Abstract：
:Access to in vitro fertilization (IVF) for obese women varies across centers, and the impact of obesity on IVF outcomes is widely discussed. We assessed the impact of obesity and its severity on live birth rate (LBR) after IVF. We included women treated for IVF in our center. Data were prospectively collected in the BabySentryTM software. LBR per cycle and cumulative LBR including all attempts of the couple were calculated, considering transfer of both fresh and frozen embryos. Of 1588 included women (2379 controlled ovarian stimulations), 70.2%, 19.5%, 7.9%, and 2.4% were normal-weight, overweight, class I obesity, and class II/III obesity, respectively. For each cycle, LBR did not differ according to BMI category. Adjusted odds ratios (95% confidence intervals) for obtaining a live birth at the first cycle were 1.11 (0.78-1.58) for overweight, 1.17 (0.70-1.95) for class I obese, and 1.05 (0.48-2.31) for class II/III obese women, as compared with normal-weight women. Similarly, no significant associations were found at cycles 2, 3, and 4. Cumulative LBR increased with the number of cycles, independently of the BMI class (p log-rank = 0.91). After adjustment, obesity status did not impact significantly the miscarriage rate, regardless of the cycle. In conclusion, neither women obesity nor its severity impacted the cumulative LBR after IVF.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Brunet C,Aouinti S,Huguet F,Macioce V,Ranisavljevic N,Gala A,Avignon A,Mura T,Sultan Adoi
10.3390/jcm9082414subject
Has Abstractpub_date
2020-07-28 00:00:00issue
8issn
2077-0383pii
jcm9082414journal_volume
9pub_type
杂志文章abstract：:One in every four deaths is due to cancer in Europe. In view of its increasing incidence, cancer became the leading cause of death and disease burden in Denmark, France, the Netherlands, and the UK. Without essential improvements in cancer prevention, an additional 775,000 cases of annual incidence have been prognosed...
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更新日期：2014-10-29 00:00:00
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更新日期：2014-03-11 00:00:00
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pub_type： 杂志文章
doi：10.3390/jcm8081102
更新日期：2019-07-25 00:00:00
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pub_type： 杂志文章
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更新日期：2018-11-06 00:00:00
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更新日期：2021-01-14 00:00:00
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pub_type： 杂志文章
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更新日期：2020-06-03 00:00:00
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pub_type： 杂志文章,评审
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pub_type： 社论
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更新日期：2015-08-14 00:00:00
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更新日期：2020-07-09 00:00:00
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