Cell lineage responses to photobiomodulation therapy.

Abstract:

:Photobiomodulation (PBM) therapy has been noted to promote cell proliferation and growth in many different cell types shown both in vitro and in vivo. Currently, treatment regimens are used in the clinic for a variety of ailments, including wound healing. However, most protocols treat an anatomical site without considering individual cell types constituting the target tissues. This study investigates the maximal dose threshold for oral keratinocyte and fibroblast cell types treated with near-infrared laser therapy. We observed keratinocytes have increased sensitivity to laser irradiances (>0.047 W/cm2 , 300 sec, 14.2 J/cm2 ) compared to the fibroblast cells (>0.057 W/cm2 , 300 sec, 15.1 J/cm2 ) (p < 0.0001). Laser treatments were noted to generate increased reactive oxygen species (ROS) levels in keratinocytes compared to fibroblasts that appeared to inversely correlate with higher basal catalase expression. To validate these observations, melatonin was used to treat keratinocytes to induce catalase activity (p < 0.0001). Increased melatonin-induced catalase levels were noted to significantly improve keratinocyte survival to phototoxic laser doses. These observations suggest that clinical laser dosing should account for differential effects of lasers on individual cell types to improve safety and clinical efficacy of PBM therapy.

journal_name

J Biophotonics

journal_title

Journal of biophotonics

authors

Engel KW,Khan I,Arany PR

doi

10.1002/jbio.201600025

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

1148-1156

issue

11-12

eissn

1864-063X

issn

1864-0648

journal_volume

9

pub_type

杂志文章
  • Rapid discrimination of colon cancer cells with single base mutation in KRAS gene segment using laser tweezers Raman spectroscopy.

    abstract::Laser tweezers Raman spectroscopy (LTRS) as a label-free and noninvasive technology has been proven to be an ideal tool for analysis of single living cells, which provides important fingerprint information without interference from surrounding environments. For the first time, LTRS system was successfully used to exam...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800332

    authors: Liu M,Liu X,Huang Z,Tang X,Lin X,Xu Y,Chen G,Kwok HF,Lin Y,Feng S

    更新日期:2019-03-01 00:00:00

  • Longtime driving induced cerebral hemodynamic elevation and behavior degradation as assessed by functional near-infrared spectroscopy and a voluntary attention test.

    abstract::Drowsy driving contributes to ~20% of all traffic accidents worldwide. Onsite monitoring the mental condition of a driver and forewarning may be a preventive solution to reduce occurrence of drowsiness and potential accidents. Functional near-infrared spectroscopy (fNIRS) has been successfully utilized in hemodynamics...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800160

    authors: Li T,Lin Y,Gao Y,Zhong F

    更新日期:2018-12-01 00:00:00

  • Towards automated cancer screening: Label-free classification of fixed cell samples using wavelength modulated Raman spectroscopy.

    abstract::The ability to provide quantitative, objective and automated pathological analysis would provide enormous benefits for national cancer screening programmes, in terms of both resource reduction and improved patient wellbeing. The move towards molecular pathology through spectroscopic methods shows great promise, but ha...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201700244

    authors: Woolford L,Chen M,Dholakia K,Herrington CS

    更新日期:2018-04-01 00:00:00

  • Photoacoustically-guided photothermal killing of mosquitoes targeted by nanoparticles.

    abstract::In biomedical applications, nanoparticles have demonstrated the potential to eradicate abnormal cells in small localized pathological zones associated with cancer or infections. Here, we introduce a method for nanotechnology-based photothermal (PT) killing of whole organisms considered harmful to humans or the environ...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201200199

    authors: Foster SR,Galanzha EI,Totten DC,Beneš H,Shmookler Reis RJ,Zharov VP

    更新日期:2014-07-01 00:00:00

  • Optical assessment of cutaneous blood volume depends on the vessel size distribution: a computer simulation study.

    abstract::A Monte Carlo simulation was adapted to specify a skin model with pigmented epidermis, dermis with low baseline blood content, and vessels of a vascular lesion with an average added blood volume fraction of 5%. In the study, the lesion vessel diameters were increased and the number of lesion vessels decreased, such th...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.200900085

    authors: Jacques SL

    更新日期:2010-01-01 00:00:00

  • Laser exposure of gold nanorods can induce intracellular calcium transients.

    abstract::Uncoated and poly(styrene sulphonate) (PSS)-coated gold nanorods were taken up by NG108-15 neuronal cells. Exposure to 780 nm laser light at the plasmon resonance wavelength of the gold nanorods was found to induce intracellular Ca(2+) transients. The higher Ca(2+) peaks were observed at lower laser doses, with the hi...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201300043

    authors: Paviolo C,Haycock JW,Cadusch PJ,McArthur SL,Stoddart PR

    更新日期:2014-10-01 00:00:00

  • Optical emission of 223 Radium: in vitro and in vivo preclinical applications.

    abstract::223 Radium (223 Ra) is widely used in nuclear medicine to treat patients with osseous metastatic prostate cancer. In clinical practice 223 Ra cannot be imaged directly; however, gamma photons produced by its short-lived daughter nuclides can be captured by conventional gamma cameras. In this work, we show that 223 Ra ...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201700209

    authors: Boschi F,De Sanctis F,Spinelli AE

    更新日期:2018-04-01 00:00:00

  • Microfluidics and photonics for Bio-System-on-a-Chip: a review of advancements in technology towards a microfluidic flow cytometry chip.

    abstract::Microfluidics and photonics come together to form a field commonly referred to as 'optofluidics'. Flow cytometry provides the field with a technology base from which both microfluidic and photonic components be developed and integrated into a useful device. This article reviews some of the more recent developments to ...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章,评审

    doi:10.1002/jbio.200810018

    authors: Godin J,Chen CH,Cho SH,Qiao W,Tsai F,Lo YH

    更新日期:2008-10-01 00:00:00

  • Biocompatible astaxanthin as novel contrast agent for biomedical imaging.

    abstract::Photoacoustic imaging (PAI) is a hybrid imaging modality with high resolution and sensitivity that can be beneficial for cancer staging. Due to insufficient endogenous photoacoustic (PA) contrast, the development of exogenous agents is critical in targeting cancerous tumors. The current study demonstrates the feasibil...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201600159

    authors: Nguyen VP,Park S,Oh J,Wook Kang H

    更新日期:2017-08-01 00:00:00

  • Monitoring the biochemical changes occurring to human keratinocytes exposed to solar radiation by Raman spectroscopy.

    abstract::Solar radiation exposure is recognised to be a significant contributor to the development of skin cancer. Monitoring the simultaneous and consecutive mechanisms of interaction could provide a greater understanding of the process of photocarcinogenesis. This work presents an analysis of the biochemical and morphologica...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.202000337

    authors: Lopez-Gonzalez U,Casey A,J Byrne H

    更新日期:2020-10-24 00:00:00

  • Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography.

    abstract::Optical coherence tomography (OCT) is a well-developed technology that utilizes near-infrared light to reconstruct three-dimensional images of biological tissues with micrometer resolution. Improvements of the imaging contrast of the OCT technique are able to further widen its extensive biomedical applications. In thi...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201600047

    authors: Zhang J,Liu J,Wang LM,Li ZY,Yuan Z

    更新日期:2017-06-01 00:00:00

  • Activity assessment of root caries lesions with thermal and near-IR imaging methods.

    abstract::The purpose of this study was to evaluate thermal and near-infrared (NIR) reflectance imaging methods for the assessment of the activity of root caries lesions. In addition, changes in the lesion structure were monitored with polarization sensitive optical coherence tomography (PS-OCT). Artificial bovine and natural r...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201500333

    authors: Lee RC,Darling CL,Staninec M,Ragadio A,Fried D

    更新日期:2017-03-01 00:00:00

  • Biophotonics in China.

    abstract::Biophotonics is a highly interdisciplinary field where physicists, chemists, biologists, physicians and engineers work together to solve the problems appearing in biology and medicine. In China, the Biophotonics discipline is often referred to as Biomedical Photonics, under the first-level disciplines Biomedical Engin...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201790012

    authors: Shi H,Luo Q

    更新日期:2017-12-01 00:00:00

  • Visualizing the "sandwich" structure of osteocytes in their native environment deep in bone in vivo.

    abstract::Osteocytes are the most abundant cells in bone and always the focus of bone research. They are embedded in the highly scattering mineralized bone matrix. Consequently, visualizing osteocytes deep in bone with subcellular resolution poses a major challenge for in vivo bone research. Here we overcome this challenge by d...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800360

    authors: Wang K,Du Y,Liu H,Gan M,Tong S,Wen W,Zhuang Z,Qiu P

    更新日期:2019-04-01 00:00:00

  • CTAB enhancement of FRET in DNA structures.

    abstract::The effect of cetyl-trimethylammonium bromide (CTAB) on enhancing the fluorescence resonance energy transfer (FRET) between two dye-conjugated DNA strands was studied using fluorescence emission spectroscopy and dynamic light scattering (DLS). For hybridized DNA where one strand is conjugated with a TAMRA donor and th...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201500221

    authors: Oh T,Takahashi T,Kim S,Heller MJ

    更新日期:2016-01-01 00:00:00

  • Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study.

    abstract::The capabilities of cross-polarization optical coherence tomography (CP OCT) for early bladder-cancer detection are assessed in statistical study and compared with the traditional OCT. Unlike the traditional OCT that demonstrates images only in copolarization, CP OCT acquires images in cross-polarization and copolariz...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201000088

    authors: Gladkova N,Streltsova O,Zagaynova E,Kiseleva E,Gelikonov V,Gelikonov G,Karabut M,Yunusova K,Evdokimova O

    更新日期:2011-08-01 00:00:00

  • Characterization of the optical properties of color pastes for the design of optical phantoms mimicking biological tissue.

    abstract::Clinicians need a way to rapidly and reliably test the correct functioning of near-infrared spectroscopy (NIRS)-based oximeters. Therefore, optical phantoms for quality assessment of NIRS oximeters are needed. The fabrication of such phantoms that mimic the optical properties of biological tissue in the NIR range repr...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800300

    authors: Tomm N,Ahnen L,Isler H,Kleiser S,Karen T,Ostojic D,Wolf M,Scholkmann F

    更新日期:2019-04-01 00:00:00

  • Analysis of light scattering from human breast tissue using a custom dual-optical scanning near-field optical microscope.

    abstract::In this paper we introduce a custom scanning near-field optical microscope (SNOM) that simultaneously collects reflection and transmission near-field images along with topography. This dual-optical SNOM uses a bent probe, which allows for axial reflection imaging, accurate surface scanning, and easy identification of ...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201000022

    authors: Kyle JR,Kyle MD,Raghavan R,Budak G,Ozkan CS,Ozkan M

    更新日期:2011-03-01 00:00:00

  • Raman spectroscopy investigation of biochemical changes in tumor spheroids with aging and after treatment with staurosporine.

    abstract::There has been increasing use of in vitro cell culture models that more realistically replicate the three-dimensional (3D) environment found in vivo. Multicellular tumor spheroids (MTS) using cell lines or patient-derived organoids have become an important in vitro drug development tool, where cells are grown in a 3D ...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201800201

    authors: Jamieson LE,Harrison DJ,Campbell CJ

    更新日期:2019-05-01 00:00:00

  • Effect of tissue staining in quantitative phase imaging.

    abstract::Quantitative phase imaging (QPI) is an emerging modality, which enables the identification of abnormalities in tissue based on optical properties. QPI can be applied to any biological specimen due to its label-free imaging capability, but its use in stained tissue is unclear. Here, we study the variability of QPI with...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201700402

    authors: Ban S,Min E,Ahn Y,Popescu G,Jung W

    更新日期:2018-08-01 00:00:00

  • Treatment of tumor in lymph nodes using near-infrared laser light-activated thermosensitive liposome-encapsulated doxorubicin and gold nanorods.

    abstract::Tumor metastasis to lymph nodes is an important contributory factor for cancer-related deaths despite recent developments in cancer therapy. In this study, we demonstrate that tumor in the proper axillary lymph node (PALN) of the mouse can be treated by the application of external laser light to trigger the unloading ...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201600241

    authors: Matsuki D,Adewale O,Horie S,Okajima J,Komiya A,Oluwafemi O,Maruyama S,Mori S,Kodama T

    更新日期:2017-12-01 00:00:00

  • Sparse-graph manifold learning method for bioluminescence tomography.

    abstract::In preclinical researches, bioluminescence tomography (BLT) has widely been used for tumor imaging and monitoring, imaged-guided tumor therapy, and so forth. For these biological applications, both tumor spatial location and morphology analysis are the leading problems needed to be taken into account. However, most ex...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201960218

    authors: Guo H,Gao L,Yu J,He X,Wang H,Zheng J,Yang X

    更新日期:2020-04-01 00:00:00

  • In vivo multimodal microscopy for detecting bone-marrow-derived cell contribution to skin regeneration.

    abstract::Bone-marrow (BM)-derived cells have been shown to be capable of aiding skin regeneration in vivo by differentiating into keratinocytes. However, the conditions under which this occurs are not fully understood. Characterizing innate mechanisms of skin regeneration by stem cells in vivo is important for the area of stem...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201200240

    authors: Graf BW,Bower AJ,Chaney EJ,Marjanovic M,Adie SG,De Lisio M,Valero MC,Boppart MD,Boppart SA

    更新日期:2014-01-01 00:00:00

  • A silicon photonic biosensor using phase-shifted Bragg gratings in slot waveguide.

    abstract::We present a novel silicon photonic biosensor using phase-shifted Bragg gratings in a slot waveguide. The optical field is concentrated inside the slot region, leading to efficient light-matter interaction. The Bragg gratings are formed with sidewall corrugations on the outside of the waveguide, and a phase shift is i...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201300012

    authors: Wang X,Flueckiger J,Schmidt S,Grist S,Fard ST,Kirk J,Doerfler M,Cheung KC,Ratner DM,Chrostowski L

    更新日期:2013-10-01 00:00:00

  • Fluorescence lifetime metabolic mapping of hypoxia-induced damage in pancreatic pseudo-islets.

    abstract::Pancreatic islet isolation from donor pancreases is an essential step for the transplantation of insulin-secreting β-cells as a therapy to treat type 1 diabetes mellitus. This process however damages islet basement membranes, which can lead to islet dysfunction or death. Posttransplantation, islets are further stresse...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.202000375

    authors: Zbinden A,Carvajal Berrio DA,Urbanczyk M,Layland SL,Bosch M,Fliri S,Lu CE,Jeyagaran A,Loskill P,Duffy GP,Schenke-Layland K

    更新日期:2020-12-01 00:00:00

  • Epithelium segmentation and automated Gleason grading of prostate cancer via deep learning in label-free multiphoton microscopic images.

    abstract::In the current clinical care practice, Gleason grading system is one of the most powerful prognostic predictors for prostate cancer (PCa). The grading system is based on the architectural pattern of cancerous epithelium in histological images. However, the standard procedure of histological examination often involves ...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201900203

    authors: Yang Q,Xu Z,Liao C,Cai J,Huang Y,Chen H,Tao X,Huang Z,Chen J,Dong J,Zhu X

    更新日期:2020-02-01 00:00:00

  • Automatic and label-free identification of blood vessels in gliomas using the combination of multiphoton microscopy and image analysis.

    abstract::Currently, the targeted treatment of tumor based on the tumor microenvironment is newly developed. Blood vessels are the key parts in the tumor microenvironment, which is taken as a new visible target for tumor therapy. Multiphoton microscopy (MPM), based on the second harmonic generation and two-photon excited fluore...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201900006

    authors: Fang N,Wu Z,Wang X,Kang D,Li L,Chen Y,Zheng X,Cai S,Liu X,Chen Z,Tu H,Lin Y,Chen J

    更新日期:2019-09-01 00:00:00

  • Artifact-free objective-type multicolor total internal reflection fluorescence microscopy with light-emitting diode light sources-Part I.

    abstract::Total internal reflection fluorescence excitation (TIRF) microscopy allows the selective observation of fluorescent molecules in immediate proximity to an interface between different refractive indices. Objective-type or prism-less TIRF excitation is typically achieved with laser light sources. We here propose a simpl...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201900033

    authors: Kogel A,Kalwa H,Urban N,Schaefer M

    更新日期:2019-11-01 00:00:00

  • Low-level laser therapy stimulates the oxidative burst in human neutrophils and increases their fungicidal capacity.

    abstract::Low-level laser therapy (LLLT) is known to enhance mitochondrial electron transfer and ATP production; thus, this study asked whether LLLT could stimulate the oxidative burst in human neutrophils (PMN) and improve their ability to kill microorganisms. Blood from healthy human subjects was collected and PMN were isolat...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.201600035

    authors: Cerdeira CD,Lima Brigagão MR,Carli ML,de Souza Ferreira C,de Oliveira Isac Moraes G,Hadad H,Costa Hanemann JA,Hamblin MR,Sperandio FF

    更新日期:2016-12-01 00:00:00

  • Evolution of raw meat polarization-based properties by means of Mueller matrix imaging.

    abstract::The possibilities of using Mueller matrix (MM) imaging polarimetry to assess meat quality have not yet been sufficiently explored. In the current study, the fresh porcine muscles are imaged at room temperature with a wide-field MM imaging polarimeter over 26 hours to visualize dynamics of tissue optical properties thr...

    journal_title:Journal of biophotonics

    pub_type: 杂志文章

    doi:10.1002/jbio.202000376

    authors: Peyvasteh M,Popov A,Bykov A,Pierangelo A,Novikova T,Meglinski I

    更新日期:2020-11-21 00:00:00