解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Surface-enhanced Raman scattering (SERS) is highly sensitive and label-free analytical technique based on Raman spectroscopy aided by field-multiplying plasmonic nanostructures. We report the use of SERS measurements of patient urine in conjunction with biostatistical algorithms to assess the treatment response of pro...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000275
更新日期:2021-01-01 00:00:00
abstract::Articular cartilage posesses unique material properties due to a complex depth-dependent composition of sub-components. Raman spectroscopy has proven valuable in quantifying this composition through cartilage cross-sections. However, cross-sectioning requires tissue destruction and is not practical in situ. In this wo...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000289
更新日期:2021-01-01 00:00:00
abstract::Optical coherence tomography (OCT) imaging shows a significant potential in clinical routines due to its noninvasive property. However, the quality of OCT images is generally limited by inherent speckle noise of OCT imaging and low sampling rate. To obtain high signal-to-noise ratio (SNR) and high-resolution (HR) OCT ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000282
更新日期:2021-01-01 00:00:00
abstract::In photoacoustic tomography (PAT), a tunable laser typically illuminates the tissue at multiple wavelengths, and the received photoacoustic waves are used to form functional images of relative total haemoglobin (rHbT) and blood oxygenation saturation (%sO2 ). Due to measurement errors, the estimation of these paramete...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000368
更新日期:2020-12-30 00:00:00
abstract::Since stimulated emission depletion (STED) nanoscopy was invented in 1994, this technique has been widely used in the fields of biomedicine and materials science. According to the imaging principle of STED technology, increasing the power of the depletion laser within a certain threshold can improve the resolution. Ho...
journal_title:Journal of biophotonics
pub_type: 信件
doi:10.1002/jbio.202000402
更新日期:2020-12-13 00:00:00
abstract::Infrared spectra obtained from cell or tissue specimen have commonly been observed to involve a significant degree of scattering effects, often Mie scattering, which probably overshadows biochemically relevant spectral information by a nonlinear, nonadditive spectral component in Fourier transform infrared (FTIR) spec...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000385
更新日期:2020-12-08 00:00:00
abstract::The class of PEGylated emulsifiers finds broad application in the pharmaceutical and cosmetic industry. We target on one of the categories of polyethylene glycol (PEG) alkyl ethers with different lipophilic and hydrophilic chain length and aim to examine their effects on the skin comprehensively. In this study, we emp...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000286
更新日期:2020-12-01 00:00:00
abstract::This study presents numerical simulations of UVC light propagation through seven different filtered face respirators (FFR) to determine their suitability for Ultraviolet germicidal inactivation (UVGI). UV propagation was modeled using the FullMonte program for two external light illuminations. The optical properties o...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000232
更新日期:2020-12-01 00:00:00
abstract::Endoscopy has been widely used in biomedical imaging and integrated with various optical and acoustic imaging modalities. Photoacoustic imaging (PAI), one of the fastest growing biomedical imaging modalities, is a noninvasive and nonionizing method that owns rich optical contrast, deep acoustic penetration depth, mult...
journal_title:Journal of biophotonics
pub_type: 杂志文章,评审
doi:10.1002/jbio.202000217
更新日期:2020-12-01 00:00:00
abstract::Myelin is a key component of the peripheral nervous system, whose structure anomaly in the digital skin is implicated in neuropathy. Here we demonstrate an in vivo labeling and imaging technique, capable of visualizing myelin sheaths deep in the mouse digital skin. Through material characterization, we verify that 3-p...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000321
更新日期:2020-12-01 00:00:00
abstract::Whole slide imaging (WSI) has moved digital pathology closer to diagnostic practice in recent years. Due to the inherent tissue topography variability, accurate autofocusing remains a critical challenge for WSI and automated microscopy systems. The traditional focus map surveying method is limited in its ability to ac...
journal_title:Journal of biophotonics
pub_type: 杂志文章,评审
doi:10.1002/jbio.202000227
更新日期:2020-12-01 00:00:00
abstract::Pancreatic islet isolation from donor pancreases is an essential step for the transplantation of insulin-secreting β-cells as a therapy to treat type 1 diabetes mellitus. This process however damages islet basement membranes, which can lead to islet dysfunction or death. Posttransplantation, islets are further stresse...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000375
更新日期:2020-12-01 00:00:00
abstract::The possibilities of using Mueller matrix (MM) imaging polarimetry to assess meat quality have not yet been sufficiently explored. In the current study, the fresh porcine muscles are imaged at room temperature with a wide-field MM imaging polarimeter over 26 hours to visualize dynamics of tissue optical properties thr...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000376
更新日期:2020-11-21 00:00:00
abstract::The aim of this work was to assess the antimicrobial efficacy on Pseudomonas aeruginosa of nanomicelles loaded with curcumin (CUR) alone and activated by blue laser light in an antimicrobial photodynamic therapy (APDT) approach. First, free CUR in liquid suspension and loaded in three amphiphilic nanomicelles (CUR-DAP...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000350
更新日期:2020-11-05 00:00:00
abstract::Solar radiation exposure is recognised to be a significant contributor to the development of skin cancer. Monitoring the simultaneous and consecutive mechanisms of interaction could provide a greater understanding of the process of photocarcinogenesis. This work presents an analysis of the biochemical and morphologica...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000337
更新日期:2020-10-24 00:00:00
abstract::The sun protection factor (SPF) values are currently determined using an invasive procedure, in which the volunteers are irradiated with ultraviolet (UV) light. Non-invasive approaches based on hybrid diffuse reflectance spectroscopy (HDRS) have shown a good correlation with conventional SPF testing. Here, we present ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000348
更新日期:2020-10-06 00:00:00
abstract::Photodynamic inactivation (PDI) is a promising alternative for combating infections caused by antimicrobial resistant bacteria. Pneumonias are among the most worrisome infections because of their high-mortality rate. Previous studies have demonstrated the feasibility of using PDI with extracorporeal light to treat pne...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000176
更新日期:2020-10-01 00:00:00
abstract::The content of dermal beta-carotene can be a good indicator showing the body health. Because, it is involved in production of vitamin A maintaining healthy skin and mucous membranes. Also, it reduces the risk of cardiovascular diseases and its antioxidant capacity prevents the formation of cancerous cells. In this wor...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000124
更新日期:2020-09-01 00:00:00
abstract::The purpose of this study was to evaluate early vascular and tomographic changes in the retina of diabetic patients using artificial intelligence (AI). The study included 74 age-matched normal eyes, 171 diabetic eyes without retinopathy (DWR) eyes and 69 mild non-proliferative diabetic retinopathy (NPDR) eyes. All pat...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000107
更新日期:2020-09-01 00:00:00
abstract::Despite an ever increasing demand for reliable and cheap methods in the detection and quantification of microbes, surprisingly few investigations have explored or utilized the luminescence of rare earths in the microbial context, neither in conventional, that is, plating and microscopic imaging techniques, nor in adva...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000068
更新日期:2020-09-01 00:00:00
abstract::Current elastography techniques are limited in application to accurately assess spatially resolved corneal elasticity in vivo for human eyes. The air-puff optical coherence elastography (OCE) with an eye motion artifacts correction algorithm is developed to distinguish the in vivo cornea vibration from the eye motion ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000104
更新日期:2020-08-01 00:00:00
abstract::We present a pseudo-real-time retinal layer segmentation for high-resolution Sensorless Adaptive Optics-Optical Coherence Tomography (SAO-OCT). Our pseudo-real-time segmentation method is based on Dijkstra's algorithm that uses the intensity of pixels and the vertical gradient of the image to find the minimum cost in ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.202000042
更新日期:2020-08-01 00:00:00
abstract::Limb perfusion monitoring is critical for diabetes mellitus (DM) patients as they are vulnerable to vascular complications due to prolonged hyperglycemia. However, current clinical approaches are ineffective in vascular imaging and in assessing vascular function in lower limbs. In this work, a concave ultrasound trans...
journal_title:Journal of biophotonics
pub_type: 信件
doi:10.1002/jbio.202000011
更新日期:2020-08-01 00:00:00
abstract::Perfusion and oxygenation are critical parameters of muscle metabolism in health and disease. They have been both the target of many studies, in particular using near-infrared spectroscopy (NIRS). However, difficulties with quantifying NIRS signals have limited a wide dissemination of the method to the clinics. Our ai...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201960169
更新日期:2020-06-01 00:00:00
abstract::Stereotaxic instruments are increasingly used in research animals for the study of disease, but typically require restraints and anesthetic procedures. A stereotaxic head mount that enables imaging of the anterior chamber of the eye in alert and freely mobile mice is presented in this study. The head mount is fitted b...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201960188
更新日期:2020-05-01 00:00:00
abstract::Cutaneous squamous cell carcinoma (cSCC) is a common skin cancer with metastatic potential. To reduce reoperations due to nonradical excision, there is a need to develop a technique for identification of tumor margins preoperatively. Photoacoustic (PA) imaging is a novel imaging technology that combines the strengths ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201960212
更新日期:2020-05-01 00:00:00
abstract::In preclinical researches, bioluminescence tomography (BLT) has widely been used for tumor imaging and monitoring, imaged-guided tumor therapy, and so forth. For these biological applications, both tumor spatial location and morphology analysis are the leading problems needed to be taken into account. However, most ex...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201960218
更新日期:2020-04-01 00:00:00
abstract::The above article from the Journal of Biophotonics, published online on 9 January 2018 in Wiley Online Library as Early View (https://onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201700354), and in Volume 11, e201700354, has been retracted by agreement between the authors (Hong Zhong, Lin Lu, Yuanhao Wang, Hongxing Ya...
journal_title:Journal of biophotonics
pub_type: 杂志文章,撤回出版物
doi:10.1002/jbio.201890133
更新日期:2020-04-01 00:00:00
abstract::In the current clinical care practice, Gleason grading system is one of the most powerful prognostic predictors for prostate cancer (PCa). The grading system is based on the architectural pattern of cancerous epithelium in histological images. However, the standard procedure of histological examination often involves ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900203
更新日期:2020-02-01 00:00:00
abstract::For the screening purposes urine is an especially attractive biofluid, since it offers easy and noninvasive sample collection and provides a snapshot of the whole metabolic status of the organism, which may change under different pathological conditions. Raman spectroscopy (RS) has the potential to monitor these chang...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900143
更新日期:2020-01-01 00:00:00
abstract::Intravascular optical coherence tomography (IV-OCT) is a light-based imaging modality with high resolution, which employs near-infrared light to provide tomographic intracoronary images. Morbidity caused by coronary heart disease is a substantial cause of acute coronary syndrome and sudden cardiac death. The most comm...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900112
更新日期:2020-01-01 00:00:00
abstract::Previous studies for melanin visualization in the retinal pigment epithelium (RPE) have exploited either its absorption properties (using photoacoustic tomography or photothermal optical coherence tomography [OCT]) or its depolarization properties (using polarization sensitive OCT). However, these methods are only sui...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900153
更新日期:2019-12-01 00:00:00
abstract::Total internal reflection fluorescence excitation (TIRF) microscopy allows the selective observation of fluorescent molecules in immediate proximity to an interface between different refractive indices. Objective-type or prism-less TIRF excitation is typically achieved with laser light sources. We here propose a simpl...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900033
更新日期:2019-11-01 00:00:00
abstract::Retinoblastoma (RB) is a rare form of cancer of the retina most prevalent in young children. We successfully show that laser-induced cell disruption, mediated by gold plasmonic nanoparticle (NP), is a potential and efficient therapy to kill the cancerous cells. The proof of concept is demonstrated in vitro on cultured...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900193
更新日期:2019-11-01 00:00:00
abstract::The fluorescence lifetime of nicotinamide adenine dinucleotide (NADH) is commonly used in conjunction with the phasor approach as a molecular biomarker to provide information on cellular metabolism of autofluorescence imaging of cells and tissue. However, in the phasor approach, the bound and free lifetime defining th...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900156
更新日期:2019-11-01 00:00:00
abstract::Methods of nonlinear optics provide a vast arsenal of tools for label-free brain imaging, offering a unique combination of chemical specificity, the ability to detect fine morphological features, and an unprecedentedly high, subdiffraction spatial resolution. While these techniques provide a rapidly growing platform f...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201800432
更新日期:2019-11-01 00:00:00
abstract::Hyperspectral imaging is a promising technique for resection margin assessment during cancer surgery. Thereby, only a specific amount of the tissue below the resection surface, the clinically defined margin width, should be assessed. Since the imaging depth of hyperspectral imaging varies with wavelength and tissue co...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900086
更新日期:2019-11-01 00:00:00
abstract::The dynamic properties of subcellular organism are important biomarkers of the health. Imaging subcellular level dynamics provides effective solutions for evaluating cell metabolism and testing the responses of cells to pathogens and drugs in pharmaceutical engineering. In this paper, we demonstrate an innovative appr...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900076
更新日期:2019-10-01 00:00:00
abstract::The aim of this study was to evaluate whether OCT topography of the Bowman's layer and artificial intelligence (AI) can result in better diagnosis of forme fruste (FFKC) and clinical keratoconus (KC). Normal (n = 221), FFKC (n = 72) and KC (n = 116) corneas were included. Some of the FFKC and KC patients had the fello...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900126
更新日期:2019-10-01 00:00:00
abstract::Laser therapy, also known as Photobiomodulation (PBM) is indicated to reduce pain associated with different pathologies and applied using protocols that vary in wavelength, irradiance and fluence. Its mechanisms of action are still unclear and possibly able to directly impact on pain transmission, reducing nociceptor ...
journal_title:Journal of biophotonics
pub_type: 杂志文章
doi:10.1002/jbio.201900043
更新日期:2019-10-01 00:00:00