Abstract：
:We present a novel silicon photonic biosensor using phase-shifted Bragg gratings in a slot waveguide. The optical field is concentrated inside the slot region, leading to efficient light-matter interaction. The Bragg gratings are formed with sidewall corrugations on the outside of the waveguide, and a phase shift is introduced to create a sharp resonant peak within the stop band. We experimentally demonstrate a high sensitivity of 340 nm/RIU measured in salt solutions and a high quality factor of 1.5 × 10⁴, enabling a low intrinsic limit of detection of 3 × 10⁻⁴ RIU. Furthermore, the silicon device was fabricated by a CMOS foundry, facilitating high-volume and low-cost production. Finally, we demonstrate the device's ability to interrogate specific biomolecular interactions, resulting in the first of its kind label-free biosensor.
journal_name
J Biophotonicsjournal_title
Journal of biophotonicsauthors
Wang X,Flueckiger J,Schmidt S,Grist S,Fard ST,Kirk J,Doerfler M,Cheung KC,Ratner DM,Chrostowski Ldoi
10.1002/jbio.201300012subject
Has Abstractpub_date
2013-10-01 00:00:00pages
821-8issue
10eissn
1864-063Xissn
1864-0648journal_volume
6pub_type
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