Abstract:
:Postoperative atrial fibrillation (POAF) is linked with increased morbidity, mortality rate and financial liability. About 20-50% of patients experience POAF after coronary artery bypass graft (CABG) surgery. Numerous review articles and meta-analyses have investigated links between patient clinical risk factors, demographic conditions, and pre-, peri- and post-operative biomarkers to forecast POAF incidence in CABG patients. This narrative review, for the first time, summarize the role of micro-RNAs, circular-RNAs and other gene expressions that have shown experimental evidence to accurately predict the POAF incidence in cardiac surgery patients after CABG. We envisage that identifying specific genomic markers for predicting POAF might be a significant step for the prevention and effective management of this type of post-operative complication and may provide critical perspective into arrhythmogenic substrate responsible for POAF.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Khan MS,Yamashita K,Sharma V,Ranjan R,Dosdall DJdoi
10.3390/jcm9041139subject
Has Abstractpub_date
2020-04-16 00:00:00issue
4issn
2077-0383pii
jcm9041139journal_volume
9pub_type
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更新日期:2019-08-26 00:00:00
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