当前位置： SCI文献检索 > Journal of Clinical Medicine期刊下所有文献 > Prediction of One-Year Mortality Based upon A New Staged Mortality Risk Model in Patients with Aortic Stenosis Undergoing Transcatheter Valve Replacement.

Prediction of One-Year Mortality Based upon A New Staged Mortality Risk Model in Patients with Aortic Stenosis Undergoing Transcatheter Valve Replacement.

Abstract：

BACKGROUND:In-depth knowledge about potential predictors of mortality in transcatheter aortic valve replacement (TAVR) is still warranted. Currently used risk stratification models for TAVR often fail to reach a holistic approach. We, therefore, aimed to create a new staged risk model for 1-year mortality including several new categories including (a) AS-entities (b) cardiopulmonary hemodynamics (c) comorbidities, and (d) different access routes. METHODS:737 transfemoral (TF) TAVR (84.3%) and 137 transapical (TA) TAVR (15.7%) patients were included. Predictors of 1-year mortality were assessed according to the aforementioned categories. RESULTS:Over-all 1-year mortality (n = 100, 11.4%) was significantly higher in the TA TAVR group (TF vs. TA TAVR: 10.0% vs. 18.9 %; p = 0.0050*). By multivariate cox-regression analysis, a three-staged model was created in patients with fulfilled categories (TF TAVR: n = 655, 88,9%; TA TAVR: n = 117, 85.4%). Patients in "stage 2" showed 1.7-fold (HR 1.67; CI 1.07-2.60; p = 0.024*) and patients in "stage 3" 3.5-fold (HR 3.45; CI 1.97-6.05; p < 0.0001*) enhanced risk to die within 1 year. Mortality increased with every stage and reached the highest rates of 42.5% in "stage 3" (plogrank < 0.0001*), even when old- and new-generation devices (plogrank = n.s) were sub-specified. CONCLUSIONS:This new staged mortality risk model had incremental value for prediction of 1-year mortality after TAVR independently from the TAVR-era.

journal_name

J Clin Med

journal_title

Journal of clinical medicine

authors

Veulemans V,Polzin A,Maier O,Klein K,Wolff G,Hellhammer K,Afzal S,Piayda K,Jung C,Westenfeld R,Blehm A,Lichtenberg A,Kelm M,Zeus T

doi

10.3390/jcm8101642

subject

Has Abstract

pub_date

2019-10-08 00:00:00

issue

10

issn

2077-0383

pii

jcm8101642

journal_volume

8

pub_type

杂志文章

相关文献

Journal of Clinical Medicine文献大全
  • Immunomodulation by an Omega-6 Fatty Acid Reduced Mixed Lipid Emulsion in Murine Acute Respiratory Distress Syndrome.

    abstract：BACKGROUND:Acute respiratory distress syndrome (ARDS) is associated with both high morbidity and mortality in intensive care units worldwide. Patients with ARDS often require parenteral nutrition with lipid emulsions as essential components. In the present study, we assessed the immunomodulatory and apoptotic effects o...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9072048

    authors： Hecker M,Rose M,Hecker A,Dietrich H,Schaefer MB,Sommer N,Seeger W,Mayer K

    更新日期：2020-06-29 00:00:00

  • Clusterin as a New Marker of Kidney Injury in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation-A Pilot Study.

    abstract：BACKGROUND AND AIMS:The markers of renal damage defining subclinical AKI are not widely used in children undergoing allogeneic hematopoietic stem cell transplantation (alloHSCT). The aim of the study was to evaluate serum and urinary clusterin as indices of kidney injury after alloHSCT in relation to damage (kidney inj...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9082599

    authors： Musiał K,Augustynowicz M,Miśkiewicz-Migoń I,Kałwak K,Ussowicz M,Zwolińska D

    更新日期：2020-08-11 00:00:00

  • Prevalence of ADHD in Accident Victims: Results of the PRADA Study.

    abstract：BACKGROUND:Recent research has shown an increased risk of accidents and injuries in ADHD patients, which could potentially be reduced by stimulant treatment. Therefore, the first aim of our study was to evaluate the prevalence of adult ADHD in a trauma surgery population. The second aim was to investigate accident mech...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8101643

    authors： Kittel-Schneider S,Wolff S,Queiser K,Wessendorf L,Meier AM,Verdenhalven M,Brunkhorst-Kanaan N,Grimm O,McNeill R,Grabow S,Reimertz C,Nau C,Klos M,Reif A

    更新日期：2019-10-08 00:00:00

  • The Loop Tenodesis Procedure-From Biomechanics to First Clinical Results.

    abstract：:(1) Introduction: Several surgical therapy options for the treatment of pathologies of the long biceps tendon (LHB) have been established. However, tenotomy, as well as established tenodesis techniques, has disadvantages, such as cosmetic deformities, functional impairments and residual shoulder pain. This study prese...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm10030432

    authors： Riedl M,Mayr A,Greiner S,Pfeifer C,Weiss I,Forchhammer L,Alt V,Kerschbaum M

    更新日期：2021-01-23 00:00:00

  • Tricyclic Antidepressant Use and Risk of Fractures: A Meta-Analysis of Cohort Studies through the Use of Both Frequentist and Bayesian Approaches.

    abstract：BACKGROUND:Research findings regarding the association between tricyclic antidepressant (TCA) treatment and the risk of fracture are not consistent; we aimed to assess whether people who take TCAs are at an increased fracture risk. METHODS:Relevant studies published through June 2020 were identified through database s...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9082584

    authors： Wu Q,Xu Y,Bao Y,Alvarez J,Gonzales ML

    更新日期：2020-08-10 00:00:00

  • First Time Seizure in the Setting of a Congenital Heart Abnormality and MCA Mycotic Aneurysms.

    abstract：:A 37 year-old man presented to the Emergency Department (ED) with new onset seizure and fall from standing.[...]. ...

    journal_title：Journal of clinical medicine

    pub_type：

    doi：10.3390/jcm5040046

    authors： Minckler MR,Curry M,Mosier JM

    更新日期：2016-04-12 00:00:00

  • Mixed Neuroendocrine Non-Neuroendocrine Neoplasms: A Systematic Review of a Controversial and Underestimated Diagnosis.

    abstract：:Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) represent a rare diagnosis of the gastro-entero-pancreatic tract. Evidence from the current literature regarding their epidemiology, biology, and management is of variable quality and conflicting. Based on available data, the MiNEN has an aggressive biological...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9010273

    authors： Frizziero M,Chakrabarty B,Nagy B,Lamarca A,Hubner RA,Valle JW,McNamara MG

    更新日期：2020-01-19 00:00:00

  • Effects of Mind⁻Body Exercises (Tai Chi/Yoga) on Heart Rate Variability Parameters and Perceived Stress: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.

    abstract：BACKGROUND:Heart rate variability (HRV) as an accurate, noninvasive measure of the Autonomous Nervous System (ANS) can reflect mental health (e.g., stress, depression, or anxiety). Tai Chi and Yoga (Tai Chi/Yoga), as the most widely practiced mind⁻body exercises, have shown positive outcomes of mental health. To date, ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm7110404

    authors： Zou L,Sasaki JE,Wei GX,Huang T,Yeung AS,Neto OB,Chen KW,Hui SS

    更新日期：2018-10-31 00:00:00

  • Comparison of Minimal Residual Disease Detection by Multiparameter Flow Cytometry, ASO-qPCR, Droplet Digital PCR, and Deep Sequencing in Patients with Multiple Myeloma Who Underwent Autologous Stem Cell Transplantation.

    abstract：:Multiple myeloma (MM) is a hematological malignancy with a poor prognosis, characterized by clonal proliferation of plasma cells in the bone marrow (BM). Relapse due to undetected minimal residual disease (MRD) is the leading cause of death among patients with MM. This review summarizes the methods and prognostic valu...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm6100091

    authors： Takamatsu H

    更新日期：2017-09-25 00:00:00

  • Identification of Vaginal Microbial Communities Associated with Extreme Cervical Shortening in Pregnant Women.

    abstract：:The vaginal microbiota plays a critical role in pregnancy. Bacteria from Lactobacillus spp. are thought to maintain immune homeostasis and modulate the inflammatory responses against pathogens implicated in cervical shortening, one of the risk factors for spontaneous preterm birth. We studied vaginal microbiota in 46 ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9113621

    authors： Di Paola M,Seravalli V,Paccosi S,Linari C,Parenti A,De Filippo C,Tanturli M,Vitali F,Torcia MG,Di Tommaso M

    更新日期：2020-11-10 00:00:00

  • Non-Pharmacological Interventions for Post-Stroke Fatigue: Systematic Review and Network Meta-Analysis.

    abstract：:Post-stroke fatigue (PSF) is one of the most serious sequelae, which often interferes with the rehabilitation process and impairs the functional recovery of patients. Due to insufficient evidence, it is unclear which specific pharmacological interventions should be recommended. Therefore, in this paper, we compare the...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9030621

    authors： Su Y,Yuki M,Otsuki M

    更新日期：2020-02-25 00:00:00

  • Implications of an Autism Spectrum Disorder Diagnosis: An Interview Study of How Physicians Experience the Diagnosis in a Young Child.

    abstract：:Clinicians are significant translators and interpreters towards parents of the abundant literature on autism spectrum disorder (ASD). However, how clinicians experience and view ASD and an ASD diagnosis is not well known. Sixteen physicians working with young children with a (presumed) diagnosis of ASD participated in...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm7100348

    authors： Jacobs D,Steyaert J,Dierickx K,Hens K

    更新日期：2018-10-12 00:00:00

  • Identification of Diagnostic and Prognostic microRNAs for Recurrent Vitreous Hemorrhage in Patients with Proliferative Diabetic Retinopathy.

    abstract：:MicroRNAs (miRNAs) can provide insight into the pathophysiological states of ocular tissues such as proliferative diabetic retinopathy (PDR). In this study, differences in miRNA expression in vitreous from PDR patients with and without incidence of recurrent vitreous hemorrhage (RVH) after the initial pars-plana vitre...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8122217

    authors： Mammadzada P,Bayle J,Gudmundsson J,Kvanta A,André H

    更新日期：2019-12-15 00:00:00

  • Effects of Dapagliflozin on Volume Status When Added to Renin-Angiotensin System Inhibitors.

    abstract：:Sodium glucose co-transporter 2 (SGLT2) inhibitors reduce the risk of heart and kidney failure in patients with type 2 diabetes, possibly due to diuretic effects. Previous non-placebo-controlled studies with SGLT2 inhibitors observed changes in volume markers in healthy individuals and in patients with type 2 diabetes...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8060779

    authors： Eickhoff MK,Dekkers CCJ,Kramers BJ,Laverman GD,Frimodt-Møller M,Jørgensen NR,Faber J,Danser AHJ,Gansevoort RT,Rossing P,Persson F,Heerspink HJL

    更新日期：2019-05-31 00:00:00

  • SOX2 Expression Is an Independent Predictor of Oral Cancer Progression.

    abstract：:Potentially malignant oral lesions, mainly leukoplakia, are common. Malignant transformation varies widely, even in the absence of histological features such as dysplasia. Hence, there is a need for novel biomarker-based systems to more accurately predict the risk of cancer progression. The pluripotency transcription ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8101744

    authors： de Vicente JC,Donate-Pérez Del Molino P,Rodrigo JP,Allonca E,Hermida-Prado F,Granda-Díaz R,Rodríguez Santamarta T,García-Pedrero JM

    更新日期：2019-10-21 00:00:00

  • The Predictive Value of Low Skeletal Muscle Mass Assessed on Cross-Sectional Imaging for Anti-Cancer Drug Toxicity: A Systematic Review and Meta-Analysis.

    abstract：:Low skeletal muscle mass (LSMM) is increasingly recognized for its predictive value for adverse events in cancer patients. In specific, the predictive value of LSMM has been demonstrated for anti-cancer drug toxicity in a variety of cancer types and anti-cancer drugs. However, due to the limited sample size and study ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9113780

    authors： Huiskamp LFJ,Chargi N,Devriese LA,May AM,Huitema ADR,de Bree R

    更新日期：2020-11-23 00:00:00

  • Hyponatraemia in Emergency Medical Admissions-Outcomes and Costs.

    abstract：:Healthcare systems in the developed world are struggling with the demand of emergency room presentations; the study of the factors driving such demand is of fundamental importance. From a database of all emergency medical admissions (66,933 episodes in 36,271 patients) to St James' Hospital, Dublin, Ireland, over 12 y...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm3041220

    authors： Conway R,Byrne D,O'Riordan D,Silke B

    更新日期：2014-10-29 00:00:00

  • Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data.

    abstract：:The geographic spread of 2019 novel coronavirus (COVID-19) infections from the epicenter of Wuhan, China, has provided an opportunity to study the natural history of the recently emerged virus. Using publicly available event-date data from the ongoing epidemic, the present study investigated the incubation period and ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9020538

    authors： Linton NM,Kobayashi T,Yang Y,Hayashi K,Akhmetzhanov AR,Jung SM,Yuan B,Kinoshita R,Nishiura H

    更新日期：2020-02-17 00:00:00

  • Help-Seeking in Suicidal Situations: Paramount and yet Challenging. Interactions between Significant Others of Suicidal Persons and Health Care Providers.

    abstract：:Significant others are often crucial for suicidal persons or suicide attempters' access to care, yet little is known about their efforts to seek help. This article presents the findings of a qualitative pilot study carried out in Switzerland on the help-seeking process of 18 significant others, their perception of the...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm6020017

    authors： Castelli Dransart DA,Guerry S

    更新日期：2017-02-13 00:00:00

  • Comparative In Vitro Study of Various α2-Adrenoreceptor Agonist Drugs for Ticagrelor Reversal.

    abstract：:Ticagrelor, an antiplatelet adenosine diphosphate (ADP)-P2Y12 receptor antagonist, increases the risk of bleeding. Its management is challenging because platelet transfusion is ineffective and no specific antidote is currently available. Epinephrine, a vasopressor catecholamine prescribed during shock, restores platel...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9030809

    authors： Porta Bonete G,Godier A,Gaussem P,Belleville-Rolland T,Leuci A,Poirault-Chassac S,Bachelot-Loza C,Martin AC

    更新日期：2020-03-16 00:00:00

  • A New Method of Measuring the Volumetric Change of Alveolar Bone Around Dental Implants Using Computed Tomography.

    abstract：:This study proposes a method for measuring the volumetric change of alveolar bone after dental implant surgery using computed tomography (CT). A total of 40 implants in 20 patients (15 males and 5 females) were selected. The types of implants used were group 1: 24 CMI IS-II Active implants (Neobiotech Co., Seoul, Repu...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9041238

    authors： Lim YW,Lim YJ,Kim B,Lee SP

    更新日期：2020-04-24 00:00:00

  • Beliefs of UK Transplant Recipients about Living Kidney Donation and Transplantation: Findings from a Multicentre Questionnaire-Based Case-Control Study.

    abstract：:Differing beliefs about the acceptability of living-donor kidney transplants (LDKTs) have been proposed as explaining age, ethnic and socioeconomic disparities in their uptake. We investigated whether certain patient groups hold beliefs incompatible with LDKTs. This questionnaire-based case-control study was based at ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9010031

    authors： Bailey PK,Caskey FJ,MacNeill S,Tomson C,Dor FJMF,Ben-Shlomo Y

    更新日期：2019-12-21 00:00:00

  • Comparison of Three Nutritional Screening Tools with the New Glim Criteria for Malnutrition and Association with Sarcopenia in Hospitalized Older Patients.

    abstract：:The integrated assessment of nutritional status and presence of sarcopenia would help improve clinical outcomes of in-hospital aged patients. We compared three common nutritional screening tools with the new Global Leadership Initiative on Malnutrition (GLIM) diagnostic criteria among hospitalized older patients. To t...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9061898

    authors： Bellanti F,Lo Buglio A,Quiete S,Pellegrino G,Dobrakowski M,Kasperczyk A,Kasperczyk S,Vendemiale G

    更新日期：2020-06-17 00:00:00

  • The Effect of Preservation Temperature on Liver, Kidney, and Pancreas Tissue ATP in Animal and Preclinical Human Models.

    abstract：:The recent advances in machine perfusion (MP) technology involve settings ranging between hypothermic, subnormothermic, and normothermic temperatures. Tissue level adenosine triphosphate (ATP) is a long-established marker of viability and functionality and is universal for all organs. In the midst of a growing number ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm8091421

    authors： Bellini MI,Yiu J,Nozdrin M,Papalois V

    更新日期：2019-09-09 00:00:00

  • A Review of Multidisciplinary Interventions in Atopic Dermatitis.

    abstract：:Multidisciplinary interventions have been developed for patients with atopic dermatitis (AD) and their families, with the aim of improving outcomes such as disease control, adherence, and quality of life. We reviewed the content of different multidisciplinary approaches to intervention for AD and evidence for their im...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm4051156

    authors： Spielman SC,LeBovidge JS,Timmons KG,Schneider LC

    更新日期：2015-05-21 00:00:00

  • Cushing's Disease.

    abstract：:In patients with Cushing's disease (CD), prompt diagnosis and treatment are essential for favorable long-term outcomes, although this remains a challenging task. The differential diagnosis of CD is still difficult in some patients, even with an organized stepwise diagnostic approach. Moreover, despite the use of high-...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm8111951

    authors： Nishioka H,Yamada S

    更新日期：2019-11-12 00:00:00

  • Effects of Fructose or Glucose on Circulating ApoCIII and Triglyceride and Cholesterol Content of Lipoprotein Subfractions in Humans.

    abstract：:ApoCIII and triglyceride (TG)-rich lipoproteins (TRL), particularly, large TG-rich lipoproteins particles, have been described as important mediators of cardiovascular disease (CVD) risk. The effects of sustained consumption of dietary fructose compared with those of sustained glucose consumption on circulating apoCII...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8070913

    authors： Hieronimus B,Griffen SC,Keim NL,Bremer AA,Berglund L,Nakajima K,Havel PJ,Stanhope KL

    更新日期：2019-06-26 00:00:00

  • Impact of Women Obesity and Obesity Severity on Live Birth Rate after In Vitro Fertilization.

    abstract：:Access to in vitro fertilization (IVF) for obese women varies across centers, and the impact of obesity on IVF outcomes is widely discussed. We assessed the impact of obesity and its severity on live birth rate (LBR) after IVF. We included women treated for IVF in our center. Data were prospectively collected in the B...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9082414

    authors： Brunet C,Aouinti S,Huguet F,Macioce V,Ranisavljevic N,Gala A,Avignon A,Mura T,Sultan A

    更新日期：2020-07-28 00:00:00

  • Acute Kidney Injury and In-Hospital Mortality: A Retrospective Analysis of a Nationwide Administrative Database of Elderly Subjects in Italy.

    abstract：BACKGROUND:The aim of this study was to investigate the association between acute kidney injury (AKI) and in-hospital mortality (IHM) in a large nationwide cohort of elderly subjects in Italy. METHODS:We analyzed the hospitalization data of all patients aged ≥65 years, who were discharged with a diagnosis of AKI, whic...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8091371

    authors： Fabbian F,Savriè C,De Giorgi A,Cappadona R,Di Simone E,Boari B,Storari A,Gallerani M,Manfredini R

    更新日期：2019-09-02 00:00:00

  • Distinct Chemokine Dynamics in Early Postoperative Period after Open and Robotic Colorectal Surgery.

    abstract：:Stress response to robot-assisted colorectal surgery is largely unknown. Therefore, we conducted a prospective comparative nonrandomized study evaluating the perioperative dynamics of chemokines: IL-8/CXCL8, MCP-1/CCL2, MIP-1α/CCL3, MIP-1β/CCL4, RANTES/CCL5, and eotaxin-1/CCL11 in 61 colorectal cancer patients followi...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8060879

    authors： Krzystek-Korpacka M,Zawadzki M,Lewandowska P,Szufnarowski K,Bednarz-Misa I,Jacyna K,Witkiewicz W,Gamian A

    更新日期：2019-06-19 00:00:00