Abstract:
:Conventional histopathology is rapidly shifting towards digital integration. Will microscopes (and pathologists) soon be obsolete? Or are we dealing with just another image modality that leaves the core of tissue diagnosis intact? This article provides an overview of current digital pathology applications and research with emphasis on whole slide imaging (WSI). Static or interactive digital pathology work stations already can be used for many purposes, e.g. telepathology expert consultations, frozen section diagnosis in remote areas, cytology screening, quality assurance, diagnostic validations for clinical trials, quantitation of hormone receptor or HER2 studies in breast cancer, or three-dimensional visualization of anatomical structures, among others. Changes of workflow in histology laboratories are beginning to enable digital image acquisition and WSI in a routine setting. WSI plays an increasing role in pathology education, glass slide boxes in medical schools are being replaced by digital slide collections; digital slide seminars and virtual microscopy are used for postgraduate and continuing medical education in pathology. Research and efforts to validate WSI systems for diagnostic settings are ongoing.
journal_name
J Biophotonicsjournal_title
Journal of biophotonicsauthors
Brachtel E,Yagi Ydoi
10.1002/jbio.201100103subject
Has Abstractpub_date
2012-04-01 00:00:00pages
327-35issue
4eissn
1864-063Xissn
1864-0648journal_volume
5pub_type
杂志文章,评审abstract::The aim of this study is to identify changes in scattering with optical coherence tomography (OCT) and relate these measurements with mitochondrial changes during the initiation of apoptosis. Human retinal pigment epithelial cells were cultured and apoptosis was induced using 10% alcohol. Using the attenuation coeffic...
journal_title:Journal of biophotonics
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journal_title:Journal of biophotonics
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journal_title:Journal of biophotonics
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journal_title:Journal of biophotonics
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journal_title:Journal of biophotonics
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pub_type: 杂志文章,撤回出版物
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