siRNA release from gold nanoparticles by nanosecond pulsed laser irradiation and analysis of the involved temperature increase.

abstract：:Three-dimensional reconstruction of tissue structures is essential for biomedical research. The development of light microscopes and various fluorescent labeling techniques provides powerful tools for this motivation. However, optical imaging depth suffers from strong light scattering due to inherent heterogeneity of ...

journal_title：Journal of biophotonics

authors： Yu T,Qi Y,Gong H,Luo Q,Zhu D

更新日期：2018-02-01 00:00:00

abstract：:Conventional histopathology is rapidly shifting towards digital integration. Will microscopes (and pathologists) soon be obsolete? Or are we dealing with just another image modality that leaves the core of tissue diagnosis intact? This article provides an overview of current digital pathology applications and research...

journal_title：Journal of biophotonics

authors： Brachtel E,Yagi Y

更新日期：2012-04-01 00:00:00

abstract：:Clinicians need a way to rapidly and reliably test the correct functioning of near-infrared spectroscopy (NIRS)-based oximeters. Therefore, optical phantoms for quality assessment of NIRS oximeters are needed. The fabrication of such phantoms that mimic the optical properties of biological tissue in the NIR range repr...

journal_title：Journal of biophotonics

authors： Tomm N,Ahnen L,Isler H,Kleiser S,Karen T,Ostojic D,Wolf M,Scholkmann F

更新日期：2019-04-01 00:00:00

abstract：:Photobiomodulation (PBM) therapy has been noted to promote cell proliferation and growth in many different cell types shown both in vitro and in vivo. Currently, treatment regimens are used in the clinic for a variety of ailments, including wound healing. However, most protocols treat an anatomical site without consid...

journal_title：Journal of biophotonics

authors： Engel KW,Khan I,Arany PR

更新日期：2016-12-01 00:00:00

abstract：:We investigate the optical wavelength dependence in quantitative photoacoustic (QPA) assessment of red blood cell (RBC) aggregation and oxygen saturation (sO2 ) during pulsatile blood flow. Experimentally, the pulsatile flow was imaged with a 700 to 900 nm laser using the VevoLAZR. Theoretically, the photoacoustic (PA...

journal_title：Journal of biophotonics

authors： Bok TH,Hysi E,Kolios MC

更新日期：2018-08-01 00:00:00

abstract：:The photodetachment of Br(-), I(-) and OH(-) in aqueous solution is studied by 2- and 3-pulse femtosecond spectroscopy. The UV excitation leads to fast electron separation followed by formation of a donor-electron pairs. An additional repump pulse is used for secondary excitation of the intermediates. The 3-pulse tech...

journal_title：Journal of biophotonics

authors： Fischer MK,Gliserin A,Laubereau A,Iglev H

更新日期：2011-03-01 00:00:00

abstract：:Single-molecule localisation based super-resolution fluorescence imaging produces maps of the coordinates of fluorescent molecules in a region of interest. Cluster analysis algorithms provide information concerning the clustering characteristics of these molecules, often through the generation of cluster heat maps bas...

journal_title：Journal of biophotonics

authors： Griffié J,Boelen L,Burn G,Cope AP,Owen DM

更新日期：2015-11-01 00:00:00

abstract：:Retinoblastoma (RB) is a rare form of cancer of the retina most prevalent in young children. We successfully show that laser-induced cell disruption, mediated by gold plasmonic nanoparticle (NP), is a potential and efficient therapy to kill the cancerous cells. The proof of concept is demonstrated in vitro on cultured...

journal_title：Journal of biophotonics

authors： Darviot C,Hardy P,Meunier M

更新日期：2019-11-01 00:00:00

abstract：:Photodynamic therapy (PDT) uses photosensitizers and visible light in combination with molecular oxygen to produce reactive oxygen species (ROS) that kill malignant cells by apoptosis and/or necrosis, shut down the tumor microvasculature and stimulate the host immune system. The excited singlet state of oxygen (1 O2 )...

journal_title：Journal of biophotonics

authors： Li B,Lin L,Lin H,Wilson BC

更新日期：2016-12-01 00:00:00

abstract：:Delay-and-sum (DAS) is one of the most common algorithms used to construct the photoacoustic images due to its low complexity. However, it results in images with high sidelobes and low resolution. Delay-and-standard-deviation (DASD) weighting factor can improve the contrast of the images compared to DAS. However, it s...

journal_title：Journal of biophotonics

authors： Paridar R,Mozaffarzadeh M,Periyasamy V,Basij M,Mehrmohammadi M,Pramanik M,Orooji M

更新日期：2019-06-01 00:00:00

abstract：:In this work we present how to entirely remove the scattering ambiguity present in existing multiphoton multifocal systems. This is achieved through the development and implementation of single-element detection systems that incorporate high-speed photon-counting electronics. These systems can be used to image entire ...

journal_title：Journal of biophotonics

authors： Hoover EE,Field JJ,Winters DG,Young MD,Chandler EV,Speirs JC,Lapenna JT,Kim SM,Ding SY,Bartels RA,Wang JW,Squier JA

更新日期：2012-05-01 00:00:00

abstract：:A new optical scattering contrast-agent based on polymer-nanoparticle encapsulated silver nanoplates (PESNs) is presented. Silver nanoplates were chosen due to the flexibility of tuning their plasmon frequencies. The polymer coating preserves their physical and optical properties and confers other advantages such as c...

journal_title：Journal of biophotonics

authors： Ray A,Kopelman R,Chon B,Briggman K,Hwang J

更新日期：2016-07-01 00:00:00

abstract：:Micro-/nanosphere-mediated femtosecond laser cell perforation is one of the high throughput technologies used for macro-molecule-delivery into multiple cells. We have demonstrated the delivery of plasmid-DNA/liposome complexes into cells using biodegradable polymer microspheres and a femtosecond laser and investigated...

journal_title：Journal of biophotonics

authors： Ishii A,Hiruta Y,Heinemann D,Heisterkamp A,Kanazawa H,Terakawa M

更新日期：2017-12-01 00:00:00

abstract：:Several studies have demonstrated the potential of cross-polarization optical coherence tomography (CP-OCT) to quantify the severity of early caries lesions (tooth decay) on tooth surfaces. The purpose of this study is to show that 2D images of the lesion depth and the integrated reflectivity can be used to accurately...

journal_title：Journal of biophotonics

authors： Chan KH,Chan AC,Fried WA,Simon JC,Darling CL,Fried D

更新日期：2015-01-01 00:00:00

abstract：:In this paper we introduce a custom scanning near-field optical microscope (SNOM) that simultaneously collects reflection and transmission near-field images along with topography. This dual-optical SNOM uses a bent probe, which allows for axial reflection imaging, accurate surface scanning, and easy identification of ...

journal_title：Journal of biophotonics

authors： Kyle JR,Kyle MD,Raghavan R,Budak G,Ozkan CS,Ozkan M

更新日期：2011-03-01 00:00:00

abstract：:For a precise manipulation of particles and cells with laser light as well as for the understanding and the control of the underlying processes it is important to visualize and quantify the response of the specimens. Thus, we investigated if digital holographic microscopy (DHM) can be used in combination with microflu...

journal_title：Journal of biophotonics

authors： Kemper B,Langehanenberg P,Höink A,von Bally G,Wottowah F,Schinkinger S,Guck J,Käs J,Bredebusch I,Schnekenburger J,Schütze K

更新日期：2010-07-01 00:00:00

abstract：:FTIR microspectroscopy was applied for studying macromolecular changes in human serum samples from patients with healthy livers, and those diagnosed with liver cirrhosis or hepatocellular carcinoma (HCC). Our study demonstrated that the serum samples from HCC and cirrhotic patients could readily be discriminated from ...

journal_title：Journal of biophotonics

authors： Thumanu K,Sangrajrang S,Khuhaprema T,Kalalak A,Tanthanuch W,Pongpiachan S,Heraud P

更新日期：2014-04-01 00:00:00

abstract：:In vivo microscopy has recently become a gold standard in lung immunology studies involving small animals, largely benefiting from the democratization of multiphoton microscopy allowing for deep tissue imaging. This technology represents currently our only way of exploring the lungs and inferring what happens in human...

journal_title：Journal of biophotonics

authors： Fiole D,Tournier JN

更新日期：2016-09-01 00:00:00

abstract：:We present a pseudo-real-time retinal layer segmentation for high-resolution Sensorless Adaptive Optics-Optical Coherence Tomography (SAO-OCT). Our pseudo-real-time segmentation method is based on Dijkstra's algorithm that uses the intensity of pixels and the vertical gradient of the image to find the minimum cost in ...

journal_title：Journal of biophotonics

authors： Janpongsri W,Huang J,Ng R,Wahl DJ,Sarunic MV,Jian Y

更新日期：2020-08-01 00:00:00

abstract：:Optical spectroscopy of a single gold nanoparticle, functionalized with an aptamer, is used to sense the specific binding of avidin. Herewith, the field of single noble metal nanoparticle biosensors is extended to the important field of aptamer based assays. The sensitivity of this initial, but not yet optimized apta-...

journal_title：Journal of biophotonics

authors： Hernandez FJ,Dondapati SK,Ozalp VC,Pinto A,O'Sullivan CK,Klar TA,Katakis I

更新日期：2009-04-01 00:00:00

abstract：:Since stimulated emission depletion (STED) nanoscopy was invented in 1994, this technique has been widely used in the fields of biomedicine and materials science. According to the imaging principle of STED technology, increasing the power of the depletion laser within a certain threshold can improve the resolution. Ho...

journal_title：Journal of biophotonics

authors： Wang J,Wang L,Zhang J,Yang Z,Yan W,Qu J

更新日期：2020-12-13 00:00:00

abstract：:Bone-marrow (BM)-derived cells have been shown to be capable of aiding skin regeneration in vivo by differentiating into keratinocytes. However, the conditions under which this occurs are not fully understood. Characterizing innate mechanisms of skin regeneration by stem cells in vivo is important for the area of stem...

journal_title：Journal of biophotonics

authors： Graf BW,Bower AJ,Chaney EJ,Marjanovic M,Adie SG,De Lisio M,Valero MC,Boppart MD,Boppart SA

更新日期：2014-01-01 00:00:00

abstract：:The aim of this work was to assess the antimicrobial efficacy on Pseudomonas aeruginosa of nanomicelles loaded with curcumin (CUR) alone and activated by blue laser light in an antimicrobial photodynamic therapy (APDT) approach. First, free CUR in liquid suspension and loaded in three amphiphilic nanomicelles (CUR-DAP...

journal_title：Journal of biophotonics

authors： Rupel K,Zupin L,Brich S,Mardirossian M,Ottaviani G,Gobbo M,Di Lenarda R,Pricl S,Crovella S,Zacchigna S,Biasotto M

更新日期：2020-11-05 00:00:00

abstract：:Photodynamic inactivation of bacteria (PDIB) is considered a new approach for the struggle against multiresistant bacteria. To achieve a sufficient level of bacteria killing, the photosensitizer must attach to and/or penetrate the bacteria and generate a sufficiently high amount of singlet oxygen. To optimize PDIB, th...

journal_title：Journal of biophotonics

authors： Regensburger J,Maisch T,Felgenträger A,Santarelli F,Bäumler W

更新日期：2010-06-01 00:00:00

abstract：:There has been increasing use of in vitro cell culture models that more realistically replicate the three-dimensional (3D) environment found in vivo. Multicellular tumor spheroids (MTS) using cell lines or patient-derived organoids have become an important in vitro drug development tool, where cells are grown in a 3D ...

journal_title：Journal of biophotonics

authors： Jamieson LE,Harrison DJ,Campbell CJ

更新日期：2019-05-01 00:00:00

abstract：:The fluorescence lifetime of nicotinamide adenine dinucleotide (NADH) is commonly used in conjunction with the phasor approach as a molecular biomarker to provide information on cellular metabolism of autofluorescence imaging of cells and tissue. However, in the phasor approach, the bound and free lifetime defining th...

journal_title：Journal of biophotonics

authors： Ranjit S,Malacrida L,Stakic M,Gratton E

更新日期：2019-11-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a wide range of survival times. We aimed to explore prognostic factors related to short survival based on clinical features and plasma metabolic signatures using surface-enhanced Raman spectroscopy (SERS). One hundred and thirty-eight sporad...

journal_title：Journal of biophotonics

authors： Zhang QJ,Chen Y,Zou XH,Hu W,Lin XL,Feng SY,Chen F,Xu LQ,Chen WJ,Wang N

更新日期：2019-08-01 00:00:00

abstract：:Intravascular optical coherence tomography (IV-OCT) is a light-based imaging modality with high resolution, which employs near-infrared light to provide tomographic intracoronary images. Morbidity caused by coronary heart disease is a substantial cause of acute coronary syndrome and sudden cardiac death. The most comm...

journal_title：Journal of biophotonics

authors： Abdolmanafi A,Cheriet F,Duong L,Ibrahim R,Dahdah N

更新日期：2020-01-01 00:00:00

abstract：:Optical sectioning endoscopy such as confocal endoscopy offers capabilities to obtain three-dimensional (3D) information from various biological samples by discriminating between the desired in-focus signals and out-of-focus background. However, in general confocal images are formed through point-by-point scanning and...

journal_title：Journal of biophotonics

authors： Lin WT,Lin CY,Singh VR,Luo Y

更新日期：2018-11-01 00:00:00

abstract：:Semiconductor nanoparticles (NPs) became important and wide-used tool for cell imaging because of their unique remarkable properties. Nevertheless, all previous investigations in this area were done on proliferating cells. For the first time, this work demonstrates strong influence of cell active proliferation/contact...

journal_title：Journal of biophotonics

authors： Serdiuk T,Lysenko V,Mognetti B,Skryshevsky V,Géloën A

更新日期：2013-03-01 00:00:00