Abstract:
:Semiconductor nanoparticles (NPs) became important and wide-used tool for cell imaging because of their unique remarkable properties. Nevertheless, all previous investigations in this area were done on proliferating cells. For the first time, this work demonstrates strong influence of cell active proliferation/contact inhibition of proliferation on uptake of NPs. In addition, we show that cell division plays key-role in penetration of silicon carbide based NPs (SiC NPs) inside the cell nucleus. This may very likely concern other types of NPs able to reach the cell nuclei. In particular, observed effect of cell division gives perspectives for future selective cancer treatment with NPs.
journal_name
J Biophotonicsjournal_title
Journal of biophotonicsauthors
Serdiuk T,Lysenko V,Mognetti B,Skryshevsky V,Géloën Adoi
10.1002/jbio.201200066subject
Has Abstractpub_date
2013-03-01 00:00:00pages
291-7issue
3eissn
1864-063Xissn
1864-0648journal_volume
6pub_type
杂志文章abstract::In this review we provide a description of the basic concepts and paradigms currently constituting the foundations of adult stem cell biology, and discuss the role that live imaging techniques have in the development of the field. We focus on live imaging of hematopoietic stem cells (HSCs) as the basic biology and cli...
journal_title:Journal of biophotonics
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abstract::Perfusion and oxygenation are critical parameters of muscle metabolism in health and disease. They have been both the target of many studies, in particular using near-infrared spectroscopy (NIRS). However, difficulties with quantifying NIRS signals have limited a wide dissemination of the method to the clinics. Our ai...
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journal_title:Journal of biophotonics
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journal_title:Journal of biophotonics
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journal_title:Journal of biophotonics
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