A telemetric light delivery system for metronomic photodynamic therapy (mPDT) in rats.

abstract：:Intravascular optical coherence tomography (IV-OCT) is a light-based imaging modality with high resolution, which employs near-infrared light to provide tomographic intracoronary images. Morbidity caused by coronary heart disease is a substantial cause of acute coronary syndrome and sudden cardiac death. The most comm...

journal_title：Journal of biophotonics

authors： Abdolmanafi A,Cheriet F,Duong L,Ibrahim R,Dahdah N

更新日期：2020-01-01 00:00:00

abstract：:Current elastography techniques are limited in application to accurately assess spatially resolved corneal elasticity in vivo for human eyes. The air-puff optical coherence elastography (OCE) with an eye motion artifacts correction algorithm is developed to distinguish the in vivo cornea vibration from the eye motion ...

journal_title：Journal of biophotonics

authors： Jin Z,Chen S,Dai Y,Bao C,Ye S,Zhou Y,Wang Y,Huang S,Wang Y,Shen M,Zhu D,Lu F

更新日期：2020-08-01 00:00:00

abstract：:Photoacoustic imaging (PAI) is a hybrid imaging modality with high resolution and sensitivity that can be beneficial for cancer staging. Due to insufficient endogenous photoacoustic (PA) contrast, the development of exogenous agents is critical in targeting cancerous tumors. The current study demonstrates the feasibil...

journal_title：Journal of biophotonics

authors： Nguyen VP,Park S,Oh J,Wook Kang H

更新日期：2017-08-01 00:00:00

abstract：:Malaria is a life-threatening infectious blood disease affecting humans and other animals caused by parasitic protozoans belonging to the Plasmodium type especially in developing countries. The gold standard method for the detection of malaria is through the microscopic method of chemically treated blood smears. We de...

journal_title：Journal of biophotonics

authors： Singla N,Srivastava V,Mehta DS

更新日期：2018-05-01 00:00:00

abstract：:Myelin is a key component of the peripheral nervous system, whose structure anomaly in the digital skin is implicated in neuropathy. Here we demonstrate an in vivo labeling and imaging technique, capable of visualizing myelin sheaths deep in the mouse digital skin. Through material characterization, we verify that 3-p...

journal_title：Journal of biophotonics

authors： He C,Deng X,Pan Y,Tong S,Kang J,Li J,Qiu P,Wang K

更新日期：2020-12-01 00:00:00

abstract：:The ability to resolve multiple fluorescent emissions from different biological targets in video rate applications, such as endoscopy and intraoperative imaging, has traditionally been limited by the use of filter-based imaging systems. Hyperspectral imaging (HSI) facilitates the detection of both spatial and spectral...

journal_title：Journal of biophotonics

authors： Luthman AS,Dumitru S,Quiros-Gonzalez I,Joseph J,Bohndiek SE

更新日期：2017-06-01 00:00:00

abstract：:We developed an optical imaging method based on a feedback principle in which the specific scan pattern is adapted according to the shape of the sample. The feedback approach produces nanometer-resolved 3D images of very small and moving features in live cells in seconds. We show images of microvilli in live cultured ...

journal_title：Journal of biophotonics

authors： Lanzano L,Digman MA,Fwu P,Giral H,Levi M,Gratton E

更新日期：2011-06-01 00:00:00

abstract：:In vivo microscopy has recently become a gold standard in lung immunology studies involving small animals, largely benefiting from the democratization of multiphoton microscopy allowing for deep tissue imaging. This technology represents currently our only way of exploring the lungs and inferring what happens in human...

journal_title：Journal of biophotonics

authors： Fiole D,Tournier JN

更新日期：2016-09-01 00:00:00

abstract：:In preclinical researches, bioluminescence tomography (BLT) has widely been used for tumor imaging and monitoring, imaged-guided tumor therapy, and so forth. For these biological applications, both tumor spatial location and morphology analysis are the leading problems needed to be taken into account. However, most ex...

journal_title：Journal of biophotonics

authors： Guo H,Gao L,Yu J,He X,Wang H,Zheng J,Yang X

更新日期：2020-04-01 00:00:00

abstract：:Hyperspectral imaging is a promising technique for resection margin assessment during cancer surgery. Thereby, only a specific amount of the tissue below the resection surface, the clinically defined margin width, should be assessed. Since the imaging depth of hyperspectral imaging varies with wavelength and tissue co...

journal_title：Journal of biophotonics

authors： Kho E,de Boer LL,Post AL,Van de Vijver KK,Jóźwiak K,Sterenborg HJCM,Ruers TJM

更新日期：2019-11-01 00:00:00

abstract：:The advent of moderate dilatations in ascending aortas is often accompanied by structural modifications of the main components of the aortic tissue, elastin and collagen. In this study, we have undertaken an approach based on FTIR microscopy coupled to a curve-fitting procedure to analyze secondary structure modificat...

journal_title：Journal of biophotonics

authors： Bonnier F,Rubin S,Debelle L,Ventéo L,Pluot M,Baehrel B,Manfait M,Sockalingum GD

更新日期：2008-08-01 00:00:00

abstract：:Previous studies for melanin visualization in the retinal pigment epithelium (RPE) have exploited either its absorption properties (using photoacoustic tomography or photothermal optical coherence tomography [OCT]) or its depolarization properties (using polarization sensitive OCT). However, these methods are only sui...

journal_title：Journal of biophotonics

authors： Harper DJ,Konegger T,Augustin M,Schützenberger K,Eugui P,Lichtenegger A,Merkle CW,Hitzenberger CK,Glösmann M,Baumann B

更新日期：2019-12-01 00:00:00

abstract：:In fluctuation-based optical nanoscopy, investigating high-density labeled subcellular structures with high fidelity has been a significant challenge. In this study, based on super-resolution radial fluctuation (SRRF) microscopy, the joint tagging (JT) strategy is employed to enable fast high-density nanoscopic imagin...

journal_title：Journal of biophotonics

authors： Zeng Z,Ma J,Xi P,Xu C

更新日期：2018-09-01 00:00:00

abstract：:This study presents numerical simulations of UVC light propagation through seven different filtered face respirators (FFR) to determine their suitability for Ultraviolet germicidal inactivation (UVGI). UV propagation was modeled using the FullMonte program for two external light illuminations. The optical properties o...

journal_title：Journal of biophotonics

authors： Lilge L,Manalac A,Weersink M,Schwiegelshohn F,Young-Schultz T,Abdalrhman AS,Wang C,Ngan A,Gu FX,Betz V,Hofmann R

更新日期：2020-12-01 00:00:00

abstract：:Achieving a maximal safe extent of resection during brain tumor surgery is the goal for improved patient prognosis. Fluorescence-guided neurosurgery using 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX has thereby become a valuable tool enabling a high frequency of complete resections and a prolonged progress...

journal_title：Journal of biophotonics

authors： Erkkilä MT,Bauer B,Hecker-Denschlag N,Madera Medina MJ,Leitgeb RA,Unterhuber A,Gesperger J,Roetzer T,Hauger C,Drexler W,Widhalm G,Andreana M

更新日期：2019-06-01 00:00:00

abstract：:This paper comments on the article "Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography" by Qian Li et al. The authors propose a method to determine the pulse wave velocity in retinal arteries and veins. This method should enable a noninvasive determination of biomechanical prope...

journal_title：Journal of biophotonics

authors： Spahr H,Hillmann D,Pfäffle C,Hüttmann G

更新日期：2018-02-01 00:00:00

abstract：:Osteocytes are the most abundant cells in bone and always the focus of bone research. They are embedded in the highly scattering mineralized bone matrix. Consequently, visualizing osteocytes deep in bone with subcellular resolution poses a major challenge for in vivo bone research. Here we overcome this challenge by d...

journal_title：Journal of biophotonics

authors： Wang K,Du Y,Liu H,Gan M,Tong S,Wen W,Zhuang Z,Qiu P

更新日期：2019-04-01 00:00:00

abstract：:Skin fibrosis is a chronic debilitating feature of several skin diseases that lead to characteristic increases in dermal fibroblast proliferation and collagen deposition through upregulation in components of the transforming growth factor beta (TGF-B)/SMAD pathway. In contrast to ultraviolet phototherapy, high-fluence...

journal_title：Journal of biophotonics

authors： Mamalis A,Koo E,Tepper C,Jagdeo J

更新日期：2019-05-01 00:00:00

abstract：:Initially, it has been shown that the phase thickness and refractivity (the latter interpreted as the difference of the refractivity indices of an object and surrounding medium) depend on the functional state of mitochondria. The refractivity of various objects decreased in response to energy depletion. This dependenc...

journal_title：Journal of biophotonics

authors： Tychinsky V

更新日期：2009-09-01 00:00:00

abstract：:We introduce a unique method for laser-propelling individual cells over distances of 10s of cm through stationary liquid in a microfluidic channel. This is achieved by using liquid-filled hollow-core photonic crystal fiber (HC-PCF). HC-PCF provides low-loss light guidance in a well-defined single mode, resulting in hi...

journal_title：Journal of biophotonics

authors： Unterkofler S,Garbos MK,Euser TG,St J Russell P

更新日期：2013-09-01 00:00:00

abstract：:One of the challenges in transcranial low-level laser therapy (LLLT) is to optimally choose illumination parameters, such as wavelength. However, there is sparse study on the wavelengths comparison especially on human transcranial LLLT. Here, we employed Monte Carlo modeling and visible human phantom to compute the pe...

journal_title：Journal of biophotonics

authors： Wang P,Li T

更新日期：2019-02-01 00:00:00

abstract：:Photobiomodulation (PBM) therapy has been noted to promote cell proliferation and growth in many different cell types shown both in vitro and in vivo. Currently, treatment regimens are used in the clinic for a variety of ailments, including wound healing. However, most protocols treat an anatomical site without consid...

journal_title：Journal of biophotonics

authors： Engel KW,Khan I,Arany PR

更新日期：2016-12-01 00:00:00

abstract：:Cutaneous squamous cell carcinoma (cSCC) is a common skin cancer with metastatic potential. To reduce reoperations due to nonradical excision, there is a need to develop a technique for identification of tumor margins preoperatively. Photoacoustic (PA) imaging is a novel imaging technology that combines the strengths ...

journal_title：Journal of biophotonics

authors： Hult J,Dahlstrand U,Merdasa A,Wickerström K,Chakari R,Persson B,Cinthio M,Erlöv T,Albinsson J,Gesslein B,Sheikh R,Malmsjö M

更新日期：2020-05-01 00:00:00

abstract：:Drowsy driving contributes to ~20% of all traffic accidents worldwide. Onsite monitoring the mental condition of a driver and forewarning may be a preventive solution to reduce occurrence of drowsiness and potential accidents. Functional near-infrared spectroscopy (fNIRS) has been successfully utilized in hemodynamics...

journal_title：Journal of biophotonics

authors： Li T,Lin Y,Gao Y,Zhong F

更新日期：2018-12-01 00:00:00

abstract：:A novel hybrid method which combines sub-wavelength-scale phase measurements and pixel-scale displacement tracking for robust strain mapping in compressional optical coherence elastography is proposed. Unlike majority of OCE methods it does not rely on initial reconstruction of displacements and does not suffer from t...

journal_title：Journal of biophotonics

authors： Zaitsev VY,Matveyev AL,Matveev LA,Gelikonov GV,Gubarkova EV,Gladkova ND,Vitkin A

更新日期：2016-05-01 00:00:00

abstract：:Surface-enhanced Raman scattering (SERS) is highly sensitive and label-free analytical technique based on Raman spectroscopy aided by field-multiplying plasmonic nanostructures. We report the use of SERS measurements of patient urine in conjunction with biostatistical algorithms to assess the treatment response of pro...

journal_title：Journal of biophotonics

authors： Ma Y,Chi J,Zheng Z,Attygalle A,Kim IY,Du H

更新日期：2021-01-01 00:00:00

abstract：:We report a compact, cost-effective tuned amplifier for frequency-selective amplification of the modulated signal in heterodyne detected nonlinear optical microscopy. Our method improved the signal to noise ratio by an order of magnitude compared to conventional lock-in detection, as demonstrated through stimulated Ra...

journal_title：Journal of biophotonics

authors： Slipchenko MN,Oglesbee RA,Zhang D,Wu W,Cheng JX

更新日期：2012-10-01 00:00:00

abstract：:Laser tweezers Raman spectroscopy (LTRS) as a label-free and noninvasive technology has been proven to be an ideal tool for analysis of single living cells, which provides important fingerprint information without interference from surrounding environments. For the first time, LTRS system was successfully used to exam...

journal_title：Journal of biophotonics

authors： Liu M,Liu X,Huang Z,Tang X,Lin X,Xu Y,Chen G,Kwok HF,Lin Y,Feng S

更新日期：2019-03-01 00:00:00

abstract：:Micro-/nanosphere-mediated femtosecond laser cell perforation is one of the high throughput technologies used for macro-molecule-delivery into multiple cells. We have demonstrated the delivery of plasmid-DNA/liposome complexes into cells using biodegradable polymer microspheres and a femtosecond laser and investigated...

journal_title：Journal of biophotonics

authors： Ishii A,Hiruta Y,Heinemann D,Heisterkamp A,Kanazawa H,Terakawa M

更新日期：2017-12-01 00:00:00

abstract：:Acridine orange (AO) staining is used to diagnose DNA fragmentation status in sperm cells. Interferometric phase microscopy (IPM) is an optical imaging method based on digital holographic microscopy that provides quantitative morphological and refractive index imaging of cells in vitro without the need for staining. W...

journal_title：Journal of biophotonics

authors： Barnea I,Karako L,Mirsky SK,Levi M,Balberg M,Shaked NT

更新日期：2018-11-01 00:00:00