Abstract:
:A Monte Carlo simulation was adapted to specify a skin model with pigmented epidermis, dermis with low baseline blood content, and vessels of a vascular lesion with an average added blood volume fraction of 5%. In the study, the lesion vessel diameters were increased and the number of lesion vessels decreased, such that the total lesion blood content was constant. The results show that reflectance (R) increases as vessel size increases, even though the blood content is constant. Light cannot penetrate effectively into larger blood vessels, so the interior of the vessel becomes less visible to the light - a result known in the literature. This study did repeated random placement of vessels to learn the variation in R due to variable vessel placement. The coefficient of variation was about 10% due to random placement. R varies with size, even with small vessels, and does not simply apply to large vessels.
journal_name
J Biophotonicsjournal_title
Journal of biophotonicsauthors
Jacques SLdoi
10.1002/jbio.200900085subject
Has Abstractpub_date
2010-01-01 00:00:00pages
75-81issue
1-2eissn
1864-063Xissn
1864-0648journal_volume
3pub_type
杂志文章abstract::A new optical scattering contrast-agent based on polymer-nanoparticle encapsulated silver nanoplates (PESNs) is presented. Silver nanoplates were chosen due to the flexibility of tuning their plasmon frequencies. The polymer coating preserves their physical and optical properties and confers other advantages such as c...
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