Topographic prominence as a method for cluster identification in single-molecule localisation data.

abstract：:Uncoated and poly(styrene sulphonate) (PSS)-coated gold nanorods were taken up by NG108-15 neuronal cells. Exposure to 780 nm laser light at the plasmon resonance wavelength of the gold nanorods was found to induce intracellular Ca(2+) transients. The higher Ca(2+) peaks were observed at lower laser doses, with the hi...

journal_title：Journal of biophotonics

authors： Paviolo C,Haycock JW,Cadusch PJ,McArthur SL,Stoddart PR

更新日期：2014-10-01 00:00:00

abstract：:A conceptually new type of corneal inlays for a customized treatment of presbyopia is presented. The diffractive inlay consists on a small aperture disc having an array of micro-holes distributed inside the open zones of a Fresnel zone plate. In this way, the central hole of the disc lets pass the zero order diffracti...

journal_title：Journal of biophotonics

authors： Furlan WD,García-Delpech S,Udaondo P,Remón L,Ferrando V,Monsoriu JA

更新日期：2017-09-01 00:00:00

abstract：:5-aminolevulinic acid (ALA) and its methylated ester (MAL) are the most common topical agents used in photodynamic therapy (PDT) as precursors of the photosensitizer protoporphyrin IX (PpIX). The induction of newly PpIX depends on incubation time of each photosensitizer in the tissue and the presence of high intralesi...

journal_title：Journal of biophotonics

authors： Lima CA,Goulart VP,Bechara EJ,Correa L,Zezell DM

更新日期：2016-12-01 00:00:00

abstract：:Tumor metastasis to lymph nodes is an important contributory factor for cancer-related deaths despite recent developments in cancer therapy. In this study, we demonstrate that tumor in the proper axillary lymph node (PALN) of the mouse can be treated by the application of external laser light to trigger the unloading ...

journal_title：Journal of biophotonics

authors： Matsuki D,Adewale O,Horie S,Okajima J,Komiya A,Oluwafemi O,Maruyama S,Mori S,Kodama T

更新日期：2017-12-01 00:00:00

abstract：:Current elastography techniques are limited in application to accurately assess spatially resolved corneal elasticity in vivo for human eyes. The air-puff optical coherence elastography (OCE) with an eye motion artifacts correction algorithm is developed to distinguish the in vivo cornea vibration from the eye motion ...

journal_title：Journal of biophotonics

authors： Jin Z,Chen S,Dai Y,Bao C,Ye S,Zhou Y,Wang Y,Huang S,Wang Y,Shen M,Zhu D,Lu F

更新日期：2020-08-01 00:00:00

abstract：:Retinoblastoma (RB) is a rare form of cancer of the retina most prevalent in young children. We successfully show that laser-induced cell disruption, mediated by gold plasmonic nanoparticle (NP), is a potential and efficient therapy to kill the cancerous cells. The proof of concept is demonstrated in vitro on cultured...

journal_title：Journal of biophotonics

authors： Darviot C,Hardy P,Meunier M

更新日期：2019-11-01 00:00:00

abstract：:Ectasia after refractive surgery represents a major concern among refractive surgeons. Corneal abnormalities and preexisting corneal ectasia are the most important risk factors. Corneal topography and central corneal thickness are the factors traditionally screening for in refractive surgery candidates. Study of the a...

journal_title：Journal of biophotonics

authors： Luz A,Lopes B,Salomão M,Ambrósio R

更新日期：2016-05-01 00:00:00

abstract：:Zinc metallized Phthalocyanine (ZnPcSmix ), a potent photosensitizer, is conjugated to gold dendrimer encapsulated nanoparticles (AuDENPs) in order to improve the efficacy of photodynamic therapy (PDT) using MCF-7 breast cancer cells and WS1 fibroblast cells as a control. Both ZnPcSmix and AuDENPs are mixed in a nitro...

journal_title：Journal of biophotonics

authors： Mfouo-Tynga I,Houreld NN,Abrahamse H

更新日期：2018-02-01 00:00:00

abstract：:For a precise manipulation of particles and cells with laser light as well as for the understanding and the control of the underlying processes it is important to visualize and quantify the response of the specimens. Thus, we investigated if digital holographic microscopy (DHM) can be used in combination with microflu...

journal_title：Journal of biophotonics

authors： Kemper B,Langehanenberg P,Höink A,von Bally G,Wottowah F,Schinkinger S,Guck J,Käs J,Bredebusch I,Schnekenburger J,Schütze K

更新日期：2010-07-01 00:00:00

abstract：:The research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using 'Laser Induced Breakdown Spectroscopy' (LIBS) on the plasma plume created during laser tissue ablation. The background of this study is to establish a real time feedback ...

journal_title：Journal of biophotonics

authors： Kanawade R,Mahari F,Klämpfl F,Rohde M,Knipfer C,Tangermann-Gerk K,Adler W,Schmidt M,Stelzle F

更新日期：2015-01-01 00:00:00

abstract：:Articular cartilage posesses unique material properties due to a complex depth-dependent composition of sub-components. Raman spectroscopy has proven valuable in quantifying this composition through cartilage cross-sections. However, cross-sectioning requires tissue destruction and is not practical in situ. In this wo...

journal_title：Journal of biophotonics

authors： Mason D,Murugkar S,Speirs AD

更新日期：2021-01-01 00:00:00

abstract：:The possibilities of using Mueller matrix (MM) imaging polarimetry to assess meat quality have not yet been sufficiently explored. In the current study, the fresh porcine muscles are imaged at room temperature with a wide-field MM imaging polarimeter over 26 hours to visualize dynamics of tissue optical properties thr...

journal_title：Journal of biophotonics

authors： Peyvasteh M,Popov A,Bykov A,Pierangelo A,Novikova T,Meglinski I

更新日期：2020-11-21 00:00:00

abstract：:Since stimulated emission depletion (STED) nanoscopy was invented in 1994, this technique has been widely used in the fields of biomedicine and materials science. According to the imaging principle of STED technology, increasing the power of the depletion laser within a certain threshold can improve the resolution. Ho...

journal_title：Journal of biophotonics

authors： Wang J,Wang L,Zhang J,Yang Z,Yan W,Qu J

更新日期：2020-12-13 00:00:00

abstract：:In vivo visualization of the human lymphatic system is limited by the mode of delivery of tracing agents, depth of field and size of the area examined, and specificity of the cell markers used to distinguish lymphatic endothelium from the blood vessels and the surrounding tissues. These limitations are particularly pr...

journal_title：Journal of biophotonics

authors： Lokmic Z

更新日期：2018-08-01 00:00:00

abstract：:Optical sectioning endoscopy such as confocal endoscopy offers capabilities to obtain three-dimensional (3D) information from various biological samples by discriminating between the desired in-focus signals and out-of-focus background. However, in general confocal images are formed through point-by-point scanning and...

journal_title：Journal of biophotonics

authors： Lin WT,Lin CY,Singh VR,Luo Y

更新日期：2018-11-01 00:00:00

abstract：:A new optical scattering contrast-agent based on polymer-nanoparticle encapsulated silver nanoplates (PESNs) is presented. Silver nanoplates were chosen due to the flexibility of tuning their plasmon frequencies. The polymer coating preserves their physical and optical properties and confers other advantages such as c...

journal_title：Journal of biophotonics

authors： Ray A,Kopelman R,Chon B,Briggman K,Hwang J

更新日期：2016-07-01 00:00:00

abstract：:The investigation of lung dynamics on alveolar scale is crucial for the understanding and treatment of lung diseases, such as acute lung injury and ventilator induced lung injury, and to promote the development of protective ventilation strategies. One approach to this is the establishment of numerical simulations of ...

journal_title：Journal of biophotonics

authors： Kirsten L,Gaertner M,Schnabel C,Meissner S,Koch E

更新日期：2013-02-01 00:00:00

abstract：:We develop a confocal system equipped with optimal elliptical apertures to improve axial point spread function and signal-to-background ratio (SBR) for different detector sizes. By adjusting the parameters of the elliptical apertures, the axial half width at half-maximum can be reduced to 4.986 (described in optical c...

journal_title：Journal of biophotonics

authors： Tang H,Wu C,Gong W,Zheng Y,Zhu X,Wang J,Si K

更新日期：2018-05-01 00:00:00

abstract：:The aim of the present study is to optimize parameters for inhibiting neuronal activity safely and investigating thermal inhibition of rat cortex neural networks in vitro by continuous infrared (IR) laser. Rat cortex neurons were cultured on multi-electrode arrays until neural networks were formed with spontaneous neu...

journal_title：Journal of biophotonics

authors： Xia Q,Nyberg T

更新日期：2019-07-01 00:00:00

abstract：:We present a pseudo-real-time retinal layer segmentation for high-resolution Sensorless Adaptive Optics-Optical Coherence Tomography (SAO-OCT). Our pseudo-real-time segmentation method is based on Dijkstra's algorithm that uses the intensity of pixels and the vertical gradient of the image to find the minimum cost in ...

journal_title：Journal of biophotonics

authors： Janpongsri W,Huang J,Ng R,Wahl DJ,Sarunic MV,Jian Y

更新日期：2020-08-01 00:00:00

abstract：:We introduce a unique method for laser-propelling individual cells over distances of 10s of cm through stationary liquid in a microfluidic channel. This is achieved by using liquid-filled hollow-core photonic crystal fiber (HC-PCF). HC-PCF provides low-loss light guidance in a well-defined single mode, resulting in hi...

journal_title：Journal of biophotonics

authors： Unterkofler S,Garbos MK,Euser TG,St J Russell P

更新日期：2013-09-01 00:00:00

abstract：:Dynamic follow-up of exogenous molecules permeation through the skin is one among many competing applications for confocal Raman microspectroscopy. Previous studies showed the feasibility of tracking actives through the skin; the next step should be recording in vivo kinetics. Thus, we conducted a study to evaluate th...

journal_title：Journal of biophotonics

authors： Tfaili S,Josse G,Angiboust JF,Manfait M,Piot O

更新日期：2014-09-01 00:00:00

abstract：:We have investigated the ability of dual-frequency Coherent Antistokes Raman Scattering (D-CARS) micro-spectroscopy, based on femtosecond pulses (100 fs or 5 fs) spectrally focussed by glass dispersion, to distinguish the chemical composition of micron-sized lipid droplets consisting of different triglycerides types (...

journal_title：Journal of biophotonics

authors： Di Napoli C,Masia F,Pope I,Otto C,Langbein W,Borri P

更新日期：2014-01-01 00:00:00

abstract：:We describe a novel, minimally invasive laser technology for skin rejuvenation by creating isolated microscopic lesions within tissue below the epidermis using laser induced optical breakdown. Using an in-house built prototype device, tightly focused near-infrared laser pulses are used to create optical breakdown in t...

journal_title：Journal of biophotonics

authors： Habbema L,Verhagen R,Van Hal R,Liu Y,Varghese B

更新日期：2012-02-01 00:00:00

abstract：:We report the use of ultrasound modulated optical tomography (UOT) with heterodyne parallel detection to locally sense and image blood flow deep inside a highly scattering medium. We demonstrate that the UOT signal is sensitive to the speed of the blood flow in the ultrasound focus and present an analytical model that...

journal_title：Journal of biophotonics

authors： Hussain A,Steenbergen W,Vellekoop IM

更新日期：2018-01-01 00:00:00

abstract：:Three-dimensional reconstruction of tissue structures is essential for biomedical research. The development of light microscopes and various fluorescent labeling techniques provides powerful tools for this motivation. However, optical imaging depth suffers from strong light scattering due to inherent heterogeneity of ...

journal_title：Journal of biophotonics

authors： Yu T,Qi Y,Gong H,Luo Q,Zhu D

更新日期：2018-02-01 00:00:00

abstract：:The effect of cetyl-trimethylammonium bromide (CTAB) on enhancing the fluorescence resonance energy transfer (FRET) between two dye-conjugated DNA strands was studied using fluorescence emission spectroscopy and dynamic light scattering (DLS). For hybridized DNA where one strand is conjugated with a TAMRA donor and th...

journal_title：Journal of biophotonics

authors： Oh T,Takahashi T,Kim S,Heller MJ

更新日期：2016-01-01 00:00:00

abstract：:Low-level laser therapy (LLLT) is known to enhance mitochondrial electron transfer and ATP production; thus, this study asked whether LLLT could stimulate the oxidative burst in human neutrophils (PMN) and improve their ability to kill microorganisms. Blood from healthy human subjects was collected and PMN were isolat...

journal_title：Journal of biophotonics

authors： Cerdeira CD,Lima Brigagão MR,Carli ML,de Souza Ferreira C,de Oliveira Isac Moraes G,Hadad H,Costa Hanemann JA,Hamblin MR,Sperandio FF

更新日期：2016-12-01 00:00:00

abstract：:The class of PEGylated emulsifiers finds broad application in the pharmaceutical and cosmetic industry. We target on one of the categories of polyethylene glycol (PEG) alkyl ethers with different lipophilic and hydrophilic chain length and aim to examine their effects on the skin comprehensively. In this study, we emp...

journal_title：Journal of biophotonics

authors： Liu Y,Lunter DJ

更新日期：2020-12-01 00:00:00

abstract：:The purpose of this study was to evaluate the tomographic features of postrefractive surgery eyes. This was a retrospective evaluation of clinical data. Three patients with post-LASIK (laser-assisted in situ keratomileusis) and two patients with post-SMILE (small incision lenticule extraction) ectasia were imaged with...

journal_title：Journal of biophotonics

authors： Khamar P,Dalal R,Chandapura R,Francis M,Shetty R,Nelson EJR,Nuijts RMMA,Sinha Roy A

更新日期：2019-02-01 00:00:00