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COVID-19: Specific and Non-Specific Clinical Manifestations and Symptoms: The Current State of Knowledge.

Abstract：

:Coronavirus disease 2019 (COVID-19), due to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become an epidemiological threat and a worldwide concern. SARS-CoV-2 has spread to 210 countries worldwide and more than 6,500,000 confirmed cases and 384,643 deaths have been reported, while the number of both confirmed and fatal cases is continually increasing. COVID-19 is a viral disease that can affect every age group-from infants to the elderly-resulting in a wide spectrum of various clinical manifestations. COVID-19 might present different degrees of severity-from mild or even asymptomatic carriers, even to fatal cases. The most common complications include pneumonia and acute respiratory distress syndrome. Fever, dry cough, muscle weakness, and chest pain are the most prevalent and typical symptoms of COVID-19. However, patients might also present atypical symptoms that can occur alone, which might indicate the possible SARS-CoV-2 infection. The aim of this paper is to review and summarize all of the findings regarding clinical manifestations of COVID-19 patients, which include respiratory, neurological, olfactory and gustatory, gastrointestinal, ophthalmic, dermatological, cardiac, and rheumatologic manifestations, as well as specific symptoms in pediatric patients.

journal_name

J Clin Med

journal_title

Journal of clinical medicine

authors

Baj J,Karakuła-Juchnowicz H,Teresiński G,Buszewicz G,Ciesielka M,Sitarz E,Forma A,Karakuła K,Flieger W,Portincasa P,Maciejewski R

doi

10.3390/jcm9061753

subject

Has Abstract

pub_date

2020-06-05 00:00:00

issue

6

issn

2077-0383

pii

jcm9061753

journal_volume

9

pub_type

杂志文章,评审

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