Optimization for imaging through scattering media for confocal microscopes with divided elliptical apertures.

Abstract:

:We develop a confocal system equipped with optimal elliptical apertures to improve axial point spread function and signal-to-background ratio (SBR) for different detector sizes. By adjusting the parameters of the elliptical apertures, the axial half width at half-maximum can be reduced to 4.986 (described in optical coordinates) and SBR can be improved to 0.176. We evaluate this system with the 1951 USAF resolution test chart and the primary cultured neuron from SD rat stained by Map-2, and observe better imaging performance, which indicates the potential applications in biological science.

journal_name

J Biophotonics

journal_title

Journal of biophotonics

authors

Tang H,Wu C,Gong W,Zheng Y,Zhu X,Wang J,Si K

doi

10.1002/jbio.201700293

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

e201700293

issue

5

eissn

1864-063X

issn

1864-0648

journal_volume

11

pub_type

杂志文章
  • Artifact-free objective-type multicolor total internal reflection fluorescence microscopy with light-emitting diode light sources-Part I.

    abstract::Total internal reflection fluorescence excitation (TIRF) microscopy allows the selective observation of fluorescent molecules in immediate proximity to an interface between different refractive indices. Objective-type or prism-less TIRF excitation is typically achieved with laser light sources. We here propose a simpl...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201900033

    authors: Kogel A,Kalwa H,Urban N,Schaefer M

    更新日期:2019-11-01 00:00:00

  • A helpful technology--the luminescence detection of singlet oxygen to investigate photodynamic inactivation of bacteria (PDIB).

    abstract::Photodynamic inactivation of bacteria (PDIB) is considered a new approach for the struggle against multiresistant bacteria. To achieve a sufficient level of bacteria killing, the photosensitizer must attach to and/or penetrate the bacteria and generate a sufficiently high amount of singlet oxygen. To optimize PDIB, th...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.200900106

    authors: Regensburger J,Maisch T,Felgenträger A,Santarelli F,Bäumler W

    更新日期:2010-06-01 00:00:00

  • High-resolution tomographic diffractive microscopy of biological samples.

    abstract::The authors have developed a tomographic diffractive microscope that combines microholography with illumination from an angular synthetic aperture. It images specimens relative to their complex index of refraction distribution (index and absorption) and permits imaging of unlabelled specimens, with high lateral resolu...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.200900094

    authors: Simon B,Debailleul M,Beghin A,Tourneur Y,Haeberlé O

    更新日期:2010-07-01 00:00:00

  • Retraction: Zhong H, Lu L, Wang Y, Yang H. Single layer molybdenum disulfide as an optical nanoprobe for 2 photon luminescence and second harmonic generation cell imaging. J. Biophotonics. 2018;11:e201700354.

    abstract::The above article from the Journal of Biophotonics, published online on 9 January 2018 in Wiley Online Library as Early View (https://onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201700354), and in Volume 11, e201700354, has been retracted by agreement between the authors (Hong Zhong, Lin Lu, Yuanhao Wang, Hongxing Ya...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章,撤回出版物

    doi:10.1002/jbio.201890133

    authors:

    更新日期:2020-04-01 00:00:00

  • Biocompatible astaxanthin as novel contrast agent for biomedical imaging.

    abstract::Photoacoustic imaging (PAI) is a hybrid imaging modality with high resolution and sensitivity that can be beneficial for cancer staging. Due to insufficient endogenous photoacoustic (PA) contrast, the development of exogenous agents is critical in targeting cancerous tumors. The current study demonstrates the feasibil...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201600159

    authors: Nguyen VP,Park S,Oh J,Wook Kang H

    更新日期:2017-08-01 00:00:00

  • Nonlinear-optical stain-free stereoimaging of astrocytes and gliovascular interfaces.

    abstract::Methods of nonlinear optics provide a vast arsenal of tools for label-free brain imaging, offering a unique combination of chemical specificity, the ability to detect fine morphological features, and an unprecedentedly high, subdiffraction spatial resolution. While these techniques provide a rapidly growing platform f...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800432

    authors: Lanin AA,Pochechuev MS,Chebotarev AS,Kelmanson IV,Belousov VV,Zheltikov AM

    更新日期:2019-11-01 00:00:00

  • N2NSR-OCT: Simultaneous denoising and super-resolution in optical coherence tomography images using semisupervised deep learning.

    abstract::Optical coherence tomography (OCT) imaging shows a significant potential in clinical routines due to its noninvasive property. However, the quality of OCT images is generally limited by inherent speckle noise of OCT imaging and low sampling rate. To obtain high signal-to-noise ratio (SNR) and high-resolution (HR) OCT ...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.202000282

    authors: Qiu B,You Y,Huang Z,Meng X,Jiang Z,Zhou C,Liu G,Yang K,Ren Q,Lu Y

    更新日期:2021-01-01 00:00:00

  • Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study.

    abstract::The capabilities of cross-polarization optical coherence tomography (CP OCT) for early bladder-cancer detection are assessed in statistical study and compared with the traditional OCT. Unlike the traditional OCT that demonstrates images only in copolarization, CP OCT acquires images in cross-polarization and copolariz...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201000088

    authors: Gladkova N,Streltsova O,Zagaynova E,Kiseleva E,Gelikonov V,Gelikonov G,Karabut M,Yunusova K,Evdokimova O

    更新日期:2011-08-01 00:00:00

  • Low-power laser irradiation in salivary glands reduces glycemia in streptozotocin-induced diabetic female rats.

    abstract::Low-power laser irradiation (LPLI) has been extensively employed to modulate inflammation in vitro and in vivo. Previous reports from our group indicated that LPLI might regulate glycemia in diabetic animals. Diabetes results in chronic hyperglycemia and therefore chronic inflammation by upregulation of inflammatory m...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201600175

    authors: Fukuoka CY,Torres Schröter G,Nicolau J,Simões A

    更新日期:2016-12-01 00:00:00

  • Validation of delay-multiply-and-standard-deviation weighting factor for improved photoacoustic imaging of sentinel lymph node.

    abstract::Delay-and-sum (DAS) is one of the most common algorithms used to construct the photoacoustic images due to its low complexity. However, it results in images with high sidelobes and low resolution. Delay-and-standard-deviation (DASD) weighting factor can improve the contrast of the images compared to DAS. However, it s...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800292

    authors: Paridar R,Mozaffarzadeh M,Periyasamy V,Basij M,Mehrmohammadi M,Pramanik M,Orooji M

    更新日期:2019-06-01 00:00:00

  • Towards Raman spectroscopy of urine as screening tool.

    abstract::For the screening purposes urine is an especially attractive biofluid, since it offers easy and noninvasive sample collection and provides a snapshot of the whole metabolic status of the organism, which may change under different pathological conditions. Raman spectroscopy (RS) has the potential to monitor these chang...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201900143

    authors: Žukovskaja O,Ryabchykov O,Straßburger M,Heinekamp T,Brakhage AA,Hennings CJ,Hübner CA,Wegmann M,Cialla-May D,Bocklitz TW,Weber K,Popp J

    更新日期:2020-01-01 00:00:00

  • Bowman's topography for improved detection of early ectasia.

    abstract::The aim of this study was to evaluate whether OCT topography of the Bowman's layer and artificial intelligence (AI) can result in better diagnosis of forme fruste (FFKC) and clinical keratoconus (KC). Normal (n = 221), FFKC (n = 72) and KC (n = 116) corneas were included. Some of the FFKC and KC patients had the fello...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201900126

    authors: Chandapura R,Salomão MQ,Ambrósio R Jr,Swarup R,Shetty R,Sinha Roy A

    更新日期:2019-10-01 00:00:00

  • Cell lineage responses to photobiomodulation therapy.

    abstract::Photobiomodulation (PBM) therapy has been noted to promote cell proliferation and growth in many different cell types shown both in vitro and in vivo. Currently, treatment regimens are used in the clinic for a variety of ailments, including wound healing. However, most protocols treat an anatomical site without consid...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201600025

    authors: Engel KW,Khan I,Arany PR

    更新日期:2016-12-01 00:00:00

  • Nanofluidic devices towards single DNA molecule sequence mapping.

    abstract::Nanofluidics enables the imaging of stretched single molecules with potential applications for single molecule sequence mapping. Lab-on-a-chip devices for single cell trapping and lyzing, genomic DNA extraction from single cells, and optical mapping of genomic length DNA has been demonstrated separately. Yet the pursu...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章,评审

    doi:10.1002/jbio.201200050

    authors: Marie R,Kristensen A

    更新日期:2012-08-01 00:00:00

  • Quantitative phase imaging of cells in a flow cytometry arrangement utilizing Michelson interferometer-based off-axis digital holographic microscopy.

    abstract::We combined Michelson-interferometer-based off-axis digital holographic microscopy (DHM) with a common flow cytometry (FCM) arrangement. Utilizing object recognition procedures and holographic autofocusing during the numerical reconstruction of the acquired off-axis holograms, sharply focused quantitative phase images...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201900085

    authors: Min J,Yao B,Trendafilova V,Ketelhut S,Kastl L,Greve B,Kemper B

    更新日期:2019-09-01 00:00:00

  • Development and application of LED arrays for use in phototherapy research.

    abstract::Lasers/LEDs demonstrate therapeutic effects for a range of biomedical applications. However, a consensus on effective light irradiation parameters and efficient and reliable measurement techniques remain limited. The objective here is to develop, characterise and demonstrate the application of LED arrays in order to p...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201600273

    authors: Hadis MA,Cooper PR,Milward MR,Gorecki PC,Tarte E,Churm J,Palin WM

    更新日期:2017-11-01 00:00:00

  • Some selected quantitative methods of thermal image analysis in Matlab.

    abstract::The paper presents a new algorithm based on some selected automatic quantitative methods for analysing thermal images. It shows the practical implementation of these image analysis methods in Matlab. It enables to perform fully automated and reproducible measurements of selected parameters in thermal images. The paper...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201500224

    authors: Koprowski R

    更新日期:2016-05-01 00:00:00

  • Determination of the metabolic index using the fluorescence lifetime of free and bound nicotinamide adenine dinucleotide using the phasor approach.

    abstract::The fluorescence lifetime of nicotinamide adenine dinucleotide (NADH) is commonly used in conjunction with the phasor approach as a molecular biomarker to provide information on cellular metabolism of autofluorescence imaging of cells and tissue. However, in the phasor approach, the bound and free lifetime defining th...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201900156

    authors: Ranjit S,Malacrida L,Stakic M,Gratton E

    更新日期:2019-11-01 00:00:00

  • Molecular changes during pollen germination can be monitored by Raman microspectroscopy.

    abstract::The processes associated with pollen germination were studied in vitro for two tree species, Salix caprea and Fraxinus excelsior under different nutrient conditions. The results provide evidence of changes in chemical composition of the pollen grains during germination. From the comparison of spectra of the pollen gra...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201000031

    authors: Schulte F,Panne U,Kneipp J

    更新日期:2010-08-01 00:00:00

  • Role of blood oxygenation saturation in ovarian cancer diagnosis using multi-spectral photoacoustic tomography.

    abstract::In photoacoustic tomography (PAT), a tunable laser typically illuminates the tissue at multiple wavelengths, and the received photoacoustic waves are used to form functional images of relative total haemoglobin (rHbT) and blood oxygenation saturation (%sO2 ). Due to measurement errors, the estimation of these paramete...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.202000368

    authors: Amidi E,Yang G,Uddin KMS,Luo H,Middleton W,Powell M,Siegel C,Zhu Q

    更新日期:2020-12-30 00:00:00

  • Monitoring the efficacy of antimicrobial photodynamic therapy in a murine model of cutaneous leishmaniasis using L. major expressing GFP.

    abstract::A murine model of cutaneous leishmaniasis with green fluorescent protein positive (GFP+) L. major enables the monitoring of parasitic load via measurements of GFP fluorescence intensity, allowing for a faster and more efficient way of monitoring the clinical outcome of photodynamic therapy (PDT). This model may provid...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201000008

    authors: Latorre-Esteves E,Akilov OE,Rai P,Beverley SM,Hasan T

    更新日期:2010-06-01 00:00:00

  • Widefield fluorescence lifetime imaging of protoporphyrin IX for fluorescence-guided neurosurgery: An ex vivo feasibility study.

    abstract::Achieving a maximal safe extent of resection during brain tumor surgery is the goal for improved patient prognosis. Fluorescence-guided neurosurgery using 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX has thereby become a valuable tool enabling a high frequency of complete resections and a prolonged progress...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800378

    authors: Erkkilä MT,Bauer B,Hecker-Denschlag N,Madera Medina MJ,Leitgeb RA,Unterhuber A,Gesperger J,Roetzer T,Hauger C,Drexler W,Widhalm G,Andreana M

    更新日期:2019-06-01 00:00:00

  • In vivo imaging of hematopoietic stem cells and their microenvironment.

    abstract::In this review we provide a description of the basic concepts and paradigms currently constituting the foundations of adult stem cell biology, and discuss the role that live imaging techniques have in the development of the field. We focus on live imaging of hematopoietic stem cells (HSCs) as the basic biology and cli...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章,评审

    doi:10.1002/jbio.200910072

    authors: Lo Celso C,Wu JW,Lin CP

    更新日期:2009-11-01 00:00:00

  • Chemically-specific dual/differential CARS micro-spectroscopy of saturated and unsaturated lipid droplets.

    abstract::We have investigated the ability of dual-frequency Coherent Antistokes Raman Scattering (D-CARS) micro-spectroscopy, based on femtosecond pulses (100 fs or 5 fs) spectrally focussed by glass dispersion, to distinguish the chemical composition of micron-sized lipid droplets consisting of different triglycerides types (...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201200197

    authors: Di Napoli C,Masia F,Pope I,Otto C,Langbein W,Borri P

    更新日期:2014-01-01 00:00:00

  • Laser exposure of gold nanorods can induce intracellular calcium transients.

    abstract::Uncoated and poly(styrene sulphonate) (PSS)-coated gold nanorods were taken up by NG108-15 neuronal cells. Exposure to 780 nm laser light at the plasmon resonance wavelength of the gold nanorods was found to induce intracellular Ca(2+) transients. The higher Ca(2+) peaks were observed at lower laser doses, with the hi...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201300043

    authors: Paviolo C,Haycock JW,Cadusch PJ,McArthur SL,Stoddart PR

    更新日期:2014-10-01 00:00:00

  • Measurement of cartilage sub-component distributions through the surface by Raman spectroscopy-based multivariate analysis.

    abstract::Articular cartilage posesses unique material properties due to a complex depth-dependent composition of sub-components. Raman spectroscopy has proven valuable in quantifying this composition through cartilage cross-sections. However, cross-sectioning requires tissue destruction and is not practical in situ. In this wo...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.202000289

    authors: Mason D,Murugkar S,Speirs AD

    更新日期:2021-01-01 00:00:00

  • Characterization of the optical properties of color pastes for the design of optical phantoms mimicking biological tissue.

    abstract::Clinicians need a way to rapidly and reliably test the correct functioning of near-infrared spectroscopy (NIRS)-based oximeters. Therefore, optical phantoms for quality assessment of NIRS oximeters are needed. The fabrication of such phantoms that mimic the optical properties of biological tissue in the NIR range repr...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800300

    authors: Tomm N,Ahnen L,Isler H,Kleiser S,Karen T,Ostojic D,Wolf M,Scholkmann F

    更新日期:2019-04-01 00:00:00

  • In vivo noninvasive visualization of retinal perfusion dysfunction in murine cerebral malaria by camera-phone laser speckle imaging.

    abstract::Cerebral malaria (CM) is a severe complication of Plasmodium falciparum infection associated with impaired cerebral blood flow. Visualization of the eye vasculature, which is embryologically derived from that of the brain, is used clinically to diagnose the syndrome. Here, we introduce camera-phone laser speckle imagi...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800098

    authors: Remer I,Pierre-Destine LF,Tay D,Golightly LM,Bilenca A

    更新日期:2019-01-01 00:00:00

  • Laser imaging polarimetry of nacre.

    abstract::Nacre is a complex biomaterial made of aragonite-tablet bricks and organic mortar that is considerably resilient against breakage. Nacre has been studied with a wide range of laboratory techniques, leading to understanding key fundamentals and informing the creation of bio-inspired materials. In this article, we prese...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800026

    authors: Jones JA,Metzler RA,D'Addario AJ,Burgess C,Regan B,Spano S,Cvarch BA,Galvez EJ

    更新日期:2018-10-01 00:00:00

  • Hybrid method of strain estimation in optical coherence elastography using combined sub-wavelength phase measurements and supra-pixel displacement tracking.

    abstract::A novel hybrid method which combines sub-wavelength-scale phase measurements and pixel-scale displacement tracking for robust strain mapping in compressional optical coherence elastography is proposed. Unlike majority of OCE methods it does not rely on initial reconstruction of displacements and does not suffer from t...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201500203

    authors: Zaitsev VY,Matveyev AL,Matveev LA,Gelikonov GV,Gubarkova EV,Gladkova ND,Vitkin A

    更新日期:2016-05-01 00:00:00