Abstract:
:For a precise manipulation of particles and cells with laser light as well as for the understanding and the control of the underlying processes it is important to visualize and quantify the response of the specimens. Thus, we investigated if digital holographic microscopy (DHM) can be used in combination with microfluidics to observe optically trapped living cells in a minimally invasive fashion during laser micromanipulation. The obtained results demonstrate that DHM multi-focus phase contrast provides label-free quantitative monitoring of optical manipulation with a temporal resolution of a few milliseconds.
journal_name
J Biophotonicsjournal_title
Journal of biophotonicsauthors
Kemper B,Langehanenberg P,Höink A,von Bally G,Wottowah F,Schinkinger S,Guck J,Käs J,Bredebusch I,Schnekenburger J,Schütze Kdoi
10.1002/jbio.201000035subject
Has Abstractpub_date
2010-07-01 00:00:00pages
425-31issue
7eissn
1864-063Xissn
1864-0648journal_volume
3pub_type
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