Microfluidics and photonics for Bio-System-on-a-Chip: a review of advancements in technology towards a microfluidic flow cytometry chip.

abstract：:Cardiomyocytes derived from human pluripotent stem cells are a promising tool for disease modeling, drug compound testing, and cardiac toxicity screening. Bio-image segmentation is a prerequisite step in cardiomyocyte image analysis by digital holography (DH) in microscopic configuration and has provided satisfactory ...

journal_title：Journal of biophotonics

authors： Moon I,Jaferzadeh K,Ahmadzadeh E,Javidi B

更新日期：2018-12-01 00:00:00

abstract：:Low-power laser irradiation (LPLI) has been extensively employed to modulate inflammation in vitro and in vivo. Previous reports from our group indicated that LPLI might regulate glycemia in diabetic animals. Diabetes results in chronic hyperglycemia and therefore chronic inflammation by upregulation of inflammatory m...

journal_title：Journal of biophotonics

authors： Fukuoka CY,Torres Schröter G,Nicolau J,Simões A

更新日期：2016-12-01 00:00:00

abstract：:The aim of this study is to identify changes in scattering with optical coherence tomography (OCT) and relate these measurements with mitochondrial changes during the initiation of apoptosis. Human retinal pigment epithelial cells were cultured and apoptosis was induced using 10% alcohol. Using the attenuation coeffic...

journal_title：Journal of biophotonics

authors： de Bruin DM,Broekgaarden M,van Gemert MJ,Heger M,de la Rosette JJ,Van Leeuwen TG,Faber DJ

更新日期：2016-09-01 00:00:00

abstract：:Alveolar type II (ATII) cells in the peripheral human lung spontaneously differentiate toward ATI cells, thus enabling air-blood barrier formation. Here, linear Raman and coherent anti-Stokes Raman scattering (CARS) microscopy are applied to study cell differentiation of freshly isolated ATII cells. The Raman spectra ...

journal_title：Journal of biophotonics

authors： Vukosavljevic B,Hittinger M,Hachmeister H,Pilger C,Murgia X,Gepp MM,Gentile L,Huwer H,Schneider-Daum N,Huser T,Lehr CM,Windbergs M

更新日期：2019-06-01 00:00:00

abstract：:We present a pseudo-real-time retinal layer segmentation for high-resolution Sensorless Adaptive Optics-Optical Coherence Tomography (SAO-OCT). Our pseudo-real-time segmentation method is based on Dijkstra's algorithm that uses the intensity of pixels and the vertical gradient of the image to find the minimum cost in ...

journal_title：Journal of biophotonics

authors： Janpongsri W,Huang J,Ng R,Wahl DJ,Sarunic MV,Jian Y

更新日期：2020-08-01 00:00:00

abstract：:We report on transient membrane perforation of living cancer cells using plasmonic gold nanoparticles (AuNPs) enhanced single near infrared (NIR) femtosecond (fs) laser pulse. Under optimized laser energy fluence, single pulse treatment (τ = 45 fs, λ = 800 nm) resulted in 77% cell perforation efficiency and 90% cell v...

journal_title：Journal of biophotonics

authors： Boutopoulos C,Bergeron E,Meunier M

更新日期：2016-01-01 00:00:00

abstract：:Light delivery and monitoring during photodynamic therapy (PDT) is often limited by the need for a physical link between the light source, detectors and the treatment volume. This paper reports on the first in vivo experiments performed with a fully implantable telemetric system, designed for a rat glioblastoma model....

journal_title：Journal of biophotonics

authors： van Zaane F,Subbaiyan D,van der Ploeg-van den Heuvel A,de Bruijn HS,Balbas EM,Pandraud G,Sterenborg HJ,French PJ,Robinson DJ

更新日期：2010-06-01 00:00:00

abstract：:There has been increasing use of in vitro cell culture models that more realistically replicate the three-dimensional (3D) environment found in vivo. Multicellular tumor spheroids (MTS) using cell lines or patient-derived organoids have become an important in vitro drug development tool, where cells are grown in a 3D ...

journal_title：Journal of biophotonics

authors： Jamieson LE,Harrison DJ,Campbell CJ

更新日期：2019-05-01 00:00:00

abstract：:Osteoporosis is a major public health problem worldwide. Here, we present a quantitative multispectral photoacoustic method for the evaluation of bone pathologies which has significant advantages over pure ultrasonic or pure optical methods as it provides both molecular information and bone mechanical status. This is ...

journal_title：Journal of biophotonics

authors： Steinberg I,Turko N,Levi O,Gannot I,Eyal A

更新日期：2016-09-01 00:00:00

abstract：:The aim of this study was to evaluate whether OCT topography of the Bowman's layer and artificial intelligence (AI) can result in better diagnosis of forme fruste (FFKC) and clinical keratoconus (KC). Normal (n = 221), FFKC (n = 72) and KC (n = 116) corneas were included. Some of the FFKC and KC patients had the fello...

journal_title：Journal of biophotonics

authors： Chandapura R,Salomão MQ,Ambrósio R Jr,Swarup R,Shetty R,Sinha Roy A

更新日期：2019-10-01 00:00:00

abstract：:DsRed is representative of the tetrameric reef coral fluorescent proteins that constitute particularly interesting coupled multichromophoric systems. Either a green emitting or a red emitting chromophore can form within each of the monomers of the protein tetramer. Within the tetramers the chromophores are thought to ...

journal_title：Journal of biophotonics

authors： Blum C,Meixner AJ,Subramaniam V

更新日期：2011-01-01 00:00:00

abstract：:Microcalcifications are an early mammographic sign of breast cancer and a target for stereotactic breast needle biopsy. Here, we develop and compare different approaches for developing Raman classification algorithms to diagnose invasive and in situ breast cancer, fibrocystic change and fibroadenoma that can be associ...

journal_title：Journal of biophotonics

authors： Dingari NC,Barman I,Saha A,McGee S,Galindo LH,Liu W,Plecha D,Klein N,Dasari RR,Fitzmaurice M

更新日期：2013-04-01 00:00:00

abstract：:Fluctuations in brain water content has attracted increasing interest, particularly as regards studies of the glymphatic system, which is connected with the complex organization of dural lymphatic vessels, responsible for cleaning tissue. Disturbances of glymphatic circulation are associated with several brain disorde...

journal_title：Journal of biophotonics

authors： Myllylä T,Harju M,Korhonen V,Bykov A,Kiviniemi V,Meglinski I

更新日期：2018-08-01 00:00:00

abstract：:Intravascular optical coherence tomography (IV-OCT) is a light-based imaging modality with high resolution, which employs near-infrared light to provide tomographic intracoronary images. Morbidity caused by coronary heart disease is a substantial cause of acute coronary syndrome and sudden cardiac death. The most comm...

journal_title：Journal of biophotonics

authors： Abdolmanafi A,Cheriet F,Duong L,Ibrahim R,Dahdah N

更新日期：2020-01-01 00:00:00

abstract：:The authors have developed a tomographic diffractive microscope that combines microholography with illumination from an angular synthetic aperture. It images specimens relative to their complex index of refraction distribution (index and absorption) and permits imaging of unlabelled specimens, with high lateral resolu...

journal_title：Journal of biophotonics

authors： Simon B,Debailleul M,Beghin A,Tourneur Y,Haeberlé O

更新日期：2010-07-01 00:00:00

abstract：:Delay-and-sum (DAS) is one of the most common algorithms used to construct the photoacoustic images due to its low complexity. However, it results in images with high sidelobes and low resolution. Delay-and-standard-deviation (DASD) weighting factor can improve the contrast of the images compared to DAS. However, it s...

journal_title：Journal of biophotonics

authors： Paridar R,Mozaffarzadeh M,Periyasamy V,Basij M,Mehrmohammadi M,Pramanik M,Orooji M

更新日期：2019-06-01 00:00:00

abstract：:Quantification of the mucosa oxygenation levels during Endoscopic imaging provides useful physiological/diagnostic information. In this work a method for non-contact quantification of the oxygen saturation index during Endoscopic imaging using three discrete spectral-band in the blue, the green, and the red parts of t...

journal_title：Journal of biophotonics

authors： Fawzy Y

更新日期：2009-12-01 00:00:00

abstract：:Surface-enhanced Raman scattering (SERS) spectroscopy possesses the most promising advantage of multiplex detection for biosensing applications, which is achieved due to the narrow 'fingerprint' Raman spectra from the analyte molecules. We developed an ultrasensitive platform for the multiplex detection of cancer biom...

journal_title：Journal of biophotonics

authors： Dinish US,Balasundaram G,Chang YT,Olivo M

更新日期：2014-11-01 00:00:00

abstract：:An experimental study of the influence of the conformational change suffered by molecular beacon (MB) probes-upon the biorecognition of nucleic acid target oligonucleotides over evanescent wave photonic sensors-is reported. To this end, high sensitivity photonic sensors based on silicon photonic bandgap (PBG) structur...

journal_title：Journal of biophotonics

authors： Ruiz-Tórtola Á,Prats-Quílez F,González-Lucas D,Bañuls MJ,Maquieira Á,Wheeler G,Dalmay T,Griol A,Hurtado J,Bohlmann H,Götzen R,García-Rupérez J

更新日期：2018-10-01 00:00:00

abstract：:Semiconductor nanoparticles (NPs) became important and wide-used tool for cell imaging because of their unique remarkable properties. Nevertheless, all previous investigations in this area were done on proliferating cells. For the first time, this work demonstrates strong influence of cell active proliferation/contact...

journal_title：Journal of biophotonics

authors： Serdiuk T,Lysenko V,Mognetti B,Skryshevsky V,Géloën A

更新日期：2013-03-01 00:00:00

abstract：:Articular cartilage posesses unique material properties due to a complex depth-dependent composition of sub-components. Raman spectroscopy has proven valuable in quantifying this composition through cartilage cross-sections. However, cross-sectioning requires tissue destruction and is not practical in situ. In this wo...

journal_title：Journal of biophotonics

authors： Mason D,Murugkar S,Speirs AD

更新日期：2021-01-01 00:00:00

abstract：:We present a novel silicon photonic biosensor using phase-shifted Bragg gratings in a slot waveguide. The optical field is concentrated inside the slot region, leading to efficient light-matter interaction. The Bragg gratings are formed with sidewall corrugations on the outside of the waveguide, and a phase shift is i...

journal_title：Journal of biophotonics

authors： Wang X,Flueckiger J,Schmidt S,Grist S,Fard ST,Kirk J,Doerfler M,Cheung KC,Ratner DM,Chrostowski L

更新日期：2013-10-01 00:00:00

abstract：:Optical spectroscopy of a single gold nanoparticle, functionalized with an aptamer, is used to sense the specific binding of avidin. Herewith, the field of single noble metal nanoparticle biosensors is extended to the important field of aptamer based assays. The sensitivity of this initial, but not yet optimized apta-...

journal_title：Journal of biophotonics

authors： Hernandez FJ,Dondapati SK,Ozalp VC,Pinto A,O'Sullivan CK,Klar TA,Katakis I

更新日期：2009-04-01 00:00:00

abstract：:Low-level laser therapy (LLLT) is known to enhance mitochondrial electron transfer and ATP production; thus, this study asked whether LLLT could stimulate the oxidative burst in human neutrophils (PMN) and improve their ability to kill microorganisms. Blood from healthy human subjects was collected and PMN were isolat...

journal_title：Journal of biophotonics

authors： Cerdeira CD,Lima Brigagão MR,Carli ML,de Souza Ferreira C,de Oliveira Isac Moraes G,Hadad H,Costa Hanemann JA,Hamblin MR,Sperandio FF

更新日期：2016-12-01 00:00:00

abstract：:FTIR spectroscopy is a powerful diagnostic tool that can also derive biochemical signatures of a wide range of cellular materials, such as cytology, histology, live cells, and biofluids. However, while classification is a well-established subject, biomarker identification lacks standards and validation of its methods....

journal_title：Journal of biophotonics

authors： Trevisan J,Park J,Angelov PP,Ahmadzai AA,Gajjar K,Scott AD,Carmichael PL,Martin FL

更新日期：2014-04-01 00:00:00

abstract：:The broad range of applications of spatially-offset Raman spectroscopy (SORS) were found to involve samples having only marginal differences in Raman cross-sections between the surface and subsurface targets. We report the results of a feasibility study to evaluate the potential of the approach to identify the presenc...

journal_title：Journal of biophotonics

authors： Khan KM,Dutta SB,Krishna H,Majumder SK

更新日期：2016-09-01 00:00:00

abstract：:5-aminolevulinic acid (ALA) and its methylated ester (MAL) are the most common topical agents used in photodynamic therapy (PDT) as precursors of the photosensitizer protoporphyrin IX (PpIX). The induction of newly PpIX depends on incubation time of each photosensitizer in the tissue and the presence of high intralesi...

journal_title：Journal of biophotonics

authors： Lima CA,Goulart VP,Bechara EJ,Correa L,Zezell DM

更新日期：2016-12-01 00:00:00

abstract：:Skin optical clearing has shown tremendous potential in improving various optical imaging performances, but there is some certain blindness in screening out high-efficiency in vivo optical clearing methods. In this work, three optical clearing agents: sucrose (Suc), fructose (Fruc) and PEG-400 (PEG), and two chemical ...

journal_title：Journal of biophotonics

authors： Shi R,Guo L,Zhang C,Feng W,Li P,Ding Z,Zhu D

更新日期：2017-06-01 00:00:00

abstract：:Intraoperative detection of residual malignant cells at tumor margins following excision of primary tumors could help improving surgery and thus patients' outcome. The feasibility of the tumor antigens epidermal growth factor receptor (EGF-R) and epithelial cell adhesion molecule (EpCAM) for antibody-dependent confoca...

journal_title：Journal of biophotonics

authors： Englhard AS,Palaras A,Volgger V,Stepp H,Mack B,Libl D,Gires O,Betz CS

更新日期：2017-10-01 00:00:00

abstract：:A multiple exposure laser speckle contrast imaging (MELSCI) setup for visualizing blood perfusion was developed using a field programmable gate array (FPGA), connected to a 1000 frames per second (fps) 1-megapixel camera sensor. Multiple exposure time images at 1, 2, 4, 8, 16, 32 and 64 milliseconds were calculated by...

journal_title：Journal of biophotonics

authors： Hultman M,Fredriksson I,Larsson M,Alvandpour A,Strömberg T

更新日期：2018-02-01 00:00:00