当前位置： SCI文献检索 > Journal of Clinical Medicine期刊下所有文献 > Validation and Adaptation of the Multidimensional Prognostic Index in an Older Australian Cohort.

Validation and Adaptation of the Multidimensional Prognostic Index in an Older Australian Cohort.

Abstract：

BACKGROUND AND AIMS:The Multidimensional Prognostic Index (MPI), an objective and quantifiable tool based on the Comprehensive Geriatric Assessment, has been shown to predict adverse outcomes in European cohorts. We conducted a validation study of the original MPI, and of adapted versions that accounted for the use of specific drugs and cultural diversity in the assessment of cognition, in older Australians. METHODS:The capacity of the MPI to predict 12-month mortality was assessed in 697 patients (median age: 80 years; interquartile range: 72-86) admitted to a metropolitan teaching hospital between September 2015 and February 2017. RESULTS:In simple logistic regression analysis, the MPI was associated with 12-month mortality (Low risk: OR reference group; moderate risk: OR 2.50, 95% CI: 1.67-3.75; high risk: OR 4.24, 95% CI: 2.28-7.88). The area under the receiver operating characteristic curve (AUC) for the unadjusted MPI was 0.61 (0.57-0.65) and 0.64 (95% CI: 0.59-0.68) with age and sex adjusted. The adapted versions of the MPI did not significantly change the AUC of the original MPI. CONCLUSION:The original and adapted MPI were strongly associated with 12-month mortality in an Australian cohort. However, the discriminatory performance was lower than that reported in European studies.

journal_name

J Clin Med

journal_title

Journal of clinical medicine

authors

Bryant K,Sorich MJ,Woodman RJ,Mangoni AA

doi

10.3390/jcm8111820

subject

Has Abstract

pub_date

2019-11-01 00:00:00

issue

11

issn

2077-0383

pii

jcm8111820

journal_volume

8

pub_type

杂志文章

相关文献

Journal of Clinical Medicine文献大全
  • Simplified Diagnosis of Critical Illness Polyneuropathy in Patients with Prolonged Mechanical Ventilation: A Prospective Observational Cohort Study.

    abstract：BACKGROUND:Although early identification of critical illness polyneuropathy (CIP) is necessary, the established diagnostic criteria have several limitations in the intensive care unit (ICU) setting. The purpose of this study was to define simplified diagnostic criteria of CIP that best predict clinical outcomes. METHO...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9124029

    authors： Jung C,Choi NJ,Kim WJ,Chun YM,Lee HJ,Kim TH,Pak SR,Lee JH,Hong SK,Kim W

    更新日期：2020-12-13 00:00:00

  • Plasma C-Peptide and Risk of Developing Type 2 Diabetes in the General Population.

    abstract：:C-peptide measurement may represent a better index of pancreatic β-cell function compared to insulin. While insulin is mainly cleared by liver, C-peptide is mainly metabolized by kidneys. The aim of our study was to evaluate the association between baseline plasma C-peptide level and the development of type 2 diabetes...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9093001

    authors： Sokooti S,Kieneker LM,Borst MH,Muller Kobold A,Kootstra-Ros JE,Gloerich J,van Gool AJ,Heerspink HJL,T Gansevoort R,Dullaart RPF,Bakker SJL

    更新日期：2020-09-17 00:00:00

  • Survivorship in Colorectal Cancer: A Cohort Study of the Patterns and Documented Content of Follow-Up Visits.

    abstract：:Survivors of colorectal cancer (CRC) may experience a range of physical, psychosocial, and practical challenges as a consequence of their diagnosis. We assessed the patterns and documented content of follow-up visits within the first three years following treatment, in comparison to survivorship care guidelines. Survi...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9092725

    authors： Garwood V,Lisy K,Jefford M

    更新日期：2020-08-24 00:00:00

  • Variable Responses to Corneal Grafts: Insights from Immunology and Systems Biology.

    abstract：:Corneal grafts interact with their hosts via complex immunobiological processes that sometimes lead to graft failure. Prediction of graft failure is often a tedious task due to the genetic and nongenetic heterogeneity of patients. As in other areas of medicine, a reliable prediction method would impact therapeutic dec...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9020586

    authors： Di Zazzo A,Lee SM,Sung J,Niutta M,Coassin M,Mashaghi A,Inomata T

    更新日期：2020-02-21 00:00:00

  • Tadalafil 5 mg Alone or in Combination with Tamsulosin 0.4 mg for the Management of Men with Lower Urinary Tract Symptoms and Erectile Dysfunction: Results of a Prospective Observational Trial.

    abstract：:Tadalafil 5 mg represents the standard for men with Erectile dysfunction (ED) and lower urinary tract symptoms (LUTS)/benign prostatic enlargement (BPE). We carried out an observational trial aiming to assess the efficacy and safety of Tadalafil compared with Tadalafil plus Tamsulosin. Seventy-five patients complainin...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8081126

    authors： Sebastianelli A,Spatafora P,Frizzi J,Saleh O,Sessa M,De Nunzio C,Tubaro A,Vignozzi L,Maggi M,Serni S,McVary KT,Kaplan SA,Gravas S,Chapple C,Gacci M

    更新日期：2019-07-29 00:00:00

  • The Role of Alcohol Metabolism in the Pathology of Alcohol Hangover.

    abstract：:The limited number of available studies that examined the pathology of alcohol hangover focused on biomarkers of alcohol metabolism, oxidative stress and the inflammatory response to alcohol as potentially important determinants of hangover severity. The available literature on alcohol metabolism and oxidative stress ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9113421

    authors： Mackus M,Loo AJV,Garssen J,Kraneveld AD,Scholey A,Verster JC

    更新日期：2020-10-25 00:00:00

  • Liquid Biopsy for the Detection of Resistance Mechanisms in NSCLC: Comparison of Different Blood Biomarkers.

    abstract：:The use of targeted agents and immunotherapy for the treatment of advanced non-small-cell lung cancer (NSCLC) has made it mandatory to characterize tumor tissue for patient selection. Moreover, the development of agents that are active against specific resistance mechanisms arising during treatment make it equally imp...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm8070998

    authors： Pasini L,Ulivi P

    更新日期：2019-07-09 00:00:00

  • Prevalence, Risk Factors and Course of Osteoporosis in Patients with Crohn's Disease at a Tertiary Referral Center.

    abstract：BACKGROUND:Patients with Crohn's disease are at increased risk for fractures due to low bone mineral density (BMD). Real-world data are necessary to optimize surveillance and treatment strategies. METHODS:Patients with Crohn's disease who underwent at least one dual-energy X-ray absorptiometry (DXA) scans were recruit...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8122178

    authors： Hoffmann P,Krisam J,Kasperk C,Gauss A

    更新日期：2019-12-10 00:00:00

  • Factors Associated with Decisions for Initial Dosing, Up-Titration of Propiverine and Treatment Outcomes in Overactive Bladder Syndrome Patients in a Non-Interventional Setting.

    abstract：:Two doses of propiverine ER (30 and 45 mg/d) are available for the treatment of overactive bladder (OAB) syndrome. We have explored factors associated with the initial dosing choice (allocation bias), the decision to adapt dosing (escalation bias) and how dosing relative to other factors affects treatment outcomes. Da...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm10020311

    authors： Amiri M,Schneider T,Oelke M,Murgas S,Michel MC

    更新日期：2021-01-15 00:00:00

  • A Simulation on Potential Secondary Spread of Novel Coronavirus in an Exported Country Using a Stochastic Epidemic SEIR Model.

    abstract：:Ongoing outbreak of pneumonia caused by novel coronavirus (2019-nCoV) began in December 2019 in Wuhan, China, and the number of new patients continues to increase. Even though it began to spread to many other parts of the world, such as other Asian countries, the Americas, Europe, and the Middle East, the impact of se...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9040944

    authors： Iwata K,Miyakoshi C

    更新日期：2020-03-30 00:00:00

  • Epileptic Seizures in Critically Ill Patients: Diagnosis, Management, and Outcomes.

    abstract：:Epileptic seizures in critically ill patients represent a major source of concern, because they are associated with significant mortality and morbidity rates. Despite recent advances that have enabled a better understanding of the global epidemiology of this entity, epileptic seizures in critically ill patients remain...

    journal_title：Journal of clinical medicine

    pub_type： 社论

    doi：10.3390/jcm9072218

    authors： Holleville M,Jacq G,Perier F,Fontaine C,Legriel S

    更新日期：2020-07-13 00:00:00

  • Review of Pharmacological Strategies with Repurposed Drugs for Hereditary Hemorrhagic Telangiectasia Related Bleeding.

    abstract：:The diagnosis of hereditary hemorrhagic telangiectasia (HHT) is based on the Curaçao criteria: epistaxis, telangiectases, arteriovenous malformations in internal organs, and family history. Genetically speaking, more than 90% of HHT patients show mutations in ENG or ACVRL1/ALK1 genes, both belonging to the TGF-β/BMP9 ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9061766

    authors： Albiñana V,Cuesta AM,Rojas-P I,Gallardo-Vara E,Recio-Poveda L,Bernabéu C,Botella LM

    更新日期：2020-06-06 00:00:00

  • Automated Nociceptive Withdrawal Reflex Measurements Reveal Normal Reflex Thresholds and Augmented Pain Ratings in Patients with Fibromyalgia.

    abstract：:The nociceptive withdrawal reflex (NWR) is used to probe spinal cord excitability in chronic pain states. Here, we used an automated and unbiased procedure for determining the NWR threshold and compared the reflex thresholds and corresponding pain ratings in a well-characterized cohort of fibromyalgia (n = 29) and mat...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9061992

    authors： Ydrefors J,Karlsson T,Wentzel Olausson U,Ghafouri B,Johansson AC,Olausson H,Gerdle B,Nagi SS

    更新日期：2020-06-25 00:00:00

  • Biochemical Assessment and Monitoring of Mitochondrial Disease.

    abstract：:Mitochondrial respiratory chain (MRC) disorders have a multifaceted clinical presentation and genetic origin[...]. ...

    journal_title：Journal of clinical medicine

    pub_type： 社论

    doi：10.3390/jcm7040066

    authors： Hargreaves IP

    更新日期：2018-03-29 00:00:00

  • Novel Insights into the Role of UBE3A in Regulating Apoptosis and Proliferation.

    abstract：:The UBE3A gene codes for a protein with two known functions, a ubiquitin E3-ligase which catalyzes ubiquitin binding to substrate proteins and a steroid hormone receptor coactivator. UBE3A is most famous for its critical role in neuronal functioning. Lack of UBE3A protein expression leads to Angelman syndrome (AS), wh...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9051573

    authors： Simchi L,Panov J,Morsy O,Feuermann Y,Kaphzan H

    更新日期：2020-05-22 00:00:00

  • Recent Insights into the Control of Human Papillomavirus (HPV) Genome Stability, Loss, and Degradation.

    abstract：:Most human papillomavirus (HPV) antiviral strategies have focused upon inhibiting viral DNA replication, but it is increasingly apparent that viral DNA levels can be chemically controlled by approaches that promote its instability. HPVs and other DNA viruses have a tenuous relationship with their hosts. They must repl...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm4020204

    authors： Fisher C

    更新日期：2015-01-01 00:00:00

  • RNAs and Gene Expression Predicting Postoperative Atrial Fibrillation in Cardiac Surgery Patients Undergoing Coronary Artery Bypass Grafting.

    abstract：:Postoperative atrial fibrillation (POAF) is linked with increased morbidity, mortality rate and financial liability. About 20-50% of patients experience POAF after coronary artery bypass graft (CABG) surgery. Numerous review articles and meta-analyses have investigated links between patient clinical risk factors, demo...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9041139

    authors： Khan MS,Yamashita K,Sharma V,Ranjan R,Dosdall DJ

    更新日期：2020-04-16 00:00:00

  • Bortezomib Treatment Modulates Autophagy in Multiple Myeloma.

    abstract：:Although the introduction of bortezomib as a therapeutic strategy has improved the overall survival of multiple myeloma (MM) patients, 15-20% of high-risk patients do not respond to bortezomib over time or become resistant to treatment. Therefore, the development of new therapeutic strategies, such as combination ther...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9020552

    authors： Di Lernia G,Leone P,Solimando AG,Buonavoglia A,Saltarella I,Ria R,Ditonno P,Silvestris N,Crudele L,Vacca A,Racanelli V

    更新日期：2020-02-18 00:00:00

  • Diagnosis and Management of Autoimmune Hemolytic Anemia in Patients with Liver and Bowel Disorders.

    abstract：:Anemia is a common feature of liver and bowel diseases. Although the main causes of anemia in these conditions are represented by gastrointestinal bleeding and iron deficiency, autoimmune hemolytic anemia should be considered in the differential diagnosis. Due to the epidemiological association, autoimmune hemolytic a...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm10030423

    authors： Bianco C,Coluccio E,Prati D,Valenti L

    更新日期：2021-01-22 00:00:00

  • Effect of Bladder Neck Preservation on Long-Term Urinary Continence after Robot-Assisted Laparoscopic Prostatectomy: A Systematic Review and Meta-Analysis.

    abstract：:This study aimed to evaluate the effect of bladder neck preservation (BNP) on long-term urinary continence after robot-assisted laparoscopic prostatectomy (RALP). We systematically searched the PubMed, Embase, and Cochrane Library databases to identify studies that assessed the difference in urinary continence and onc...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm8122068

    authors： Kim JW,Kim DK,Ahn HK,Jung HD,Lee JY,Cho KS

    更新日期：2019-11-24 00:00:00

  • NT5E/CD73 as Correlative Factor of Patient Survival and Natural Killer Cell Infiltration in Glioblastoma.

    abstract：:CD73, a cell-surface protein encoded by the gene NT5E, is overexpressed in glioblastoma (GBM), where it contributes to the tumor's pathophysiology via the generation of immunosuppressive adenosine. Adenosinergic signaling, in turn, drives immunosuppression of natural killer (NK) cells through metabolic and functional ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8101526

    authors： Wang J,Matosevic S

    更新日期：2019-09-23 00:00:00

  • Serum Zinc Level and non-Protein Respiratory Quotient in Patients with Chronic Liver Diseases.

    abstract：:We sought to clarify the correlation between non-protein respiratory quotient (npRQ) in indirect calorimetry and serum zinc (Zn) level in chronic liver diseases (CLDs, n = 586, 309 liver cirrhosis (LC) patients, median age = 63 years). Clinical parameters potentially linked to npRQ <0.85 (best cutoff point for the pro...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9010255

    authors： Nishikawa H,Takata R,Enomoto H,Yoh K,Iwata Y,Sakai Y,Kishino K,Shimono Y,Ikeda N,Takashima T,Aizawa N,Hasegawa K,Ishii N,Yuri Y,Nishimura T,Iijima H,Nishiguchi S

    更新日期：2020-01-17 00:00:00

  • Modified Split-Scan Computed Tomography (CT) Diagnostics of Severely Injured Patients: First Results from a Level I Trauma Center Using a Dedicated Head-and-Neck CT-Angiogram for the Detection of Cervical Artery Dissections.

    abstract：INTRODUCTION:Traumatic cervical artery dissections are associated with high mortality and morbidity in severely injured patients. After finding even higher incidences than reported before, we decided to incorporate a dedicated head-and-neck computed tomography angiogram (CT-A) in our imaging routine for patients who ha...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9082568

    authors： Popp D,Thiedemann C,Bäumler W,Ernstberger A,Alt V,Schicho A

    更新日期：2020-08-08 00:00:00

  • Influence of Fixation Methods on Prosthetic Joint Infection Following Primary Total Knee Replacement: Meta-Analysis of Observational Cohort and Randomised Intervention Studies.

    abstract：:The type of fixation used in primary total knee replacement (TKR) may influence the risk of prosthetic joint infection (PJI). We conducted a systematic review and meta-analysis to assess published evidence linking type of fixation (cemented, uncemented, or hybrid) with the risk of PJI following primary TKR. Randomised...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8060828

    authors： Kunutsor SK,Wylde V,Whitehouse MR,Beswick AD,Lenguerrand E,Blom AW

    更新日期：2019-06-11 00:00:00

  • Ultrasound Imaging for the Cutaneous Nerves of the Extremities and Relevant Entrapment Syndromes: From Anatomy to Clinical Implications.

    abstract：:Cutaneous nerve entrapment plays an important role in neuropathic pain syndrome. Due to the advancement of ultrasound technology, the cutaneous nerves can be visualized by high-resolution ultrasound. As the cutaneous nerves course superficially in the subcutaneous layer, they are vulnerable to entrapment or collateral...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm7110457

    authors： Chang KV,Mezian K,Naňka O,Wu WT,Lou YM,Wang JC,Martinoli C,Özçakar L

    更新日期：2018-11-21 00:00:00

  • Alternative Erythropoietin Receptors in the Nervous System.

    abstract：:In addition to its regulatory function in the formation of red blood cells (erythropoiesis) in vertebrates, Erythropoietin (Epo) contributes to beneficial functions in a variety of non-hematopoietic tissues including the nervous system. Epo protects cells from apoptosis, reduces inflammatory responses and supports re-...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm7020024

    authors： Ostrowski D,Heinrich R

    更新日期：2018-02-02 00:00:00

  • Cardiac Output Evaluation on Septic Shock Patients: Comparison between Calibrated and Uncalibrated Devices during Vasopressor Therapy.

    abstract：:There are no reliable, non-invasive methods to accurately measure cardiac output (CO) in septic patients. MostCare (Vytech Health™, Vygon, Padova, Italy), is a beat-to-beat, self calibrated method for CO measurement based on continuous analysis of reflected arterial pressure waveforms. We enrolled 40 patients that wer...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm10020213

    authors： Persona P,Valeri I,Saraceni E,De Cassai A,Calabrese F,Navalesi P

    更新日期：2021-01-09 00:00:00

  • Brace Treatment for Adolescent Idiopathic Scoliosis.

    abstract：:In the past, numerous non-operative treatments for adolescent idiopathic scoliosis (AIS), including exercise, physical therapy, electrical stimulation, and brace treatment, have been tried to delay or prevent the curve progression. Of these, brace treatment is the only option that is widely accepted and has demonstrat...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm7060136

    authors： Kuroki H

    更新日期：2018-06-04 00:00:00

  • Long Daytime Napping Is Associated with Increased Adiposity and Type 2 Diabetes in an Elderly Population with Metabolic Syndrome.

    abstract：:Research examining associations between objectively-measured napping time and type 2 diabetes (T2D) is lacking. This study aimed to evaluate daytime napping in relation to T2D and adiposity measures in elderly individuals from the Mediterranean region. A cross-sectional analysis of baseline data from 2190 elderly part...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8071053

    authors： Papandreou C,Díaz-López A,Babio N,Martínez-González MA,Bulló M,Corella D,Fitó M,Romaguera D,Vioque J,Alonso-Gómez ÁM,Wärnberg J,Martínez AJ,Serra-Majem L,Estruch R,Fernández-García JC,Lapetra J,Pintó X,Tur JA,Garcia-R

    更新日期：2019-07-19 00:00:00

  • The Influence of Maternal-Foetal Parameters on Concentrations of Zonulin and Calprotectin in the Blood and Stool of Healthy Newborns during the First Seven Days of Life. An Observational Prospective Cohort Study.

    abstract：BACKGROUND:It can be hypothetically assumed that maternal and perinatal factors influence the intestinal barrier. METHODS:The study was conducted with 100 healthy, full-term newborns breastfed in the first week of life, with similar analyses for their mothers. Zonulin and calprotectin levels were used as intestinal pe...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8040473

    authors： Łoniewska B,Węgrzyn D,Adamek K,Kaczmarczyk M,Skonieczna-Żydecka K,Adler G,Jankowska A,Uzar I,Kordek A,Celewicz M,Łoniewski I

    更新日期：2019-04-07 00:00:00