Label free optical sensor for Avidin based on single gold nanoparticles functionalized with aptamers.

abstract：:In this paper we introduce a custom scanning near-field optical microscope (SNOM) that simultaneously collects reflection and transmission near-field images along with topography. This dual-optical SNOM uses a bent probe, which allows for axial reflection imaging, accurate surface scanning, and easy identification of ...

journal_title：Journal of biophotonics

authors： Kyle JR,Kyle MD,Raghavan R,Budak G,Ozkan CS,Ozkan M

更新日期：2011-03-01 00:00:00

abstract：:We report the use of ultrasound modulated optical tomography (UOT) with heterodyne parallel detection to locally sense and image blood flow deep inside a highly scattering medium. We demonstrate that the UOT signal is sensitive to the speed of the blood flow in the ultrasound focus and present an analytical model that...

journal_title：Journal of biophotonics

authors： Hussain A,Steenbergen W,Vellekoop IM

更新日期：2018-01-01 00:00:00

abstract：:Lasers are used in dentistry for a variety of indications. One of these is the disinfection of root canals or the sterilization of residual caries. Many studies have demonstrated the capacity to kill bacteria for lasers but the fundamental mechanism of the laser effect remains quite unclear. With our experiments we wa...

journal_title：Journal of biophotonics

authors： Hibst R,Graser R,Udart M,Stock K

更新日期：2010-06-01 00:00:00

abstract：:Nacre is a complex biomaterial made of aragonite-tablet bricks and organic mortar that is considerably resilient against breakage. Nacre has been studied with a wide range of laboratory techniques, leading to understanding key fundamentals and informing the creation of bio-inspired materials. In this article, we prese...

journal_title：Journal of biophotonics

authors： Jones JA,Metzler RA,D'Addario AJ,Burgess C,Regan B,Spano S,Cvarch BA,Galvez EJ

更新日期：2018-10-01 00:00:00

abstract：:Cutaneous squamous cell carcinoma (cSCC) is a common skin cancer with metastatic potential. To reduce reoperations due to nonradical excision, there is a need to develop a technique for identification of tumor margins preoperatively. Photoacoustic (PA) imaging is a novel imaging technology that combines the strengths ...

journal_title：Journal of biophotonics

authors： Hult J,Dahlstrand U,Merdasa A,Wickerström K,Chakari R,Persson B,Cinthio M,Erlöv T,Albinsson J,Gesslein B,Sheikh R,Malmsjö M

更新日期：2020-05-01 00:00:00

abstract：:Hyperspectral imaging is a promising technique for resection margin assessment during cancer surgery. Thereby, only a specific amount of the tissue below the resection surface, the clinically defined margin width, should be assessed. Since the imaging depth of hyperspectral imaging varies with wavelength and tissue co...

journal_title：Journal of biophotonics

authors： Kho E,de Boer LL,Post AL,Van de Vijver KK,Jóźwiak K,Sterenborg HJCM,Ruers TJM

更新日期：2019-11-01 00:00:00

abstract：:Optical coherence elastography (OCE) represents the frontier of optical elasticity imaging techniques and focuses on the micro-scale assessment of tissue biomechanics in 3D that is hard to achieve with traditional elastographic methods. Benefit from the advancement of optical coherence tomography, and driven by the in...

journal_title：Journal of biophotonics

authors： Wang S,Larin KV

更新日期：2015-04-01 00:00:00

abstract：:223 Radium (223 Ra) is widely used in nuclear medicine to treat patients with osseous metastatic prostate cancer. In clinical practice 223 Ra cannot be imaged directly; however, gamma photons produced by its short-lived daughter nuclides can be captured by conventional gamma cameras. In this work, we show that 223 Ra ...

journal_title：Journal of biophotonics

authors： Boschi F,De Sanctis F,Spinelli AE

更新日期：2018-04-01 00:00:00

abstract：:In biomedical applications, nanoparticles have demonstrated the potential to eradicate abnormal cells in small localized pathological zones associated with cancer or infections. Here, we introduce a method for nanotechnology-based photothermal (PT) killing of whole organisms considered harmful to humans or the environ...

journal_title：Journal of biophotonics

authors： Foster SR,Galanzha EI,Totten DC,Beneš H,Shmookler Reis RJ,Zharov VP

更新日期：2014-07-01 00:00:00

abstract：:Optical sectioning endoscopy such as confocal endoscopy offers capabilities to obtain three-dimensional (3D) information from various biological samples by discriminating between the desired in-focus signals and out-of-focus background. However, in general confocal images are formed through point-by-point scanning and...

journal_title：Journal of biophotonics

authors： Lin WT,Lin CY,Singh VR,Luo Y

更新日期：2018-11-01 00:00:00

abstract：:Photodynamic inactivation (PDI) is a promising alternative for combating infections caused by antimicrobial resistant bacteria. Pneumonias are among the most worrisome infections because of their high-mortality rate. Previous studies have demonstrated the feasibility of using PDI with extracorporeal light to treat pne...

journal_title：Journal of biophotonics

authors： Kassab G,Cheburkanov V,Willis J,Moule MG,Kurachi C,Yakovlev V,Cirillo JD,Bagnato VS

更新日期：2020-10-01 00:00:00

abstract：:As the field of tissue engineering evolves, there will be an increasingly important need to visualize and track the complex dynamic changes that occur within three-dimensional constructs. Optical coherence tomography (OCT), as an emerging imaging technology applied to biological materials, offers a number of significa...

journal_title：Journal of biophotonics

authors： Liang X,Graf BW,Boppart SA

更新日期：2009-11-01 00:00:00

abstract：:Currently, optical coherence tomography (OCT), is not capable of obtaining molecular information often crucial for identification of disease. To enable molecular imaging with OCT, we have further developed a technique that harnesses transient changes in light absorption in the sample to garner molecular information. A...

journal_title：Journal of biophotonics

authors： Carrasco-Zevallos O,Shelton RL,Kim W,Pearson J,Applegate BE

更新日期：2015-01-01 00:00:00

abstract：:This study presents numerical simulations of UVC light propagation through seven different filtered face respirators (FFR) to determine their suitability for Ultraviolet germicidal inactivation (UVGI). UV propagation was modeled using the FullMonte program for two external light illuminations. The optical properties o...

journal_title：Journal of biophotonics

authors： Lilge L,Manalac A,Weersink M,Schwiegelshohn F,Young-Schultz T,Abdalrhman AS,Wang C,Ngan A,Gu FX,Betz V,Hofmann R

更新日期：2020-12-01 00:00:00

abstract：:We develop a confocal system equipped with optimal elliptical apertures to improve axial point spread function and signal-to-background ratio (SBR) for different detector sizes. By adjusting the parameters of the elliptical apertures, the axial half width at half-maximum can be reduced to 4.986 (described in optical c...

journal_title：Journal of biophotonics

authors： Tang H,Wu C,Gong W,Zheng Y,Zhu X,Wang J,Si K

更新日期：2018-05-01 00:00:00

abstract：:The sun protection factor (SPF) values are currently determined using an invasive procedure, in which the volunteers are irradiated with ultraviolet (UV) light. Non-invasive approaches based on hybrid diffuse reflectance spectroscopy (HDRS) have shown a good correlation with conventional SPF testing. Here, we present ...

journal_title：Journal of biophotonics

authors： Throm CM,Wiora G,Reble C,Schleusener J,Schanzer S,Karrer H,Kolbe L,Khazaka G,Meinke MC,Lademann J

更新日期：2020-10-06 00:00:00

abstract：:The photodetachment of Br(-), I(-) and OH(-) in aqueous solution is studied by 2- and 3-pulse femtosecond spectroscopy. The UV excitation leads to fast electron separation followed by formation of a donor-electron pairs. An additional repump pulse is used for secondary excitation of the intermediates. The 3-pulse tech...

journal_title：Journal of biophotonics

authors： Fischer MK,Gliserin A,Laubereau A,Iglev H

更新日期：2011-03-01 00:00:00

abstract：:The ability to resolve multiple fluorescent emissions from different biological targets in video rate applications, such as endoscopy and intraoperative imaging, has traditionally been limited by the use of filter-based imaging systems. Hyperspectral imaging (HSI) facilitates the detection of both spatial and spectral...

journal_title：Journal of biophotonics

authors： Luthman AS,Dumitru S,Quiros-Gonzalez I,Joseph J,Bohndiek SE

更新日期：2017-06-01 00:00:00

abstract：:In fluctuation-based optical nanoscopy, investigating high-density labeled subcellular structures with high fidelity has been a significant challenge. In this study, based on super-resolution radial fluctuation (SRRF) microscopy, the joint tagging (JT) strategy is employed to enable fast high-density nanoscopic imagin...

journal_title：Journal of biophotonics

authors： Zeng Z,Ma J,Xi P,Xu C

更新日期：2018-09-01 00:00:00

abstract：:We describe a novel, minimally invasive laser technology for skin rejuvenation by creating isolated microscopic lesions within tissue below the epidermis using laser induced optical breakdown. Using an in-house built prototype device, tightly focused near-infrared laser pulses are used to create optical breakdown in t...

journal_title：Journal of biophotonics

authors： Habbema L,Verhagen R,Van Hal R,Liu Y,Varghese B

更新日期：2012-02-01 00:00:00

abstract：:Osteoporosis is a major public health problem worldwide. Here, we present a quantitative multispectral photoacoustic method for the evaluation of bone pathologies which has significant advantages over pure ultrasonic or pure optical methods as it provides both molecular information and bone mechanical status. This is ...

journal_title：Journal of biophotonics

authors： Steinberg I,Turko N,Levi O,Gannot I,Eyal A

更新日期：2016-09-01 00:00:00

abstract：:Atherosclerosis (AS), the leading cause of morbidity and mortality in cardiovascular disease, needs an early detection for treatment and prevention of fatal events. Here, for the first time, we applied gold nanorods (GNRs)-assisted diffusion reflection (DR), a noninvasive technique for in vivo detection of AS in a hig...

journal_title：Journal of biophotonics

authors： Chakraborty R,Ankri R,Leshem-Lev D,Hochhauser E,Kornowski R,Motiei M,Lev EI,Fixler D

更新日期：2019-01-01 00:00:00

abstract：:Semen analysis is performed for evaluation of fertility disorders, however it is susceptible to subjectivity of investigators, and lacking of objective criterion for sperm cell quality remains a problem. There is an ongoing debate on which criteria should be employed to define normal spermatozoa. Here, the aim of our ...

journal_title：Journal of biophotonics

authors： Huang Z,Chen G,Chen X,Wang J,Chen J,Lu P,Chen R

更新日期：2014-09-01 00:00:00

abstract：:We suggest to use a combination of optical tweezers and single-image quantitative differential interference contrast (DIC) emulated by a spatial light modulator (SLM) to study physiological shape changes in thrombocytes after activation and demonstrate the effectiveness of this system for the given task. A specially d...

journal_title：Journal of biophotonics

authors： Khan S,Jesacher A,Nussbaumer W,Bernet S,Ritsch-Marte M

更新日期：2011-09-01 00:00:00

abstract：:Photobiomodulation (PBM) therapy has been noted to promote cell proliferation and growth in many different cell types shown both in vitro and in vivo. Currently, treatment regimens are used in the clinic for a variety of ailments, including wound healing. However, most protocols treat an anatomical site without consid...

journal_title：Journal of biophotonics

authors： Engel KW,Khan I,Arany PR

更新日期：2016-12-01 00:00:00

abstract：:In vivo visualization of the human lymphatic system is limited by the mode of delivery of tracing agents, depth of field and size of the area examined, and specificity of the cell markers used to distinguish lymphatic endothelium from the blood vessels and the surrounding tissues. These limitations are particularly pr...

journal_title：Journal of biophotonics

authors： Lokmic Z

更新日期：2018-08-01 00:00:00

abstract：:Localization microscopy methods like Stochastic Optical Reconstruction Microscopy (STORM) are very well suited for exploring clustering of proteins, as the data inherently provide a list of molecular coordinates. Here we use state-of-art cluster analysis algorithms (DBSCAN) to explore the clustering behaviour of diffe...

journal_title：Journal of biophotonics

authors： Persson H,Potrzebowski W,Potrzebowska K,Svensson LM

更新日期：2019-03-01 00:00:00

abstract：:5-aminolevulinic acid (ALA) and its methylated ester (MAL) are the most common topical agents used in photodynamic therapy (PDT) as precursors of the photosensitizer protoporphyrin IX (PpIX). The induction of newly PpIX depends on incubation time of each photosensitizer in the tissue and the presence of high intralesi...

journal_title：Journal of biophotonics

authors： Lima CA,Goulart VP,Bechara EJ,Correa L,Zezell DM

更新日期：2016-12-01 00:00:00

abstract：:Photoacoustic microscopy (PAM) provides a fundamentally new tool for a broad range of studies of biological structures and functions. However, the use of PAM has been largely limited to small vertebrates due to the large size/weight and the inconvenience of the equipment. Here, we describe a portable optical-resolutio...

journal_title：Journal of biophotonics

authors： Jin T,Guo H,Yao L,Xie H,Jiang H,Xi L

更新日期：2018-04-01 00:00:00

abstract：:A robust method is presented for evaluating the diffusion properties of chemicals in ex vivo biological tissues. Using this method that relies only on thickness and collimated transmittance measurements, the diffusion properties of glycerol, fructose, polypropylene glycol and water in muscle tissues were evaluated. Am...

journal_title：Journal of biophotonics

authors： Carneiro I,Carvalho S,Henrique R,Oliveira LM,Tuchin VV

更新日期：2019-04-01 00:00:00