Abstract：
:The number of healthy and frail older adults is increasing worldwide, especially in industrialized countries, as a result of the increase in life expectancy [...].
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Manckoundia P,Putot Adoi
10.3390/jcm10020166subject
Has Abstractpub_date
2021-01-06 00:00:00issue
2issn
2077-0383pii
jcm10020166journal_volume
10pub_type
社论abstract：:The new allocation criteria classify patients on veno-arterial extracorporeal membranous oxygenation (VA-ECMO) as the highest priority for receiving orthotopic heart transplantation (OHT) especially if they are considered not candidates for ventricular assist devices. The outcomes of patients who receive ventricular a...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8050572
更新日期：2019-04-26 00:00:00
abstract：:Thyroid hormones (THs) exert pleiotropic effects in different mammalian organs, including gonads. Genetic and non-genetic factors, such as ageing and environmental stressors (e.g., low-iodine intake, exposure to endocrine disruptors, etc.), can alter T4/T3 synthesis by the thyroid. In any case, peripheral T3, controll...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9061679
更新日期：2020-06-01 00:00:00
abstract：:Coronavirus disease 2019 (COVID-19), due to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become an epidemiological threat and a worldwide concern. SARS-CoV-2 has spread to 210 countries worldwide and more than 6,500,000 confirmed cases and 384,643 deaths have been reported, while the number of...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9061753
更新日期：2020-06-05 00:00:00
abstract：:Cholangiocarcinoma (CCA) arises from the biliary tract epithelium and accounts for 10-15% of all hepatobiliary malignancies. Depending on anatomic location, CCA is classified as intrahepatic (iCCA), perihilar (pCCA) and distal (dCCA). The best treatment option for pCCA is liver resection and when a radical oncological...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9051353
更新日期：2020-05-05 00:00:00
abstract：:Oral diseases are considered the most common noncommunicable diseases and are related to serious local and systemic disorders. Oral pathogens can grow and spread in the oral mucosae and frequently in biomaterials (e.g., dentures or prostheses) under polymicrobial biofilms, leading to several disorders such as dental c...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9020517
更新日期：2020-02-14 00:00:00
abstract：:An improvement in negative symptoms and a reduction in the number of visits to the emergency department have been reported in a problem solving based psychoeducational group intervention (PE) for adolescents with psychosis relative to a nonstructured group (NS). One of the factors that may play a role on the response ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8122108
更新日期：2019-12-02 00:00:00
abstract：:Limited evidence is available comparing the differences between pre-operative and post-operative 3D implant positions from the viewpoint of prosthetics. We aimed to investigate the differences between preplanned positions of virtual provisional restorations and their actual positions following fully guided single-impl...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8040490
更新日期：2019-04-11 00:00:00
abstract：BACKGROUND:Hand osteoarthritis (OA) is one of the most common joint diseases, but studies on biomarkers are rare. The aim of this explorative study was (a) to evaluate potential biomarkers of hand OA, (b) to identify an optimal time point to sample venous blood, and (c) to correlate biomarker levels with radiological a...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8101545
更新日期：2019-09-26 00:00:00
abstract：:Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in older populations in industrialized nations. AMD is a late-onset deterioration of photoreceptors and retinal pigment epithelium in the central retina caused by various environmental and genetic factors. Great strides i...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm4020343
更新日期：2015-02-12 00:00:00
abstract：:Fibrillary glomerulonephritis (FGN) is a rare glomerular disease characterized by glomerular deposition of randomly arranged non-amyloid fibrils. FGN has a poor renal prognosis and its optimal treatment is a medical challenge. Rituximab therapy has recently emerged as a promising approach even though its mechanism of ...
journal_title：Journal of clinical medicine
pub_type：
doi：10.3390/jcm7110430
更新日期：2018-11-09 00:00:00
abstract：:Decompensated cirrhosis predisposes to infectious diseases and acute-on-chronic liver failure (ACLF) in critically ill patients. Infections like spontaneous bacterial peritonitis (SBP) are frequently associated with multi-organ failure and increased mortality. Consequently, reliable predictors of outcome and early dia...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9092865
更新日期：2020-09-04 00:00:00
abstract：:There is no treatment of choice for irritable bowel syndrome, which affects up to 20% of school-aged children. This cross-sectional study evaluated the difference in the average vitamin D level between subtypes of irritable bowel syndrome, and the relationship between the vitamin D level as well as the severity of irr...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm7120500
更新日期：2018-12-01 00:00:00
abstract：:: Direct energy deposition (DED) technology has gained increasing attention as a new implant surface technology that replicates the porous structure of natural bones facilitating osteoblast colonization and bone ingrowth. However, concerns have arisen over osteolysis or chronic inflammation that could be caused by Cob...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9020478
更新日期：2020-02-09 00:00:00
abstract：:The aim of this study was to investigate the prescribing cascade phenomenon of dopaminergic drugs such as levodopa in the management of gastroprokinetic drugs induced parkinsonism. Based on the Korea National Health Insurance Service (NHIS)-Senior Cohort Database, we analyzed patients aged ≥65 years, between 2009 and ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8091496
更新日期：2019-09-19 00:00:00
abstract：:Pancreatic ductal adenocarcinoma (PDA) is notorious for its poor prognosis. The current mainstay of treatment for PDA is surgical resection followed by adjuvant chemotherapy. However, it is difficult to predict the post-operative outcome because of the lack of reliable markers. The single-nucleotide polymorphism (SNP)...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8122225
更新日期：2019-12-16 00:00:00
abstract：:Despite the overall success of cochlear implantation, language outcomes remain suboptimal and subject to large inter-individual variability. Early auditory rehabilitation techniques have mostly focused on low-level sensory abilities. However, a new body of literature suggests that cognitive operations are critical for...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9041058
更新日期：2020-04-08 00:00:00
abstract：:Successful implementation of postpartum lifestyle interventions first requires the identification of effective core components, such as strategies for behavioural change. This systematic review and meta-analysis aimed to describe the associations between behavioural strategies and changes in weight, diet, and physical...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9010237
更新日期：2020-01-16 00:00:00
abstract：:Drug-induced immune thrombocytopenia (DITP) is a life-threatening clinical syndrome that is under-recognized and difficult to diagnose. Many drugs can cause immune-mediated thrombocytopenia, but the most commonly implicated are abciximab, carbamazepine, ceftriaxone, eptifibatide, heparin, ibuprofen, mirtazapine, oxali...
journal_title：Journal of clinical medicine
pub_type： 杂志文章,评审
doi：10.3390/jcm9072212
更新日期：2020-07-13 00:00:00
abstract：:Patients with rheumatoid arthritis (RA) may experience residual pain and functional impairment despite good control of disease activity. This study compared improvements in pain and physical function in patients with well-controlled RA after 24 weeks' treatment with baricitinib, adalimumab or placebo in the 52-week RA...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8091394
更新日期：2019-09-05 00:00:00
abstract：:Information on Lyme borreliosis (LB) during pregnancy is limited. In the present study, the course and outcome of erythema migrans (EM) in 304 pregnant women, diagnosed in the period 1990-2015, was assessed and compared with that in age-matched non-pregnant women. The frequency of unfavorable outcome of pregnancies wa...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9082364
更新日期：2020-07-24 00:00:00
abstract：:Obstructive sleep apnea (OSA) is a chronic and prevalent disorder, strongly associated with cardiovascular disease (CVD). The apnea-hypopnea index (AHI), or respiratory event index (REI), and the oxygen desaturation index (ODI) are the clinical metrics of sleep apnea in terms of diagnosis and severity. However, AHI, o...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9082475
更新日期：2020-08-01 00:00:00
abstract：:The vaginal microbiota plays a critical role in pregnancy. Bacteria from Lactobacillus spp. are thought to maintain immune homeostasis and modulate the inflammatory responses against pathogens implicated in cervical shortening, one of the risk factors for spontaneous preterm birth. We studied vaginal microbiota in 46 ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9113621
更新日期：2020-11-10 00:00:00
abstract：BACKGROUND:Patients with diabetic kidney disease (DKD) are at higher risk of hypoglycemia than diabetic patients without DKD. We aimed to investigate the temporal trends of severe hypoglycemia in advanced DKD patients transitioning to dialysis and examine risk factors associated with severe hypoglycemia. We also invest...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8040420
更新日期：2019-03-27 00:00:00
abstract：:Conventional 3D multicellular tumor spheroids of head and neck squamous cell carcinoma (HNSCC) consisting exclusively of cancer cells have some limitations. They are compact cell aggregates that do not interact with their extracellular milieu, thus suffering from both insufficient extracellular matrix (ECM) deposition...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8101686
更新日期：2019-10-15 00:00:00
abstract：BACKGROUND AND AIMS:The Multidimensional Prognostic Index (MPI), an objective and quantifiable tool based on the Comprehensive Geriatric Assessment, has been shown to predict adverse outcomes in European cohorts. We conducted a validation study of the original MPI, and of adapted versions that accounted for the use of ...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8111820
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:There are limited data for non-vitamin K antagonist oral anticoagulants (NOACs) impact on outcomes for patients with atrial fibrillation (AF) and valvular heart diseases (VHDs). METHODS:We identified patients with AF and associated Evaluated Heartvalves, Rheumatic or Artificial (EHRA) type 2 VHDs, and who h...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8101624
更新日期：2019-10-04 00:00:00
abstract：:The aim of this study is to determine the accuracy of adrenal vein sampling (AVS) with and without adrenocorticotropic hormone (ACTH) stimulation to distinguish between unilateral and bilateral primary hyperaldosteronism (PA). Retrospective analysis of a prospective database from a referral center between 1984 and 200...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9051447
更新日期：2020-05-13 00:00:00
abstract：:The aim of the study was to examine the usefulness of targeted musculoskeletal ultrasonography (MSUS) in assessing the disease activity of patients with early inflammatory arthritis (EIA). Twenty-eight patients with EIA were enrolled. The MSUS examination of joints with arthritic signs (tenderness or swelling), measur...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm10020283
更新日期：2021-01-14 00:00:00
abstract：OBJECTIVE:To analyze the difference in the prevalence of sexually transmitted infections (STIs) between two time periods (2000⁻2007 and 2008⁻2014, with the latter period characterized by the economic crisis), as well as determine differences in sociodemographic factors, clinical care, and risk indicators. METHODS:This...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm8020277
更新日期：2019-02-25 00:00:00
abstract：:The purpose of this study was to investigate the relationship between the retinal pigment epithelium (RPE) and outer retina changes, expressed in terms of sub-RPE illumination (SRI) on optical-coherence tomography (OCT), and central retinal function, measured by visual acuity and focal electroretinogram (fERG), in pat...
journal_title：Journal of clinical medicine
pub_type： 杂志文章
doi：10.3390/jcm9092973
更新日期：2020-09-15 00:00:00
