Abstract:
:Current elastography techniques are limited in application to accurately assess spatially resolved corneal elasticity in vivo for human eyes. The air-puff optical coherence elastography (OCE) with an eye motion artifacts correction algorithm is developed to distinguish the in vivo cornea vibration from the eye motion and visualize the Lamb wave propagation clearly in healthy subjects. Based on the Lamb wave model, the phase velocity dispersion curve in the high-frequency is calculated to obtain spatially resolved corneal elasticity accurately with high repeatability. It is found that the corneal elasticity has regional variations and is correlated with intraocular pressure, which suggests that the method has the potential to provide noninvasive measurement of spatially resolved corneal elasticity in clinical practice.
journal_name
J Biophotonicsjournal_title
Journal of biophotonicsauthors
Jin Z,Chen S,Dai Y,Bao C,Ye S,Zhou Y,Wang Y,Huang S,Wang Y,Shen M,Zhu D,Lu Fdoi
10.1002/jbio.202000104subject
Has Abstractpub_date
2020-08-01 00:00:00pages
e202000104issue
8eissn
1864-063Xissn
1864-0648journal_volume
13pub_type
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