
abstract：:Social media enables the public sharing of information. With the recent emphasis on transparency and the open sharing of information between doctors and patients, the intersection of social media and healthcare is of particular interest. Twitter is currently the most popular form of social media used for healthcare co...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm7060121
更新日期：2018-05-28 00:00:00
abstract：:Sleep bruxism (SB) is a masticatory muscle activity during sleep that is characterized as rhythmic (phasic) or non-rhythmic (tonic). The recent hypothesis on the etiology of SB supports the role of the central and autonomic nervous systems. Therefore, in this study, we aimed to assess the intensity of SB in patients w...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm7100327
更新日期：2018-10-05 00:00:00
abstract：:In the grey zone of testosterone levels between 8 and 12 nmol/L, the usefulness of therapy is controversial; as such, markers of tissue action of androgens may be helpful in adjusting clinical decisions. To better understand the effect of the hypothalamic-pituitary-testicular axis on male accessory secretion, we perfo...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8122128
更新日期：2019-12-03 00:00:00
abstract：BACKGROUND:Asthma patterns are not well established in epidemiological studies. AIM:To assess asthma patterns and risk factors in an adult general population sample. METHODS:In total, 452 individuals reporting asthma symptoms/diagnosis in previous surveys participated in the AGAVE survey (2011-2014). Latent transitio...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9113632
更新日期：2020-11-11 00:00:00
abstract：BACKGROUND:There is a lack of evidence regarding the link between apolipoproteins and cancer mortality. By using two nationally representative samples of US adults, we prospectively evaluated the associations between apolipoprotein B (apoB) levels and apoB/apoA-I ratio with cancer mortality. We also examined the role o...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9010170
更新日期：2020-01-08 00:00:00
abstract：INTRODUCTION:Dementia is a group of disorders that causes dysfunctions in human cognitive and operating functions. Currently, it is not possible to conduct a fast, low-invasive dementia diagnostic process with the use of peripheral blood biomarkers, however, there is a great deal of research in progress covering this s...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9113452
更新日期：2020-10-27 00:00:00
abstract：:There is increasing data in favour of follicle-stimulating hormone (FSH) therapy in patients with oligo-asthenozoospermia and normal-range gonadotropins in order to increase sperm count and above all sperm motility. Some studies showed an improvement in DNA fragmentation and spontaneous pregnancy. Recently, biosimilar...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9051478
更新日期：2020-05-14 00:00:00
abstract：:Customized cross-linking has been proposed as an alternative to conventional cross-linking in patients with progressive keratoconus, targeting greater flattening of the cone region and improved visual function. Epithelium-on cross-linking aims to reduce complications associated with epithelial removal, while the addit...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9103222
更新日期：2020-10-08 00:00:00
abstract：:Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of several solid and hematological malignancies. ICIs are not only able to produce long and durable responses, but also very well tolerated by patients. There are several approved indications of use of ICIs in treatment of metastatic gastrointestina...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9082533
更新日期：2020-08-06 00:00:00
abstract：:(1) Background: Focal chondral defects of the knee can significantly impair patient quality of life. Although different options are available, they are still not conclusive and have several limitations. The aim of this study was to evaluate the role of autologous cartilage micrografts in the treatment of knee chondrop...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm10020322
更新日期：2021-01-17 00:00:00
abstract：BACKGROUND:Current therapeutic options in the course of metastatic castration-resistant prostate cancers (mCRPC) reinforce the need for reliable tools to characterize the tumor in a dynamic way. Circulating tumor cells (CTCs) have emerged as a viable solution to the problem, whereby patients with a variety of solid tum...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9072066
更新日期：2020-07-01 00:00:00
