Nanofluidic devices towards single DNA molecule sequence mapping.

abstract：:FTIR spectroscopy is a powerful diagnostic tool that can also derive biochemical signatures of a wide range of cellular materials, such as cytology, histology, live cells, and biofluids. However, while classification is a well-established subject, biomarker identification lacks standards and validation of its methods....

journal_title：Journal of biophotonics

authors： Trevisan J,Park J,Angelov PP,Ahmadzai AA,Gajjar K,Scott AD,Carmichael PL,Martin FL

更新日期：2014-04-01 00:00:00

abstract：:Surface-enhanced Raman scattering (SERS) spectroscopy possesses the most promising advantage of multiplex detection for biosensing applications, which is achieved due to the narrow 'fingerprint' Raman spectra from the analyte molecules. We developed an ultrasensitive platform for the multiplex detection of cancer biom...

journal_title：Journal of biophotonics

authors： Dinish US,Balasundaram G,Chang YT,Olivo M

更新日期：2014-11-01 00:00:00

abstract：:Lasers are used in dentistry for a variety of indications. One of these is the disinfection of root canals or the sterilization of residual caries. Many studies have demonstrated the capacity to kill bacteria for lasers but the fundamental mechanism of the laser effect remains quite unclear. With our experiments we wa...

journal_title：Journal of biophotonics

authors： Hibst R,Graser R,Udart M,Stock K

更新日期：2010-06-01 00:00:00

abstract：:Stimulated Raman scattering (SRS) has been applied to unstained samples of articular cartilage enabling the investigation of living cells within fresh tissue. Hyperspectral SRS measurements over the CH vibrational region showed variations in protein and lipid content within the cells, pericellular matrix and interterr...

journal_title：Journal of biophotonics

authors： Mansfield J,Moger J,Green E,Moger C,Winlove CP

更新日期：2013-10-01 00:00:00

abstract：:Limb perfusion monitoring is critical for diabetes mellitus (DM) patients as they are vulnerable to vascular complications due to prolonged hyperglycemia. However, current clinical approaches are ineffective in vascular imaging and in assessing vascular function in lower limbs. In this work, a concave ultrasound trans...

journal_title：Journal of biophotonics

authors： Yang J,Zhang G,Shang Q,Wu M,Huang L,Jiang H

更新日期：2020-08-01 00:00:00

abstract：:Osteoporosis is a major public health problem worldwide. Here, we present a quantitative multispectral photoacoustic method for the evaluation of bone pathologies which has significant advantages over pure ultrasonic or pure optical methods as it provides both molecular information and bone mechanical status. This is ...

journal_title：Journal of biophotonics

authors： Steinberg I,Turko N,Levi O,Gannot I,Eyal A

更新日期：2016-09-01 00:00:00

abstract：:Drowsy driving contributes to ~20% of all traffic accidents worldwide. Onsite monitoring the mental condition of a driver and forewarning may be a preventive solution to reduce occurrence of drowsiness and potential accidents. Functional near-infrared spectroscopy (fNIRS) has been successfully utilized in hemodynamics...

journal_title：Journal of biophotonics

authors： Li T,Lin Y,Gao Y,Zhong F

更新日期：2018-12-01 00:00:00

abstract：:5-aminolevulinic acid (ALA) and its methylated ester (MAL) are the most common topical agents used in photodynamic therapy (PDT) as precursors of the photosensitizer protoporphyrin IX (PpIX). The induction of newly PpIX depends on incubation time of each photosensitizer in the tissue and the presence of high intralesi...

journal_title：Journal of biophotonics

authors： Lima CA,Goulart VP,Bechara EJ,Correa L,Zezell DM

更新日期：2016-12-01 00:00:00

abstract：:The purpose of this study was to evaluate the tomographic features of postrefractive surgery eyes. This was a retrospective evaluation of clinical data. Three patients with post-LASIK (laser-assisted in situ keratomileusis) and two patients with post-SMILE (small incision lenticule extraction) ectasia were imaged with...

journal_title：Journal of biophotonics

authors： Khamar P,Dalal R,Chandapura R,Francis M,Shetty R,Nelson EJR,Nuijts RMMA,Sinha Roy A

更新日期：2019-02-01 00:00:00

abstract：:Quantitative phase imaging (QPI) is an emerging modality, which enables the identification of abnormalities in tissue based on optical properties. QPI can be applied to any biological specimen due to its label-free imaging capability, but its use in stained tissue is unclear. Here, we study the variability of QPI with...

journal_title：Journal of biophotonics

authors： Ban S,Min E,Ahn Y,Popescu G,Jung W

更新日期：2018-08-01 00:00:00

abstract：:Clinicians need a way to rapidly and reliably test the correct functioning of near-infrared spectroscopy (NIRS)-based oximeters. Therefore, optical phantoms for quality assessment of NIRS oximeters are needed. The fabrication of such phantoms that mimic the optical properties of biological tissue in the NIR range repr...

journal_title：Journal of biophotonics

authors： Tomm N,Ahnen L,Isler H,Kleiser S,Karen T,Ostojic D,Wolf M,Scholkmann F

更新日期：2019-04-01 00:00:00

abstract：:Optical sectioning endoscopy such as confocal endoscopy offers capabilities to obtain three-dimensional (3D) information from various biological samples by discriminating between the desired in-focus signals and out-of-focus background. However, in general confocal images are formed through point-by-point scanning and...

journal_title：Journal of biophotonics

authors： Lin WT,Lin CY,Singh VR,Luo Y

更新日期：2018-11-01 00:00:00

abstract：:Biophotonics is a highly interdisciplinary field where physicists, chemists, biologists, physicians and engineers work together to solve the problems appearing in biology and medicine. In China, the Biophotonics discipline is often referred to as Biomedical Photonics, under the first-level disciplines Biomedical Engin...

journal_title：Journal of biophotonics

authors： Shi H,Luo Q

更新日期：2017-12-01 00:00:00

abstract：:Retinoblastoma (RB) is a rare form of cancer of the retina most prevalent in young children. We successfully show that laser-induced cell disruption, mediated by gold plasmonic nanoparticle (NP), is a potential and efficient therapy to kill the cancerous cells. The proof of concept is demonstrated in vitro on cultured...

journal_title：Journal of biophotonics

authors： Darviot C,Hardy P,Meunier M

更新日期：2019-11-01 00:00:00

abstract：:Methods of nonlinear optics provide a vast arsenal of tools for label-free brain imaging, offering a unique combination of chemical specificity, the ability to detect fine morphological features, and an unprecedentedly high, subdiffraction spatial resolution. While these techniques provide a rapidly growing platform f...

journal_title：Journal of biophotonics

authors： Lanin AA,Pochechuev MS,Chebotarev AS,Kelmanson IV,Belousov VV,Zheltikov AM

更新日期：2019-11-01 00:00:00

abstract：:Dynamic follow-up of exogenous molecules permeation through the skin is one among many competing applications for confocal Raman microspectroscopy. Previous studies showed the feasibility of tracking actives through the skin; the next step should be recording in vivo kinetics. Thus, we conducted a study to evaluate th...

journal_title：Journal of biophotonics

authors： Tfaili S,Josse G,Angiboust JF,Manfait M,Piot O

更新日期：2014-09-01 00:00:00

abstract：:Basidiomycetes, that is, mushroom-type fungi, are known to produce pigments in response to environmental impacts. As antioxidants with a high level of unsaturation, these compounds can neutralize highly oxidative species. In the event of close contact with other microbes, the enzymatically controlled pigment productio...

journal_title：Journal of biophotonics

authors： Tauber JP,Matthäus C,Lenz C,Hoffmeister D,Popp J

更新日期：2018-06-01 00:00:00

abstract：:This contribution covers recent original research papers in the biophotonics field. The content is organized into main techniques such as multiphoton microscopy, Raman spectroscopy, infrared spectroscopy, optical coherence tomography and photoacoustic tomography, and their applications in the context of fluid, cell, t...

journal_title：Journal of biophotonics

authors： Krafft C

更新日期：2016-12-01 00:00:00

abstract：:For a precise manipulation of particles and cells with laser light as well as for the understanding and the control of the underlying processes it is important to visualize and quantify the response of the specimens. Thus, we investigated if digital holographic microscopy (DHM) can be used in combination with microflu...

journal_title：Journal of biophotonics

authors： Kemper B,Langehanenberg P,Höink A,von Bally G,Wottowah F,Schinkinger S,Guck J,Käs J,Bredebusch I,Schnekenburger J,Schütze K

更新日期：2010-07-01 00:00:00

abstract：:We describe a novel, minimally invasive laser technology for skin rejuvenation by creating isolated microscopic lesions within tissue below the epidermis using laser induced optical breakdown. Using an in-house built prototype device, tightly focused near-infrared laser pulses are used to create optical breakdown in t...

journal_title：Journal of biophotonics

authors： Habbema L,Verhagen R,Van Hal R,Liu Y,Varghese B

更新日期：2012-02-01 00:00:00

abstract：:A murine model of cutaneous leishmaniasis with green fluorescent protein positive (GFP+) L. major enables the monitoring of parasitic load via measurements of GFP fluorescence intensity, allowing for a faster and more efficient way of monitoring the clinical outcome of photodynamic therapy (PDT). This model may provid...

journal_title：Journal of biophotonics

authors： Latorre-Esteves E,Akilov OE,Rai P,Beverley SM,Hasan T

更新日期：2010-06-01 00:00:00

abstract：:A Monte Carlo simulation was adapted to specify a skin model with pigmented epidermis, dermis with low baseline blood content, and vessels of a vascular lesion with an average added blood volume fraction of 5%. In the study, the lesion vessel diameters were increased and the number of lesion vessels decreased, such th...

journal_title：Journal of biophotonics

authors： Jacques SL

更新日期：2010-01-01 00:00:00

abstract：:Whole slide imaging (WSI) has moved digital pathology closer to diagnostic practice in recent years. Due to the inherent tissue topography variability, accurate autofocusing remains a critical challenge for WSI and automated microscopy systems. The traditional focus map surveying method is limited in its ability to ac...

journal_title：Journal of biophotonics

authors： Bian Z,Guo C,Jiang S,Zhu J,Wang R,Song P,Zhang Z,Hoshino K,Zheng G

更新日期：2020-12-01 00:00:00

abstract：:In vivo imaging of cerebral vasculature is highly vital for clinicians and medical researchers alike. For a number of years non-invasive optical-based imaging of brain vascular network by using standard fluorescence probes has been considered as impossible. In the current paper controverting this paradigm, we present ...

journal_title：Journal of biophotonics

authors： Kalchenko V,Israeli D,Kuznetsov Y,Meglinski I,Harmelin A

更新日期：2015-11-01 00:00:00

abstract：:The investigation of lung dynamics on alveolar scale is crucial for the understanding and treatment of lung diseases, such as acute lung injury and ventilator induced lung injury, and to promote the development of protective ventilation strategies. One approach to this is the establishment of numerical simulations of ...

journal_title：Journal of biophotonics

authors： Kirsten L,Gaertner M,Schnabel C,Meissner S,Koch E

更新日期：2013-02-01 00:00:00

abstract：:The aim of this study was to evaluate whether OCT topography of the Bowman's layer and artificial intelligence (AI) can result in better diagnosis of forme fruste (FFKC) and clinical keratoconus (KC). Normal (n = 221), FFKC (n = 72) and KC (n = 116) corneas were included. Some of the FFKC and KC patients had the fello...

journal_title：Journal of biophotonics

authors： Chandapura R,Salomão MQ,Ambrósio R Jr,Swarup R,Shetty R,Sinha Roy A

更新日期：2019-10-01 00:00:00

abstract：:Laser treatment on a large size of prostate gland often encounters significant bleeding that can prolong the entire procedure and cause urinary complications. The current study investigates the feasibility of dual-wavelength (532 and 980 nm) application to achieve rapid hemostasis for 532-nm laser prostatectomy. Porci...

journal_title：Journal of biophotonics

authors： Hwang J,Kim H,Truong GV,Xuan J,Hasenberg T,Kang HW

更新日期：2018-04-01 00:00:00

abstract：:We present a noninvasive and noncontacting biosensor using Wavelength Modulated Differential Photothermal Radiometry (WM-DPTR) to monitor blood glucose concentration (BGC) through interstitial fluid (ISF) probing in human middle fingers. WM-DPTR works in the interference-free mid-infrared range with differential wavel...

journal_title：Journal of biophotonics

authors： Guo X,Zhang D,Shojaei-Asanjan K,Sivagurunathan K,Melnikov A,Song P,Mandelis A

更新日期：2019-07-01 00:00:00

abstract：:We combined Michelson-interferometer-based off-axis digital holographic microscopy (DHM) with a common flow cytometry (FCM) arrangement. Utilizing object recognition procedures and holographic autofocusing during the numerical reconstruction of the acquired off-axis holograms, sharply focused quantitative phase images...

journal_title：Journal of biophotonics

authors： Min J,Yao B,Trendafilova V,Ketelhut S,Kastl L,Greve B,Kemper B

更新日期：2019-09-01 00:00:00

abstract：:As the field of tissue engineering evolves, there will be an increasingly important need to visualize and track the complex dynamic changes that occur within three-dimensional constructs. Optical coherence tomography (OCT), as an emerging imaging technology applied to biological materials, offers a number of significa...

journal_title：Journal of biophotonics

authors： Liang X,Graf BW,Boppart SA

更新日期：2009-11-01 00:00:00