Cell perforation mediated by plasmonic bubbles generated by a single near infrared femtosecond laser pulse.

abstract：:The purpose of this study was to evaluate thermal and near-infrared (NIR) reflectance imaging methods for the assessment of the activity of root caries lesions. In addition, changes in the lesion structure were monitored with polarization sensitive optical coherence tomography (PS-OCT). Artificial bovine and natural r...

journal_title：Journal of biophotonics

authors： Lee RC,Darling CL,Staninec M,Ragadio A,Fried D

更新日期：2017-03-01 00:00:00

abstract：:To this day, any photosensitizers for the photodynamic treatment of pulmonary illnesses have been administered intravenously. There is, however, an intrinsic difficulty in reaching the target cells or bacteria in the respiratory system. Nebulization could overcome distribution problems and alleviate side effects by de...

journal_title：Journal of biophotonics

authors： Kassab G,Geralde MC,Inada NM,Achiles AE,Guerra VG,Bagnato VS

更新日期：2019-04-01 00:00:00

abstract：:Infrared spectra obtained from cell or tissue specimen have commonly been observed to involve a significant degree of scattering effects, often Mie scattering, which probably overshadows biochemically relevant spectral information by a nonlinear, nonadditive spectral component in Fourier transform infrared (FTIR) spec...

journal_title：Journal of biophotonics

authors： Raulf AP,Butke J,Menzen L,Küpper C,Großerueschkamp F,Gerwert K,Mosig A

更新日期：2020-12-08 00:00:00

abstract：:Semiconductor nanoparticles (NPs) became important and wide-used tool for cell imaging because of their unique remarkable properties. Nevertheless, all previous investigations in this area were done on proliferating cells. For the first time, this work demonstrates strong influence of cell active proliferation/contact...

journal_title：Journal of biophotonics

authors： Serdiuk T,Lysenko V,Mognetti B,Skryshevsky V,Géloën A

更新日期：2013-03-01 00:00:00

abstract：:Localization microscopy methods like Stochastic Optical Reconstruction Microscopy (STORM) are very well suited for exploring clustering of proteins, as the data inherently provide a list of molecular coordinates. Here we use state-of-art cluster analysis algorithms (DBSCAN) to explore the clustering behaviour of diffe...

journal_title：Journal of biophotonics

authors： Persson H,Potrzebowski W,Potrzebowska K,Svensson LM

更新日期：2019-03-01 00:00:00

abstract：:Microfluidics and photonics come together to form a field commonly referred to as 'optofluidics'. Flow cytometry provides the field with a technology base from which both microfluidic and photonic components be developed and integrated into a useful device. This article reviews some of the more recent developments to ...

journal_title：Journal of biophotonics

authors： Godin J,Chen CH,Cho SH,Qiao W,Tsai F,Lo YH

更新日期：2008-10-01 00:00:00

abstract：:An integrated multimodal optical microscope is demonstrated for high-resolution, structural and functional imaging of engineered and natural skin. This microscope incorporates multiple imaging modalities including optical coherence (OCM), multi-photon (MPM), and fluorescence lifetime imaging microscopy (FLIM), enablin...

journal_title：Journal of biophotonics

authors： Zhao Y,Graf BW,Chaney EJ,Mahmassani Z,Antoniadou E,Devolder R,Kong H,Boppart MD,Boppart SA

更新日期：2012-05-01 00:00:00

abstract：:Total internal reflection fluorescence excitation (TIRF) microscopy allows the selective observation of fluorescent molecules in immediate proximity to an interface between different refractive indices. Objective-type or prism-less TIRF excitation is typically achieved with laser light sources. We here propose a simpl...

journal_title：Journal of biophotonics

authors： Kogel A,Kalwa H,Urban N,Schaefer M

更新日期：2019-11-01 00:00:00

abstract：:The authors have developed a tomographic diffractive microscope that combines microholography with illumination from an angular synthetic aperture. It images specimens relative to their complex index of refraction distribution (index and absorption) and permits imaging of unlabelled specimens, with high lateral resolu...

journal_title：Journal of biophotonics

authors： Simon B,Debailleul M,Beghin A,Tourneur Y,Haeberlé O

更新日期：2010-07-01 00:00:00

abstract：:The structural organization of cellular membranes has an essential influence on their functionality. The membrane surfaces currently are considered to consist of various distinct patches, which play an important role in many processes, however, not all parameters such as size and distribution are fully determined. In ...

journal_title：Journal of biophotonics

authors： Deckert-Gaudig T,Böhme R,Freier E,Sebesta A,Merkendorf T,Popp J,Gerwert K,Deckert V

更新日期：2012-07-01 00:00:00

abstract：:Currently, optical coherence tomography (OCT), is not capable of obtaining molecular information often crucial for identification of disease. To enable molecular imaging with OCT, we have further developed a technique that harnesses transient changes in light absorption in the sample to garner molecular information. A...

journal_title：Journal of biophotonics

authors： Carrasco-Zevallos O,Shelton RL,Kim W,Pearson J,Applegate BE

更新日期：2015-01-01 00:00:00

abstract：:Acridine orange (AO) staining is used to diagnose DNA fragmentation status in sperm cells. Interferometric phase microscopy (IPM) is an optical imaging method based on digital holographic microscopy that provides quantitative morphological and refractive index imaging of cells in vitro without the need for staining. W...

journal_title：Journal of biophotonics

authors： Barnea I,Karako L,Mirsky SK,Levi M,Balberg M,Shaked NT

更新日期：2018-11-01 00:00:00

abstract：:Perfusion and oxygenation are critical parameters of muscle metabolism in health and disease. They have been both the target of many studies, in particular using near-infrared spectroscopy (NIRS). However, difficulties with quantifying NIRS signals have limited a wide dissemination of the method to the clinics. Our ai...

journal_title：Journal of biophotonics

authors： Karlas A,Kallmayer M,Fasoula NA,Liapis E,Bariotakis M,Krönke M,Anastasopoulou M,Reber J,Eckstein HH,Ntziachristos V

更新日期：2020-06-01 00:00:00

abstract：:In vivo visualization of the human lymphatic system is limited by the mode of delivery of tracing agents, depth of field and size of the area examined, and specificity of the cell markers used to distinguish lymphatic endothelium from the blood vessels and the surrounding tissues. These limitations are particularly pr...

journal_title：Journal of biophotonics

authors： Lokmic Z

更新日期：2018-08-01 00:00:00

abstract：:Low-level laser therapy (LLLT) is known to enhance mitochondrial electron transfer and ATP production; thus, this study asked whether LLLT could stimulate the oxidative burst in human neutrophils (PMN) and improve their ability to kill microorganisms. Blood from healthy human subjects was collected and PMN were isolat...

journal_title：Journal of biophotonics

authors： Cerdeira CD,Lima Brigagão MR,Carli ML,de Souza Ferreira C,de Oliveira Isac Moraes G,Hadad H,Costa Hanemann JA,Hamblin MR,Sperandio FF

更新日期：2016-12-01 00:00:00

abstract：:The fluorescence lifetime of nicotinamide adenine dinucleotide (NADH) is commonly used in conjunction with the phasor approach as a molecular biomarker to provide information on cellular metabolism of autofluorescence imaging of cells and tissue. However, in the phasor approach, the bound and free lifetime defining th...

journal_title：Journal of biophotonics

authors： Ranjit S,Malacrida L,Stakic M,Gratton E

更新日期：2019-11-01 00:00:00

abstract：:Optical coherence elastography (OCE) represents the frontier of optical elasticity imaging techniques and focuses on the micro-scale assessment of tissue biomechanics in 3D that is hard to achieve with traditional elastographic methods. Benefit from the advancement of optical coherence tomography, and driven by the in...

journal_title：Journal of biophotonics

authors： Wang S,Larin KV

更新日期：2015-04-01 00:00:00

abstract：:The photodetachment of Br(-), I(-) and OH(-) in aqueous solution is studied by 2- and 3-pulse femtosecond spectroscopy. The UV excitation leads to fast electron separation followed by formation of a donor-electron pairs. An additional repump pulse is used for secondary excitation of the intermediates. The 3-pulse tech...

journal_title：Journal of biophotonics

authors： Fischer MK,Gliserin A,Laubereau A,Iglev H

更新日期：2011-03-01 00:00:00

abstract：:A simple scheme for multimodal coherent anti-Stokes Raman scattering (CARS) microscopy is based on the spectral focusing of ultrafast-oscillator-derived pump/probe light and synchronous photonic crystal fiber (PCF) fiber-generated broadband Stokes light. To date, such schemes allowed rapid hyperspectral imaging throug...

journal_title：Journal of biophotonics

authors： Pegoraro AF,Slepkov AD,Ridsdale A,Moffatt DJ,Stolow A

更新日期：2014-01-01 00:00:00

abstract：:Tumor metastasis to lymph nodes is an important contributory factor for cancer-related deaths despite recent developments in cancer therapy. In this study, we demonstrate that tumor in the proper axillary lymph node (PALN) of the mouse can be treated by the application of external laser light to trigger the unloading ...

journal_title：Journal of biophotonics

authors： Matsuki D,Adewale O,Horie S,Okajima J,Komiya A,Oluwafemi O,Maruyama S,Mori S,Kodama T

更新日期：2017-12-01 00:00:00

abstract：:We present a pseudo-real-time retinal layer segmentation for high-resolution Sensorless Adaptive Optics-Optical Coherence Tomography (SAO-OCT). Our pseudo-real-time segmentation method is based on Dijkstra's algorithm that uses the intensity of pixels and the vertical gradient of the image to find the minimum cost in ...

journal_title：Journal of biophotonics

authors： Janpongsri W,Huang J,Ng R,Wahl DJ,Sarunic MV,Jian Y

更新日期：2020-08-01 00:00:00

abstract：:The aim of this work was to assess the antimicrobial efficacy on Pseudomonas aeruginosa of nanomicelles loaded with curcumin (CUR) alone and activated by blue laser light in an antimicrobial photodynamic therapy (APDT) approach. First, free CUR in liquid suspension and loaded in three amphiphilic nanomicelles (CUR-DAP...

journal_title：Journal of biophotonics

authors： Rupel K,Zupin L,Brich S,Mardirossian M,Ottaviani G,Gobbo M,Di Lenarda R,Pricl S,Crovella S,Zacchigna S,Biasotto M

更新日期：2020-11-05 00:00:00

abstract：:In biomedical applications, nanoparticles have demonstrated the potential to eradicate abnormal cells in small localized pathological zones associated with cancer or infections. Here, we introduce a method for nanotechnology-based photothermal (PT) killing of whole organisms considered harmful to humans or the environ...

journal_title：Journal of biophotonics

authors： Foster SR,Galanzha EI,Totten DC,Beneš H,Shmookler Reis RJ,Zharov VP

更新日期：2014-07-01 00:00:00

abstract：:The dynamic properties of subcellular organism are important biomarkers of the health. Imaging subcellular level dynamics provides effective solutions for evaluating cell metabolism and testing the responses of cells to pathogens and drugs in pharmaceutical engineering. In this paper, we demonstrate an innovative appr...

journal_title：Journal of biophotonics

authors： Wei W,Tang P,Xie Z,Li Y,Wang RK

更新日期：2019-10-01 00:00:00

abstract：:Photodynamic therapy (PDT) uses photosensitizers and visible light in combination with molecular oxygen to produce reactive oxygen species (ROS) that kill malignant cells by apoptosis and/or necrosis, shut down the tumor microvasculature and stimulate the host immune system. The excited singlet state of oxygen (1 O2 )...

journal_title：Journal of biophotonics

authors： Li B,Lin L,Lin H,Wilson BC

更新日期：2016-12-01 00:00:00

abstract：:The sun protection factor (SPF) values are currently determined using an invasive procedure, in which the volunteers are irradiated with ultraviolet (UV) light. Non-invasive approaches based on hybrid diffuse reflectance spectroscopy (HDRS) have shown a good correlation with conventional SPF testing. Here, we present ...

journal_title：Journal of biophotonics

authors： Throm CM,Wiora G,Reble C,Schleusener J,Schanzer S,Karrer H,Kolbe L,Khazaka G,Meinke MC,Lademann J

更新日期：2020-10-06 00:00:00

abstract：:There has been increasing use of in vitro cell culture models that more realistically replicate the three-dimensional (3D) environment found in vivo. Multicellular tumor spheroids (MTS) using cell lines or patient-derived organoids have become an important in vitro drug development tool, where cells are grown in a 3D ...

journal_title：Journal of biophotonics

authors： Jamieson LE,Harrison DJ,Campbell CJ

更新日期：2019-05-01 00:00:00

abstract：:Conventional histopathology is rapidly shifting towards digital integration. Will microscopes (and pathologists) soon be obsolete? Or are we dealing with just another image modality that leaves the core of tissue diagnosis intact? This article provides an overview of current digital pathology applications and research...

journal_title：Journal of biophotonics

authors： Brachtel E,Yagi Y

更新日期：2012-04-01 00:00:00

abstract：:Osteoporosis is a major public health problem worldwide. Here, we present a quantitative multispectral photoacoustic method for the evaluation of bone pathologies which has significant advantages over pure ultrasonic or pure optical methods as it provides both molecular information and bone mechanical status. This is ...

journal_title：Journal of biophotonics

authors： Steinberg I,Turko N,Levi O,Gannot I,Eyal A

更新日期：2016-09-01 00:00:00

abstract：:A Monte Carlo simulation was adapted to specify a skin model with pigmented epidermis, dermis with low baseline blood content, and vessels of a vascular lesion with an average added blood volume fraction of 5%. In the study, the lesion vessel diameters were increased and the number of lesion vessels decreased, such th...

journal_title：Journal of biophotonics

authors： Jacques SL

更新日期：2010-01-01 00:00:00