In vitro photoacoustic spectroscopy of pulsatile blood flow: Probing the interrelationship between red blood cell aggregation and oxygen saturation.

abstract：:We suggest to use a combination of optical tweezers and single-image quantitative differential interference contrast (DIC) emulated by a spatial light modulator (SLM) to study physiological shape changes in thrombocytes after activation and demonstrate the effectiveness of this system for the given task. A specially d...

journal_title：Journal of biophotonics

authors： Khan S,Jesacher A,Nussbaumer W,Bernet S,Ritsch-Marte M

更新日期：2011-09-01 00:00:00

abstract：:Mucosal lesions of the upper aerodigestive tract usually concern the squamous epithelium of the surface. Many precancerous alterations now designated as potentially malignant are caused by DNA damage resulting from long term exposure to tobacco and alcohol consumption. The distinction from conditions with a similar ph...

journal_title：Journal of biophotonics

authors： Dreyer T,Kreisel M

更新日期：2012-04-01 00:00:00

abstract：:Photodynamic inactivation (PDI) is a promising alternative for combating infections caused by antimicrobial resistant bacteria. Pneumonias are among the most worrisome infections because of their high-mortality rate. Previous studies have demonstrated the feasibility of using PDI with extracorporeal light to treat pne...

journal_title：Journal of biophotonics

authors： Kassab G,Cheburkanov V,Willis J,Moule MG,Kurachi C,Yakovlev V,Cirillo JD,Bagnato VS

更新日期：2020-10-01 00:00:00

abstract：:Several studies have demonstrated the potential of cross-polarization optical coherence tomography (CP-OCT) to quantify the severity of early caries lesions (tooth decay) on tooth surfaces. The purpose of this study is to show that 2D images of the lesion depth and the integrated reflectivity can be used to accurately...

journal_title：Journal of biophotonics

authors： Chan KH,Chan AC,Fried WA,Simon JC,Darling CL,Fried D

更新日期：2015-01-01 00:00:00

abstract：:Photodynamic inactivation of bacteria (PDIB) is considered a new approach for the struggle against multiresistant bacteria. To achieve a sufficient level of bacteria killing, the photosensitizer must attach to and/or penetrate the bacteria and generate a sufficiently high amount of singlet oxygen. To optimize PDIB, th...

journal_title：Journal of biophotonics

authors： Regensburger J,Maisch T,Felgenträger A,Santarelli F,Bäumler W

更新日期：2010-06-01 00:00:00

abstract：:Skin fibrosis, often referred to as skin scarring, is a significant international health problem with limited treatment options. The hallmarks of skin fibrosis are increased fibroblast proliferation, collagen production, and migration speed. Recently published clinical observations indicate that visible red light may ...

journal_title：Journal of biophotonics

authors： Mamalis A,Koo E,Garcha M,Murphy WJ,Isseroff RR,Jagdeo J

更新日期：2016-12-01 00:00:00

abstract：:Quantification of the mucosa oxygenation levels during Endoscopic imaging provides useful physiological/diagnostic information. In this work a method for non-contact quantification of the oxygen saturation index during Endoscopic imaging using three discrete spectral-band in the blue, the green, and the red parts of t...

journal_title：Journal of biophotonics

authors： Fawzy Y

更新日期：2009-12-01 00:00:00

abstract：:Intravascular optical coherence tomography (IV-OCT) is a light-based imaging modality with high resolution, which employs near-infrared light to provide tomographic intracoronary images. Morbidity caused by coronary heart disease is a substantial cause of acute coronary syndrome and sudden cardiac death. The most comm...

journal_title：Journal of biophotonics

authors： Abdolmanafi A,Cheriet F,Duong L,Ibrahim R,Dahdah N

更新日期：2020-01-01 00:00:00

abstract：:An integrated multimodal optical microscope is demonstrated for high-resolution, structural and functional imaging of engineered and natural skin. This microscope incorporates multiple imaging modalities including optical coherence (OCM), multi-photon (MPM), and fluorescence lifetime imaging microscopy (FLIM), enablin...

journal_title：Journal of biophotonics

authors： Zhao Y,Graf BW,Chaney EJ,Mahmassani Z,Antoniadou E,Devolder R,Kong H,Boppart MD,Boppart SA

更新日期：2012-05-01 00:00:00

abstract：:Tumor metastasis to lymph nodes is an important contributory factor for cancer-related deaths despite recent developments in cancer therapy. In this study, we demonstrate that tumor in the proper axillary lymph node (PALN) of the mouse can be treated by the application of external laser light to trigger the unloading ...

journal_title：Journal of biophotonics

authors： Matsuki D,Adewale O,Horie S,Okajima J,Komiya A,Oluwafemi O,Maruyama S,Mori S,Kodama T

更新日期：2017-12-01 00:00:00

abstract：:A murine model of cutaneous leishmaniasis with green fluorescent protein positive (GFP+) L. major enables the monitoring of parasitic load via measurements of GFP fluorescence intensity, allowing for a faster and more efficient way of monitoring the clinical outcome of photodynamic therapy (PDT). This model may provid...

journal_title：Journal of biophotonics

authors： Latorre-Esteves E,Akilov OE,Rai P,Beverley SM,Hasan T

更新日期：2010-06-01 00:00:00

abstract：:In this paper we introduce a custom scanning near-field optical microscope (SNOM) that simultaneously collects reflection and transmission near-field images along with topography. This dual-optical SNOM uses a bent probe, which allows for axial reflection imaging, accurate surface scanning, and easy identification of ...

journal_title：Journal of biophotonics

authors： Kyle JR,Kyle MD,Raghavan R,Budak G,Ozkan CS,Ozkan M

更新日期：2011-03-01 00:00:00

abstract：:We describe a novel, minimally invasive laser technology for skin rejuvenation by creating isolated microscopic lesions within tissue below the epidermis using laser induced optical breakdown. Using an in-house built prototype device, tightly focused near-infrared laser pulses are used to create optical breakdown in t...

journal_title：Journal of biophotonics

authors： Habbema L,Verhagen R,Van Hal R,Liu Y,Varghese B

更新日期：2012-02-01 00:00:00

abstract：:Highly emissive europium complexes with specific endoplasmic reticulum localization potential includes several advantages such as fast uptake, long resident lifetime, low dosage requirement, low cytotoxicity and highly emissive two-photon induced f-f emission imaging. ...

journal_title：Journal of biophotonics

authors： Law GL,Wong KL,Man CW,Tsao SW,Wong WT

更新日期：2009-12-01 00:00:00

abstract：:The paper presents a new algorithm based on some selected automatic quantitative methods for analysing thermal images. It shows the practical implementation of these image analysis methods in Matlab. It enables to perform fully automated and reproducible measurements of selected parameters in thermal images. The paper...

journal_title：Journal of biophotonics

authors： Koprowski R

更新日期：2016-05-01 00:00:00

abstract：:Optical coherence tomography (OCT) imaging shows a significant potential in clinical routines due to its noninvasive property. However, the quality of OCT images is generally limited by inherent speckle noise of OCT imaging and low sampling rate. To obtain high signal-to-noise ratio (SNR) and high-resolution (HR) OCT ...

journal_title：Journal of biophotonics

authors： Qiu B,You Y,Huang Z,Meng X,Jiang Z,Zhou C,Liu G,Yang K,Ren Q,Lu Y

更新日期：2021-01-01 00:00:00

abstract：:We present a pseudo-real-time retinal layer segmentation for high-resolution Sensorless Adaptive Optics-Optical Coherence Tomography (SAO-OCT). Our pseudo-real-time segmentation method is based on Dijkstra's algorithm that uses the intensity of pixels and the vertical gradient of the image to find the minimum cost in ...

journal_title：Journal of biophotonics

authors： Janpongsri W,Huang J,Ng R,Wahl DJ,Sarunic MV,Jian Y

更新日期：2020-08-01 00:00:00

abstract：:Articular cartilage posesses unique material properties due to a complex depth-dependent composition of sub-components. Raman spectroscopy has proven valuable in quantifying this composition through cartilage cross-sections. However, cross-sectioning requires tissue destruction and is not practical in situ. In this wo...

journal_title：Journal of biophotonics

authors： Mason D,Murugkar S,Speirs AD

更新日期：2021-01-01 00:00:00

abstract：:Lasers are used in dentistry for a variety of indications. One of these is the disinfection of root canals or the sterilization of residual caries. Many studies have demonstrated the capacity to kill bacteria for lasers but the fundamental mechanism of the laser effect remains quite unclear. With our experiments we wa...

journal_title：Journal of biophotonics

authors： Hibst R,Graser R,Udart M,Stock K

更新日期：2010-06-01 00:00:00

abstract：:Stimulated Raman scattering (SRS) has been applied to unstained samples of articular cartilage enabling the investigation of living cells within fresh tissue. Hyperspectral SRS measurements over the CH vibrational region showed variations in protein and lipid content within the cells, pericellular matrix and interterr...

journal_title：Journal of biophotonics

authors： Mansfield J,Moger J,Green E,Moger C,Winlove CP

更新日期：2013-10-01 00:00:00

abstract：:Stimulated Raman scattering (SRS) microscopy is a label-free method generating images based on chemical contrast within samples, and has already shown its great potential for high-sensitivity and fast imaging of biological specimens. The capability of SRS to collect molecular vibrational signatures in bio-samples, cou...

journal_title：Journal of biophotonics

authors： Laptenok SP,Rajamanickam VP,Genchi L,Monfort T,Lee Y,Patel II,Bertoncini A,Liberale C

更新日期：2019-09-01 00:00:00

abstract：:Acridine orange (AO) staining is used to diagnose DNA fragmentation status in sperm cells. Interferometric phase microscopy (IPM) is an optical imaging method based on digital holographic microscopy that provides quantitative morphological and refractive index imaging of cells in vitro without the need for staining. W...

journal_title：Journal of biophotonics

authors： Barnea I,Karako L,Mirsky SK,Levi M,Balberg M,Shaked NT

更新日期：2018-11-01 00:00:00

abstract：:In vivo visualization of the human lymphatic system is limited by the mode of delivery of tracing agents, depth of field and size of the area examined, and specificity of the cell markers used to distinguish lymphatic endothelium from the blood vessels and the surrounding tissues. These limitations are particularly pr...

journal_title：Journal of biophotonics

authors： Lokmic Z

更新日期：2018-08-01 00:00:00

abstract：:5-aminolevulinic acid (ALA) and its methylated ester (MAL) are the most common topical agents used in photodynamic therapy (PDT) as precursors of the photosensitizer protoporphyrin IX (PpIX). The induction of newly PpIX depends on incubation time of each photosensitizer in the tissue and the presence of high intralesi...

journal_title：Journal of biophotonics

authors： Lima CA,Goulart VP,Bechara EJ,Correa L,Zezell DM

更新日期：2016-12-01 00:00:00

abstract：:Limb perfusion monitoring is critical for diabetes mellitus (DM) patients as they are vulnerable to vascular complications due to prolonged hyperglycemia. However, current clinical approaches are ineffective in vascular imaging and in assessing vascular function in lower limbs. In this work, a concave ultrasound trans...

journal_title：Journal of biophotonics

authors： Yang J,Zhang G,Shang Q,Wu M,Huang L,Jiang H

更新日期：2020-08-01 00:00:00

abstract：:There has been increasing use of in vitro cell culture models that more realistically replicate the three-dimensional (3D) environment found in vivo. Multicellular tumor spheroids (MTS) using cell lines or patient-derived organoids have become an important in vitro drug development tool, where cells are grown in a 3D ...

journal_title：Journal of biophotonics

authors： Jamieson LE,Harrison DJ,Campbell CJ

更新日期：2019-05-01 00:00:00

abstract：:Solar radiation exposure is recognised to be a significant contributor to the development of skin cancer. Monitoring the simultaneous and consecutive mechanisms of interaction could provide a greater understanding of the process of photocarcinogenesis. This work presents an analysis of the biochemical and morphologica...

journal_title：Journal of biophotonics

authors： Lopez-Gonzalez U,Casey A,J Byrne H

更新日期：2020-10-24 00:00:00

abstract：:The use of conventional fluorescence microscopy for characterizing tissue pathological states is limited by overlapping spectra and the dependence on excitation power and fluorophore concentration. Fluorescence lifetime imaging microscopy (FLIM) can overcome these limitations due to its insensitivity to fluorophore co...

journal_title：Journal of biophotonics

authors： Gu J,Fu CY,Ng BK,Gulam Razul Ss,Lim SK

更新日期：2014-07-01 00:00:00

abstract：:The purpose of this study was to evaluate the tomographic features of postrefractive surgery eyes. This was a retrospective evaluation of clinical data. Three patients with post-LASIK (laser-assisted in situ keratomileusis) and two patients with post-SMILE (small incision lenticule extraction) ectasia were imaged with...

journal_title：Journal of biophotonics

authors： Khamar P,Dalal R,Chandapura R,Francis M,Shetty R,Nelson EJR,Nuijts RMMA,Sinha Roy A

更新日期：2019-02-01 00:00:00

abstract：:The research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using 'Laser Induced Breakdown Spectroscopy' (LIBS) on the plasma plume created during laser tissue ablation. The background of this study is to establish a real time feedback ...

journal_title：Journal of biophotonics

authors： Kanawade R,Mahari F,Klämpfl F,Rohde M,Knipfer C,Tangermann-Gerk K,Adler W,Schmidt M,Stelzle F

更新日期：2015-01-01 00:00:00